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Conditions: Diabetic Foot Ulcer (DFU), Venous Leg Ulcer (VLU), Pressure Ulcer (PU)
Interventions: dHPT, AIC; Biological
Lead sponsor: Cellution Biologics; Industry
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Environmental Exposures, Child Development, Lead and Injury Reduction
Interventions: Lead Hazard Control Intervention, Injury Hazard Control Intervention; Procedure
Lead sponsor: National Institute of Environmental Health Sciences (NIEHS); NIH
Eligibility: 18 Years and older · Female only
Enrollment: 468 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2018
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Advanced Solid Tumors Cancer, MSI-H Cancer
Interventions: NDI-219216; Drug
Lead sponsor: Nimbus Wadjet, Inc.; Industry
Eligibility: 18 Years to 99 Years
Enrollment: 134 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2031
U.S. locations: 11
States / cities: Los Angeles, California • Chicago, Illinois • Louisville, Kentucky + 8 more

Conditions: Rotator Cuff Tears, Rotator Cuff Injuries
Interventions: Tapestry Biointegrative Implant; Device
Lead sponsor: Zimmer Biomet; Industry
Eligibility: 21 Years and older
Enrollment: 170 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 3
States / cities: Pomona, California • Louisville, Kentucky • Baltimore, Maryland

Conditions: Peripheral Nerve Injury Upper Limb
Interventions: Avance Nerve Graft with Autologous BMAC; Procedure
Lead sponsor: Brooke Army Medical Center; Federal
Eligibility: 18 Years to 74 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 3
States / cities: Baltimore, Maryland • Bethesda, Maryland • Fort Sam Houston, Texas

Conditions: Abdominal Muscles/Ultrasonography, Adult, Ambulatory Surgical Procedures, Anesthetics, Local/Administration & Dosage, Ropivacaine/Administration & Dosage, Ropivacaine/Analogs & Derivatives, Hernia, Inguinal/Surgery, Humans, Nerve Block/Methods, Pain Measurement/Methods, Pain, Postoperative/Prevention & Control, Ultrasonography, Interventional
Interventions: TAP block; Procedure
Lead sponsor: Stamford Anesthesiology Services, PC; Other
Eligibility: 18 Years to 75 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2012
U.S. locations: 2
States / cities: Stamford, Connecticut

Conditions: Diabetic Foot Ulcers
Interventions: Total Contact Cast, Instant Total Contact Cast (ITCC), Removable Cast Walker (RCW); Device
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 225 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 4
States / cities: Tucson, Arizona • Dallas, Texas • Temple, Texas

Conditions: Non-Small Cell Lung Cancer
Interventions: Durvalumab, Danvatirsen, Ceralasertib, Vistusertib, Olaparib, Oleclumab, Trastuzumab deruxtecan, Cediranib; Drug
Lead sponsor: AstraZeneca; Industry
Eligibility: 18 Years to 99 Years
Enrollment: 528 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2026
U.S. locations: 17
States / cities: Duarte, California • Fullerton, California • La Jolla, California + 12 more

Conditions: Opioid Use
Interventions: Retrospective analysis of opioid use after surgery; Other
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 30,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2019
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Inguinal Hernia
Interventions: Not listed
Lead sponsor: Ascension Health; Industry
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2012
U.S. locations: 1
States / cities: Grand Blanc, Michigan

Conditions: Type 2 SLAP Lesions
Interventions: Biceps tenodesis, Labral repair; Procedure
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Endometrial Endometrioid Adenocarcinoma, Stage I Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8, Stage II Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8
Interventions: Biospecimen Collection, Brachytherapy, Computed Tomography, External Beam Radiation Therapy, Magnetic Resonance Imaging, Pembrolizumab, Quality-of-Life Assessment, Questionnaire Administration, X-Ray Imaging; Procedure · Radiation · Biological + 1 more
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: 18 Years and older · Female only
Enrollment: 164 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2027
U.S. locations: 275
States / cities: Birmingham, Alabama • Clovis, California • Concord, California + 195 more

Conditions: Wound Heal
Interventions: innovaMatrix AC; Device
Lead sponsor: ConvaTec Inc.; Industry
Eligibility: 18 Years to 100 Years
Enrollment: 67 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Mt. Pleasant, South Carolina

Conditions: Rotator Cuff Tears
Interventions: Liposomal bupivacaine, Bupivacaine Hcl 0.25% Inj; Drug
Lead sponsor: Carilion Clinic; Other
Eligibility: 18 Years and older
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Roanoke, Virginia

Conditions: Wound Healing and Scar Quality Following Mohs Surgery and Excisional Dermatologic Surgery
Interventions: Porcine xenograft; Device
Lead sponsor: Northwell Health; Other
Eligibility: 18 Years and older
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 2
States / cities: Bay Shore, New York • Lake Success, New York

Conditions: Hip Fractures, Anesthesia, Delirium
Interventions: cerebral oximeter (Fore-Sight), depth of anesthesia monitor (BIS), BP management, General anesthesia, propofol, fentanyl, sevoflurane; Device · Procedure · Drug
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 65 Years and older
Enrollment: 145 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Abdominal Aortic Aneurysm (AAA)
Interventions: Aortoiliac Occlusive Disease Group - PET-CT imaging with injection of 64Cu-DOTA-ECL1i, AAA Group- PET-CT imaging with injection of 64Cu-DOTA-ECL1i; Diagnostic Test
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 45 Years to 75 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Prostate Cancer, Adenocarcinoma of the Prostate
Interventions: Olaparib Pill, Prostatectomy; Drug · Procedure
Lead sponsor: Brown University; Other
Eligibility: 18 Years and older · Male only
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Loss of Teeth Due to Extraction
Interventions: Cytoplast® TXT-200, MinerOss® Cortical and Cancellous Chips (FDBA), Open Flap Technique, Closed Flap Technique; Device · Procedure
Lead sponsor: Tufts University; Other
Eligibility: 18 Years and older
Enrollment: 13 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Subacute Stroke, Acute Stroke
Interventions: MindPod Dolphin VGT, Bimanual Arm Trainer VGT; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 21 Years to 90 Years
Enrollment: 58 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Diabetic Foot Ulcer
Interventions: Exercise; Behavioral
Lead sponsor: Mercer University; Other
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Jaw Fractures, Jaw; Fracture, Upper Jaw, Mandibular Fractures, Maxilla Fracture, Jaw Fixation
Interventions: dental occlusion ties maxillo-mandibular fixation; Device
Lead sponsor: Altru Health System; Other
Eligibility: 12 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Grand Forks, North Dakota

Conditions: Ovarian Cancer
Interventions: Paclitaxel, Cisplatin, Bioferon, Rintatolimod, αDC1 Vaccine, Pembrolizumab, Celecoxib, Debulking Procedure; Drug · Biological · Procedure
Lead sponsor: Kalinski, Pawel, MD, PhD; Other
Eligibility: 18 Years and older · Female only
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Mitral Valve Regurgitation
Interventions: Mitral valve repair, Transcatheter edge-to-edge repair; Procedure · Device
Lead sponsor: Annetine Gelijns; Other
Eligibility: 60 Years and older
Enrollment: 450 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2030
U.S. locations: 24
States / cities: Los Angeles, California • San Francisco, California • Stanford, California + 16 more

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Evaluation of the Safety and Efficacy of Dehydrated Human Placenta Tissue (dHPT) for Wound Healing

HOME Study (Health Outcomes and Measures of the Environment Study)

A Study to Assess the Safety, Tolerability, and Efficacy of NDI-219216 in Patients With Advanced Solid Tumors.

Tapestry Rotator Cuff Repair PMCF

BMAC Nerve Allograft Study

Medial Versus Traditional Approach to US-guided TAP Blocks for Open Inguinal Hernia Repair

Instant Total Contact Cast to Heal Diabetic Foot Ulcers

Phase II Umbrella Study of Novel Anti-cancer Agents in Participants With NSCLC Who Progressed on an Anti-PD-1/PD-L1 Containing Therapy

A Difference-In-Differences Analysis of New Persistent Opioid Use After Surgery

Comparison of Patient Perceived Pain and Satisfaction Between Lightweight and Heavyweight Mesh for Laparoscopic Inguinal Hernia Repair

Outcomes of Biceps Tenodesis or Labral Repair for Treatment of Type 2 Superior Labrum Anterior and Posterior Lesions

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to the Usual Radiation Treatment for Newly Diagnosed Early Stage High Intermediate Risk Endometrial Cancer

A Retrospective, Observational Study of the Real-world Safety and Performance of InnovaMatrix® AC at a Single Centre

Measuring Opioid Use After Rotator Cuff Repair: Comparing the Effects of Standard vs. Extended-release Nerve Blocks

Porcine Xenograft Versus Second Intention Healing

Does Optimized General Anesthesia Care Reduce Postoperative Delirium?

CCR2 AAA Pilot Study

BrUOG 337: Olaparib Prior to Radical Prostatectomy For Advanced Prostate Cancer Defects in DNA Repair Genes

A Comparison Between Primary and Secondary Flap Coverage in Extraction Sites: A Pilot Study

Feasibility of Video Gaming Technology for Arm Recovery Early Post-stroke

The Effect of Exercise on Wound Healing While Off-loading

Minimally Invasive Dental Occlusion Ties

Intensive Locoregional Chemoimmunotherapy, Intradermal Autologous Alpha-DC1 Vaccines, and Systemic Pembrolizumab for Advanced-Stage Ovarian Cancer

Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY)