- Conditions
- Healthy
- Interventions
- Tolvaptan, Hypertonic saline infusion
- Drug
- Lead sponsor
- Northwestern University
- Other
- Eligibility
- 21 Years to 55 Years · Male only
- Enrollment
- 17 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013 – 2016
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–12
of 12
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Salt-Sensitivity of Blood Pressure
- Interventions
- Furosemide (Diuretic), Hypertonic Saline Infusion
- Drug · Other
- Lead sponsor
- University of Delaware
- Other
- Eligibility
- 40 Years to 60 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2028
- U.S. locations
- 1
- States / cities
- Newark, Delaware
- Conditions
- Congestive Heart Failure, Renal Insufficiency
- Interventions
- Hypertonic saline, then oral sodium chloride, Normal saline, then oral placebo capsule
- Drug
- Lead sponsor
- Barnes-Jewish Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 11 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2008
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Insulin Resistance
- Interventions
- Hypertonic Saline (3% NaCl), Isotonic Saline (0.9% NaCl)
- Other
- Lead sponsor
- University of Arkansas, Fayetteville
- Other
- Eligibility
- 30 Years to 50 Years · Male only
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Fayetteville, Arkansas
- Conditions
- Salt Sensitivity of Blood Pressure
- Interventions
- Hypertonic Saline with furosemide, Hypertonic Saline without furosemide
- Other
- Lead sponsor
- University of Delaware
- Other
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 29 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2025
- U.S. locations
- 1
- States / cities
- Newark, Delaware
- Conditions
- BK Virus (Nephropathy)
- Interventions
- Cidofovir, Placebo
- Drug
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Eligibility
- 18 Years and older
- Enrollment
- 22 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2011
- U.S. locations
- 12
- States / cities
- Birmingham, Alabama • San Francisco, California • Aurora, Colorado + 7 more
- Conditions
- Hypertension
- Interventions
- DEFINITY® infusion, Human Recombinant Regular Insulin infusion, Dextrose infusion, Flow mediated vasodilation, Endothelial cell collection, Microvascular perfusion assessment using Definity, Microneurography
- Drug · Procedure
- Lead sponsor
- Wanpen Vongpatanasin
- Other
- Eligibility
- 18 Years to 75 Years
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010 – 2025
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Cerebral Edema, Saline Solution, Hypertonic
- Interventions
- 3% Sodium Chloride, 23.4% Sodium Chloride, 8.4% Sodium Bicarbonate
- Drug
- Lead sponsor
- Stanford University
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2020
- U.S. locations
- 1
- States / cities
- Stanford, California
- Conditions
- Water Stress, Body Water Dehydration
- Interventions
- Hypertonic Saline, Normal Saline
- Other
- Lead sponsor
- University of North Carolina, Greensboro
- Other
- Eligibility
- 18 Years to 35 Years
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Greensboro, North Carolina
- Conditions
- Traumatic Brain Injury, Elevated Intracranial Pressure
- Interventions
- Mannitol, Hypertonic Saline
- Drug
- Lead sponsor
- University of Cincinnati
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 5 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010
- U.S. locations
- 1
- States / cities
- Cincinnati, Ohio
- Conditions
- Obesity
- Interventions
- Hypertonic saline infusion, Water deprivation
- Other
- Lead sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- NIH
- Eligibility
- 18 Years to 50 Years · Male only
- Enrollment
- 75 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2019
- U.S. locations
- 1
- States / cities
- Phoenix, Arizona
- Conditions
- Hemodialysis Complication, Hemodynamic Instability
- Interventions
- Mannitol, 0.9% saline
- Drug
- Lead sponsor
- Brigham and Women's Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 31 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts