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Showing 1–24 of 155 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Heating Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Safety of Pulsing Heating Device Use on the Skin

NCT05427877
View directory record Official record
Conditions
Pain
Interventions
Heating device (Heatwave Technology)
Device
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 21, 2022 · Synced Sep 8, 2026, 4:59 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Efficacy and Safety of Synera in Osteoarthritis Pain

NCT01654302
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Synera, Inactive patch
Drug
Lead sponsor
Thomas J. Schnitzer
Other
Eligibility
40 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 11, 2015 · Synced Sep 8, 2026, 4:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Radiofrequency and Pulsed Electromagnetic Field Treatment of Skin Laxity of the Mon Pubis, Labia and Vaginal Introitus

NCT02770287
View directory record Official record
Conditions
Skin Laxity
Interventions
Venus Freeze Diamond Polar
Device
Lead sponsor
Venus Concept
Industry
Eligibility
25 Years to 65 Years · Female only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Torrance, California
Source: ClinicalTrials.gov public record
Updated Apr 16, 2020 · Synced Sep 8, 2026, 4:59 PM EDT
Completed Not applicable Interventional

MR Guided Focused Ultrasound for Treatment of Neuropathic Pain

NCT03111277
View directory record Official record
Conditions
Severe Neuropathic Pain Due to Radiculopathy or Radicular Injury, Spinal Cord Injuries, Phantom Limb Pain
Interventions
Experimental: ExAblate Transcranial treatment
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
21 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 11, 2022 · Synced Sep 8, 2026, 4:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Soft Tissue Mobilization for Lumbopelvic Pain in the Third Trimester of Pregnancy

NCT03433404
View directory record Official record
Conditions
Low Back Pain, Pregnancy
Interventions
Soft Tissue Mobilization, Soft Tissue Massage
Procedure
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Jul 5, 2023 · Synced Sep 8, 2026, 4:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Hot Water Immersion on Heart Rate Variability and Glucose

NCT06193291
View directory record Official record
Conditions
Glucose Tolerance, HRV
Interventions
Feet heating, Calf heating
Procedure
Lead sponsor
San Diego State University
Other
Eligibility
18 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jan 7, 2024 · Synced Sep 8, 2026, 4:59 PM EDT
Recruiting Not applicable Interventional

Leg Heat Therapy in Peripheral Artery Disease

NCT05465070
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
Leg heat therapy, Sham Control
Device
Lead sponsor
Indiana University
Other
Eligibility
50 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 16, 2026 · Synced Sep 8, 2026, 4:59 PM EDT
Recruiting Not applicable Interventional

Home-Based Heat Therapy in Spinal Cord Injury to Improve Cardiovascular Health

NCT07317843
View directory record Official record
Conditions
SCI - Spinal Cord Injury
Interventions
HEAT - Passive Heat Therapy, Sham (No Treatment)
Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 60 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 8, 2026, 4:59 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Transdermal Patch CVD 2000: The Effect of Heat on Fentanyl Release From Fentanyl TDSs in Healthy Adults

NCT02486016
View directory record Official record
Conditions
Peer Review, Research
Interventions
Duragesic reference fentanyl TDS, Apotex generic fentanyl TDS, Mylan generic fentanyl TDS
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 45 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 22, 2020 · Synced Sep 8, 2026, 4:59 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Evaluating Impact of Systane iLux on Dryness Symptoms and Wearing Time in Contact Lens Users

NCT05306561
View directory record Official record
Conditions
Meibomian Gland Dysfunction, Dry Eye
Interventions
Systane iLux thermal pulsation treatment
Procedure
Lead sponsor
Periman Eye Institute
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 17, 2023 · Synced Sep 8, 2026, 4:59 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Heating Pad for in Office Cystoscopy and Urodynamic Testing

NCT05981794
View directory record Official record
Conditions
Anxiety, Pain, Distress, Emotional
Interventions
Electrical heating pad, Sham heating pad
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 22, 2025 · Synced Sep 8, 2026, 4:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Daily Stress and Vascular Function in Midlife as a Risk Factor for Cognitive Decline

NCT06466655
View directory record Official record
Conditions
Middle-aged Adults, Major Depressive Disorder
Interventions
MitoTempol, Lactated Ringer's (control)
Drug
Lead sponsor
University of Delaware
Other
Eligibility
40 Years to 55 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Sep 8, 2026, 4:59 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Defining a PK and PD Model for Peripheral Analgesia After IV Oxytocin

NCT05929339
View directory record Official record
Conditions
Acute Pain, Chronic Pain, Healthy Volunteer
Interventions
Oxytocin
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 75 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Sep 8, 2026, 4:59 PM EDT
Completed Not applicable Interventional

Heat Therapy in Older Hypertensive Women

NCT03857490
View directory record Official record
Conditions
Essential Hypertension
Interventions
Lower leg heat therapy
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
60 Years to 85 Years · Female only
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Sep 8, 2026, 4:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

BACK4 Safety Evaluation

NCT07153900
View directory record Official record
Conditions
Safety and Tolerability in Healthy Subjects
Interventions
Treatment with BACK4 System
Device
Lead sponsor
SWIMS America Corp.
Industry
Eligibility
22 Years to 55 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Birmingham, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 1, 2026 · Synced Sep 8, 2026, 4:59 PM EDT
Recruiting Not applicable Interventional

Peripheral Neuroimmune Mechanisms of Hyperthermia

NCT05366270
View directory record Official record
Conditions
Hyperthermia, Major Depressive Disorder, Inflammation
Interventions
WBH, Sham
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 9, 2023 · Synced Sep 8, 2026, 4:59 PM EDT
Recruiting Phase 1 Interventional

Heat Therapy in Type 2 Diabetes

NCT06596967
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Heat therapy, Sham
Device
Lead sponsor
Purdue University
Other
Eligibility
55 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 8, 2026, 4:59 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Evaluation of the Effect of Fasting and Exercise on Uptake of Tc-99m Sestamibi in Breast Tissue

NCT01944215
View directory record Official record
Conditions
Molecular Imaging
Interventions
Meal, Exercise, Sestamibi, Caffeine Tablet, External Heating
Dietary Supplement · Other · Radiation + 1 more
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years to 70 Years · Female only
Enrollment
154 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced Sep 8, 2026, 4:59 PM EDT
Completed Not applicable Interventional

Reduction of Pain Caused by Biologic Drugs in Psoriasis

NCT02168244
View directory record Official record
Conditions
Psoriasis, Pain
Interventions
Heating Pack, Ice pack
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
Not listed
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 12, 2016 · Synced Sep 8, 2026, 4:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Multimodal Haptic Feedback for Plantar Sensory Substitution

NCT06232512
View directory record Official record
Conditions
Hypoesthesia
Interventions
Haptic Device
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 85 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Sep 8, 2026, 4:59 PM EDT
Not listed Not applicable Interventional

A Novel Non-Pharmacological Treatment of Diabetic Neuropathy

NCT05414968
View directory record Official record
Conditions
Diabetic Peripheral Neuropathy
Interventions
Non-pharmacological Heat, Pressure, and Vibration
Device
Lead sponsor
Auburn University
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 3, 2023 · Synced Sep 8, 2026, 4:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Feet and Calf Heating on Glucose Tolerance

NCT04232098
View directory record Official record
Conditions
Postprandial Hyperglycemia, Heart Rate Variability
Interventions
Heat to ankle, Heat to calf
Other
Lead sponsor
San Diego State University
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 19, 2024 · Synced Sep 8, 2026, 4:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

THRIVE+ Pharmacy Liaison-Patient Navigation Intervention

NCT03919084
View directory record Official record
Conditions
Healthcare Utilization
Interventions
THRIVE screening and referral, Pharmacy Care Program services, Patient Navigation Services, Motivational Interviewing, Linkage to Community Partner Organization
Other
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years to 64 Years
Enrollment
364 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 17, 2021 · Synced Sep 8, 2026, 4:59 PM EDT
Active, not recruiting Early Phase 1 Interventional Accepts healthy volunteers

Heat, Microvascular Function and Aging

NCT06633198
View directory record Official record
Conditions
Aging
Interventions
Passive Heating, L-NAME
Procedure · Drug
Lead sponsor
William Hughes
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 8, 2026, 4:59 PM EDT