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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Infrared Laser Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Revitalize Cognition: Near Infrared Stimulation in Older Adults

NCT02582593
View directory record Official record
Conditions
Aging
Interventions
MedX 1116 Rehab Console, Sham MedX 1116 Rehab Console
Device
Lead sponsor
University of Florida
Other
Eligibility
62 Years to 99 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2023
U.S. locations
2
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 18, 2025 · Synced Sep 3, 2026, 6:49 AM EDT
Completed Phase 3 Interventional Results available

Neoadjuvant Carboplatin and Vincristine and Standard Local Ophthalmic Therapy in Treating Patients With Intraocular Retinoblastoma

NCT00079417
View directory record Official record
Conditions
Intraocular Retinoblastoma
Interventions
Carboplatin, Cryosurgery, Infrared Laser Therapy, Iodine I-125, Radiation Therapy, Ruthenium Ru-106, Vincristine Sulfate
Drug · Procedure · Radiation
Lead sponsor
Children's Oncology Group
Network
Eligibility
Up to 5 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2017
U.S. locations
10
States / cities
Los Angeles, California • Chicago, Illinois • Boston, Massachusetts + 6 more
Source: ClinicalTrials.gov public record
Updated Mar 12, 2023 · Synced Sep 3, 2026, 6:49 AM EDT
Not listed Not applicable Interventional

Near-Infrared Laser Stimulation for Various Neurological Conditions

NCT04489082
View directory record Official record
Conditions
Refractory Depression, Anxiety Disorders, Neurodegenerative Diseases, Traumatic Brain Injury, Chronic Traumatic Encephalopathy
Interventions
Near Infrared Laser Stimulation
Device
Lead sponsor
Neurological Associates of West Los Angeles
Other
Eligibility
18 Years and older · Female only
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Sep 27, 2022 · Synced Sep 3, 2026, 6:49 AM EDT
Recruiting Not applicable Interventional

2910 nm Erbium-Doped Fluoride Fiber Glass Laser for the Treatment of Advanced Perioral Lines and Wrinkles

NCT07222397
View directory record Official record
Conditions
Photodamaged Skin, Rhytids, Lines Skin, Wrinkles and Rhytides
Interventions
Laser Resurfacing
Device
Lead sponsor
FA Corporation
Industry
Eligibility
50 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 28, 2025 · Synced Sep 3, 2026, 6:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Examining the Differential Effects of Photobiomodulation on Sleep and Performance

NCT05116605
View directory record Official record
Conditions
Sleep Quality
Interventions
Photobiomodulation (PBM)
Other
Lead sponsor
West Virginia University
Other
Eligibility
18 Years to 50 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Apr 24, 2025 · Synced Sep 3, 2026, 6:49 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Photobiomodulation and Tooth Analgesia

NCT06691269
View directory record Official record
Conditions
Dental Anaesthesia, Dental Pain, Dental Analgesia
Interventions
Photobiomodulation, Topical Benzocaine, Local Anesthesia
Device · Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
6 Years to 12 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 3, 2026, 6:49 AM EDT
Completed Not applicable Interventional Results available

Photobiomodulation in Autism Spectrum Disorder (ASD)

NCT03724552
View directory record Official record
Conditions
Autism, Autism Spectrum Disorder
Interventions
Transcranial LED Therapy (Participants ages 9-17), Transcranial LED Therapy (Participants ages 18-59)
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
9 Years to 59 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 10, 2024 · Synced Sep 3, 2026, 6:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Clinical Evaluation of M22 ResurFX 1565nm Module

NCT01796626
View directory record Official record
Conditions
Wrinkles, Striae
Interventions
M22 ResurFX module
Device
Lead sponsor
Lumenis Be Ltd.
Industry
Eligibility
25 Years to 55 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
2
States / cities
San Diego, California • New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 25, 2014 · Synced Sep 3, 2026, 6:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Intervention With Near Infrared Stimulation

NCT03551392
View directory record Official record
Conditions
Aging
Interventions
Medx Console System, Sham Medx Console System, Vielight 810 intranasal stand alone unit, Sham Vielight 810 intranasal stand alone unit
Device
Lead sponsor
University of Florida
Other
Eligibility
65 Years to 89 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
2
States / cities
Tucson, Arizona • Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Sep 3, 2026, 6:49 AM EDT
Completed No phase listed Observational Results available

Assessment of Blood Vessel Density in Kaposi's Sarcoma Lesions

NCT00026793
View directory record Official record
Conditions
Kaposi's Sarcoma
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years to 100 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2017
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 7, 2020 · Synced Sep 3, 2026, 6:49 AM EDT
Completed Not applicable Interventional Results available

Transcranial Laser Therapy for Major Depressive Disorder

NCT01538199
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Near-infrared radiation via Transcranial LED Therapy, Sham device
Device
Lead sponsor
Paolo Cassano
Other
Eligibility
18 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Boston, Massachusetts • Chelsea, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 28, 2017 · Synced Sep 3, 2026, 6:49 AM EDT
Completed Not applicable Interventional Results available

Evaluating Impact of NIRAF Detection for Identifying Parathyroid Glands During Parathyroidectomy

NCT04299425
View directory record Official record
Conditions
Parathyroid Adenoma, Parathyroid Neoplasms, Parathyroid Hyperplasia, Parathyroid Cancer, Hypercalcemia, Primary Hyperparathyroidism
Interventions
NIRAF Detection Technology
Device
Lead sponsor
Vanderbilt-Ingram Cancer Center
Other
Eligibility
18 Years to 99 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 12, 2024 · Synced Sep 3, 2026, 6:49 AM EDT
Active, not recruiting Phase 3 Interventional

A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma

NCT06007690
View directory record Official record
Conditions
Choroidal Melanoma, Indeterminate Lesions, Uveal Melanoma, Ocular Melanoma
Interventions
Bel-sar, Suprachoroidal Microinjector, Infrared Laser, Sham Infrared Laser, Sham Microinjector
Drug · Device
Lead sponsor
Aura Biosciences
Industry
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
32
States / cities
La Jolla, California • Los Angeles, California • Palo Alto, California + 27 more
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Sep 3, 2026, 6:49 AM EDT
Completed Not applicable Interventional Results available

Volumetric Laser Endomicroscopy With Intelligent Real-time Image Segmentation (IRIS)

NCT03814824
View directory record Official record
Conditions
Barrett's Esophagus Without Dysplasia, Barrett's Esophagus With Dysplasia, Barrett's Esophagus With Low Grade Dysplasia, Barrett's Esophagus With High Grade Dysplasia, Barrett's Esophagus With Dysplasia, Unspecified
Interventions
IRIS (Intelligent real-time image segmentation), VLE (Volumetric laser endomicroscopy)
Diagnostic Test
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
3
States / cities
Scottsdale, Arizona • Rochester, Minnesota • Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Oct 6, 2022 · Synced Sep 3, 2026, 6:49 AM EDT
Completed Not applicable Interventional Results available

Assessing Benefits of NIRAF Detection for Identifying Parathyroid Glands During Total Thyroidectomy.

NCT04281875
View directory record Official record
Conditions
Postoperative Hypoparathyroidism, Thyroid Neoplasms, Thyroid Cancer
Interventions
NIRAF Detection Technology
Device
Lead sponsor
Vanderbilt-Ingram Cancer Center
Other
Eligibility
18 Years to 99 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 16, 2024 · Synced Sep 3, 2026, 6:49 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effect of LASER Photobiomodulation Therapy on Chronic Pain and Opioid Weaning

NCT03437967
View directory record Official record
Conditions
Chronic Pain
Interventions
LightForce EXPi
Device
Lead sponsor
LiteCure LLC
Industry
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 25, 2019 · Synced Sep 3, 2026, 6:49 AM EDT
Completed Phase 2Phase 3 Interventional

Infrared Non-Cutting Laser Therapy for Acne

NCT00110643
View directory record Official record
Conditions
Acne Vulgaris
Interventions
CoolTouch II laser
Device
Lead sponsor
University of Michigan
Other
Eligibility
13 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 3, 2015 · Synced Sep 3, 2026, 6:49 AM EDT
Completed No phase listed Observational

Refractive and Visual Outcomes With the ARGOS Biometer In Eyes With a History of Refractive Surgery: ARGOS Study

NCT07129980
View directory record Official record
Conditions
Cataract
Interventions
ARGOS Biometer
Device
Lead sponsor
Vance Thompson Vision
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated Aug 23, 2025 · Synced Sep 3, 2026, 6:49 AM EDT
Recruiting Not applicable Interventional

Infrared Photobiomodulation in Humans With Epilepsy

NCT07145489
View directory record Official record
Conditions
Drug Resistant Epilepsy
Interventions
photobiomodulation
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Sep 3, 2026, 6:49 AM EDT
Completed Phase 2 Interventional

Vaginal Photobiomodulation for Chronic Pelvic Pain

NCT06673108
View directory record Official record
Conditions
Chronic Pelvic Pain, Chronic Pelvic Pain Syndrome (CPPS)
Interventions
SoLa Pelvic Therapy, Sham
Device
Lead sponsor
SoLa Pelvic Therapy
Industry
Eligibility
18 Years and older · Female only
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
11
States / cities
Birmingham, Alabama • Newport Beach, California • San Francisco, California + 8 more
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Sep 3, 2026, 6:49 AM EDT
Not yet recruiting Phase 1 Interventional

Nanopulse Laser Therapy

NCT07520383
View directory record Official record
Conditions
TBI (Traumatic Brain Injury)
Interventions
Nano-Pulsed Laser Therapy (NPLT)
Device
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 3, 2026, 6:49 AM EDT
Terminated Not applicable Interventional Results available

Personalized Interactive Laser Therapy of Port Wine Stain

NCT00782483
View directory record Official record
Conditions
Port Wine Stain
Interventions
ThermoVision A20M Infrared Camera, ScleroPLUS, 3D Digital Camera
Device
Lead sponsor
University of Arkansas
Other
Eligibility
3 Months to 17 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jul 20, 2014 · Synced Sep 3, 2026, 6:49 AM EDT
Completed No phase listed Observational

Clinical Evaluation of the OtoSight

NCT03890107
View directory record Official record
Conditions
Otitis Media
Interventions
OtoSight Middle Ear Scope
Device
Lead sponsor
PhotoniCare, Inc.
Industry
Eligibility
Up to 17 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated May 21, 2023 · Synced Sep 3, 2026, 6:49 AM EDT
Terminated Not applicable Interventional

Transcranial Pulse Near-Infrared Light in Generalized Anxiety Disorder: a Placebo-Controlled Study

NCT03420456
View directory record Official record
Conditions
Generalized Anxiety Disorder
Interventions
Transcranial Light Therapy
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 4, 2020 · Synced Sep 3, 2026, 6:49 AM EDT