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ClinicalTrials.gov public records Last synced Oct 23, 2026, 1:24 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 481–504 of 8,263 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: IMPROVED Clear all
Completed No phase listed Observational Accepts healthy volunteers

Specifying Interventions From the Sickle Cell Disease Implementation Consortium (SCDIC)

NCT03380351
View directory record Official record
Conditions
Anemia, Sickle Cell
Interventions
SCDIC interventions
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 8, 2024 · Synced Oct 23, 2026, 1:24 PM EDT
Enrolling by invitation Early Phase 1 Interventional Accepts healthy volunteers

Effectiveness of Microdosed GLP-1 in Improving Health, Quality of Life, and Longevity Measures

NCT07092605
View directory record Official record
Conditions
Longevity, Quality of Life, Mood, Inflammation, Immune Health, Pain Management, Weight Management, Alertness
Interventions
GLP-1, Placebo
Drug
Lead sponsor
AgelessRx
Industry
Eligibility
18 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 30, 2025 · Synced Oct 23, 2026, 1:24 PM EDT
Completed Not applicable Interventional Results available

Predictors of Speech Ability in Down Syndrome

NCT05016037
View directory record Official record
Conditions
Speech Intelligibility Intervention in Down Syndrome
Interventions
Lexically based speech recast
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
4 Years to 17 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 3, 2025 · Synced Oct 23, 2026, 1:24 PM EDT
Completed Not applicable Interventional

Study to Evaluate Efficacy and Tolerability of Two Topical Regimens in Subjects With Moderate to Severe Facial Photodamage Who Have Received Cosmetic Injections

NCT03559972
View directory record Official record
Conditions
Facial Photodamage
Interventions
on-label facial injection
Other
Lead sponsor
Allergan
Industry
Eligibility
30 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
2
States / cities
San Diego, California • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 30, 2019 · Synced Oct 23, 2026, 1:24 PM EDT
Active, not recruiting No phase listed Observational

Quality of Life in Pre and Post Renal Transplant in Hispanic and Non-Hispanic Recipients

NCT00856895
View directory record Official record
Conditions
Transplant; Failure, Kidney
Interventions
Not listed
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
1,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 29, 2025 · Synced Oct 23, 2026, 1:24 PM EDT
Completed Not applicable Interventional Results available

Reduced Opioid Analgesic Requirements Via Improved Endogenous Opioid Function

NCT02469077
View directory record Official record
Conditions
Chronic Pain
Interventions
6 week aerobic exercise intervention, Placebo, Morphine, naloxone
Behavioral · Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 55 Years
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
2
States / cities
Chicago, Illinois • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 23, 2020 · Synced Oct 23, 2026, 1:24 PM EDT
Completed Not applicable Interventional

Risks and Benefits of Naloxone Prescribing

NCT02535494
View directory record Official record
Conditions
Opioid Overdose
Interventions
Extensive training
Other
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
21 Years to 65 Years
Enrollment
405 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 2, 2022 · Synced Oct 23, 2026, 1:24 PM EDT
Recruiting Not applicable Interventional

TURN-IT FOG: Improving Turning and Freezing of Gait in People With PD

NCT06815302
View directory record Official record
Conditions
Parkinson Disease, Freezing of Gait Symptoms in Parkinson Disease
Interventions
Experimental intervention, Active intervention
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
50 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Tempe, Arizona • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 28, 2025 · Synced Oct 23, 2026, 1:24 PM EDT
Terminated Not applicable Interventional

A Feasibility Trial of a Web Based App Intervention in Hormone Positive Breast Cancer Patients to Improve Adherence to Endocrine Therapy

NCT05488145
View directory record Official record
Conditions
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, HER2-Negative Breast Carcinoma, Hormone Receptor-Positive Breast Carcinoma
Interventions
Best Practice, Internet-Based Intervention, Questionnaire Administration, Survey Administration
Other
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
4
States / cities
Atlanta, Georgia • Johns Creek, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 17, 2026 · Synced Oct 23, 2026, 1:24 PM EDT
Completed Not applicable Interventional Results available

Aerobic Exercise for Remyelination in Multiple Sclerosis

NCT04539002
View directory record Official record
Conditions
Multiple Sclerosis, Sclerosis, Demyelinating Diseases, Autoimmune Diseases of the Nervous System, Nervous System Diseases, Demyelinating Autoimmune Diseases, CNS, Exercise
Interventions
Aerobic exercise, Education Group Control
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 64 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Oct 23, 2026, 1:24 PM EDT
Completed Not applicable Interventional

Peau o le Vasa: Analysis of the Efficacy and Feasibility of the PILI Lifestyle Program (PLP) + Social Determinants of Health (SDOH) Intervention and Adaptation of SDOH Measures Pilot Study

NCT06471595
View directory record Official record
Conditions
Weight Loss Trial, Cardiometabolic Syndrome, Hypertension, Dyslipidemia, Pre-diabetes, Type 2 Diabetes Mellitus
Interventions
Partnership for Improving Lifestyle Intervention (PILI) Lifestyle Program + Social Determinants of Health (SDOH) Component
Behavioral
Lead sponsor
University of Hawaii
Other
Eligibility
18 Years and older
Enrollment
242 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
4
States / cities
Fayetteville, Arkansas • Springdale, Arkansas • Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Oct 23, 2026, 1:24 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

FAMILY Sleep Program

NCT06571305
View directory record Official record
Conditions
Cancer
Interventions
Brief Behavioral Treatment for Insomnia (BBTI), My Sleep Our Sleep (MSOS)
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 23, 2026, 1:24 PM EDT
Not listed Not applicable Interventional

Diabetes and Osteopathic Manipulative Medicine (OMM)

NCT03663322
View directory record Official record
Conditions
Type2 Diabetes Mellitus, Osteopathy in Diseases Classified Elsewhere
Interventions
OMT Protocol, OMT-Sham Protocol
Procedure
Lead sponsor
New York Institute of Technology
Other
Eligibility
30 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
2
States / cities
Central Islip, New York • Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated May 2, 2022 · Synced Oct 23, 2026, 1:24 PM EDT
Completed Not applicable Interventional

Contingency Management to Improve Medication for Opioid Use Disorder Continuation After the Emergency Department

NCT07129902
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
Contingency Management, Usual care as prescribed by the ED physicians
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 23, 2026, 1:24 PM EDT
Recruiting Not applicable Interventional

Virtual Reality Use for ICU Mobility

NCT07234201
View directory record Official record
Conditions
Intensive Care Unit ICU
Interventions
Nurse driven virtual reality mobility session
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Oct 23, 2026, 1:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Adolescent Self-Care and Knowledge Education in Diabetes--Improved by Texting

NCT03241212
View directory record Official record
Conditions
Type 1 Diabetes Mellitus
Interventions
Texting
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
15 Years to 21 Years
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 3, 2019 · Synced Oct 23, 2026, 1:24 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Birth Control to Improve Birth Spacing

NCT05240066
View directory record Official record
Conditions
Contraception, Contraception Behavior, Knowledge, Attitudes, Practice, Birth Spacing
Interventions
Not listed
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
1,341 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Oct 23, 2026, 1:24 PM EDT
Not listed Phase 1Phase 2 Interventional Accepts healthy volunteers

Senolytic Agent Improve the Benefit of Platelet-Rich Plasma and Losartan

NCT05025956
View directory record Official record
Conditions
Femoroacetabular Impingement
Interventions
Fisetin, Placebo
Drug
Lead sponsor
Steadman Philippon Research Institute
Other
Eligibility
18 Years to 80 Years
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Vail, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 16, 2024 · Synced Oct 23, 2026, 1:24 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Future Leaders Program: Testing a Youth Leadership, Engagement, and Mindfulness Program

NCT06736522
View directory record Official record
Conditions
Adolescent Behavior Problem, Mental Health Wellness 1
Interventions
Leadership, Engagement, and youth Action Program with Mindfulness, EnvisionIT
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
14 Years and older
Enrollment
504 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
3
States / cities
Chicago, Illinois • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 23, 2026, 1:24 PM EDT
Completed Not applicable Interventional Results available

Body Mind Training Project

NCT01564394
View directory record Official record
Conditions
Cancer Related Fatigue
Interventions
Qigong, Non-aerobic stretching
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
55 Years to 99 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
2
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Dec 8, 2015 · Synced Oct 23, 2026, 1:24 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Phase I/II Cancer Caregiver Interventions to Improve Quality of Life and Prevent Burnout

NCT02166866
View directory record Official record
Conditions
Cancer Care Recipient
Interventions
Quality of Life Questionairre and Education
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 29, 2018 · Synced Oct 23, 2026, 1:24 PM EDT
Completed Phase 3 Interventional

A Collaborative Model to Improve Blood Pressure (BP) Control and Minimize Racial Disparities

NCT00935077
View directory record Official record
Conditions
Hypertension, Asthma
Interventions
PPCM Asthma, 24 Month PPCM BP, 9 Month PPCM BP
Other
Lead sponsor
University of Iowa
Other
Eligibility
18 Years and older
Enrollment
1,441 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
28
States / cities
San Diego, California • Hartford, Connecticut • Gainesville, Florida + 25 more
Source: ClinicalTrials.gov public record
Updated Jul 10, 2014 · Synced Oct 23, 2026, 1:24 PM EDT
Active, not recruiting Not applicable Interventional

Improving Nutrition and Physical Activity for Cancer Survivors (Tools To Be Fit)

NCT05056077
View directory record Official record
Conditions
Bladder Cancer, Breast Cancer, Colon Cancer, Endometrial Cancer, Ovarian Cancer, Rectal Cancer, Prostate Cancer, Renal Cell Carcinoma, Kidney Cancer
Interventions
Counseling, Educational Intervention, Health Education, Health Promotion and Education - Direct Text Messaging, Health Promotion and Education - Digital health tool kit, Questionnaires
Other · Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
353 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 23, 2026, 1:24 PM EDT
Withdrawn Not applicable Interventional

Augmented Reality Heads-up Display to Improve Ultrasound Guided IV Access

NCT05710445
View directory record Official record
Conditions
Phlebotomy
Interventions
Augmented Reality
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 15, 2024 · Synced Oct 23, 2026, 1:24 PM EDT