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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Hyaluronic Acid Injection Clear all
Completed No phase listed Observational Accepts healthy volunteers

Retrospective Evaluation of Combination Treatment With the Ulthera System

NCT02444169
View directory record Official record
Conditions
Skin Laxity
Interventions
Ultherapy, Incobotulinumtoxin A, Radiesse, Belotero Balance
Device · Drug
Lead sponsor
Ulthera, Inc
Industry
Eligibility
25 Years to 70 Years
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
5
States / cities
Laguna Beach, California • San Diego, California • Coral Gables, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 23, 2017 · Synced Sep 26, 2026, 10:22 PM EDT
Completed Not applicable Interventional Results available

JUVEDERM® Ultra XC vs. Belotero Balance® for Perioral Lines

NCT01970397
View directory record Official record
Conditions
Patients With Moderate to Severe Perioral Lines
Interventions
JUVEDERM® Ultra XC, Belotero Balance®
Device
Lead sponsor
Allergan
Industry
Eligibility
35 Years and older
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 15, 2019 · Synced Sep 26, 2026, 10:22 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Combination Facial Aesthetic Treatment in Millennials

NCT04755595
View directory record Official record
Conditions
Dermatological Non-Disease
Interventions
Botox Cosmetic Injectable Product, Juvéderm Voluma XC, Juvéderm Volbella XC
Drug · Device
Lead sponsor
State University of New York - Downstate Medical Center
Other
Eligibility
24 Years to 40 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Jan 13, 2025 · Synced Sep 26, 2026, 10:22 PM EDT
Completed Phase 1 Interventional

Study to Evaluate the Safety and Preliminary Efficacy of IDCT, a Treatment for Symptomatic Lumbar Intervertebral Disc Degeneration

NCT03347708
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
IDCT, Saline Solution, Sodium Hyaluronate
Biological · Drug
Lead sponsor
DiscGenics, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
14
States / cities
Birmingham, Alabama • Los Angeles, California • San Diego, California + 11 more
Source: ClinicalTrials.gov public record
Updated Jan 24, 2023 · Synced Sep 26, 2026, 10:22 PM EDT
Terminated Phase 4 Interventional Results available

Knee Injection RCT

NCT03694821
View directory record Official record
Conditions
Osteoarthritis
Interventions
Ketorolac Tromethamine Injection, Methylprednisolone Acetate Injection, Hylan G-F 20
Drug
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 17, 2020 · Synced Sep 26, 2026, 10:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Jowl Improvement With Injectable Fillers

NCT04389866
View directory record Official record
Conditions
Jowls
Interventions
JUVÉDERM VOLUMA™ XC
Device
Lead sponsor
Advanced Dermatology
Other
Eligibility
35 Years to 75 Years · Female only
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Lincolnshire, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 14, 2024 · Synced Sep 26, 2026, 10:22 PM EDT
Completed Not applicable Interventional Results available

Cooled Radiofrequency vs. Hyaluronic Acid to Manage Knee Pain

NCT03381248
View directory record Official record
Conditions
Osteoarthritis of the Knee
Interventions
Cooled Radiofrequency, Hyaluronic Acid Injection, Crossover from Hyaluronic Acid Injection to Cooled Radiofrequency
Device · Other
Lead sponsor
Avanos Medical
Other
Eligibility
21 Years and older
Enrollment
177 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
10
States / cities
Coeur d'Alene, Idaho • New Orleans, Louisiana • Rochester, Minnesota + 7 more
Source: ClinicalTrials.gov public record
Updated Oct 9, 2023 · Synced Sep 26, 2026, 10:22 PM EDT
Recruiting Phase 2 Interventional

Intra-articular Platelet-Rich Plasma Compared With Viscosupplementation in the Treatment of Knee Osteoarthritis

NCT03491761
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
PRP Treatment, HA Treatment
Biological
Lead sponsor
Endeavor Health
Other
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
1
States / cities
Skokie, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 27, 2024 · Synced Sep 26, 2026, 10:22 PM EDT
Completed Phase 4 Interventional

TREAD-20 Extension - Treatment of Knee Pain Due to Osteoarthritis

NCT00830830
View directory record Official record
Conditions
Osteoarthritis
Interventions
Hyalgan (sodium hyaluronate)
Drug
Lead sponsor
Sanofi
Industry
Eligibility
40 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Bridgewater, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 18, 2009 · Synced Sep 26, 2026, 10:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Shafer Width and Girth: The Use of Injectable Fillers for Penile Enhancement

NCT04755634
View directory record Official record
Conditions
Micropenis
Interventions
Hyaluronic Acid
Device
Lead sponsor
Shafer Clinic Fifth Avenue
Network
Eligibility
21 Years to 65 Years · Male only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 26, 2026, 10:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

RHA® 4 NLF Cannula

NCT04754646
View directory record Official record
Conditions
Wrinkle, Nasolabial Fold, Aging
Interventions
Split-face injection of RHA® 4 with a cannula into a single NLF., Split-face injection of RHA® 4 with a needle (TSK 27G x ½") into the contralateral NLF.
Device
Lead sponsor
Teoxane SA
Industry
Eligibility
22 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
4
States / cities
Encinitas, California • West Palm Beach, Florida • Chapel Hill, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 8, 2023 · Synced Sep 26, 2026, 10:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Perioral Rejuvenation and Upper Lip Enhancement

NCT03273543
View directory record Official record
Conditions
Perioral Rejuvenation, Upper Lip Projection
Interventions
Restylane® Defyne
Device
Lead sponsor
DeNova Research
Other
Eligibility
21 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 7, 2020 · Synced Sep 26, 2026, 10:22 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Ethnic Lip Augmentation With Hyaluronic Acid Filler

NCT05730543
View directory record Official record
Conditions
Lip Augmentation, Lip Fullness
Interventions
Volbella or Juvederm Ultra XC filler
Drug
Lead sponsor
DeNova Research
Other
Eligibility
21 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 6, 2023 · Synced Sep 26, 2026, 10:22 PM EDT
Completed Phase 4 Interventional

Comparative Study of Reconstituted JUVÉDERM® Ultra vs COSMODERM® 1 for Lip and Cheek Lines, Folds or Wrinkles

NCT01212809
View directory record Official record
Conditions
Intrinsic Aging of Skin
Interventions
Juvéderm Ultra, Cosmoderm 1
Device
Lead sponsor
Steven Fagien
Other
Eligibility
25 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Boca Raton, Florida
Source: ClinicalTrials.gov public record
Updated Sep 11, 2011 · Synced Sep 26, 2026, 10:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Assess the Impact of Lip Rejuvenation on Projected First Impressions and Mood Perceptions

NCT03241862
View directory record Official record
Conditions
Lip Rejuvenation
Interventions
Restylane® Silk
Device
Lead sponsor
DeNova Research
Other
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 3, 2020 · Synced Sep 26, 2026, 10:22 PM EDT
Completed Phase 4 Interventional Results available

Study to Evaluate Safety and Effectiveness of AdvaCoat Sinus Gel

NCT00554190
View directory record Official record
Conditions
Ethmoid Sinusitis, Rhinosinusitis
Interventions
AdvaCoat sinus gel, Merogel Injectable
Device
Lead sponsor
Carbylan Therapeutics, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
4
States / cities
Birmingham, Alabama • San Francisco, California • Chicago, Illinois + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 22, 2009 · Synced Sep 26, 2026, 10:22 PM EDT
Completed Phase 3 Interventional Results available

Placebo-controlled Study to Evaluate Rexlemestrocel-L Alone or Combined With Hyaluronic Acid in Participants With Chronic Low Back Pain

NCT02412735
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
Rexlemestrocel-L, Rexlemestrocel-L + HA Mixture, Placebo
Drug
Lead sponsor
Mesoblast, Ltd.
Industry
Eligibility
18 Years and older
Enrollment
404 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
47
States / cities
Birmingham, Alabama • Huntsville, Alabama • Scottsdale, Arizona + 42 more
Source: ClinicalTrials.gov public record
Updated Oct 18, 2022 · Synced Sep 26, 2026, 10:22 PM EDT
Terminated Phase 1 Interventional

Pilot Study of Therapy With Hylan G-F 20 Exercise Capacity

NCT01810848
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Hylan G-F 20, Control
Device · Other
Lead sponsor
OhioHealth
Other
Eligibility
40 Years to 70 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 28, 2016 · Synced Sep 26, 2026, 10:22 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Restylane Silk Microinjections to Cheeks

NCT03742479
View directory record Official record
Conditions
Wrinkle
Interventions
Restylane® Silk
Device
Lead sponsor
Goldman, Butterwick, Fitzpatrick and Groff
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 2, 2019 · Synced Sep 26, 2026, 10:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Study of the Efficacy and Safety of EUFLEXXA™ for Treatment of Painful Osteoarthritis of the Knee

NCT00379236
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
EUFLEXXA™, placebo
Device
Lead sponsor
Ferring Pharmaceuticals
Industry
Eligibility
40 Years and older
Enrollment
588 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 27, 2011 · Synced Sep 26, 2026, 10:22 PM EDT
Completed Phase 4 Interventional Results available

Patient Satisfaction Study of Combined Facial Treatment With BOTOX® Cosmetic, JUVÉDERM® and LATISSE® (HARMONY Study)

NCT02176356
View directory record Official record
Conditions
Facial Rhytides, Crow's Feet Lines, Glabellar Lines, Nasolabial Fold
Interventions
onabotulinumtoxinA, bimatoprost ophthalmic solution 0.03%, JUVÉDERM® ULTRA XC, JUVÉDERM® ULTRA PLUS XC, JUVÉDERM® VOLUMA® XC
Biological · Drug · Device
Lead sponsor
Allergan
Industry
Eligibility
35 Years to 65 Years
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 8, 2019 · Synced Sep 26, 2026, 10:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effectiveness and Safety of Restylane Lyft With Lidocaine in the Dorsal Hand

NCT02650921
View directory record Official record
Conditions
Volume Deficit in the Hand
Interventions
Restylane Lyft with Lidocaine
Device
Lead sponsor
Galderma R&D
Industry
Eligibility
22 Years and older
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
7
States / cities
Vista, California • Boulder, Colorado • Englewood, Colorado + 4 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2022 · Synced Sep 26, 2026, 10:22 PM EDT
Completed Not applicable Interventional

2 Weekly Intra-articular Hyaluronan Knee Injections, Given 1 wk. Apart, of HYMOVIS Combined With Physical Exercise Program (PEP) Compared to PEP Alone, in Relatively Young, Active Population of Subjects With Patellofemoral Osteoarthritis (PFOA) and/or Tibiofemoral Osteoarthritis (TFOA)

NCT03281837
View directory record Official record
Conditions
Osteoarthritis, Knee, Knee Osteoarthritis, Patellofemoral Osteoarthritis
Interventions
HYMOVIS plus Physical Exercise Program (PEP), Physical Exercise Program (PEP) alone
Device · Other
Lead sponsor
Fidia Pharma USA Inc.
Industry
Eligibility
21 Years to 60 Years
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
10
States / cities
Tucson, Arizona • Encinitas, California • Los Angeles, California + 5 more
Source: ClinicalTrials.gov public record
Updated Jul 20, 2020 · Synced Sep 26, 2026, 10:22 PM EDT
Completed Phase 1 Interventional

Cross-linked Hyaluronan Gel Reduces Rectal Toxicity Due to Radiation Therapy for Prostate Cancer

NCT00882232
View directory record Official record
Conditions
Prostate Cancer
Interventions
Cross-linked hyaluronan gel
Device
Lead sponsor
Cancer Center of Irvine
Other
Eligibility
18 Years and older · Male only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Feb 14, 2013 · Synced Sep 26, 2026, 10:22 PM EDT