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ClinicalTrials.gov public records Last synced Sep 6, 2026, 7:51 AM EDT

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Showing 1–24 of 3,423 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Implant Procedure Clear all
Completed Not applicable Interventional Results available

NHLBI DIR LAMPOON Study: Intentional Laceration of the Anterior Mitral Leaflet to Prevent Left Ventricular Outflow Tract Obstruction During Transcatheter Mitral Valve Implantation

NCT03015194
View directory record Official record
Conditions
Mitral Valve Failure
Interventions
Edwards SAPIEN 3 transcatheter heart valve, ASHI INTECC Astato XS 20
Device
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
21 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
6
States / cities
Washington D.C., District of Columbia • Atlanta, Georgia • Detroit, Michigan + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Sep 6, 2026, 7:51 AM EDT
Not listed Not applicable Interventional

The Effects of Ultrasound on Central Nervous System

NCT04192149
View directory record Official record
Conditions
Focused Ultrasound
Interventions
Focused Ultrasound
Other
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 85 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 9, 2019 · Synced Sep 6, 2026, 7:51 AM EDT
Suspended Not applicable Interventional

Closed Loop Spinal Cord Stimulation for Chemotherapy Induced Peripheral Neuropathy, a Pilot Study.

NCT06616649
View directory record Official record
Conditions
Peripheral Neuropathy Due to Chemotherapy
Interventions
Spinal cord stimulator implant
Device
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Sep 6, 2026, 7:51 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Surgeon-Initiated Bone Health Referral Pathway in Patients Undergoing Lower Extremity Arthroplasty

NCT05845021
View directory record Official record
Conditions
Osteoporosis, Arthroplasty Complications, Fragility Fracture
Interventions
Surgeon-Initiated Bone Health Referral Pathway
Combination Product
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years and older
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Columbia, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 13, 2025 · Synced Sep 6, 2026, 7:51 AM EDT
Active, not recruiting Not applicable Interventional

Split Chest Breast Neurotization

NCT05757778
View directory record Official record
Conditions
Breast Implant; Complications
Interventions
Sensory Nerve Coaptation
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Sep 6, 2026, 7:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

CI532 - Early Experience Study

NCT02755935
View directory record Official record
Conditions
Sensorineural Hearing Loss, Bilateral
Interventions
Cochlear Nucleus CI532
Device
Lead sponsor
Cochlear
Industry
Eligibility
12 Months and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
6
States / cities
Skokie, Illinois • Iowa City, Iowa • Ann Arbor, Michigan + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 19, 2018 · Synced Sep 6, 2026, 7:51 AM EDT
Completed Phase 1 Interventional Results available

Vaccine Therapy and GM-CSF in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndromes, Non-Small Cell Lung Cancer, or Mesothelioma

NCT00398138
View directory record Official record
Conditions
Leukemia, Lung Cancer, Malignant Mesothelioma, Myelodysplastic Syndromes, Primary Peritoneal Cavity Cancer
Interventions
WT-1 analog peptide vaccine, incomplete Freund's adjuvant, sargramostim, polymerase chain reaction, flow cytometry, immunoenzyme technique
Biological · Genetic · Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years to 120 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 1, 2016 · Synced Sep 6, 2026, 7:51 AM EDT
Active, not recruiting Phase 3 Interventional

Bupivacaine vs Placebo for Unilateral Mastectomy Surgical Site Post-operative Pain Control

NCT03351348
View directory record Official record
Conditions
Breast Cancer
Interventions
Bupivacaine, patient-reported pain scores, saline
Drug · Behavioral · Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
165 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Sep 6, 2026, 7:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Influence of Mucosa Tissue Thickness on Marginal Bone Loss of Implants With Smooth Collars

NCT02925078
View directory record Official record
Conditions
Gingival Tissue
Interventions
Biohorizons Tapered Internal Implant, Laser-Lok, Resorbable Blast Textured (RBT)
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 25, 2020 · Synced Sep 6, 2026, 7:51 AM EDT
Not listed Not applicable Interventional

Rib Fixation for Clinically Severe Rib Fractures From Trauma

NCT02595593
View directory record Official record
Conditions
Rib Fracture, Flail Chest
Interventions
Rib Fixation System
Device
Lead sponsor
Darwin Ang
Other
Eligibility
18 Years to 90 Years
Enrollment
236 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
10
States / cities
Fort Walton Beach, Florida • Ft. Pierce, Florida • Kissimmee, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated May 9, 2022 · Synced Sep 6, 2026, 7:51 AM EDT
Completed Not applicable Interventional Results available

Performance Evaluation of the AMS CONTINUUM™ Device

NCT00894933
View directory record Official record
Conditions
Prostate Cancer
Interventions
CONTINUUM™
Device
Lead sponsor
American Medical Systems
Industry
Eligibility
40 Years and older · Male only
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
6
States / cities
Little Rock, Arkansas • Burlington, Massachusetts • Rochester, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 21, 2018 · Synced Sep 6, 2026, 7:51 AM EDT
Withdrawn Not applicable Interventional

Transcranial Direct Current Stimulation and Cognitive Remediation Therapy for Interictal Dysfunction in Epilepsy

NCT02950506
View directory record Official record
Conditions
Epilepsy
Interventions
transcranial direct current stimulation, Cognitive Remediation Therapy
Device · Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 64 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Saint Louis Park, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 17, 2022 · Synced Sep 6, 2026, 7:51 AM EDT
Active, not recruiting Not applicable Interventional

REDUCE LAP-HF TRIAL II

NCT03088033
View directory record Official record
Conditions
Heart Failure
Interventions
IASD System II implant, intra-cardiac echocardiography (ICE), or transesophageal echocardiography (TEE)
Device · Other
Lead sponsor
Corvia Medical
Industry
Eligibility
40 Years and older
Enrollment
608 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
44
States / cities
Phoenix, Arizona • Tucson, Arizona • La Jolla, California + 36 more
Source: ClinicalTrials.gov public record
Updated Feb 21, 2023 · Synced Sep 6, 2026, 7:51 AM EDT
Recruiting Not applicable Interventional

A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)

NCT07286578
View directory record Official record
Conditions
Cardiovascular Diseases, Myocardial Ischemia, Heart Diseases, Arteriosclerosis, Arterial Occlusive Diseases, Vascular Diseases, Coronary Artery Disease
Interventions
CT(Computed Tomography) guided Percutaneous Coronary Intervention, IVUS (Intravascular Ultrasound) guided Percutaneous Coronary Intervention
Device
Lead sponsor
Fundación EPIC
Other
Eligibility
18 Years to 85 Years
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
5
States / cities
Boston, Massachusetts • Minneapolis, Minnesota • Jersey City, New Jersey + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 9, 2026 · Synced Sep 6, 2026, 7:51 AM EDT
Completed Not applicable Interventional Results available

Electric-Acoustic Stimulation Extended Follow-up Post Approval Study

NCT03031678
View directory record Official record
Conditions
Hearing Loss, Sensorineural
Interventions
Electric-Acoustic Stimulation (EAS) Cochlear Implant System
Device
Lead sponsor
Med-El Corporation
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
7
States / cities
Palo Alto, California • Miami, Florida • Kansas City, Kansas + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 9, 2020 · Synced Sep 6, 2026, 7:51 AM EDT
Completed Not applicable Interventional

Auditory Neural Function in Implanted Patients With Usher Syndrome

NCT04906135
View directory record Official record
Conditions
Usher Syndrome, Cochlear Implantation
Interventions
Experimental manipulation of stimulation parameters
Other
Lead sponsor
Ohio State University
Other
Eligibility
1 Year to 85 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
4
States / cities
Boston, Massachusetts • Columbus, Ohio • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 28, 2025 · Synced Sep 6, 2026, 7:51 AM EDT
Recruiting Not applicable Interventional

Acupuncture Therapy for Pediatric Disorders of Gut-Brain Interaction

NCT07435610
View directory record Official record
Conditions
Disorders of Gut-brain Interaction
Interventions
Active Therapeutic acupuncture intervention, Sham therapeutic acupuncture treatment
Other
Lead sponsor
Children's Hospital of Orange County
Other
Eligibility
8 Years to 17 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Sep 6, 2026, 7:51 AM EDT
Terminated Not applicable Interventional

Minimally Invasive Tongue Suture For Obstructive Sleep Apnea

NCT00515580
View directory record Official record
Conditions
Obstructive Sleep Apnea, Upper Airway Resistance Syndrome
Interventions
Tongue Sutures for Obstructive Sleep Apnea
Procedure
Lead sponsor
West Side ENT
Other
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 19, 2012 · Synced Sep 6, 2026, 7:51 AM EDT
Completed Phase 1 Interventional

Study in Stabilized Schizophrenic Patients to Evaluate the Pharmacokinetics of Risperidone and 9-Hydroxy (OH)-Risperidone When Risperidone is Administered From a Polyurethane Implant

NCT01774435
View directory record Official record
Conditions
Schizophrenia
Interventions
EN3342
Drug
Lead sponsor
Endo USA Inc., a Keenova Therapeutics Company
Industry
Eligibility
18 Years to 60 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Marlton, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 2, 2014 · Synced Sep 6, 2026, 7:51 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Apoptotic Cell (AC) Uptake by Human Alveolar Macrophages (AM)

NCT01099410
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
Fiberoptic bronchoscopy, blood draw, intravenous catheter
Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 5, 2016 · Synced Sep 6, 2026, 7:51 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Tryton Post Approval Study (PAS) for the Tryton Side Branch Stent

NCT03318796
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Coronary Artery Stenting
Device
Lead sponsor
Tryton Medical, Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
335 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 25, 2019 · Synced Sep 6, 2026, 7:51 AM EDT
Completed Phase 3 Interventional Results available

Effectiveness of Ultrafiltration in Treating People With Acute Decompensated Heart Failure and Cardiorenal Syndrome (The CARRESS Study)

NCT00608491
View directory record Official record
Conditions
Heart Failure
Interventions
Stepped pharmacologic care, Ultrafiltration
Drug · Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
8
States / cities
Phoenix, Arizona • Atlanta, Georgia • Minneapolis, Minnesota + 5 more
Source: ClinicalTrials.gov public record
Updated Jun 23, 2013 · Synced Sep 6, 2026, 7:51 AM EDT
Withdrawn Phase 2 Interventional

Apixaban in Patients Who Undergo CIED Procedure- Randomized Pilot Study

NCT02450682
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Apixaban, Warfarin
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 17, 2016 · Synced Sep 6, 2026, 7:51 AM EDT
Terminated Not applicable Interventional Results available

Thalamic Deep Brain Stimulation for the Treatment of Refractory Tourette Syndrome

NCT01817517
View directory record Official record
Conditions
Tourette Syndrome
Interventions
Medtronic Activa Deep Brain Stimulation System
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
15 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Sep 6, 2026, 7:51 AM EDT