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ClinicalTrials.gov public records Last synced Nov 12, 2026, 4:47 AM EST

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Showing 1–24 of 120 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Hyperbaric Oxygen Therapy Clear all

Conditions: Post-Concussion Syndrome
Interventions: Hyperbaric Oxygen Treatment, Placebo gas; Device · Other
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: COVID-19
Interventions: hyperbaric oxygen therapy (HBOT); Device
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020
U.S. locations: 1
States / cities: Mineola, New York

Conditions: Brain Injury, Sequelae, Stroke, Anoxia, Trauma
Interventions: Magnetic Resonance Imaging, Computed Tomography Angiography; Procedure
Lead sponsor: Intermountain Health Care, Inc.; Other
Eligibility: 18 Years to 80 Years
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Mild Traumatic Brain Injury, Post-Concussive Syndrome
Interventions: Hyperbaric Oxygen Therapy; Procedure
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 19 Years to 60 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 3
States / cities: Portsmouth, Virginia • Richmond, Virginia

Conditions: Mild Traumatic Brain Injury, Hyperbaric Oxygen Therapy, Depression
Interventions: Oxygen 100 % Gas for Inhalation, Hyperbaric Oxygen Therapy Chamber; Drug · Device
Lead sponsor: Nova Southeastern University; Other
Eligibility: 18 Years to 70 Years · Male only
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Fort Lauderdale, Florida

Conditions: Brain Injury, Chronic
Interventions: Hyperbaric Oxygen, Minimal pressure air; Combination Product
Lead sponsor: Lindell Weaver; Other
Eligibility: 18 Years to 70 Years
Enrollment: 49 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 2
States / cities: Murray, Utah • Salt Lake City, Utah

Conditions: Traumatic Brain Injury, PTSD - Post Traumatic Stress Disorder, Anxiety, Depression, Post Concussion Symptoms
Interventions: Hyperbaric Oxygen Therapy (HBOT); Drug
Lead sponsor: Summit Hyperbarics and Wellness; Other
Eligibility: 18 Years to 75 Years
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Boise, Idaho

Conditions: Exercise Performance
Interventions: Hyperbaric chamber, Ambient pressure; Other
Lead sponsor: Intermountain Health Care, Inc.; Other
Eligibility: 18 Years to 40 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Murray, Utah

Conditions: Amputation; Postoperative, Sequelae
Interventions: Hyperbaric Oxygen; Drug
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Brain and Central Nervous System Tumors, Cognitive/Functional Effects, Radiation Toxicity
Interventions: dexamethasone, hyperbaric oxygen, cognitive assessment, magnetic resonance imaging, positron emission tomography, quality-of-life assessment; Drug · Procedure
Lead sponsor: Barrett Cancer Center; Other
Eligibility: Not listed
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2005
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Breast Cancer
Interventions: Hyperbaric Oxygen Therapy, Trental Pill, Vitamin E; Procedure · Drug · Dietary Supplement
Lead sponsor: Legacy Health System; Other
Eligibility: 18 Years and older · Female only
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Carbon Monoxide Poisoning
Interventions: Hyperbaric Oxygen (HBO2) - 3 sessions, Hyperbaric Oxygen (HBO2) - 1 session; Combination Product
Lead sponsor: Intermountain Health Care, Inc.; Other
Eligibility: 18 Years to 79 Years
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2017
U.S. locations: 2
States / cities: Salt Lake City, Utah

Conditions: Autism, Oxidative Stress, Inflammation
Interventions: Hyperbaric Oxygen Therapy; Drug
Lead sponsor: International Hyperbarics Association; Other
Eligibility: 2 Years to 18 Years
Enrollment: 18 participants
U.S. locations: 1
States / cities: Arrington, Virginia

Conditions: Ulcerative Colitis
Interventions: Hyperbaric Oxygen Therapy, Sham Hyperbaric Air; Device · Other
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 85 Years
Enrollment: 126 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 13
States / cities: Birmingham, Alabama • Los Angeles, California • Miami, Florida + 9 more

Conditions: Ischemic Cerebrovascular Accident
Interventions: hyperbaric oxygen chamber; Other
Lead sponsor: John Davidson; Other
Eligibility: 50 Years to 80 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Chesterfield, Missouri

Conditions: Wounds and Injuries
Interventions: Not listed
Lead sponsor: CW Optics, Inc.; Industry
Eligibility: 21 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Winchester, Virginia

Conditions: Postoperative Complications, Hip Fracture, Delirium
Interventions: General endotracheal anesthesia, Regional (spinal) Anesthesia; Other
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Osteoradionecrosis of the Jaw, Xerostomia
Interventions: Not listed
Lead sponsor: Loma Linda University; Other
Eligibility: 18 Years to 100 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2022
U.S. locations: 1
States / cities: Loma Linda, California

Conditions: Impotence, Prostatic Neoplasms
Interventions: Sildenafil therapy plus post-NSRRP HBO2T, Sildenafil therapy plus sham post-NSRRP HBO2T; Drug
Lead sponsor: Hartford Hospital; Other
Eligibility: 40 Years to 65 Years · Male only
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2021
U.S. locations: 1
States / cities: Hartford, Connecticut

Conditions: AML, NHL, Hodgkin Disease, All, Myelodysplastic Syndrome
Interventions: Hyperbaric oxygen; Drug
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years to 70 Years
Enrollment: 64 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2027
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Ear Barotrauma, Middle Ear Disease, Ear Diseases, Pressure Injury, Eustachian Tube Dysfunction, Middle Ear; Injury, Middle Ear Barotrauma
Interventions: Compression Profile/Schedule: 15 minute Non-Linear compression from start of the daily treatment until treatment pressure is reached (45 fsw), Compression Profile/Schedule: 15 minute Linear compression from start of the daily treatment until treatment pressure is reached (45 fsw); Procedure
Lead sponsor: Northwell Health; Other
Eligibility: Not listed
Enrollment: 1,553 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Sleepy Hollow, New York

Conditions: Autism, Oxidative Stress
Interventions: Hyperbaric Oxygen; Other
Lead sponsor: The International Child Development Resource Center; Other
Eligibility: 5 Years to 12 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2006
U.S. locations: 1
States / cities: Melbourne, Florida

Conditions: Traumatic Brain Injury (TBI) Patients, Post Concussive Symptoms, PTSD
Interventions: Hyperbaric Oxygen Therapy (HBOT); Drug
Lead sponsor: Summit Hyperbarics and Wellness; Other
Eligibility: 18 Years to 75 Years
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Boise, Idaho

Conditions: Diabetes Mellitus
Interventions: HBOT intervention, Sham intervention; Device
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 65 Years and older
Enrollment: 155 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2024
U.S. locations: 2
States / cities: New York, New York • Madison, Wisconsin

Search by objective public record fields.

Hyperbaric Oxygen Therapy for Post-Concussion Syndrome

Hyperbaric Oxygen for COVID-19 Patients

Functional and Anatomical Magnetic Resonance Imaging (MRI) of Chronic Brain Injury and Hyperbaric Oxygen (HBO2) Study Subjects

Hyperbaric Oxygen Therapy (HBO2T) for Post-Concussive Symptoms (PSC) After Mild Traumatic Brain Injury (mTBI)

Treatment of U.S. Veterans With Mild Traumatic Brain Injury With Hyperbaric Oxygen Therapy

Hyperbaric Oxygen for Traumatic and Non-traumatic Brain Injury

HBOT Effects on First Responders' Cognition and Well-Being

Effects of High-Intensity Interval Training (HIT) While in a Hyperoxic-Hyperbaric Environment on Exercise Performance

Hyperbaric Oxygen and Outcome After Below Knee Amputations

Hyperbaric Oxygen Therapy in Treating Patients With Radiation Necrosis of the Brain

Acute Post-Radiation Hyperbaric Oxygen (HBO2) for Breast Cancer Patients Who Have Recently Completed Radiation Therapy

One vs. Three Hyperbaric Oxygen Treatments for Acute Carbon Monoxide Poisoning

Effects of Hyperbaric Oxygen Therapy in Autistic Children: A Pilot Study

Hyperbaric Oxygen Therapy for Ulcerative Colitis (HBOT-UC)

The Use of Hyperbaric Oxygen to Increase the Blood Supply in the Injured, But Still Alive Tissue, Around an Old Stroke

Laser Speckle Imaging for Wound Perfusion Monitoring (WoundImager)

A Trial To Assess Risk of Delirium in Older Adults Undergoing Hip Fracture Surgery With Spinal or General Anesthesia

Saliva, Hyperbaric Oxygen Therapy, & Gland Function: A Prospective Study

Can Hyperbaric Oxygen Improve Erectile Function Following Surgery for Prostate Cancer

A Randomized Phase II Study of Hyperbaric Oxygen in Improving Engraftment in Umbilical Cord Blood Stem Cell Transplant

Effect of Rate (Slope) of Compression on the Incidence of Symptomatic ETD and MEB: a Phase III Prospective Study.

Effect of Hyperbaric Therapy on Markers of Oxidative Stress in Children With Autism

Hyperbaric Oxygen Therapy for Veterans With TBI and PCS: A Biomarker Study

Hyperbaric Oxygen Therapy for Cognition in Diabetic Elderly at High Dementia Risk