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ClinicalTrials.gov public records Last synced Nov 14, 2026, 11:14 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 238 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Implantable Cardioverter Defibrillator Clear all

Conditions: Heart Failure; With Decompensation
Interventions: Medtronic ICDs, CRT-Ds, and CRT-Ps; Device
Lead sponsor: Charles Porter, MD; Other
Eligibility: 18 Years and older
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: Sudden Cardiac Death
Interventions: Cardiac Resynchronization Therapy - Defibrillator (CRT-D); Device
Lead sponsor: Abbott Medical Devices; Industry
Eligibility: 18 Years and older
Enrollment: 77 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 2
States / cities: Santa Monica, California • Colorado Springs, Colorado

Conditions: Heart Failure, Patients Undergoing CRT-D Device Implantation
Interventions: Not listed
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 100 Years
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2022
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Sarcoidosis of the Heart, Cardiomyopathy
Interventions: Not listed
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Cardiovascular Disease
Interventions: Not listed
Lead sponsor: National Institutes of Health Clinical Center (CC); NIH
Eligibility: Not listed
Enrollment: 125 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2004
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Myocardial Infarction, Arrhythmia, Ventricular, Ischemic Cardiomyopathy
Interventions: T Wave Alternans Test; Procedure
Lead sponsor: Medtronic Cardiac Rhythm and Heart Failure; Industry
Eligibility: Not listed
Enrollment: 656 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2007
U.S. locations: 47
States / cities: Mobile, Alabama • Phoenix, Arizona • Walnut Creek, California + 44 more

Conditions: Lead Extraction Procedures
Interventions: Not listed
Lead sponsor: Oregon Health and Science University; Other
Eligibility: Not listed
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2027
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Bradycardia, Heart Failure
Interventions: CRT-D Implantation, CRT-P Implantation, Dual Chamber Pacemaker Implantation; Procedure
Lead sponsor: Yong-Mei Cha; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2026
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Congestive Heart Failure, Coronary Artery Disease, Myocardial Infarction
Interventions: MyoCell™ Autologous Myoblasts; Drug
Lead sponsor: Bioheart, Inc.; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006
U.S. locations: 5
States / cities: Fort Lauderdale, Florida • Atlanta, Georgia • Chicago, Illinois + 2 more

Conditions: Shock
Interventions: ICD/ CRT-D; Device
Lead sponsor: Abbott Medical Devices; Industry
Eligibility: 18 Years and older
Enrollment: 1,670 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Coronary Artery Disease
Interventions: Fortify® ST, Fortify Assura® ST, Ellipse® ST family of devices; Device
Lead sponsor: Abbott Medical Devices; Industry
Eligibility: 18 Years and older
Enrollment: 2,258 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2017
U.S. locations: 97
States / cities: Birmingham, Alabama • Huntsville, Alabama • Mesa, Arizona + 85 more

Conditions: Heart Failure
Interventions: Subcutaneous adipose tissue collection, Peripheral arterial tonometry (PAT); Procedure · Diagnostic Test
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2021
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Heart Failure
Interventions: Chronicle Implantable Hemodynamic Monitor (IHM) System, Chronicle Implantable Cardioverter Defibrillator (ICD); Device
Lead sponsor: Medtronic Cardiac Rhythm and Heart Failure; Industry
Eligibility: 18 Years and older
Enrollment: 165 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 19
States / cities: Birmingham, Alabama • Springfield, Illinois • Fort Wayne, Indiana + 16 more

Conditions: Anxiety Disorder in Conditions Classified Elsewhere
Interventions: mindfulness based intervention (MBI), usual care; Behavioral
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 21 Years and older
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Worcester, Massachusetts

Conditions: Heart Failure, ICD, Chronotropic Incompetence
Interventions: CLS Mode on Biotronik CRT-D, Accelerometer Mode on Biotronik CRT-D; Device
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 99 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Sudden Cardiac Death
Interventions: Electrophysiology study (EPS), Standard Care, Cardiac Magnetic Resonance (CMR); Procedure · Other
Lead sponsor: Western Sydney Local Health District; Other
Eligibility: 18 Years to 85 Years
Enrollment: 1,058 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2029
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Heart Failure
Interventions: Cardiac Resynchronization Therapy (CRT) Device or Implantable Cardioverter Defibrillator (ICD) with CRT; Device
Lead sponsor: Medtronic Cardiac Rhythm and Heart Failure; Industry
Eligibility: 18 Years and older
Enrollment: 684 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2011
U.S. locations: 34
States / cities: Huntsville, Alabama • Anchorage, Alaska • Redwood City, California + 31 more

Conditions: Congestive Heart Failure
Interventions: Paradym CRT + Physiological Diagnosis (PhD); Device
Lead sponsor: ELA Medical, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 520 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Mesa, Arizona

Conditions: Arrhythmia, Bradycardia, Heart Failure, Sinus Tachycardia
Interventions: Device; Device
Lead sponsor: Medtronic; Industry
Eligibility: Not listed
Enrollment: 20,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1983 – 2040
U.S. locations: 114
States / cities: Birmingham, Alabama • Anchorage, Alaska • Chandler, Arizona + 111 more

Conditions: Ventricular Tachycardia
Interventions: amiodarone, sotalol, Biosense Webster's NAVI-STAR Thermo-Cool; Drug · Device
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 5
States / cities: Baltimore, Maryland • Durham, North Carolina • Columbus, Ohio + 2 more

Conditions: Heart Failure
Interventions: HeartNet Ventricular Support System, Optimal Medical/Device Therapy; Device · Drug
Lead sponsor: Paracor Medical, Inc; Industry
Eligibility: 18 Years to 74 Years
Enrollment: 220 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2012
U.S. locations: 29
States / cities: Birmingham, Alabama • Los Angeles, California • San Francisco, California + 26 more

Conditions: Tachyarrhythmias, Sudden Cardiac Death, Heart Failure
Interventions: SJ4 connector and RV high voltage SJ4 lead; Device
Lead sponsor: Abbott Medical Devices; Industry
Eligibility: 18 Years and older
Enrollment: 1,701 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2015
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Arrhythmia, Cardiac
Interventions: recorded patients; Other
Lead sponsor: NewPace Ltd; Industry
Eligibility: Not listed
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Atlantis, Florida

Conditions: Shared Decision-making
Interventions: Arm A: Online, patient-facing decision-making aid (app) with personalized risk information., Arm B - Online, patient-facing decision-making app without personalized risk information., Arm C - Usual Care/No Device; Device · Other
Lead sponsor: Stanford University; Other
Eligibility: 60 Years and older
Enrollment: 600 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 2
States / cities: San Francisco, California • Greenville, North Carolina

Search by objective public record fields.

Dynamic Thoracic Impedance as a Marker for Heart Failure Decompensation

'Effect of CRT on Defibrillation Threshold Estimates' Study

Reverse Electrical Remodeling of Native Conduction in Cardiac Resynchronization Therapy

Implantable Cardiac Defibrillators for the Prevention of Sudden Death in Patients With Cardiac Sarcoidosis

Technology Dependency and Health-Related Quality of Life

MASTER I - Microvolt T Wave Alternans Testing for Risk Stratification of Post MI Patients

Pacemaker and Defibrillator Lead Extraction Registry

His Bundle Pacing in Bradycardia and Heart Failure

Autologous Cultured Myoblasts (BioWhittaker) Transplanted Via Myocardial Injection

Programming Implantable Cardioverter Defibrillators in Patients With Primary Prevention Indication

ST Monitoring to Detect Acute Coronary Syndrome Events in Implantable Cardioverter Defibrillator Patients

Vascular Endothelial Function and Cardiac Resynchronization Response in Patients With Heart Failure

Extension Phase of the Chronicle® Offers Management to Patients With Advanced Signs & Symptoms of Heart Failure Study

A Mindfulness-based Intervention for Treatment of Anxiety in ICD (Implantable Cardioverter Defibrillator) Patients

Comparing Rate Response With CLS Versus Accelerometer ICD Settings in Heart Failure Patients With BIOTRONIK CRT-Ds

Programmed Ventricular Stimulation to Risk Stratify for Early Cardioverter-Defibrillator (ICD) Implantation to Prevent Tachyarrhythmias Following Acute Myocardial Infarction (PROTECT-ICD)

REsynchronization reVErses Remodeling in Systolic Left vEntricular Dysfunction (REVERSE)

Evaluation of a Diagnostic Feature in a Cardiac Resynchronization Therapy (CRT) Device

Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

Pilot Study of Catheter Ablation for Ventricular Tachycardia in Patients With an Implantable Cardioverter Defibrillator

Prospective Evaluation of Elastic Restraint to LESSen the Effects of Heart Failure (PEERLESS-HF) Trial

SJ4 Post Approval Study in Implantable Cardioverter-Defibrillator and Cardiac Resynchronization Therapy Defibrillator Patients

Surface Electrocardiogram (ECG) Signal Recording for Implantable Subcutaneous String Defibrillator (ISSD) Development

Evaluating a Digital Aid to Improve ICD Decisions