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ClinicalTrials.gov public records Last synced Nov 6, 2026, 5:44 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1393–1416 of 2,754 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: High Activity Clear all

Conditions: Dementia With Lewy Bodies, Parkinson Disease Dementia, Healthy Controls
Interventions: Syn-One skin biopsy, Multi modal MRI, Assessment of dynamic EEG features over 48-hour periods across all study aims, Plasma biomarkers, Galantamine HBr extended-release 8mg capsules (8mg ER).; Procedure · Diagnostic Test · Drug
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 50 Years to 89 Years
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Substance Abuse, Substance Dependence
Interventions: Chestnut Bloomington Outpatient (CBOP), Motivational Enhancement Therapy/Cognitive Behavior Treatment (MET/CBT 7), Assertive Continuing Care (ACC); Behavioral
Lead sponsor: Chestnut Health Systems; Other
Eligibility: 12 Years to 18 Years
Enrollment: 320 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2008
U.S. locations: 1
States / cities: Bloomington, Illinois

Conditions: COVID-19
Interventions: VXA-CoV2-1.1-S, Placebo Tablets; Drug · Other
Lead sponsor: Vaxart; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 66 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 4
States / cities: Long Beach, California • Wichita, Kansas • Cleveland, Ohio + 1 more

Conditions: HIV Infections
Interventions: Autologous Dendritic Cell HIV Vaccination; Biological
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years and older
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2003
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Cardiovascular Diseases, Atherosclerosis, Postmenopause, Heart Diseases
Interventions: Diet, fat-restricted, Exercise; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 52 Years to 60 Years · Female only
Enrollment: 508 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2010
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Colitis, Ulcerative
Interventions: Low-dose MH002, High-dose MH002, Placebo; Drug
Lead sponsor: MRM Health NV; Industry
Eligibility: 16 Years and older
Enrollment: 204 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 6
States / cities: Miami, Florida • Orlando, Florida • Palmetto Bay, Florida + 3 more

Conditions: Drug Abuse
Interventions: Computer-delivered Brief Intervention (CBI), Intervener-delivered Brief Intervention (IBI), Adapted Motivational Enhancement Therapy (AMET), Enhanced Usual Care (EUC); Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 60 Years
Enrollment: 878 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Flint, Michigan

Conditions: Crohn's Disease (CD)
Interventions: Vedolizumab IV; Drug
Lead sponsor: Takeda; Industry
Eligibility: 2 Years to 17 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 22
States / cities: Phoenix, Arizona • Los Angeles, California • San Diego, California + 19 more

Conditions: Immune Surveillance, Stem Cell Surveillance
Interventions: A low dose of seaweed extract, A high dose of seaweed extract, Placebo; Dietary Supplement
Lead sponsor: Natural Immune Systems Inc; Other
Eligibility: 18 Years to 75 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Klamath Falls, Oregon

Conditions: Cardiovascular Diseases, Heart Diseases, Atherosclerosis, HIV Infections, Cardiomyopathy, Hypertrophic
Interventions: Not listed
Lead sponsor: University of Miami; Other
Eligibility: Up to 2 Years
Enrollment: 167 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2006
U.S. locations: 5
States / cities: Miami, Florida • Chicago, Illinois • Boston, Massachusetts + 2 more

Conditions: Peripheral Arterial Disease
Interventions: Text Messages, Phone Calls, Handout; Other
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 50 Years and older
Enrollment: 69 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016
U.S. locations: 1
States / cities: Wichita, Kansas

Conditions: Anemia
Interventions: Salsalate, Placebo; Drug
Lead sponsor: Harvey Jay Cohen; Other
Eligibility: 65 Years and older
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 12
States / cities: Summerfield, Florida • Savannah, Georgia • Chicago, Illinois + 8 more

Conditions: Insomnia, Depression
Interventions: Cognitive Behavioral Therapy for Insomnia; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Reduction in Heavy Drinking in Patients With HIV
Interventions: Naltrexone, Placebo + Medication Management/Medication Coaching; Drug · Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2017
U.S. locations: 2
States / cities: New Haven, Connecticut

Conditions: Physical Activity
Interventions: Free physical activity classes, Frequent User; Behavioral
Lead sponsor: RAND; Other
Eligibility: 18 Years and older
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Santa Monica, California

Conditions: Advanced Solid Tumor Historically Known for High EphA2 Expression, Urothelial Cancer, Ovarian Cancer, Non-small Cell Lung Cancer, Head and Neck Cancer, Triple Negative Breast Cancer, Gastric/Upper Gastrointestinal Cancer
Interventions: BT5528, Nivolumab; Drug
Lead sponsor: BicycleTx Limited; Industry
Eligibility: 18 Years and older
Enrollment: 288 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2027
U.S. locations: 12
States / cities: Encinitas, California • Orange, California • Denver, Colorado + 9 more

Conditions: End Stage Renal Disease
Interventions: High Intensity Interval Training; Other
Lead sponsor: Francesc Marti; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Rheumatoid Arthritis
Interventions: Low dose ORTD-1, Low dose vehicle control, High dose ORTD-1, High dose vehicle control; Drug
Lead sponsor: Oryn Therapeutics, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 3
States / cities: Los Angeles, California • Tustin, California • Miami, Florida

Conditions: Spastic Cerebral Palsy
Interventions: Selective movement of individual lower limb joints, Knee joint strengthening at high velocities, Ankle controlled gaming, Functional activities based on child and parental goals, Sensori-motor exercises; Other
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 5 Years to 18 Years
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: HIV, Hypertension, Exercise
Interventions: Exercise; Behavioral
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 50 Years and older
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Fatigue
Interventions: Veillonella atypica FB0054, Placebo; Dietary Supplement · Other
Lead sponsor: FitBiomics, Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 153 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Systemic Lupus Erythematosus
Interventions: Anifrolumab, Placebo; Drug
Lead sponsor: AstraZeneca; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 6
States / cities: Thousand Oaks, California • Orlando, Florida • New York, New York + 3 more

Conditions: Advanced Solid Tumors Cancer, MSI-H Cancer
Interventions: NDI-219216; Drug
Lead sponsor: Nimbus Wadjet, Inc.; Industry
Eligibility: 18 Years to 99 Years
Enrollment: 134 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2031
U.S. locations: 11
States / cities: Los Angeles, California • Chicago, Illinois • Louisville, Kentucky + 8 more

Conditions: Temperature, Clothing, Sex, Age, Adiposity
Interventions: Effects of Clothing, Effects of Temperature, Low Physical Activity, High Physical Activity, Direct calorimetry and doubly labeled water; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years and older
Enrollment: 39 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Aurora, Colorado

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Elucidating the Role of Cholinergic Degeneration in Cognitive Fluctuations in Lewy Body Dementia

Adolescent Outpatient and Continuing Care Study

A Ph 2 Trial With an Oral Tableted COVID-19 Vaccine

HIV Vaccine Designed for HIV Infected Adults Taking Anti-HIV Drugs

Reduction of Triglycerides in Women on Hormone Replacement Therapy

Confirmatory Clinical Study in Active Ulcerative Colitis

Healthier You: Optimizing Screening, Brief Interventions, and Referral to Treatment (SBIRT) in the Emergency Department

A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)

Rapid Effects on Antioxidant Status, Immune Alertness, and Regenerative Activity

Effects of Highly Active Anti-Retroviral Therapy on Cardiovascular Health in Infants of HIV-Infected Mothers

Text Messaging to Promote Walking Among Latino Adults at Risk for Peripheral Arterial Disease

Trial To Evaluate the Efficacy of Oral Salsalate in the Treatment of Older Adults With Unexplained Anemia

Sleep Mechanisms Of Regulating Emotions

Reducing Heavy Drinking to Optimize HIV/AIDS Treatment and Prevention

Promoting Physical Activity In High Poverty Neighborhoods

Study BT5528-100 in Patients With Advanced Solid Tumors Associated With EphA2 Expression

High-Intensity Interval Training and Regulatory T Cells

Randomized, Double-blind, Vehicle Controlled, Repeat Dose Comparative Study in RA Patients Managed With DMARDs

A Physical Therapy Program Targeting Lower Extremity Selective Motor Control in Children With Spastic Cerebral Palsy

Feasibility of HIIT in Older Adults with HIV and Hypertension

A Study of the Next-generation Probiotic, Veillonella Atypica FB0054 vs Placebo

A Study to Characterize the Pharmacokinetics, Pharmacodynamics, and Safety of Anifrolumab in Adult Type I Interferon Test High Systemic Lupus Erythematosus Subject With Active Skin Manifestations

A Study to Assess the Safety, Tolerability, and Efficacy of NDI-219216 in Patients With Advanced Solid Tumors.

Measuring Free-living Energy Expenditure Using Direct Calorimetry