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ClinicalTrials.gov public records Last synced Nov 15, 2026, 7:26 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 114 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Intensive lifestyle Intervention Clear all

Conditions: Diabetes Mellitus, Type 2, HIV Infections, PreDiabetes
Interventions: MTM + ILI, Standard MTM; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: PreDiabetes
Interventions: NDPP-Flex, NDPP; Behavioral
Lead sponsor: Denver Health and Hospital Authority; Other
Eligibility: 18 Years to 85 Years · Female only
Enrollment: 214 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Type 2 Diabetes
Interventions: Intensive lifestyle interventions (ILIs); Behavioral
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older · Male only
Enrollment: 108 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Dunwoody, Georgia

Conditions: Hypertension, Physical Activity, Diet, Medication Adherence
Interventions: Therapeutic Lifestyle Changes (MINT-TLC), Usual Care; Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older
Enrollment: 194 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 4
States / cities: Brooklyn, New York • New York, New York

Conditions: Obesity
Interventions: Diabetes Prevention Program Intensive Lifestyle Intervention plus stress management training, Diabetes Prevention Program Intensive Lifestyle Intervention plus general women's health topics; Behavioral
Lead sponsor: H. Lee Moffitt Cancer Center and Research Institute; Other
Eligibility: 21 Years to 75 Years · Female only
Enrollment: 341 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Breast Cancer, Obesity
Interventions: Survivors RESET; Behavioral
Lead sponsor: H. Lee Moffitt Cancer Center and Research Institute; Other
Eligibility: 18 Years and older · Female only
Enrollment: 37 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Hypertension
Interventions: Motivational interviewing (MINT-TLC); Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older
Enrollment: 373 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: New York, New York

Conditions: Overweight, Weight Loss
Interventions: H.E.A.L.T.H. II Intervention; Behavioral
Lead sponsor: Pennington Biomedical Research Center; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Baton Rouge, Louisiana

Conditions: Overweight, Obese
Interventions: Steps to Health, Steps to Health Plus!; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 550 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Diabetes Mellitus, Hyperglycemia, Obesity, Glucose Metabolism Disorders, Metabolic Diseases, Endocrine System Diseases, Overnutrition, Nutrition Disorders, Overweight, Body Weight, Signs and Symptoms
Interventions: Standard Lifestyle Advice, Advice Plus Lifestyle Intervention; Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 331 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 2
States / cities: Chicago, Illinois • Evanston, Illinois

Conditions: Coronary Artery Disease
Interventions: High dose potent statin, ACE-I (lisinopril) or ARB (losartan), Aspirin 81 enteric coated tablet daily, Lifestyle Counseling, Quality of Life Questionnaires; Drug · Behavioral
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 18 Years to 100 Years · Female only
Enrollment: 2,476 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2027
U.S. locations: 80
States / cities: Mobile, Alabama • Gilbert, Arizona • Phoenix, Arizona + 54 more

Conditions: Obesity, Pregnancy
Interventions: Dietary and lifestyle counseling; Behavioral
Lead sponsor: Carolinas Medical Center; Other
Eligibility: 18 Years to 49 Years · Female only
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2007
U.S. locations: 1
States / cities: Charlotte, North Carolina

Conditions: Migraine, Obesity
Interventions: Behavioral Weight Loss Intervention, Migraine Education; Behavioral · Other
Lead sponsor: The Miriam Hospital; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 112 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2017
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Alcohol Dependence
Interventions: LPA+Fitbit, HEC; Behavioral
Lead sponsor: Butler Hospital; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Overweight, Type 2 Diabetes Mellitus, Type 1 Diabetes Mellitus
Interventions: Lifestyle Intervention, No Intervention; Other
Lead sponsor: Joslin Diabetes Center; Other
Eligibility: 18 Years to 65 Years · Male only
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2026
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Osteoarthritis, Cardiovascular Disease
Interventions: Metoprolol, Lisinopril, Atorvastatin, Lifestyle counseling; Drug · Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: 21 Years and older
Enrollment: 198 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: New York, New York

Conditions: Lifestyle Risk Reduction, Adolescent Health, Family Health, Cardio-metabolic Health, Mental Health, Wellness Program, Type 2 Diabetes, Obesity, Adolescent
Interventions: Mindfulness-Based Intervention, Parent Education, Physical Activity, Brief Mindfulness Intervention for Parents, Preschool Curriculum, Nutrition and Cooking Education; Behavioral
Lead sponsor: Colorado State University; Other
Eligibility: 11 Years and older
Enrollment: 140 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Fort Collins, Colorado

Conditions: Pediatric Obesity
Interventions: Not listed
Lead sponsor: Duke University; Other
Eligibility: 10 Years to 18 Years
Enrollment: 295 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Obesity, Diabetes Mellitus, Type 2
Interventions: Meal replacement system, Intensive lifestyle Intervention; Dietary Supplement · Behavioral
Lead sponsor: Loma Linda University; Other
Eligibility: 25 Years to 65 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Loma Linda, California

Conditions: Prediabetic State, Obesity, Gestational Diabetes
Interventions: Presessions, National Diabetes Prevention Program; Behavioral
Lead sponsor: Denver Health and Hospital Authority; Other
Eligibility: 18 Years and older
Enrollment: 483 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Type 2 Diabetes
Interventions: Roux-en-Y Gastric Bypass surgery, Laparoscopic Adjustable Gastric Banding surgery, Intensive Lifestyle Modification; Procedure · Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 65 Years
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2015
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Breast Cancer, Cardiotoxicity
Interventions: antihypertensive medications, Blood pressure measurement, Echocardiogram, Symptom-limited cardiopulmonary exercise test, Quality of Life Measures, Biomarkers; Other · Diagnostic Test
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 130 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2029
U.S. locations: 7
States / cities: Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more

Conditions: Obesity, Diabetes
Interventions: Intensive lifestyle, Standard intervention; Behavioral
Lead sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); NIH
Eligibility: 7 Years to 12 Years
Enrollment: 360 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Recurrent Prostate Cancer, Stage IV Prostate Cancer
Interventions: behavioral dietary intervention, exercise intervention, behavioral activity counseling, telephone based counseling, quality-of-life assessment, questionnaire administration; Behavioral · Other · Procedure
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: Male only
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Columbus, Ohio

Search by objective public record fields.

Food as Medicine for HIV and Diabetes

Patient-centered Goal Setting in the National Diabetes Prevention Program

Better Together Study

Practice-based Trial of Blood Pressure Control in African Americans

Reducing Weight and Elevated Stress Levels Using Educational and Behavioral Tools

Breast Cancer Survivors RESET (Reducing Weight and Elevated Stress Levels Using Educational and Behavioral Tools): A Pilot, Feasibility Study

Faith-based Approaches in the Treatment of Hypertension (FAITH)

Healthy Eating, Activity, & Lifestyle Training Headquarters: II Pilot Project

Steps to Health: Targeting Obesity in the Health Care Workplace

Intervening in Diabetes With Healthy Eating, Activity, and Linkages To Healthcare - The I-D-HEALTH Study

Women's IschemiA TRial to Reduce Events In Non-ObstRuctive CAD

Does Dietary and Lifestyle Counseling Prevent Excessive Weight Gain During Pregnancy? A Randomized Controlled Trial

Behavioral Weight Loss as a Treatment for Migraine in Obese Women

Lifestyle Physical Activity Intervention for Depressed Alcohol Dependent Women

Impact of Metabolic Health on Sperm Epigenetic Marks in Humans

Risk Factor Control Before Orthopedic Surgery

Health Without Barriers/Salud Sin Barreras- Northern Colorado

Pediatric Obesity Observational Prospective Trial

Weight Management for the Remission of Type 2 Diabetes Using a Proprietary Meal Replacement System- Diabetes Remission Study (DRS)

Presessions for the National Diabetes Prevention Program

Surgery Or Lifestyle Intervention for Type 2 Diabetes (SOLID)

A Study of Blood Pressure Control During Cancer Treatment

Family Weight Management Study

Intensive Diet and Exercise or Standard of Care in Improving Physical Function and Quality of Life in Patients With Prostate Cancer Undergoing Androgen Deprivation Therapy