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Showing 1–24 of 96 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: High Fat and Calorie Meal Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Dietary Lipid Induced Insulin Resistance

NCT02757560
View directory record Official record
Conditions
Insulin Resistance
Interventions
SFA diet, MUFA diet, CARB diet
Other
Lead sponsor
Phoenix VA Health Care System
Federal
Eligibility
40 Years to 75 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2020
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 31, 2019 · Synced Sep 26, 2026, 11:56 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Inflammation, Polyphenols, and Genetics

NCT01568827
View directory record Official record
Conditions
Overweight, Obese
Interventions
Blackraspberry Slurry
Dietary Supplement
Lead sponsor
Ohio State University
Other
Eligibility
55 Years and older · Male only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 26, 2016 · Synced Sep 26, 2026, 11:56 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Study to Evaluate Safety, Tolerability, and the PK Profile of TBI-223 in Healthy Subjects

NCT04865536
View directory record Official record
Conditions
Tuberculosis, Tuberculosis, Pulmonary
Interventions
TBI-223 1800 mg, TBI-223 2400mg, TBI-223 Placebo
Drug
Lead sponsor
Global Alliance for TB Drug Development
Other
Eligibility
19 Years to 50 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Fair Lawn, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Sep 26, 2026, 11:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Epigenetic Effects of a Single Bout of Exercise on Cardiovascular Risk Factors and the Metabolome

NCT05034380
View directory record Official record
Conditions
Obesity, Type 2 Diabetes, Cardiovascular Diseases, Acute Exercise
Interventions
Acute exercise
Behavioral
Lead sponsor
East Carolina University
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 4, 2021 · Synced Sep 26, 2026, 11:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Monocyte Priming When Consuming a Western Diet

NCT05348395
View directory record Official record
Conditions
Heart Diseases
Interventions
Experimental diet
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
20 Years to 45 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Sep 26, 2026, 11:56 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

A Study to Compare the Bioavailability (BA) of Dexlansoprazole Delayed-release Capsules

NCT03801148
View directory record Official record
Conditions
Healthy Volunteers
Interventions
30 mg dexlansoprazole capsules manufactured at TOB, 30 mg dexlansoprazole capsules manufactured at TPC, 60 mg dexlansoprazole capsules manufactured at TOB, 60 mg dexlansoprazole capsules manufactured at TPC
Drug
Lead sponsor
Takeda
Industry
Eligibility
18 Years to 55 Years
Enrollment
122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 18, 2020 · Synced Sep 26, 2026, 11:56 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

A Study Investigating the Effect of Food and Esomeprazole on the Single Oral Dose Pharmacokinetics of Alectinib (RO5424802) in Healthy Volunteers.

NCT02023125
View directory record Official record
Conditions
Healthy Volunteer
Interventions
Alectinib, Esomeprazole, High Fat and Calorie Meal, Standard Meal
Drug · Other
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
18 Years to 55 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Oct 6, 2016 · Synced Sep 26, 2026, 11:56 PM EDT
Completed Not applicable Interventional Results available

Anti-inflammatory Effects of the Fiber

NCT02868788
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
dietary fiber, HFHC meal
Dietary Supplement · Other
Lead sponsor
University at Buffalo
Other
Eligibility
18 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Oct 16, 2024 · Synced Sep 26, 2026, 11:56 PM EDT
Enrolling by invitation Phase 2 Interventional

A Study for Participants Who Participated in Prior Clinical Studies of ASTX727 (Standard Dose)

NCT04093570
View directory record Official record
Conditions
Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia, Myelodysplastic Syndromes
Interventions
ASTX727
Drug
Lead sponsor
Taiho Oncology, Inc.
Industry
Eligibility
18 Years and older
Enrollment
332 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
21
States / cities
Fountain Valley, California • Plantation, Florida • Chicago, Illinois + 14 more
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Sep 26, 2026, 11:56 PM EDT
Completed Phase 1 Interventional

GSK1120212 Food-effect Study

NCT01371487
View directory record Official record
Conditions
Cancer
Interventions
GSK1120212
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
3
States / cities
Detroit, Michigan • Nashville, Tennessee • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Nov 12, 2017 · Synced Sep 26, 2026, 11:56 PM EDT
Completed Phase 1 Interventional

Effect of Food on Blood Levels of ASTX727

NCT03813186
View directory record Official record
Conditions
Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, Acute Myeloid Leukemia
Interventions
ASTX727 + Day 2 Food, ASTX727 + Day 4 Food
Drug
Lead sponsor
Astex Pharmaceuticals, Inc.
Industry
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
4
States / cities
Buffalo, New York • Canton, Ohio • Nashville, Tennessee + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 1, 2024 · Synced Sep 26, 2026, 11:56 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Energy Expenditure and Substrate Oxidation in a Whole Room Calorimeter

NCT04061369
View directory record Official record
Conditions
Overweight, Obesity, Body Weight
Interventions
Low fat meal, Moderate fat meal, High fat meal, High fat liquid meal
Other
Lead sponsor
USDA, Western Human Nutrition Research Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated May 14, 2023 · Synced Sep 26, 2026, 11:56 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study To Evaluate The Effect Of Food On The Behavior Of Tofacitinib Modified Release 11 Milligram Tablets In Healthy Western And Japanese Volunteers

NCT02084875
View directory record Official record
Conditions
Healthy
Interventions
tofacitinib modified-release (MR) formulation
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 55 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Glendale, California
Source: ClinicalTrials.gov public record
Updated Nov 29, 2018 · Synced Sep 26, 2026, 11:56 PM EDT
Completed Not applicable Interventional

The Effects of Nutrition Supplementation and Education on the Healing of Diabetic Foot Ulcer (DFU)

NCT04055064
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
glucose control nutritional shake, nutrition education
Dietary Supplement
Lead sponsor
Florida State University
Other
Eligibility
30 Years to 70 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Aug 12, 2019 · Synced Sep 26, 2026, 11:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of High Fat Diet on Muscle Metabolism

NCT02328235
View directory record Official record
Conditions
Diabetes
Interventions
High Saturated Fat Diet
Other
Lead sponsor
Kevin Davy
Other
Eligibility
18 Years to 40 Years · Male only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Blacksburg, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 26, 2026, 11:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

APOE Genotype and Diet Influences on Alzheimer's Biomarkers

NCT03070535
View directory record Official record
Conditions
Alzheimer's Disease; Dementia
Interventions
HIGH and LOW meal ingestion
Other
Lead sponsor
University of Washington
Other
Eligibility
55 Years and older
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Sep 26, 2026, 11:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Increased Protein at Breakfast for Weight Management in Overweight Adolescents

NCT03146442
View directory record Official record
Conditions
Obesity, Adolescent
Interventions
Breakfast
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
13 Years to 21 Years
Enrollment
103 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Oct 30, 2023 · Synced Sep 26, 2026, 11:56 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

A Phase 1 Single Ascending Dose and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of VBP15 in Healthy Adult Subjects

NCT02415439
View directory record Official record
Conditions
Healthy
Interventions
VBP15, Placebo
Drug
Lead sponsor
ReveraGen BioPharma, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
86 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Lenexa, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 9, 2017 · Synced Sep 26, 2026, 11:56 PM EDT
Terminated Not applicable Interventional

Reducing Insulin, Growth Hormones, and Tumors

NCT03785808
View directory record Official record
Conditions
Diet Modification, Lung Cancer
Interventions
Special Diet Therapy (low-carb), Special Diet Therapy (low-fat), Special Diet Therapy (USDA control)
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 11, 2019 · Synced Sep 26, 2026, 11:56 PM EDT
Completed Not applicable Interventional Results available

Targeting Obesity to Optimize Health in Cardiac Rehab (TOPCARE)

NCT03423238
View directory record Official record
Conditions
Obesity, Weight Loss, CHD - Coronary Heart Disease
Interventions
Exercise, Health Education, Exercise Compliance, Calorie-Restricted Diet, Behavioral Modification, Weight-Loss Compliance, Dietary Counseling
Other · Behavioral · Dietary Supplement
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
40 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 22, 2021 · Synced Sep 26, 2026, 11:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Small Bowel Microbiota Characterization in Healthy Individuals Before and After Consumption of a Western Diet

NCT03266536
View directory record Official record
Conditions
Small Intestine Bacteria
Interventions
Western diet
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 3, 2022 · Synced Sep 26, 2026, 11:56 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Food Effects on Bioavailability of MDMA in Healthy Volunteers

NCT05147402
View directory record Official record
Conditions
Pharmacokinetics
Interventions
midomafetamine
Drug
Lead sponsor
Resilient Pharmaceuticals
Industry
Eligibility
18 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 29, 2024 · Synced Sep 26, 2026, 11:56 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study to Learn About How Food and Esomeprazole Affect the Level of BAY2927088 in the Blood When Taken Together in Healthy Participants

NCT06378658
View directory record Official record
Conditions
Advanced Non-small Cell Lung Cancer, EGFR Mutation, HER2 Mutation, Healthy Volunteers
Interventions
BAY2927088, Esomeprazole, Food
Drug · Other
Lead sponsor
Bayer
Industry
Eligibility
18 Years to 55 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 4, 2024 · Synced Sep 26, 2026, 11:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Anti-inflammatory Effects of Fiber

NCT02781350
View directory record Official record
Conditions
Postprandial Inflammation
Interventions
HFHC meal, HFHC MEAL plus Fiber
Other · Dietary Supplement
Lead sponsor
University at Buffalo
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated May 24, 2016 · Synced Sep 26, 2026, 11:56 PM EDT