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Showing 1–24 of 86 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Intensive lifestyle modification Clear all
Completed Not applicable Interventional Results available

A Virtual Cardiometabolic Health Program for African Immigrants: The Afro-DPP Program

NCT05144737
View directory record Official record
Conditions
Diabetes Mellitus, Diabetes Mellitus, Type 2, PreDiabetes, Hypertension, High Blood Pressure, High Blood Sugar, Obesity, Overweight, Overweight and Obesity, Overweight or Obesity
Interventions
The Diabetes Prevention Program
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
25 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Sep 2, 2026, 10:55 AM EDT
Enrolling by invitation Not applicable Interventional

Evaluation of a Primary Care Based Lifestyle Medicine Clinic at UAB

NCT06989281
View directory record Official record
Conditions
Obesity and Obesity-related Medical Conditions
Interventions
FLOW Lifestyle Medicine Clinic
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 89 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 2, 2026, 10:55 AM EDT
Completed Not applicable Interventional Results available

Changing Lifestyles for Better Health

NCT00848757
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Intensive Lifestyle Intervention
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 3, 2022 · Synced Sep 2, 2026, 10:55 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Does Dietary and Lifestyle Counseling Prevent Excessive Weight Gain During Pregnancy? A Randomized Controlled Trial

NCT00792480
View directory record Official record
Conditions
Obesity, Pregnancy
Interventions
Dietary and lifestyle counseling
Behavioral
Lead sponsor
Carolinas Medical Center
Other
Eligibility
18 Years to 49 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 17, 2008 · Synced Sep 2, 2026, 10:55 AM EDT
Completed Not applicable Interventional

Implementation of Multifaceted Patient-Centered Treatment Strategies for Intensive Blood Pressure Control (IMPACTS)

NCT03483662
View directory record Official record
Conditions
Hypertension, Blood Pressure
Interventions
Multicomponent Intervention, Enhanced Usual Care
Behavioral
Lead sponsor
Tulane University
Other
Eligibility
40 Years and older
Enrollment
1,272 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
2
States / cities
New Orleans, Louisiana • Biloxi, Mississippi
Source: ClinicalTrials.gov public record
Updated Jul 8, 2025 · Synced Sep 2, 2026, 10:55 AM EDT
Terminated Not applicable Interventional

Lifestyle Intervention for Rheumatoid Arthritis

NCT05554705
View directory record Official record
Conditions
Lifestyle Risk Reduction, Rheumatoid Arthritis
Interventions
Intensive Lifestyle intervention
Behavioral
Lead sponsor
Blue Cross Blue Shield of Vermont
Other
Eligibility
18 Years and older
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Berlin Corners, Vermont
Source: ClinicalTrials.gov public record
Updated Aug 3, 2023 · Synced Sep 2, 2026, 10:55 AM EDT
Completed Not applicable Interventional Results available

Surgery or Lifestyle With Intensive Medical Management in the Treatment of Type 2 Diabetes

NCT01073020
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Obesity
Interventions
Allergan Adjustable Gastric Band Surgery, Intensive Medical Diabetes & Weight Management (Why WAIT) - Band Group, Roux-en-Y Gastric Bypass (RYGB) Surgery, Intensive Medical Diabetes & Weight Management (Why WAIT) - Bypass Group
Device · Other · Procedure
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
21 Years to 65 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 27, 2021 · Synced Sep 2, 2026, 10:55 AM EDT
Recruiting Not applicable Interventional

Type 1 Diabetes Adolescents for Healthier Lifestyles Study

NCT06878872
View directory record Official record
Conditions
Type 1 Diabetes, Eating Behavior, Adolescent Obesity
Interventions
T1DAL Program
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
13 Years to 18 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Sep 2, 2026, 10:55 AM EDT
Completed Not applicable Interventional

LIFT: Lifestyle Interventions For Two

NCT01616147
View directory record Official record
Conditions
Overweight, Pregnancy
Interventions
Intensive Lifestyle Intervention (ILI), Usual Care
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 31, 2019 · Synced Sep 2, 2026, 10:55 AM EDT
Completed Not applicable Interventional

Buprenorphine and Substance Abuse Services for Prescription Opioid Dependence

NCT02496403
View directory record Official record
Conditions
Opiate Substitution Treatment
Interventions
Standard Medical Management (SMM)
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
239 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Sep 25, 2019 · Synced Sep 2, 2026, 10:55 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Impact of Metabolic Health on Sperm Epigenetic Marks in Humans

NCT03860558
View directory record Official record
Conditions
Overweight, Type 2 Diabetes Mellitus, Type 1 Diabetes Mellitus
Interventions
Lifestyle Intervention, No Intervention
Other
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Sep 2, 2026, 10:55 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Pediatric Obesity Observational Prospective Trial

NCT03139877
View directory record Official record
Conditions
Pediatric Obesity
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
10 Years to 18 Years
Enrollment
295 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 17, 2021 · Synced Sep 2, 2026, 10:55 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Methylation Diet and Lifestyle Study

NCT03472820
View directory record Official record
Conditions
Lifestyle, Diet, Healthy
Interventions
Diet Recommendations, Lifestyle Recommendations, Exercise Recommendations, Stress Management Recommendations, PhytoGanix (tropical fruit flavor), UltraFlora Intensive Care
Other
Lead sponsor
National University of Natural Medicine
Other
Eligibility
50 Years to 72 Years · Male only
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 5, 2024 · Synced Sep 2, 2026, 10:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

PTSC: Improving Hypertension Control Among Poor Midlife African American Women

NCT04371614
View directory record Official record
Conditions
Uncontrolled Hypertension, BMI, Stress, Medication Adherence
Interventions
Prime Time Sister Circle
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
40 Years to 75 Years · Female only
Enrollment
359 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 4, 2022 · Synced Sep 2, 2026, 10:55 AM EDT
Completed Not applicable Interventional

The Healthy Eating and Active Living to Reverse Diabetes Pilot Study

NCT07316569
View directory record Official record
Conditions
Diabete Type 2, Diabetes, Overweight , Obesity
Interventions
Intensive Multicomponent Healthy Eating and Weight Loss Intervention, Enhanced Usual Diabetes Care
Behavioral
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 4, 2026 · Synced Sep 2, 2026, 10:55 AM EDT
Active, not recruiting Not applicable Interventional

NOURISH-T+: Promoting Healthy Eating and Exercise Behaviors

NCT04656496
View directory record Official record
Conditions
Obesity, Childhood, Cancer, Survivorship
Interventions
NOURISH-T+, Brief NOURISH-T+
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
5 Years to 14 Years
Enrollment
520 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
10
States / cities
Washington D.C., District of Columbia • Gainesville, Florida • Miami, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 2, 2026, 10:55 AM EDT
Completed Not applicable Interventional Results available

Lifestyle Intervention for Young Adults With Serious Mental Illness

NCT02815813
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Major Depressive Disorder, Overweight, Obesity
Interventions
PeerFIT, BEAT
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 35 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
2
States / cities
New Britain, Connecticut • Nashua, New Hampshire
Source: ClinicalTrials.gov public record
Updated Jan 13, 2025 · Synced Sep 2, 2026, 10:55 AM EDT
Completed Phase 2 Interventional

Reducing Weight and Diabetes Risk in an Underserved Population (STRIDE)

NCT00790517
View directory record Official record
Conditions
Weight Loss, Diabetes Mellitus, Type 2, Psychotic Disorders
Interventions
Premier Lifestyle Intervention with DASH Diet
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
3
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 16, 2015 · Synced Sep 2, 2026, 10:55 AM EDT
Completed Not applicable Interventional

NC Enhanced WISEWOMAN Project

NCT00288327
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
Lifestyle behavior change program, Pamphlets
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
40 Years to 64 Years · Female only
Enrollment
258 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
Wilmington, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 12, 2009 · Synced Sep 2, 2026, 10:55 AM EDT
Completed Phase 2 Interventional

Lifestyle Intervention to Improve Insulin Sensitivity and Markers of Cardiovascular Risk in Prostate Cancer Survivors

NCT00738140
View directory record Official record
Conditions
Prostate Cancer
Interventions
Diabetes Prevention Program
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older · Male only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
3
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 10, 2013 · Synced Sep 2, 2026, 10:55 AM EDT
Completed Not applicable Interventional

Dissemination and Implementation of the Bright Bodies Intervention for Childhood Obesity

NCT05595161
View directory record Official record
Conditions
Obesity, Childhood
Interventions
Bright Bodies
Behavioral
Lead sponsor
Yale University
Other
Eligibility
7 Years to 13 Years
Enrollment
184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
3
States / cities
Birmingham, Alabama • San Francisco, California • Portland, Maine
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Sep 2, 2026, 10:55 AM EDT
Completed Not applicable Interventional

Steps to Health: Targeting Obesity in the Health Care Workplace

NCT01299051
View directory record Official record
Conditions
Overweight, Obese
Interventions
Steps to Health, Steps to Health Plus!
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
550 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 7, 2016 · Synced Sep 2, 2026, 10:55 AM EDT
Completed Not applicable Interventional

A Comprehensive Community Approach for Diabetes Prevention and Care for a Vulnerable Population in Galveston

NCT05097534
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
iDSMES, Standard of Care
Other
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
13 Years to 84 Years
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Sep 2, 2026, 10:55 AM EDT
Completed Not applicable Interventional

Financial Coaching and Lifestyle Intervention for Diabetes Prevention in Low-income Families

NCT05944549
View directory record Official record
Conditions
Weight Loss
Interventions
Financial coaching using TrustPlus, Brighter Bites, Noom
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 8, 2025 · Synced Sep 2, 2026, 10:55 AM EDT