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ClinicalTrials.gov public records Last synced Oct 27, 2026, 5:08 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 937–960 of 8,264 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: IMPROVED Clear all
Completed Not applicable Interventional Results available

Mindfulness-Based Relapse Prevention to Improve Medication Assisted Treatment Adherence and Drug-use Outcomes for Opioid Use Disorder

NCT05042388
View directory record Official record
Conditions
Opioid-use Disorder
Interventions
Mindfulness-Based Relapse Prevention - Rolling Admission (MBRP-RA), Treatment-As-Usual
Behavioral
Lead sponsor
West Chester University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
West Chester, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 27, 2026, 5:08 AM EDT
Completed Phase 3 Interventional Results available

Dapagliflozin Evaluation to Improve the LIVEs of Patients With PReserved Ejection Fraction Heart Failure.

NCT03619213
View directory record Official record
Conditions
Heart Failure With Preserved Ejection Fraction
Interventions
Dapagliflozin, Placebo
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
40 Years to 130 Years
Enrollment
6,263 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
66
States / cities
Fairhope, Alabama • Mobile, Alabama • Sheffield, Alabama + 57 more
Source: ClinicalTrials.gov public record
Updated Jul 11, 2023 · Synced Oct 27, 2026, 5:08 AM EDT
Completed No phase listed Observational

Leveraging ctDNA Analysis to Improve Early Detection of Cancer Recurrence in the High-Risk Melanoma Setting

NCT05079113
View directory record Official record
Conditions
Stage III Melanoma, Stage IV Cutaneous Melanoma
Interventions
Not listed
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 29, 2024 · Synced Oct 27, 2026, 5:08 AM EDT
Completed Not applicable Interventional

Cognitive Therapy to Improve Word Finding

NCT00494520
View directory record Official record
Conditions
Anomia, Aphasia, Traumatic Brain Injury, Cerebrovascular Accident
Interventions
Errorful training condition, Errorless training condition
Procedure
Lead sponsor
Georgetown University
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 19, 2017 · Synced Oct 27, 2026, 5:08 AM EDT
Completed Not applicable Interventional Results available

Communication to Improve Shared Decision-Making in ADHD

NCT02716324
View directory record Official record
Conditions
Attention-Deficit/Hyperactivity Disorder
Interventions
Care Manager CM), ADHD Portal
Behavioral · Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
5 Years to 12 Years
Enrollment
303 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 25, 2019 · Synced Oct 27, 2026, 5:08 AM EDT
Withdrawn Not applicable Interventional

Preoperative Self-managed Respiratory Therapy for Reduction of Postoperative Pulmonary Complications

NCT03356496
View directory record Official record
Conditions
Postoperative Respiratory Complication
Interventions
AirLife 4000 cc incentive spirometry device
Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 29, 2022 · Synced Oct 27, 2026, 5:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Laser 360iQ: Optimal Light-laser Combination Therapy

NCT04519723
View directory record Official record
Conditions
Photodamage
Interventions
Assess the safety and efficacy of light-laser therapy using the Harmony XL and Dye-VL (500-600nm), Q-Switched 1064nm, Er:YAG 2940nm modules in combination .
Device
Lead sponsor
Alma Lasers Inc.
Industry
Eligibility
35 Years to 60 Years · Female only
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Edina, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 20, 2020 · Synced Oct 27, 2026, 5:08 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Elucidating the Necessary Active Components of Training

NCT05366023
View directory record Official record
Conditions
Alzheimer Disease, Cognitive Change, Cognitive Impairment
Interventions
BUD1, BUD2, TDD1, TDD2, CSA10, CSA20, CSA30, CSA40
Behavioral
Lead sponsor
Clemson University
Other
Eligibility
55 Years to 85 Years
Enrollment
280 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Seneca, South Carolina
Source: ClinicalTrials.gov public record
Updated May 9, 2022 · Synced Oct 27, 2026, 5:08 AM EDT
Not listed Early Phase 1 Interventional

Does Treatment of Androgen Excess Using Spironolactone Improve Ovulatory Rates in Girls With Androgen Excess?

NCT04075149
View directory record Official record
Conditions
Polycystic Ovary Syndrome, Puberty Disorders, Ovulation Disorder
Interventions
Spironolactone
Drug
Lead sponsor
University of Virginia
Other
Eligibility
13 Years to 19 Years · Female only
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 27, 2023 · Synced Oct 27, 2026, 5:08 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Unacylated Ghrelin to Improve FuncTioning in PAD: The GIFT Trial

NCT03358355
View directory record Official record
Conditions
Peripheral Artery Disease, PAD, Peripheral Arterial Disease
Interventions
unacelyated ghrelin
Drug
Lead sponsor
Northwestern University
Other
Eligibility
55 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 12, 2020 · Synced Oct 27, 2026, 5:08 AM EDT
Terminated Not applicable Interventional Results available

Obstructive Sleep Apnea Treatment to Improve Cardiac Rehabilitation

NCT02005445
View directory record Official record
Conditions
Obstructive Sleep Apnea, Coronary Heart Disease
Interventions
CPAP, HLSE
Device · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 5, 2019 · Synced Oct 27, 2026, 5:08 AM EDT
Terminated Not applicable Interventional Results available

Mastectomy Flap Temperature Study

NCT05395936
View directory record Official record
Conditions
Breast Cancer, Mastectomy
Interventions
Myocardial Probe Temperature Screen, Data Collection
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Female only
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 4, 2024 · Synced Oct 27, 2026, 5:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Supporting Family Caregivers of Persons With Dementia

NCT05336344
View directory record Official record
Conditions
Caregiver Stress Syndrome, Anxiety, Depression
Interventions
ENCODE
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
452 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 27, 2026, 5:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Gluteal Activation Plus Movement Retraining

NCT07293039
View directory record Official record
Conditions
Movement, Abnormal, Lower Extremity Problem
Interventions
Control HEP focusing on isometric gluteal activation, Experimental HEP focusing on isometric gluteal activation plus a movement retaining program
Other
Lead sponsor
Louisiana State University Health Sciences Center Shreveport
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Shreveport, Louisiana
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 27, 2026, 5:08 AM EDT
Recruiting Phase 2 Interventional

An Acupuncture Study for People At High Risk for Sepsis

NCT06344819
View directory record Official record
Conditions
Sepsis
Interventions
Acupuncture, Sham Acupuncture
Procedure · Other
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 27, 2026, 5:08 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Preventing Obesity in Military Communities-Adolescents

NCT02671292
View directory record Official record
Conditions
Obesity, Overweight, Binge Eating
Interventions
Interpersonal Psychotherapy, Health Education
Behavioral · Other
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
12 Years to 17 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
2
States / cities
Bethesda, Maryland • Fort Belvoir, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 26, 2019 · Synced Oct 27, 2026, 5:08 AM EDT
Terminated Not applicable Interventional

Empowering Veterans to Communicate With Healthcare Providers

NCT03529071
View directory record Official record
Conditions
Chronic Kidney Disease Stage 3
Interventions
CKD-Question Prompt Sheet
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
2
States / cities
Chicago, Illinois • Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 18, 2022 · Synced Oct 27, 2026, 5:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mindful Minds: Mindfulness-Based Neurofeedback for Underrepresented College Students

NCT06784934
View directory record Official record
Conditions
Academic Performance, Anxiety
Interventions
NeuroSky Mindfulness-Based Neurofeedback
Device
Lead sponsor
Florida International University
Other
Eligibility
18 Years to 30 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Oct 27, 2026, 5:08 AM EDT
Recruiting Not applicable Interventional

Adapting and Pilot Testing a Skills-based Smoking Cessation Intervention to Address Developmental and Health-related Stress Among Adults Who Smoke

NCT06654414
View directory record Official record
Conditions
Smoking Cessation, Depression, Anxiety, Nicotine Dependence, Gender Minority Stress
Interventions
PRIDE QUIT, Enhanced Treatment As Usual (ETAU)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
3
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 27, 2026, 5:08 AM EDT
Completed Not applicable Interventional

Comparison of Immediate vs Gradual Switch to Divalproex in Adults With Intellectual Disability

NCT00347152
View directory record Official record
Conditions
Epilepsy
Interventions
Divalproex
Drug
Lead sponsor
University of Kansas
Other
Eligibility
18 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Sep 12, 2008 · Synced Oct 27, 2026, 5:08 AM EDT
Completed Not applicable Interventional Results available

Continuous Positive Airway Pressure to Improve Milder Obstructive Sleep Apnea

NCT00089752
View directory record Official record
Conditions
Lung Diseases, Sleep Apnea Syndromes, Hypertension
Interventions
Continuous Positive Airway Pressure (CPAP) Treatment, Sham CPAP device - CPAP device with pressure delivered <1 cm H20
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 100 Years
Enrollment
281 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
4
States / cities
Denver, Colorado • Atlanta, Georgia • Long Island City, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 24, 2017 · Synced Oct 27, 2026, 5:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Training of Eccentric Lower Extremity Function After SCI

NCT02498548
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Trained SCI Knee or Trained SCI Hip
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 90 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 19, 2021 · Synced Oct 27, 2026, 5:08 AM EDT
Recruiting Not applicable Interventional

Cognitive Training Intervention and Attitudes Towards Genetics

NCT03094026
View directory record Official record
Conditions
Cognitive Impairment, Hematologic Neoplasms, Hematopoietic Cell Transplant
Interventions
Lumosity, Lumosity (waitlist control)
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
21 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Oct 27, 2026, 5:08 AM EDT
Recruiting Not applicable Interventional

PRC With Meniscal Allograft Arthroplasty for Wrist Osteoarthritis

NCT05412615
View directory record Official record
Conditions
Wrist Osteoarthritis
Interventions
Meniscus Allograft Transplantation with Proximal Row Carpectomy, Proximal Row Carpectomy
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
30 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Englewood, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 10, 2025 · Synced Oct 27, 2026, 5:08 AM EDT