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ClinicalTrials.gov public records Last synced Oct 20, 2026, 6:14 PM EDT

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Showing 1–24 of 107 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Insufflation Clear all
Completed No phase listed Observational

Echo Detection of Endoscopic Retrograde Cholangiopancreatography (ERCP) Air Embolus

NCT01535248
View directory record Official record
Conditions
Air Embolism as A Complication of Medical Care
Interventions
Transthoracic Echocardiography
Other
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 6, 2023 · Synced Oct 20, 2026, 6:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Trendelenburg, Abdominal Insufflation and Time to Completion of Cystoscopy

NCT05786391
View directory record Official record
Conditions
Bladder Integrity, Bladder Function, Ureteral Integrity, Ureteral Function
Interventions
Flat position, Trendelenburg position, Insufflation
Other · Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 24, 2025 · Synced Oct 20, 2026, 6:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

THRIVE Use in Pediatric Populations- Multi Site

NCT04322994
View directory record Official record
Conditions
Oxygen Deficiency, Desaturation of Blood, Hypoventilation, Anesthesia; Adverse Effect
Interventions
Transnasal Humidified Rapid-Insufflation Ventilatory Echange
Device
Lead sponsor
Stanford University
Other
Eligibility
Up to 18 Years
Enrollment
175 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
5
States / cities
Palo Alto, California • Chicago, Illinois • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 27, 2025 · Synced Oct 20, 2026, 6:14 PM EDT
Completed Not applicable Interventional

Comparing the Adenoma Detection Rate With Air Insufflation, Water Immersion and Water Exchange

NCT01894191
View directory record Official record
Conditions
Adenoma
Interventions
Air insufflation, water immersion, Water exchange
Procedure
Lead sponsor
Dalin Tzu Chi General Hospital
Other
Eligibility
20 Years to 80 Years
Enrollment
651 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
North Hills, California
Source: ClinicalTrials.gov public record
Updated Jun 28, 2016 · Synced Oct 20, 2026, 6:14 PM EDT
Withdrawn Not applicable Interventional

Pain After Insufflation for Robotic Sacrocolpopexy (PAIRS) Trial

NCT04858438
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Insufflation during surgery
Procedure
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 90 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 20, 2026, 6:14 PM EDT
Withdrawn Not applicable Interventional

Transoral Gastric Volume Reduction as an Intervention for Weight Management

NCT02578836
View directory record Official record
Conditions
Obesity, Overweight, Weight Loss
Interventions
Fogel Gastroplasty
Procedure
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 60 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 31, 2017 · Synced Oct 20, 2026, 6:14 PM EDT
Not listed Not applicable Interventional

SurgiQuest AirSeal in Robotic Partial Nephrectomy - (TARPAN Study)

NCT02262884
View directory record Official record
Conditions
Subcutaneous Emphysema
Interventions
SurgiQuest AirSeal Insufflation System (AIS), Conventional Insufflation System (CIS)
Device
Lead sponsor
SurgiQuest, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
189 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
3
States / cities
St Louis, Missouri • Hackensack, New Jersey • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 6, 2016 · Synced Oct 20, 2026, 6:14 PM EDT
Completed Not applicable Interventional

A Trial of Supplemental CO2 Versus Room Air in Percutaneous Endoscopic Gastrostomy

NCT02619656
View directory record Official record
Conditions
Pneumoperitoneum
Interventions
CO2 insufflation, Ambient air insufflation
Procedure
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Dec 2, 2015 · Synced Oct 20, 2026, 6:14 PM EDT
Terminated Phase 3 Interventional Accepts healthy volunteers

Comparison of Adenoma Detection Rate Among Water, Carbon Dioxide and Air Methods of Minimal Sedation Colonoscopy

NCT01782014
View directory record Official record
Conditions
Screening Colonoscopy
Interventions
colonoscopy
Procedure
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 80 Years
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Feb 1, 2016 · Synced Oct 20, 2026, 6:14 PM EDT
Completed Phase 2 Interventional Results available

Metoclopramide Versus Placebo for GJ Placement

NCT03331965
View directory record Official record
Conditions
Radiation Exposure, Enteral Nutrition
Interventions
Metoclopramide 5 MG/ML Injectable Solution, Saline
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 13, 2020 · Synced Oct 20, 2026, 6:14 PM EDT
Completed Not applicable Interventional

Randomized Controlled Trial Comparing Water vs. Air Method for Performing Colonoscopy in Adult Female Subjects

NCT01790425
View directory record Official record
Conditions
Screening for Colon Cancer
Interventions
to infuse water into colon to open the lumen for water infusion colonoscopy, Air colonoscopy
Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 27, 2017 · Synced Oct 20, 2026, 6:14 PM EDT
Completed Not applicable Interventional Results available

Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) and Diagnostic Bronchoscopy

NCT03086408
View directory record Official record
Conditions
Bronchoscopy
Interventions
THRIVE, Endotracheal tube or Supraglottic airway
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jul 17, 2020 · Synced Oct 20, 2026, 6:14 PM EDT
Completed Not applicable Interventional Results available

A Comparative Study Between AirSeal, an Integrated Insufflation System, and Conventional Insufflation

NCT02075658
View directory record Official record
Conditions
Renal Cell Carcinoma
Interventions
AirSeal® System-Interventional, Conventional Insufflator and Trocar
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2014
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Feb 14, 2018 · Synced Oct 20, 2026, 6:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Stabilization of Hypercapnia: NIPPV v HVNI

NCT04709562
View directory record Official record
Conditions
Hypercapnic Respiratory Failure, Chronic Obstructive Pulmonary Disease, Dyspnea, Hypercapnic Acidosis
Interventions
High Velocity Nasal Insufflation (HVNI), Noninvasive Positive Pressure Ventilation (NIPPV)
Device
Lead sponsor
Vapotherm, Inc.
Industry
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
7
States / cities
Los Angeles, California • Oxnard, California • Washington D.C., District of Columbia + 4 more
Source: ClinicalTrials.gov public record
Updated Aug 9, 2024 · Synced Oct 20, 2026, 6:14 PM EDT
Completed Not applicable Interventional

Comparing the ADR With Air Insufflation, Water Immersion and Water Exchange During Two-endoscopist Colonoscopy

NCT02737514
View directory record Official record
Conditions
Adenoma
Interventions
Air insufflation, water immersion, water exchange
Procedure
Lead sponsor
Dalin Tzu Chi General Hospital
Other
Eligibility
20 Years to 80 Years
Enrollment
371 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
North Hills, California
Source: ClinicalTrials.gov public record
Updated May 29, 2020 · Synced Oct 20, 2026, 6:14 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Comparative Efficacy of Water & Indigo Carmine vs. Water or Air Method on Adenoma Detection Rate (ADR) - a Randomized Controlled Trial (RCT)

NCT01607255
View directory record Official record
Conditions
Colorectal Neoplasms
Interventions
Indigo carmine, water (exchange) method, water (exchange) plus dye method, air method
Drug · Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
45 Years to 75 Years
Enrollment
480 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jan 15, 2019 · Synced Oct 20, 2026, 6:14 PM EDT
Completed Not applicable Interventional

Pneumoperitoneum Management With SurgiQuest AirSeal at Low vs. Higher Pressure ( PRESSURE )

NCT02541448
View directory record Official record
Conditions
Shoulder Pain
Interventions
SurgiQuest AIRSEAL® Insufflation System (AIS)
Device
Lead sponsor
Cynthia Harris
Industry
Eligibility
18 Years to 80 Years
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Nov 13, 2019 · Synced Oct 20, 2026, 6:14 PM EDT
Active, not recruiting Not applicable Interventional Results available

Fetoscopic NEOX Cord 1K® Spina Bifida Repair

NCT04243889
View directory record Official record
Conditions
Spina Bifida, Myelomeningocele, Myeloschisis
Interventions
NEOX Cord 1K
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2029
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 20, 2026, 6:14 PM EDT
Completed No phase listed Observational

Trans Nasal Insufflation for the Treatment of Snoring

NCT00832026
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Trans Nasal Insufflation (TNI) [nasal canula]
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 12, 2023 · Synced Oct 20, 2026, 6:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Colon Capsule Endoscopy (CCE) Versus Computed Tomographic Colonography (CTC) in the Identification of Colonic Polyps in a Screening Population.

NCT02754661
View directory record Official record
Conditions
Colorectal Cancer Screening
Interventions
COLON Capsule endoscopy, Computed Tomographic Colonography
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
50 Years to 75 Years
Enrollment
320 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
13
States / cities
Mobile, Alabama • Jacksonville, Florida • Chicago, Illinois + 8 more
Source: ClinicalTrials.gov public record
Updated Oct 1, 2019 · Synced Oct 20, 2026, 6:14 PM EDT
Completed Not applicable Interventional

Unsedated Colonoscopy for Colorectal Cancer Screening and Surveillance

NCT01383252
View directory record Official record
Conditions
Colon Polyp
Interventions
Water infusion in lieu of air insufflation, Air method
Procedure
Lead sponsor
VA Northern California Health Care System
Federal
Eligibility
50 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Mather, California
Source: ClinicalTrials.gov public record
Updated Jun 17, 2013 · Synced Oct 20, 2026, 6:14 PM EDT
Completed Not applicable Interventional Results available

Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) and Laser Laryngeal Surgery

NCT03086265
View directory record Official record
Conditions
Otorhinolaryngologic Surgical Procedures, Laser Therapy
Interventions
THRIVE, Endotracheal tube
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Mar 17, 2020 · Synced Oct 20, 2026, 6:14 PM EDT
Recruiting Not applicable Interventional

Safety and Efficacy of Carbon Dioxide Gas for Endoscopy

NCT06134154
View directory record Official record
Conditions
Abdominal Pain
Interventions
Endoscopic insufflation gas
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
6 Months to 18 Years
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 23, 2026 · Synced Oct 20, 2026, 6:14 PM EDT
Completed Phase 4 Interventional Results available

Safety and Efficacy of CO2 for Endoscopy

NCT03287687
View directory record Official record
Conditions
Endoscopy, Insufflation
Interventions
Carbon dioxide (CO2) gas insufflation, Air insufflation
Drug
Lead sponsor
Warren Bishop
Other
Eligibility
6 Months to 21 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jan 19, 2022 · Synced Oct 20, 2026, 6:14 PM EDT