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Showing 1–24 of 210 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: High Intensity Interval training Clear all
Completed Not applicable Interventional Accepts healthy volunteers

An Exercise Intervention to Improve Overall Brain Health

NCT06035094
View directory record Official record
Conditions
Brain Care Score, Exercise, Hypertension, BMI
Interventions
Exercise Intervention to improve overall Brain Health
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
35 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Sep 10, 2026, 1:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Ethnicity on Changes in VO2max and Cardiac Output in Response to Short-Term High Intensity Interval Training

NCT04449016
View directory record Official record
Conditions
Improved VO2max and Cardiac Output in Response to Training
Interventions
High intensity interval training
Other
Lead sponsor
California State University, San Marcos
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
San Marcos, California
Source: ClinicalTrials.gov public record
Updated Jun 25, 2020 · Synced Sep 10, 2026, 1:26 AM EDT
Recruiting Not applicable Interventional

High-Intensity Exercise and High-Fiber Diet for Immunotherapy Outcomes in Melanoma Patients: The DUO Trial

NCT06298734
View directory record Official record
Conditions
Melanoma (Skin), Skin Cancer, Advanced Melanoma
Interventions
Exercise Program, Diet Program
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 10, 2026, 1:26 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Acute Effect of Exercise on Vascular Function

NCT02408614
View directory record Official record
Conditions
Aging
Interventions
Slow-paced walking, Moderate-paced walking, Interval Training, Treadmill
Other · Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 79 Years
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 24, 2019 · Synced Sep 10, 2026, 1:26 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Acute Effects of High-intensity Interval Training With Mindfulness-based Recovery on Executive Function in Children

NCT06270589
View directory record Official record
Conditions
Healthy Volunteers
Interventions
MF-HIIT, MF-only, HIIT-only, Sitting rest
Behavioral
Lead sponsor
Purdue University
Other
Eligibility
10 Years to 12 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Sep 10, 2026, 1:26 AM EDT
Completed Not applicable Interventional Results available

High-Intensity Interval Training to Improve Symptoms of Deployment-Related Respiratory Disease

NCT05849168
View directory record Official record
Conditions
Occupational Exposure
Interventions
Exercise training
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Sep 10, 2026, 1:26 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

High-Intensity Interval Exercise in Young Adult Survivors of Pediatric Brain Tumors: A Pilot Feasibility Study

NCT05740839
View directory record Official record
Conditions
Pediatric Brain Tumor
Interventions
HIIT Exercise Program, Control Group
Behavioral
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years to 45 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Sep 10, 2026, 1:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exercise, Cognitive Function and Neuroplasticity in Healthy Adults

NCT02994134
View directory record Official record
Conditions
Sedentary Lifestyle
Interventions
Moderate intensity exercise., High intensity exercise.
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 70 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Dec 7, 2021 · Synced Sep 10, 2026, 1:26 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Breaking Sitting with High-intensity Interval Training for Brain Health

NCT06243016
View directory record Official record
Conditions
Aging
Interventions
High-Intensity Interval Training (HIIT) Breaks to Sitting, Light-Intensity Interval Training (LIIT) Breaks to Sitting
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
40 Years to 75 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 6, 2025 · Synced Sep 10, 2026, 1:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Aerobic Interval Training on Cardiovascular Function in Aging

NCT01883271
View directory record Official record
Conditions
Aging
Interventions
High intensity aerobic interval training, Continuous moderate intensity exercise
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 79 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2019
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 24, 2019 · Synced Sep 10, 2026, 1:26 AM EDT
Active, not recruiting Not applicable Interventional

Improving Cognitive Function Through High-intensity Interval Training in Breast Cancer Patients Undergoing Chemotherapy

NCT04724499
View directory record Official record
Conditions
Breast Cancer, Chemotherapy Effect, Exercise Therapy, Cognitive Change
Interventions
High-Intensity Intervals Training, Attention Control
Behavioral · Other
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 10, 2026, 1:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of β-Hydroxy-β-methylbutyrate Free Acid and High-Intensity Interval Training

NCT01941368
View directory record Official record
Conditions
Exercise
Interventions
Placebo, HMB-FA, High Intensity Interval Training
Dietary Supplement · Procedure
Lead sponsor
Metabolic Technologies Inc.
Industry
Eligibility
18 Years to 35 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Mar 16, 2014 · Synced Sep 10, 2026, 1:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Body Weight-Based Interval Training in Sedentary Overweight and Obese Adults

NCT03524521
View directory record Official record
Conditions
Body Weight Changes, Overweight and Obesity, Physical Activity
Interventions
Interval Training, Standard of Care
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 10, 2021 · Synced Sep 10, 2026, 1:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

High-Intensity Interval Training and Performance

NCT05821504
View directory record Official record
Conditions
Healthy
Interventions
High-Intensity Interval Training
Behavioral
Lead sponsor
Kennesaw State University
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Kennesaw, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 12, 2023 · Synced Sep 10, 2026, 1:26 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Kettlebell Training Measured Across Power and Performance

NCT02731625
View directory record Official record
Conditions
Athletic Performance, Weight Lifting
Interventions
Kettlebell training, Army Physical Readiness Training
Other
Lead sponsor
Keller Army Community Hospital
Federal
Eligibility
17 Years to 27 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
West Point, New York
Source: ClinicalTrials.gov public record
Updated Mar 12, 2017 · Synced Sep 10, 2026, 1:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Comparison of High-intensity Interval Training Protocols on Health and Fitness

NCT03093441
View directory record Official record
Conditions
Healthy
Interventions
Multimodal High-Intensity Interval Training Intervention
Other
Lead sponsor
Oakland University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Rochester, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 12, 2019 · Synced Sep 10, 2026, 1:26 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Nicotinamide Mononucleotide Supplementation for Exercise Tolerance Improvement in Healthy Older Adults

NCT07144527
View directory record Official record
Conditions
Aging, Frailty, Exercise Tolerance, Healthy Male and Female Subjects
Interventions
NMN, betaine, low-dose hydrogen peroxide (EGA), Nicotinamide Mononucleotide (NMN), Placebo
Dietary Supplement
Lead sponsor
Scott Silveira
Other
Eligibility
60 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Beverly Hills, California
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Sep 10, 2026, 1:26 AM EDT
Completed Not applicable Interventional

Exercise Preconditioning and Breast Cancer Cardiotoxicity

NCT02842658
View directory record Official record
Conditions
Breast Cancer
Interventions
A high-intensity interval exercise group, An Attention-Control Group
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years to 70 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 23, 2020 · Synced Sep 10, 2026, 1:26 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effect of High-Intensity Exercise to Attenuate Cognitive Function Limitations and Train Exercise Habits in Older People Living With HIV

NCT06013579
View directory record Official record
Conditions
HIV Infections, Cognitive Impairment
Interventions
Phase 1 Gym Exercise HIIT, Phase 1 Gym Exercise CME, Phase 2 Home Exercise Coaching Text Messages, Phase 2 Home Exercise Control Text Messages
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
50 Years to 80 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
3
States / cities
Birmingham, Alabama • Aurora, Colorado • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 7, 2025 · Synced Sep 10, 2026, 1:26 AM EDT
Completed Not applicable Interventional Results available

Effects of a Walking Program and Inspiratory Muscle Training in Individuals With Chronic Heart Failure

NCT01560871
View directory record Official record
Conditions
Heart Failure NYHA Class II, Heart Failure NYHA Class III
Interventions
High-intensity IMT plus walking, Low-intensity IMT plus walking
Behavioral
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 90 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
2
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 2, 2020 · Synced Sep 10, 2026, 1:26 AM EDT
Completed Not applicable Interventional

Home-based HIIT to Improve CRC Survivorship: Feasibility and Relationship With Novel Surrogate Biomarkers of CRC Recurrence

NCT04080414
View directory record Official record
Conditions
Colorectal Cancer, Colorectal Neoplasms, Colorectal Carcinoma, Colonic Neoplasms, Colonic Cancer, Rectal Neoplasms, Rectal Cancer
Interventions
Home-based high-intensity interval training, Home-based moderate-intensity continuous exercise
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
19 Years to 75 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
2
States / cities
Murray, Utah • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 21, 2023 · Synced Sep 10, 2026, 1:26 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

High-Intensity Functional Training (HIFT) vs Moderate-Intensity Continuous Training (MICT) in College Students

NCT07745270
View directory record Official record
Conditions
Exercise
Interventions
High-Intensity Functional Training (HIFT), Moderate-Intensity Continuous Training (MICT)
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 35 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Sep 10, 2026, 1:26 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Examining the Impact of Exercise Training on Vascular Dysfunction in Individuals With Mental Health Disorders - Study 2

NCT04922762
View directory record Official record
Conditions
Peripheral Vascular Diseases
Interventions
Moderate Intensity, Normal Volume Exercise Training, High Intensity, Normal Volume Exercise Training, Moderate Intensity, High Volume Exercise Training
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 35 Years
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 16, 2025 · Synced Sep 10, 2026, 1:26 AM EDT
Recruiting Not applicable Interventional

Cortical Priming to Optimize Gait Rehabilitation in Stroke: a Renewal

NCT04477330
View directory record Official record
Conditions
Stroke
Interventions
Transcranial direct current stimulation (tDCS), Ankle motor training, High intensity interval speed based treadmill training (HIISTT)
Other · Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Sep 10, 2026, 1:26 AM EDT