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ClinicalTrials.gov public records Last synced Oct 10, 2026, 10:34 PM EDT

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Showing 25–48 of 202 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Implantable cardioverter-defibrillator (ICD) Clear all
Completed Not applicable Interventional

A Randomised Trial of S-ICD Implantation With and Without Defibrillation Testing

NCT03495297
View directory record Official record
Conditions
Ventricular Arrythmia
Interventions
ommitence of defibrillation testing
Procedure
Lead sponsor
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Other
Eligibility
18 Years and older
Enrollment
965 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
7
States / cities
Orlando, Florida • Atlanta, Georgia • Chicago, Illinois + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Oct 10, 2026, 10:34 PM EDT
Completed Not applicable Interventional Results available

Pan-Asia United States PrEvention of Sudden Cardiac Death Catheter Ablation Trial

NCT02848781
View directory record Official record
Conditions
Ventricular Tachycardia (VT)
Interventions
Implantable Cardioverter Defibrillator (ICD), Catheter Ablation
Device · Procedure
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 14, 2022 · Synced Oct 10, 2026, 10:34 PM EDT
Not listed No phase listed Observational

Gut Microbiome and Ventricular Arrhythmias

NCT04466072
View directory record Official record
Conditions
Ventricular Tachycardia, Ventricular Fibrillation, Gut Microbiome
Interventions
Stool test for microbial analysis
Diagnostic Test
Lead sponsor
North Florida Foundation for Research and Education
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 18, 2022 · Synced Oct 10, 2026, 10:34 PM EDT
Completed Phase 4 Interventional

Optimal Anti-tachycardia Therapy in Implantable Cardioverter-defibrillator (ICD) Patients Without Pacing Indications

NCT00729703
View directory record Official record
Conditions
Tachycardia
Interventions
OVATIO DR 6550
Device
Lead sponsor
LivaNova
Industry
Eligibility
18 Years and older
Enrollment
462 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
5
States / cities
Atlanta, Georgia • Decatur, Georgia • Mandeville, Louisiana + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 13, 2015 · Synced Oct 10, 2026, 10:34 PM EDT
Not listed No phase listed Observational

Does Lung Impedance Correlate With Changes in BNP in Stable and Acutely Decompensated Heart Failure Patients?

NCT00560339
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Not listed
Lead sponsor
Southern New Jersey Cardiac Specialists
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
6
States / cities
Glendale, California • Voorhees Township, New Jersey • Roslyn, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Nov 19, 2007 · Synced Oct 10, 2026, 10:34 PM EDT
Completed Not applicable Interventional Results available

Detect Fluid Early From Intra-thoracic Impedance Monitoring

NCT00916929
View directory record Official record
Conditions
Heart Failure
Interventions
Impedance Monitoring Feature
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
34
States / cities
Birmingham, Alabama • Phoenix, Arizona • Little Rock, Arkansas + 29 more
Source: ClinicalTrials.gov public record
Updated Feb 19, 2019 · Synced Oct 10, 2026, 10:34 PM EDT
Completed Not applicable Interventional

Barriers to Use of Remote Monitoring in Patients With Implantable Cardioverter Defibrillators

NCT02361333
View directory record Official record
Conditions
Cardiac Patients, Implantable Cardioverter Defibrillator
Interventions
Teaching Intervention
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 17, 2018 · Synced Oct 10, 2026, 10:34 PM EDT
Completed Phase 4 Interventional Results available

POWER (Pulse Width Optimized Waveform Evaluation Trial)

NCT00311181
View directory record Official record
Conditions
Sudden Cardiac Death
Interventions
Implantable Cardioverter Defibrillator (ICD), Cardiac Resynchronization Therapy (CRT-D)
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
217 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
2
States / cities
Birmingham, Alabama • Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Feb 20, 2019 · Synced Oct 10, 2026, 10:34 PM EDT
Not listed Not applicable Interventional

Sodium Channel Splicing in Heart Failure Trial (SOCS-HEFT) Prospective Study

NCT02738749
View directory record Official record
Conditions
Death, Sudden, Cardiac
Interventions
Implantable cardioverter-defibrillator (ICD)
Device
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 12, 2017 · Synced Oct 10, 2026, 10:34 PM EDT
Completed Phase 4 Interventional

Reduce Ventricular Pacing in Dual Chamber Implantable Cardioverter Defibrillators Using AutoIntrinsic Conduction Search Study

NCT00187239
View directory record Official record
Conditions
Arrhythmia
Interventions
Autointrinsic Conduction Search Algorithm
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
157 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Pomona, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 4, 2019 · Synced Oct 10, 2026, 10:34 PM EDT
Terminated Not applicable Interventional

Comparative Effectiveness of Prophylactic ICD Versus Non-ICD Therapy

NCT06543446
View directory record Official record
Conditions
Heart Failure With Reduced Ejection Fraction
Interventions
ICD implantation
Procedure
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
3,290 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
13
States / cities
Portland, Maine • Baltimore, Maryland • Boston, Massachusetts + 10 more
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Oct 10, 2026, 10:34 PM EDT
Completed Not applicable Interventional Results available

Reducing Decompensation Events Utilizing Intracardiac Pressures in Patients With Chronic Heart Failure (HF) (REDUCEhf)

NCT00354159
View directory record Official record
Conditions
Heart Failure
Interventions
Implantable Hemodynamic Monitor (Chronicle® IHM), and IHM in combination with single chamber ICD (Chronicle ICD)
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
442 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
52
States / cities
Birmingham, Alabama • La Jolla, California • Loma Linda, California + 43 more
Source: ClinicalTrials.gov public record
Updated Aug 9, 2012 · Synced Oct 10, 2026, 10:34 PM EDT
Completed Phase 2 Interventional Results available

Evaluating Ventricular Arrhythmia in Subjects With Implantable Cardioverter Defibrillator or Cardiac Resynchronization Therapy-Defibrillator

NCT02104583
View directory record Official record
Conditions
Ventricular Arrhythmia
Interventions
Eleclazine, Placebo to match eleclazine
Drug
Lead sponsor
Gilead Sciences
Industry
Eligibility
18 Years to 80 Years
Enrollment
313 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
37
States / cities
Mesa, Arizona • Long Beach, California • Los Angeles, California + 32 more
Source: ClinicalTrials.gov public record
Updated Apr 9, 2019 · Synced Oct 10, 2026, 10:34 PM EDT
Recruiting Not applicable Interventional

Safety and Effectiveness of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere VT)

NCT07585968
View directory record Official record
Conditions
Ventricular Tachycardia
Interventions
Sphere-9 Catheter with the Affera Mapping and Ablation System
Device
Lead sponsor
Medtronic Cardiac Ablation Solutions
Industry
Eligibility
18 Years to 85 Years
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
5
States / cities
Indianapolis, Indiana • Manhasset, New York • Winston-Salem, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 10, 2026, 10:34 PM EDT
Completed No phase listed Observational

First Arrhythmia Collection of Transvenous and Simultaneous Subcutaneous Implantable Defibrillator Data

NCT01161589
View directory record Official record
Conditions
Ventricular Tachycardia, Ventricular Fibrillation, Atrial Fibrillation
Interventions
Not listed
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
3
States / cities
Chicago, Illinois • Charleston, South Carolina • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 16, 2017 · Synced Oct 10, 2026, 10:34 PM EDT
Recruiting No phase listed Observational

Implantable Cardioverter Defibrillator (ICD Registry)

NCT01999140
View directory record Official record
Conditions
Heart Failure, Nonischemic Cardiomyopathy, Ischemic Cardiomyopathy, Ventricular Arrhythmia, Complications; Device, Cardiac
Interventions
Not listed
Lead sponsor
American College of Cardiology
Other
Eligibility
Not listed
Enrollment
1,750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2030
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 18, 2024 · Synced Oct 10, 2026, 10:34 PM EDT
Completed No phase listed Observational

Utility of the Audible Alert in Current Generation Medtronic Implantable Cardioverter-defibrillators

NCT01605500
View directory record Official record
Conditions
Patients With a Generation 2 Medtronic Implantable Cardioverter-defibrillator(ICD)
Interventions
Not listed
Lead sponsor
Englewood Hospital and Medical Center
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Englewood, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 19, 2016 · Synced Oct 10, 2026, 10:34 PM EDT
Not listed No phase listed Observational

The Registry Evaluating Functional Outcomes of Resynchronization Management

NCT00959179
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Not listed
Lead sponsor
Saint Luke's Health System
Other
Eligibility
18 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
2
States / cities
Elgin, Illinois • Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Aug 14, 2009 · Synced Oct 10, 2026, 10:34 PM EDT
Completed Not applicable Interventional

Truncal Blocks Versus Wound Infiltration for SICD

NCT04974762
View directory record Official record
Conditions
Intraoperative Pain, Postoperative Pain
Interventions
Wound infiltration, Truncal blocks
Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 4, 2022 · Synced Oct 10, 2026, 10:34 PM EDT
Completed No phase listed Observational

3T MRI CIED Post-Approval Study

NCT02969395
View directory record Official record
Conditions
Cardiac Rhythm Disorder
Interventions
Not listed
Lead sponsor
Medtronic
Industry
Eligibility
Not listed
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
118
States / cities
Birmingham, Alabama • Anchorage, Alaska • Chandler, Arizona + 115 more
Source: ClinicalTrials.gov public record
Updated Aug 22, 2022 · Synced Oct 10, 2026, 10:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparing Rate Response With CLS Versus Accelerometer ICD Settings in Heart Failure Patients With BIOTRONIK CRT-Ds

NCT02693262
View directory record Official record
Conditions
Heart Failure, ICD, Chronotropic Incompetence
Interventions
CLS Mode on Biotronik CRT-D, Accelerometer Mode on Biotronik CRT-D
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 99 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Aug 5, 2021 · Synced Oct 10, 2026, 10:34 PM EDT
Completed No phase listed Observational

iPod and Other MP3 Players on ICDs and Pacemakers in Children

NCT00542854
View directory record Official record
Conditions
Heart Block, Bradycardia, Tachycardia, Arrhythmia
Interventions
MP3
Device
Lead sponsor
Boston Children's Hospital
Other
Eligibility
4 Years to 55 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 28, 2009 · Synced Oct 10, 2026, 10:34 PM EDT
Completed No phase listed Observational

Patient and Physician Survey Determinants of Appropriate ICD Utilization

NCT01514773
View directory record Official record
Conditions
Heart Failure, Systolic
Interventions
Not listed
Lead sponsor
Todd M Koelling, MD
Other
Eligibility
18 Years and older
Enrollment
452 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 17, 2017 · Synced Oct 10, 2026, 10:34 PM EDT
Completed Not applicable Interventional Results available

S-ICD® System IDE Clinical Study

NCT01064076
View directory record Official record
Conditions
Tachycardia, Ventricular
Interventions
S-ICD System
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
330 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
28
States / cities
Scottsdale, Arizona • Los Angeles, California • Pasadena, California + 22 more
Source: ClinicalTrials.gov public record
Updated Mar 27, 2017 · Synced Oct 10, 2026, 10:34 PM EDT