- Conditions
- Respiratory Failure, Infant, Persistent Fetal Circulation
- Interventions
- inhaled Nitric Oxide, Oxygen (>90% by hood) - standard therapy
- Drug
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 1 Hour to 1 Week
- Enrollment
- 8 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1999 – 2005
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–23
of 23
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Infant, Newborn, Hypertension, Pulmonary, Persistent Fetal Circulation Syndrome, Pneumonia, Aspiration, Respiratory Distress Syndrome, Newborn, Respiratory Insufficiency
- Interventions
- Inhaled Nitric Oxide, Standard iNO therapy
- Drug
- Lead sponsor
- NICHD Neonatal Research Network
- Network
- Eligibility
- Up to 14 Days
- Enrollment
- 302 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1998 – 2003
- U.S. locations
- 18
- States / cities
- Birmingham, Alabama • Phoenix, Arizona • Palo Alto, California + 14 more
- Conditions
- Lung Diseases, Bronchopulmonary Dysplasia
- Interventions
- iNO, Placebo
- Drug · Other
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- Up to 1 Year
- Enrollment
- 793 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2000 – 2007
- U.S. locations
- 14
- States / cities
- Phoenix, Arizona • Loma Linda, California • Los Angeles, California + 11 more
- Conditions
- Pulmonary Embolism, Pulmonary Embolism Subacute Massive
- Interventions
- inhaled nitric oxide (iNO)
- Drug
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Acute Kidney Injury
- Interventions
- Nitric Oxide, Placebo
- Drug · Other
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 250 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2025
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Pulmonary Hypertension, Bronchopulmonary Dysplasia
- Interventions
- inhaled nitric oxide, Placebo
- Drug
- Lead sponsor
- AdventHealth
- Other
- Eligibility
- 23 Weeks to 29 Weeks
- Enrollment
- 32 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2023
- U.S. locations
- 1
- States / cities
- Orlando, Florida
- Conditions
- COVID-19
- Interventions
- Nitric Oxide
- Drug
- Lead sponsor
- Tufts Medical Center
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Acute Respiratory Distress Syndrome, Ventilation Perfusion Mismatch
- Interventions
- Nitric Oxide
- Device
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 70 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Respiratory Distress Syndrome in Premature Infants, Very Low Birth Weight Baby
- Interventions
- iNO, Nitrogen
- Drug · Other
- Lead sponsor
- University of Oklahoma
- Other
- Eligibility
- 1 Minute to 2 Minutes
- Enrollment
- 33 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2017
- U.S. locations
- 2
- States / cities
- Oklahoma City, Oklahoma
- Conditions
- Reperfusion Injury, Liver Injury
- Interventions
- inhaled nitric oxide, nitrogen gas
- Drug
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 19 Years to 80 Years
- Enrollment
- 80 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2012
- U.S. locations
- 2
- States / cities
- Birmingham, Alabama • Seattle, Washington
- Conditions
- Hypertension, Pulmonary, Lung Diseases, Interstitial
- Interventions
- Inhaled Nitric Oxide (iNO)
- Device
- Lead sponsor
- Third Pole Therapeutics, Inc.
- Industry
- Eligibility
- 22 Years to 84 Years
- Enrollment
- 5 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 3
- States / cities
- Tampa, Florida • Cincinnati, Ohio • Charleston, South Carolina
- Conditions
- Blood Transfusion, Endothelial Physiopathology, Nitric Oxide, Pulmonary Hypertension
- Interventions
- Red blood Cells auto-transfusion, Inhaled Nitric Oxide (iNO) administration
- Procedure · Drug
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2013
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Pulmonary Arterial Hypertension
- Interventions
- Inhaled Nitric Oxide 75 mcg/kg IBW/hr, Placebo
- Drug
- Lead sponsor
- Bellerophon Pulse Technologies
- Industry
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 207 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 37
- States / cities
- Phoenix, Arizona • Tucson, Arizona • Beverly Hills, California + 33 more
- Conditions
- Prematurity, Bronchopulmonary Dysplasia, Intraventricular Hemorrhage, Periventricular Leukomalacia
- Interventions
- inhaled nitric oxide, oxygen
- Drug
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 2 Hours to 72 Hours
- Enrollment
- 273 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2023
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Pulmonary Arterial Hypertension
- Interventions
- Nitric Oxide
- Drug
- Lead sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Respiratory Distress Syndrome of Prematurity (Surfactant Dysfunction), Bronchopulmonary Dysplasia
- Interventions
- Infasurf (ONY Inc.), Sham
- Drug
- Lead sponsor
- Roberta Ballard
- Other
- Eligibility
- 7 Days to 14 Days
- Enrollment
- 85 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2012
- U.S. locations
- 9
- States / cities
- Berkeley, California • Oakland, California • San Francisco, California + 5 more
- Conditions
- COVID-19, Hypoxemia, Hypoxemic Respiratory Failure
- Interventions
- Inhaled nitric oxide (iNO), Nitrogen gas, Oxygen gas
- Drug
- Lead sponsor
- Roger Alvarez
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Bronchopulmonary Dysplasia
- Interventions
- Infasurf surfactant (ONY, Inc.), Sham (No Treatment)
- Drug
- Lead sponsor
- Roberta Ballard
- Other
- Eligibility
- 7 Days to 14 Days
- Enrollment
- 511 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2016
- U.S. locations
- 21
- States / cities
- Little Rock, Arkansas • Berkeley, California • Oakland, California + 15 more
- Conditions
- Endothelial Dysfunction, Hemolysis Intravascular, Cardiovascular Diseases, Cardiovascular Risk Factor
- Interventions
- Nitric Oxide, Reactive Hyperemia Index, Endothelial Cells Collection
- Drug · Diagnostic Test · Procedure
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2023
- U.S. locations
- 2
- States / cities
- Boston, Massachusetts
- Conditions
- Anemia, Sickle Cell
- Interventions
- Nitric Oxide, Placebo
- Drug
- Lead sponsor
- Mallinckrodt
- Industry
- Eligibility
- 10 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2008
- U.S. locations
- 11
- States / cities
- Birmingham, Alabama • Oakland, California • Aurora, Colorado + 7 more
- Conditions
- Cardiovascular Diseases, Oxidative Stress, Endothelial Dysfunction
- Interventions
- Nitrogen Gas for Inhalation, Blood withdrawal, Nitric Oxide
- Drug · Other
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2025
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Pulmonary Arterial Hypertension
- Interventions
- Placebo, iNO
- Drug
- Lead sponsor
- Bellerophon Pulse Technologies
- Industry
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2020
- U.S. locations
- 2
- States / cities
- Chicago, Illinois • Charleston, South Carolina
- Conditions
- Corona Virus Infection, COVID-19, SARS-CoV 2, Nitric Oxide, Respiratory Disease, Pneumonia, Viral, Inhaled Nitric Oxide
- Interventions
- Nitric Oxide delivered via LungFit™ system
- Device
- Lead sponsor
- Beyond Air Inc.
- Industry
- Eligibility
- 22 Years to 65 Years
- Enrollment
- 4 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020
- U.S. locations
- 1
- States / cities
- Little Rock, Arkansas