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ClinicalTrials.gov public records Last synced Oct 1, 2026, 11:31 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 102 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Intensive medical therapy Clear all
Completed Not applicable Interventional

Palliative Care in the ICU

NCT03263143
View directory record Official record
Conditions
Palliative Care
Interventions
Palliative Care
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
242 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 24, 2019 · Synced Oct 1, 2026, 11:31 AM EDT
Recruiting Not applicable Interventional

NT-ProBNP-based Heart Failure Screening and Prevention Trial in Patients With Type 2 Diabetes: STRONG-DM Study

NCT06593327
View directory record Official record
Conditions
Type 2 Diabetes, Diabetic Cardiomyopathy, Heart Failure, Cardiometabolic Diseases
Interventions
Intensive Prevention Strategy
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
Not listed
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
3
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 1, 2026, 11:31 AM EDT
Recruiting Not applicable Interventional

Reestablishing Sleep and Circadian Alignment in Medical Intensive Care Unit (MICU) Patients Via a Mechanistic RCT of an Sleep Chronobundle

NCT05551325
View directory record Official record
Conditions
Critical Illness, Sleep Deprivation, Circadian Rhythm Sleep Disorder, Unspecified
Interventions
Chronobundle - light, chronobundle - feeding, chronobundle - mobility, chronobundle - sleep
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
2
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Oct 1, 2026, 11:31 AM EDT
Not listed Phase 3 Interventional

Effects of Intensive Bolus Intravenous Insulin Delivery on Metabolic Integrity in Type 1 and Type 2 Diabetes

NCT01023165
View directory record Official record
Conditions
Diabetes Mellitus, Metabolic Integrity
Interventions
Humulin, Humalog, Novolog
Procedure
Lead sponsor
Global Infusion and Aspiration Systems, LLC
Other
Eligibility
18 Years to 95 Years
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Batesville, Mississippi
Source: ClinicalTrials.gov public record
Updated Jun 22, 2011 · Synced Oct 1, 2026, 11:31 AM EDT
Active, not recruiting No phase listed Observational

CREST-2 Long-term Observational Extension Study

NCT05465122
View directory record Official record
Conditions
Stenoses, Carotid
Interventions
Carotid Endarterectomy, FDA-approved carotid stents, Intensive Medical Management
Procedure · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
35 Years and older
Enrollment
2,480 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
61
States / cities
Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 51 more
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 1, 2026, 11:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preventing Chronic Depression and PTSD in Stroke Patients Admitted to the Neuroscience Intensive Care Unit (NICU) and Their Family Caregivers

NCT02797509
View directory record Official record
Conditions
Neurological Disorder
Interventions
Psychosocial Skills-Based Intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 17, 2018 · Synced Oct 1, 2026, 11:31 AM EDT
Completed Not applicable Interventional

Intensive Care Program for Youth With Diabetes

NCT00961974
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
Care Ambassador Intervention, Psychoeducational Intervention
Behavioral
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
8 Years to 16 Years
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 4, 2021 · Synced Oct 1, 2026, 11:31 AM EDT
Terminated Not applicable Interventional

Sleeve Gastrectomy Versus Medical Management for Remission of Diabetes in Mild to Moderately Obese Patients

NCT00965302
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Obesity
Interventions
Laparoscopic sleeve gastrectomy, Intensive medical management
Procedure · Behavioral
Lead sponsor
59th Medical Wing
Federal
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced Oct 1, 2026, 11:31 AM EDT
Completed Not applicable Interventional Results available

Diagnosing Intensive Care Unit (ICU) Acquired Weakness

NCT04166630
View directory record Official record
Conditions
ICU Acquired Weakness
Interventions
Clinical Electrical Stimulator
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 19, 2022 · Synced Oct 1, 2026, 11:31 AM EDT
Recruiting Not applicable Interventional

Rapid Evacuation and Access of Cerebral Hemorrhage Trial

NCT06870812
View directory record Official record
Conditions
Stroke Hemorrhagic
Interventions
Surgical management, Medical Management
Procedure · Other
Lead sponsor
Emory University
Other
Eligibility
18 Years to 70 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
24
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Palo Alto, California + 19 more
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 1, 2026, 11:31 AM EDT
Not listed No phase listed Observational

Evaluation of a Telehealth DPP With Medicare Patients at the University of Mississippi Medical Center

NCT04822480
View directory record Official record
Conditions
PreDiabetes, Prediabetic State
Interventions
Diabetes Prevention Program (DPP)
Behavioral
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Apr 29, 2024 · Synced Oct 1, 2026, 11:31 AM EDT
Completed Not applicable Interventional Results available

Improving Performance of Paracentesis in Medical Residency Training

NCT01403987
View directory record Official record
Conditions
Ascites, Cirrhosis
Interventions
Residency Program Teaching, Lecture, Pocket Card Reference, Pager
Behavioral · Other
Lead sponsor
Boston Medical Center
Other
Eligibility
Not listed
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 31, 2012 · Synced Oct 1, 2026, 11:31 AM EDT
Completed Not applicable Interventional

Testing MST to Improve Adherence Among Youth With Chronic Poor Metabolic Control

NCT00519935
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
Multisystemic Therapy
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
10 Years to 16 Years
Enrollment
127 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2006
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 2, 2017 · Synced Oct 1, 2026, 11:31 AM EDT
Completed Not applicable Interventional Results available

Addiction Housing Case Management for Homeless Veterans

NCT01346514
View directory record Official record
Conditions
Homelessness, Substance Abuse Disorders, Mental Disorders
Interventions
Intensive Addiction/Housing Case Management, Housing Support Group
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
181 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 28, 2017 · Synced Oct 1, 2026, 11:31 AM EDT
Not yet recruiting Not applicable Interventional

Evaluation of Community Health Worker Support to Help People With Serious Mental Illness to Quit Smoking

NCT07789132
View directory record Official record
Conditions
Nicotine Dependance, Serious Mental Illness, Smoking (Tobacco) Addiction, Tobacco Cessation, Community Health Workers, Cardiovascular (CV) Risk, Tobacco Use Disorder
Interventions
Integrated CHW Support intervention, Enhanced usual care (EUC)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
937 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 1, 2026, 11:31 AM EDT
Completed Not applicable Interventional Results available

Diabetes Data-Assisted Remission Trial (DDART)

NCT04663061
View directory record Official record
Conditions
Type 2 Diabetes, Obesity
Interventions
Medical weight loss, Diabetes education, Continuous glucose monitoring
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Oct 1, 2026, 11:31 AM EDT
Completed Not applicable Interventional Results available

Establishing Efficacy of a Functional-Restoration Based CAM Pain Management Program in Post-9/11 Veterans

NCT02657317
View directory record Official record
Conditions
Chronic Pain, Traumatic Brain Injury, Posttraumatic Stress Disorder, Depression, Opioid Use Disorder
Interventions
FORT-A, VA Treatment as Usual
Behavioral · Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 72 Years
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 29, 2024 · Synced Oct 1, 2026, 11:31 AM EDT
Not listed Not applicable Interventional

Less Invasive Detection and Treatment of Very Early Coronary Artery Disease in Patients With Diabetes Mellitus

NCT00797186
View directory record Official record
Conditions
Type 2 Diabetes, Microvascular Dysfunction
Interventions
Intensive risk factor management
Other
Lead sponsor
University of Virginia
Other
Eligibility
21 Years to 85 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated May 30, 2011 · Synced Oct 1, 2026, 11:31 AM EDT
Completed Not applicable Interventional Results available

COMRADE: Collaborative Care Management for Distress and Depression in Rural Diabetes

NCT02863523
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Diabetes-related Distress, Depression
Interventions
Integrated Behavioral Care
Behavioral
Lead sponsor
East Carolina University
Other
Eligibility
19 Years to 75 Years
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 8, 2023 · Synced Oct 1, 2026, 11:31 AM EDT
Completed Not applicable Interventional

The Attitudes, Communication, Treatment and Support Intervention to Reduce Breast Cancer Treatment Disparity

NCT01184066
View directory record Official record
Conditions
Breast Cancer
Interventions
ACTS Intervention, Usual Care
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 31, 2018 · Synced Oct 1, 2026, 11:31 AM EDT
Active, not recruiting No phase listed Observational

Symptomatic Carotid Outcomes Registry

NCT05300737
View directory record Official record
Conditions
Carotid Stenosis, Ischemic Stroke, Transient Ischemic Attack
Interventions
intensive medical therapy
Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
40 Years and older
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
11
States / cities
Hartford, Connecticut • Atlanta, Georgia • Chicago, Illinois + 7 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Oct 1, 2026, 11:31 AM EDT
Completed Not applicable Interventional Results available

Animal Assisted Interactions With Animal Robot in the Intensive Care Unit (ICU)

NCT05075395
View directory record Official record
Conditions
Acute Lymphoblastic Leukemia (ALL), Critical Illness, Physical Therapy Modalities, Occupational Therapy, Animal Assisted Therapy
Interventions
PARO therapy seal
Device
Lead sponsor
University of Nebraska
Other
Eligibility
5 Years to 18 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Dec 16, 2024 · Synced Oct 1, 2026, 11:31 AM EDT
Completed Not applicable Interventional Results available

Surgery or Lifestyle With Intensive Medical Management in the Treatment of Type 2 Diabetes

NCT01073020
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Obesity
Interventions
Allergan Adjustable Gastric Band Surgery, Intensive Medical Diabetes & Weight Management (Why WAIT) - Band Group, Roux-en-Y Gastric Bypass (RYGB) Surgery, Intensive Medical Diabetes & Weight Management (Why WAIT) - Bypass Group
Device · Other · Procedure
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
21 Years to 65 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 28, 2021 · Synced Oct 1, 2026, 11:31 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Invictus Medical, Medical Cranial Support Device (CSD) is a Device Safety Study in Infants at Risk of Head Ulcers.

NCT02224859
View directory record Official record
Conditions
Other Preterm Infants
Interventions
HCP will place the Invictus Cranial Support Device (CSD) on the patient, human intervention
Device · Other
Lead sponsor
Invictus Medical, Inc.
Industry
Eligibility
30 Weeks to 36 Weeks
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 24, 2015 · Synced Oct 1, 2026, 11:31 AM EDT