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Showing 1–24 of 352 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: In-Person weight loss Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Nutrition, Exercise, and Technology for Weight Loss

NCT02731768
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Standard, Social support-enhanced, Fitbit Zip, Digital body weight scale
Behavioral · Device
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 17, 2018 · Synced Sep 2, 2026, 7:41 PM EDT
Completed Phase 2Phase 3 Interventional

Delivering an Evidence-Based Lifestyle Intervention Via the Internet: A Randomized Controlled Study

NCT01043718
View directory record Official record
Conditions
Obesity
Interventions
More-Intensive, Less-Intensive
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 13, 2016 · Synced Sep 2, 2026, 7:41 PM EDT
Completed Not applicable Interventional

Changing Healthy Outcomes In Clinic Environments

NCT00674518
View directory record Official record
Conditions
Obesity, Physical Inactivity, Diabetes
Interventions
One on one counseling, Group/team - based health education, PACE physician counseling
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
30 Years to 65 Years
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 19, 2019 · Synced Sep 2, 2026, 7:41 PM EDT
Terminated Not applicable Interventional Results available

Diet and Exercise Program to Promote Weight Loss and Improve Health in Men With Low- or Low-Intermediate-Risk Prostate Cancer

NCT02454517
View directory record Official record
Conditions
Prostate Adenocarcinoma, Stage I Prostate Cancer AJCC V7, Stage IIA Prostate Cancer AJCC v7
Interventions
Behavioral Dietary Intervention, Exercise Intervention, Informational Intervention, Laboratory Biomarker Analysis, Quality-of-Life Assessment, Questionnaire Administration
Behavioral · Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
40 Years and older · Male only
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 3, 2023 · Synced Sep 2, 2026, 7:41 PM EDT
Completed Phase 2 Interventional

The Comparison of a Technology-Based System and an In-Person Behavioral Weight Loss Intervention

NCT01134874
View directory record Official record
Conditions
Obesity
Interventions
Standard weight loss intervention, Standard weight loss intervention plus technology, Technology only
Behavioral
Lead sponsor
John M. Jakicic, PhD
Other
Eligibility
18 Years to 55 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 4, 2015 · Synced Sep 2, 2026, 7:41 PM EDT
Completed Phase 3 Interventional

Lifestyle, Exercise and Nutrition Study 1

NCT02109068
View directory record Official record
Conditions
Breast Cancer, Weight Loss
Interventions
Weight Loss Counseling- Phone, Weight Loss Counseling- In-Person
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 8, 2014 · Synced Sep 2, 2026, 7:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Lose Now North Carolina Community Weight Loss Program

NCT01615471
View directory record Official record
Conditions
Obesity
Interventions
Group weight loss with companion internet
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 65 Years
Enrollment
195 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 23, 2017 · Synced Sep 2, 2026, 7:41 PM EDT
Completed Phase 2 Interventional

Innovative Approaches to Diet, Exercise and Activity

NCT01131871
View directory record Official record
Conditions
Body Weight
Interventions
Standard Behavioral Weight Loss Intervention, Enhanced Weight Loss Intervention
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 35 Years
Enrollment
471 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 4, 2015 · Synced Sep 2, 2026, 7:41 PM EDT
Completed Not applicable Interventional

BfedBwell Proof-of-Concept Pilot

NCT06191666
View directory record Official record
Conditions
Cancer Survivorship, Obesity, Overweight
Interventions
Group-based education and discussion, Individual 1:1 counseling, Group based behavioral skills development and cooking demonstrations, BfitBwell
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Sep 2, 2026, 7:41 PM EDT
Recruiting Phase 3 Interventional

A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain

NCT07481630
View directory record Official record
Conditions
Obesity, Knee Osteoarthritis (OA)
Interventions
NNC0487-0111, Placebo (matched to NNC0487-0111 )
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
19
States / cities
Phoenix, Arizona • Walnut Creek, California • Hamden, Connecticut + 16 more
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 2, 2026, 7:41 PM EDT
Completed Not applicable Interventional

Lifestyle Intervention to Improve Bone Quality

NCT03329963
View directory record Official record
Conditions
Aging, Obesity
Interventions
Healthy Lifestyle Intervention, Lifestyle Intervention
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
65 Years to 85 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 5, 2025 · Synced Sep 2, 2026, 7:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sustainability of MOVE UP Lifestyle Intervention

NCT03963830
View directory record Official record
Conditions
Body Weight, Diet, Healthy, Physical Disability
Interventions
MOVE UP
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
60 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 1, 2021 · Synced Sep 2, 2026, 7:41 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Complex Effects of Dietary Manipulation on Metabolic Function, Inflammation and Health

NCT02706262
View directory record Official record
Conditions
Obesity, Insulin Resistance
Interventions
Metabolically abnormal obese - Mediterranean diet, Metabolically abnormal obese - Low carbohydrate ketogenic diet, Metabolically abnormal obese - Plant-based, very-low-fat diet, Annual Follow-up Visits
Other · Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 55 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Sep 2, 2026, 7:41 PM EDT
Active, not recruiting Not applicable Interventional

The Inspiring Action to Prevent Diabetes Intervention

NCT06001801
View directory record Official record
Conditions
PreDiabetes
Interventions
Diabetes Prevention Program, INSPIRA
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Sep 2, 2026, 7:41 PM EDT
Completed Phase 2 Interventional

Diet, Exercise, and Breastfeeding Intervention Program for Women With Gestational Diabetes (DEBI Trial)

NCT00460018
View directory record Official record
Conditions
Gestational Diabetes Mellitus
Interventions
Diet, Exercise, and Breastfeeding Intervention
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
20 Years to 45 Years · Female only
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2005
U.S. locations
5
States / cities
Oakland, California • San Francisco, California • Santa Clara, California + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 18, 2009 · Synced Sep 2, 2026, 7:41 PM EDT
Completed Not applicable Interventional Results available

Peer Navigators to Address Obesity-Related Concerns for African Americans With Serious Mental Illness

NCT03382782
View directory record Official record
Conditions
Obesity, Mental Disorder
Interventions
BWLI, BWLI & Peer Navigator, Integrated Care
Behavioral
Lead sponsor
Illinois Institute of Technology
Other
Eligibility
18 Years and older
Enrollment
234 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
3
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 7, 2023 · Synced Sep 2, 2026, 7:41 PM EDT
Active, not recruiting Phase 3 Interventional

A Research Study to Look at How Well CagriSema Helps People Living With Obesity Lose Weight and Maintain Weight Loss in the Long-term

NCT07011667
View directory record Official record
Conditions
Obesity
Interventions
CagriSema (Cagrilintide B and Semaglutide I), Placebo matched to CagriSema (Cagrilintide B and Semaglutide I)
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
609 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
46
States / cities
Costa Mesa, California • San Diego, California • Walnut Creek, California + 41 more
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Sep 2, 2026, 7:41 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Pilot Study on Weight Loss With Robotic Assistance

NCT03314415
View directory record Official record
Conditions
Overweight and Obesity, Weight Loss
Interventions
Aldebaraan Nao H25
Device
Lead sponsor
Tufts University
Other
Eligibility
25 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 6, 2018 · Synced Sep 2, 2026, 7:41 PM EDT
Completed Not applicable Interventional Results available

The Healthy Moms Study: Comparison of a Post-Partum Weight Loss Intervention Delivered Via Facebook or In-Person Groups

NCT03700736
View directory record Official record
Conditions
Weight Loss, Diet Modification, Physical Activity
Interventions
Healthy Moms
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years and older · Female only
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 22, 2021 · Synced Sep 2, 2026, 7:41 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The ADAPT Trial: Adapting Evidence-Based Obesity Interventions in Community Settings

NCT06546696
View directory record Official record
Conditions
Childhood Obesity
Interventions
Competency Based Approaches to Community Health (COACH)
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
6 Years to 12 Years
Enrollment
750 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Sep 2, 2026, 7:41 PM EDT
Completed Not applicable Interventional

Measuring Eating, Activity and Strength: Understanding the Response -Using Protein

NCT01715753
View directory record Official record
Conditions
Weight Loss
Interventions
Protein supplementation, Diet counseling and group education lessons
Dietary Supplement · Behavioral
Lead sponsor
Duke University
Other
Eligibility
60 Years and older
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 11, 2018 · Synced Sep 2, 2026, 7:41 PM EDT
Completed No phase listed Observational

Pragmatic Weight Loss Intervention During Menopause

NCT04487782
View directory record Official record
Conditions
Menopause, Menopause Related Conditions
Interventions
Focus Groups
Other
Lead sponsor
Kara Marlatt
Other
Eligibility
45 Years to 60 Years · Female only
Enrollment
55 participants
Timeline
2020 – 2021
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Nov 15, 2022 · Synced Sep 2, 2026, 7:41 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Evaluating the Effects of a Diet and Exercise Program in People With Type 2 Diabetes or Prediabetes: (The SHAPE3 Study)

NCT00928005
View directory record Official record
Conditions
Overweight, Obesity, Type 2 Diabetes, Prediabetes
Interventions
Weight loss diet, Weight loss diet plus exercise
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
30 Years to 65 Years
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 3, 2013 · Synced Sep 2, 2026, 7:41 PM EDT
Completed Not applicable Interventional Results available

Effectiveness and Cost-Effectiveness of Fully-Automated Digital vs. Human Coach-Based Diabetes Prevention Programs

NCT05056376
View directory record Official record
Conditions
PreDiabetes, Hyperglycemia, Glucose, High Blood, Overweight, Prediabetic State, Impaired Glucose Tolerance, Obesity, Weight Loss, Lifestyle, Healthy, Lifestyle Risk Reduction, Lifestyle, Sedentary
Interventions
Digital Diabetes Prevention Program (dDPP), Human Coach-based Diabetes Prevention Program (hDPP)
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 75 Years
Enrollment
368 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
2
States / cities
Baltimore, Maryland • Reading, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Sep 2, 2026, 7:41 PM EDT