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Showing 1–22 of 22 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Intraosseous access Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Proximal Humerus Site for Anesthesia

NCT01866514
View directory record Official record
Conditions
Intraosseous Vascular Access
Interventions
intraosseous vascular access in the proximal humerus, EZ-IO
Device
Lead sponsor
Vidacare Corporation
Industry
Eligibility
21 Years and older
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Spring Branch, Texas
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Sep 3, 2026, 6:40 AM EDT
Completed No phase listed Observational

Ultrasonographic Identification of the Proximal Humerus Landmarks

NCT03121794
View directory record Official record
Conditions
Proximal Humerus Interosseous Venous Access, Anatomic Landmark, Ultrasonography
Interventions
Ultrasonographic exam, ultrasound machine
Procedure · Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 17, 2020 · Synced Sep 3, 2026, 6:40 AM EDT
Completed Phase 2 Interventional Results available

Safety & Tolerability of Hypertonic Saline Administration Via Intraosseous Access

NCT03276494
View directory record Official record
Conditions
Stroke, Intracranial Hypotension, Cerebral Edema
Interventions
Intraosseous, Hypertonic saline
Device · Drug
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 8, 2019 · Synced Sep 3, 2026, 6:40 AM EDT
Recruiting Phase 2 Interventional

CAlcium and VAsopressin Following Injury Early Resuscitation (CAVALIER) Trial

NCT05958342
View directory record Official record
Conditions
Trauma, Hemorrhage
Interventions
Calcium Gluconate, Vasopressin, saline placebo
Drug
Lead sponsor
Jason Sperry
Other
Eligibility
18 Years to 90 Years
Enrollment
1,050 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
16
States / cities
Chandler, Arizona • Tucson, Arizona • Little Rock, Arkansas + 11 more
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Sep 3, 2026, 6:40 AM EDT
Completed Not applicable Interventional Results available

INTRACEPT: Prospective, Randomized, Multi-center Study Intraosseous Basivertebral Nerve Ablation for Treatment of CLBP

NCT03246061
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Intracept System, Standard Care
Device · Other
Lead sponsor
Relievant Medsystems, Inc.
Industry
Eligibility
25 Years to 70 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
18
States / cities
Birmingham, Alabama • Phoenix, Arizona • Los Angeles, California + 15 more
Source: ClinicalTrials.gov public record
Updated Apr 1, 2024 · Synced Sep 3, 2026, 6:40 AM EDT
Completed Not applicable Interventional

Single-operator Ultrasound-guided IV Placement by Emergency Nurses

NCT01439113
View directory record Official record
Conditions
Intravenous Infusions
Interventions
Ultrasound guided IV placement
Procedure
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
2
States / cities
Boston, Massachusetts • Springfield, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 27, 2023 · Synced Sep 3, 2026, 6:40 AM EDT
Completed No phase listed Observational

Observation of Intraosseous Vascular Access in the Emergency Department

NCT01235078
View directory record Official record
Conditions
Patients Requiring Urgent Vascular Access
Interventions
EZ-IO
Device
Lead sponsor
Vidacare Corporation
Industry
Eligibility
Not listed
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
6
States / cities
Gulf Breeze, Florida • Pensacola, Florida • Park Ridge, Illinois + 3 more
Source: ClinicalTrials.gov public record
Updated Dec 14, 2025 · Synced Sep 3, 2026, 6:40 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Infusion Flow Rates and Blood Sampling

NCT02021617
View directory record Official record
Conditions
Intraosseous Access, Infusion Rates, Intraosseous Blood, Venous Blood
Interventions
Intraosseous access
Device
Lead sponsor
Vidacare Corporation
Industry
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Spring Branch, Texas
Source: ClinicalTrials.gov public record
Updated Dec 26, 2013 · Synced Sep 3, 2026, 6:40 AM EDT
Withdrawn Not applicable Interventional

EZIO Compared to Central Venous Lines for Emergency Vascular Access

NCT00785252
View directory record Official record
Conditions
Catheters, Indwelling, Central Venous Line, Intraosseous Needle
Interventions
Powered Intraosseous device (EZIO), standard central line
Device
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 27, 2021 · Synced Sep 3, 2026, 6:40 AM EDT
Withdrawn No phase listed Observational

Rapid Sequence Intubation Drug Delivery Using Intraosseous and IV Access in Pediatric Patients Observational Study

NCT01634867
View directory record Official record
Conditions
Airway Control
Interventions
Not listed
Lead sponsor
Vidacare Corporation
Industry
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Sep 3, 2026, 6:40 AM EDT
Completed Not applicable Interventional Results available

SMART Clinical Study: Surgical Multi-center Assessment of RF Ablation for the Treatment of Vertebrogenic Back Pain

NCT01446419
View directory record Official record
Conditions
Low Back Pain
Interventions
Intracept Treatment, Sham Treatment
Device
Lead sponsor
Relievant Medsystems, Inc.
Industry
Eligibility
25 Years to 70 Years
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
13
States / cities
Phoenix, Arizona • Daly City, California • Long Beach, California + 10 more
Source: ClinicalTrials.gov public record
Updated Oct 30, 2016 · Synced Sep 3, 2026, 6:40 AM EDT
Completed Not applicable Interventional Results available

Intraosseous Versus Intravenous Vascular Access During Cardiac Arrest

NCT01119807
View directory record Official record
Conditions
Cardiac Arrest
Interventions
Intravenous access during OHCA, Humeral IO insertion, TIbial IO insertion
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 110 Years
Enrollment
182 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 2, 2022 · Synced Sep 3, 2026, 6:40 AM EDT
Completed Not applicable Interventional

Intraosseous Catheter Confirmation Study

NCT03908879
View directory record Official record
Conditions
Critical Illness
Interventions
Standard intraosseous (IO) catheter confirmation procedure, Color flow Doppler intraosseous (IO) catheter confirmation procedure, Pressure transduction intraosseous (IO) catheter confirmation procedure
Procedure
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 7, 2023 · Synced Sep 3, 2026, 6:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Continuous Intraosseous Vascular Access Over 48 Hours

NCT01866475
View directory record Official record
Conditions
Intraosseous Vascular Access
Interventions
EZ-IO
Device
Lead sponsor
Vidacare Corporation
Industry
Eligibility
21 Years and older
Enrollment
127 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Apr 8, 2024 · Synced Sep 3, 2026, 6:40 AM EDT
Terminated No phase listed Observational Results available

Observational Study of CT Dye Administration Through the Intraosseous Vascular Access Route

NCT01531686
View directory record Official record
Conditions
Patients With Intraosseous Vascular Access Requiring Computed Tomography (CT) Exam
Interventions
Intraosseous delivery of CT contrast dye
Procedure
Lead sponsor
Vidacare Corporation
Industry
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
4
States / cities
Phoenix, Arizona • Sylmar, California • Gainesville, Florida + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Sep 3, 2026, 6:40 AM EDT
Completed Not applicable Interventional Results available

Intraosseous Access in the Emergency Department for Patients With Failed Attempts at Intravenous Access: A Randomized Trial Examining Resource Utilization and Patient Satisfaction

NCT01676350
View directory record Official record
Conditions
Difficult Peripheral IV Access
Interventions
IO access using EZ-IO®
Procedure
Lead sponsor
WellSpan Health
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • York, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 22, 2022 · Synced Sep 3, 2026, 6:40 AM EDT
Completed Phase 3 Interventional

Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis

NCT04102371
View directory record Official record
Conditions
Shock, Septic
Interventions
Lactated Ringer, Normal Saline, Plasma-lyte
Drug
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
2 Months to 17 Years
Enrollment
9,041 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
22
States / cities
Davis, California • Los Angeles, California • San Francisco, California + 19 more
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Sep 3, 2026, 6:40 AM EDT
Terminated No phase listed Observational Results available

Observational Study of Rapid Sequence Intubation Drug Delivery Using Intraosseous and Intravenous Access.

NCT01486407
View directory record Official record
Conditions
Airway Control
Interventions
Not listed
Lead sponsor
Vidacare Corporation
Industry
Eligibility
Not listed
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
2
States / cities
Corpus Christi, Texas • El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Sep 3, 2026, 6:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Follow-Up Study Validating a Blended Technique to Identify the Proximal Humerus Intraosseous Vascular Access Site

NCT01866501
View directory record Official record
Conditions
Intraosseous Vascular Access, Vascular Access
Interventions
Intraosseous Vascular Access
Device
Lead sponsor
Vidacare Corporation
Industry
Eligibility
21 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Spring Branch, Texas
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Sep 3, 2026, 6:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Various Methods Used to Identify the Proximal Humerus Intraosseous Vascular Access Site

NCT01742780
View directory record Official record
Conditions
Vascular Access
Interventions
Intraosseous Vascular Access
Other
Lead sponsor
Vidacare Corporation
Industry
Eligibility
21 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Spring Branch, Texas
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Sep 3, 2026, 6:40 AM EDT
Completed Phase 1 Interventional Results available

Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis: A Pilot Feasibility Study

NCT03340805
View directory record Official record
Conditions
Shock, Septic
Interventions
Lactated Ringer, Normal saline
Drug
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
6 Months to 17 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 4, 2019 · Synced Sep 3, 2026, 6:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Healthy Adult Volunteer Study of Intraosseous Infusion Using the Sternum

NCT01853215
View directory record Official record
Conditions
Intraosseous Vascular Access
Interventions
T.A.L.O.N. Intraosseous System
Device
Lead sponsor
Vidacare Corporation
Industry
Eligibility
21 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Spring Branch, Texas
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Sep 3, 2026, 6:40 AM EDT