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ClinicalTrials.gov public records Last synced Nov 6, 2026, 5:49 PM EST

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Showing 1–20 of 20 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Intranasal mupirocin Clear all

Conditions: Healthcare Associated Infections, Methicillin Resistant Staphylococcus Aureus, Multi Drug Resistant Organisms
Interventions: Arm 2: Decolonization; Drug
Lead sponsor: University of California, Irvine; Other
Eligibility: 12 Years and older
Enrollment: 53 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 52
States / cities: West Hills, California • Thornton, Colorado • Bradenton, Florida + 42 more

Conditions: Sarcoma,Soft Tissue
Interventions: 2% intranasal mupirocin ointment, 4% chlorhexidine gluconate body cleanser; Drug
Lead sponsor: Adam Olson; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Staphylococcus Aureus, HIV Infections
Interventions: Mupirocin calcium ointment, 2%, Placebo ointment; Drug
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2006
U.S. locations: 2
States / cities: New York, New York • The Bronx, New York

Conditions: MRSA Colonization
Interventions: Chlorhexidine, Mupirocin, Soap baths, Lubricating Jelly; Drug
Lead sponsor: University of Tennessee; Other
Eligibility: 18 Years and older
Enrollment: 55 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Chattanooga, Tennessee

Conditions: Endophthalmitis, Cataract Surgery, Prophylaxis
Interventions: mupirocin ointment, SOC sterilization; Drug · Other
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years and older
Enrollment: 37 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2006
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Staphylococcus Aureus
Interventions: CA-MRSA Decolonization; Other
Lead sponsor: Ann & Robert H Lurie Children's Hospital of Chicago; Other
Eligibility: Female only
Enrollment: 107 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2013
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Atopic Dermatitis
Interventions: Sodium hypochlorite (bleach) baths, Mupirocin ointment, Water, Petrolatum Ointment; Drug
Lead sponsor: Northwestern University; Other
Eligibility: 6 Months to 17 Years
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2011
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Staphylococcal Aureus Infection, Microbial Colonization, Pediatric Infection, S. Aureus Colonization, Microbial Transplant
Interventions: Nasal Microbiota Transplant (NMT), Placebo; Biological
Lead sponsor: Johns Hopkins University; Other
Eligibility: 0 Years to 60 Years
Enrollment: 175 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Surgical Site Infection
Interventions: Mupirocin, Chlorhexidine gluconate, Cefazolin, Vancomycin, Nasal Povidone Iodine; Drug
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 23,005 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2021
U.S. locations: 11
States / cities: Miami, Florida • Iowa City, Iowa • Baltimore, Maryland + 8 more

Conditions: Human Microbiome
Interventions: Intranasal Mupirocin and Topical Chlorhexidine; Drug
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 50 Years and older
Enrollment: 19 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2015
U.S. locations: 2
States / cities: Baltimore, Maryland • Perry Point, Maryland

Conditions: Staphylococcus Aureus
Interventions: Arm 1. Routine Care (Mupirocin/CHG), Arm 2. Iodophor/CHG Decolonization; Drug
Lead sponsor: Harvard Pilgrim Health Care; Other
Eligibility: Not listed
Enrollment: 353,323 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 137
States / cities: Riverside, California • San Jose, California • Thousand Oaks, California + 103 more

Conditions: Methicillin-resistant Staphylococcus Aureus
Interventions: Chlorhexidine bath and nasal mupirocin; Drug
Lead sponsor: Harvard Pilgrim Health Care; Other
Eligibility: 13 Years and older
Enrollment: 74,256 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 42
States / cities: Anchorage, Alaska • Thousand Oaks, California • Aurora, Colorado + 32 more

Conditions: Breast Cancer, Breast Cancer Female
Interventions: Mometasone Furoate 1% Cream, Mepitel Film, Intranasal mupirocin, Chlorhexidine body cleansing; Drug · Device · Dietary Supplement + 1 more
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 138 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 7
States / cities: Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more

Conditions: Bacterial Colonization
Interventions: Mupirocin, Chlorhexidine baths; Drug
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Human Microbiome
Interventions: Mupirocin calcium ointment, 2%, Topical Chlorhexidine, 4%; Drug
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 58 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Radiation Dermatitis
Interventions: Bacterial decolonization, Mometasone furoate 0.1% cream, Bacterial decolonization and Mometasone furoate 0.1% cream; Drug
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Cystic Fibrosis
Interventions: Inhaled Vancomycin, Placebo (Sterile Water), Rifampin, Trimethoprim/Sulfamethoxazole (TMP/SMX), Doxycycline, Mupirocin Intranasal Creme, 4% chlorhexidine gluconate liquid skin cleanser; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 12 Years and older
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 2
States / cities: Baltimore, Maryland • Cleveland, Ohio

Conditions: Staph Aureus Colonization, Staph Aureus Infection
Interventions: Mupirocin and Chlorhexidine, Placebo ointment and placebo cloths; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: Not listed
Enrollment: 307 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2019
U.S. locations: 2
States / cities: Baltimore, Maryland

Conditions: Radiation Dermatitis
Interventions: Chlorhexidine gluconate solution, Mupirocin Ointment; Drug
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Staphylococcal Infection
Interventions: Mupirocin calcium; Drug
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: Up to 24 Months
Enrollment: 155 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 6
States / cities: Atlanta, Georgia • Baltimore, Maryland • Kansas City, Missouri + 3 more

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Active Bathing to Eliminate Infection (ABATE Infection) Trial

Bacterial Decolonization Plus Intraoperative Angiography for Soft Tissue Sarcomas Receiving Preoperative Radiotherapy (CONCERTO)

Mupirocin Ointment to Eliminate Nasal Carriage of Staphylococcus Aureus in HIV Infection

MRSA in a Trauma Population: Does Decolonization Prevent Infection?

Prophylaxis Prior to Cataract Surgery Conjunctival Flora and Optimal Ocular Sterilization Technique Prior to Cataract Surgery

A Prospective Cohort Pilot Study of the Clinical and Molecular Epidemiology of Staphylococcus Aureus in Pregnant Women at the Time of Group B Streptococcal Screening in a Large Urban Medical Center in Chicago, IL USA

The Impact of Treating Staphylococcus Aureus Infection and Colonization on the Clinical Severity of Atopic Dermatitis

Administering NMT to Reestablish Infant Nasal Microbiome Diversity Following Intranasal Mupirocin Treatment

Checklist to Prevent MRSA Surgical Site Infections

Human Microbiome and Healthcare Associated Infections - Nursing Home Dwelling Older Veterans

Mupirocin-Iodophor ICU Decolonization Swap Out Trial

Cluster Randomized Trial of Hospitals to Assess Impact of Targeted Versus Universal Strategies to Reduce Methicillin-resistant Staphylococcus Aureus (MRSA) in Intensive Care Units (ICUs)

A Study of Different Skin Care Approaches to Prevent Skin Reactions in People With Breast Cancer Receiving Radiation Therapy After Mastectomy

Bacterial Decolonization Within Dyads

Cultures Before and After Decolonization in Community Dwelling Adults With Current S. Aureus Colonization

Topical Steroids & Bacterial Decolonization for Radiation Dermatitis

Persistent Methicillin Resistant Staphylococcus Aureus Eradication Protocol (PMEP)

Treating Parents to Reduce NICU Transmission of Staphylococcus Aureus Trial

Bacterial Decolonization to Prevent Radiation Dermatitis

Safety and Efficacy of Mupirocin in Eradicating Colonization With S. Aureus in Critically Ill Infants