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Showing 73–96 of 116 matching trials from the live ClinicalTrials.gov search.
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Comparative Analysis of Spinal Anesthesia Versus General Anesthesia for vNOTES

NCT05688943
Conditions
Anesthesia, Tubal Ligation
Interventions
Spinal Anesthesia, General Anesthesia
Procedure
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
21 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Kansas City, Kansas
Conditions
Pain
Interventions
Lidocaine, Placebo
Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
5 Years to 19 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
New York, New York
Completed Phase 2 Interventional Results available

The Effect of Opioid-Free Anesthesia in TMJ Surgery

NCT04724759
Conditions
Temporomandibular Joint Disorders
Interventions
Dexmedetomidine / Ketamine / Lidocaine
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Results available

The Effect of Intravenous Lidocaine on Allodynia

NCT00659633
Conditions
Pain
Interventions
lidocaine
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Birmingham, Alabama
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Vibrating, Cold Device for Pediatric Intravenous (IV) Cannulation Pain Relief

NCT01394250
Conditions
Pain, Anxiety
Interventions
Buzzy, Topical Lidocaine 4% Cream
Device · Drug
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
4 Years to 18 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Terminated Phase 4 Interventional Results available

IV Lidocaine in Pediatric AIS

NCT03893318
Conditions
Systemic Lidocaine Improves Pain Control After Surgery by Attenuating the Systemic Inflammatory Response to Surgery
Interventions
IV lidocaine, Placebos
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
12 Years to 18 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
St Louis, Missouri
Terminated Phase 4 Interventional Results available

Postoperative Pain Control Following Renal Transplant

NCT05044429
Conditions
Kidney Transplant; Complications, Pain, Postoperative
Interventions
Intravenous Lidocaine, Transversus abdominis plane (TAP) block, Quadratus Lumborum (QL) Block
Drug
Lead sponsor
George Washington University
Other
Eligibility
18 Years to 99 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Improving Pain Control in Paraesophageal Hernia Repair: Intravenous Lidocaine Versus Placebo

NCT04096170
Conditions
Hernia, Paraesophageal
Interventions
IV lidocaine, Placebo
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
Charlotte, North Carolina
Conditions
Chronic Pain
Interventions
Lidocaine infusion, Saline infusion
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
2
States / cities
Dallas, Texas
Completed Phase 2 Interventional Results available

Lidocaine Patches Prior to Intravenous Insertion

NCT00552695
Conditions
Need for Intravenous Catheter
Interventions
Lidocaine tetracaine, Placebo
Device
Lead sponsor
Stony Brook University
Other
Eligibility
3 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Stony Brook, New York
Conditions
Dysphagia, GERD, Abdominal Pain
Interventions
Lidocaine, Placebo
Drug
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 89 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Conditions
Pain
Interventions
J-tip jet injection of 1% buffered lidocaine
Procedure
Lead sponsor
Norton Healthcare
Other
Eligibility
8 Years to 15 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
1
States / cities
Louisville, Kentucky
Conditions
Rib Fractures, Rib Trauma, Rib Fracture Multiple, Pain, Acute
Interventions
lidocaine, ketamine intravenous infusion, paravertebral block with ropivicaine
Combination Product · Drug
Lead sponsor
George Washington University
Other
Eligibility
18 Years to 80 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Conditions
Rhinosinusitis Chronic, Sinus Cancer, Sinus Polyp, Encephalocele
Interventions
Tranexamic acid injection, Total Intravenous Anesthesia, Inhalational isoflurane
Drug
Lead sponsor
Our Lady of the Lake Hospital
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Completed Not applicable Interventional Accepts healthy volunteers

Lung-Resident Memory Th2 Cells in Asthma

NCT03455959
Conditions
Asthma, Allergic
Interventions
Bronchoscopy/BAL, Airway Brushing
Procedure
Lead sponsor
Andrew D. Luster, M.D.,Ph.D.
Other
Eligibility
18 Years to 55 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Analgesic Drug Dependence, Colectomy
Interventions
Opioid Anesthesia, Opioid-free Anesthesia
Drug
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Tampa, Florida
Conditions
Hypercapnia
Interventions
standard of care for phase one anesthesia care, Quick Emergence Device
Other · Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Salt Lake City, Utah
Completed No phase listed Observational Accepts healthy volunteers

Pharmacologic MRI in Cocaine Addiction

NCT01652378
Conditions
Cocaine Dependence
Interventions
ondansetron, lidocaine
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
21 Years to 64 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Stroke
Interventions
Sedation, General Anesthesia (GA), Intra-arterial Thrombectomy
Drug · Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 90 Years
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
11
States / cities
Indianapolis, Indiana • Iowa City, Iowa • Louisville, Kentucky + 6 more
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Outcomes of Neuraxial Anesthetic Technique on the Trial of Labor After Cesarean (TOLAC)

NCT02105558
Conditions
Labor Pain, Complications; Cesarean Section, Pregnancy
Interventions
Epidural anesthesia, Combined spinal and epidural anesthesia
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Houston, Texas
Conditions
Neoplasms, Pain
Interventions
Lidocaine
Drug
Lead sponsor
San Diego Hospice & Palliative Care
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
San Diego, California
Conditions
Rhytidoplasty
Interventions
clonidine, glycopyrrolate, propofol, ketamine, marcaine, scopolamine, midazolam, ondansetron, metoclopramide, lidocaine, famotidine, desflurane, sevoflurane
Drug · Device
Lead sponsor
Mercy Facial Plastic Surgery Center
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Springfield, Missouri
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

A Pilot Study of Local Anesthesia for Inguinal Hernia Surgery in Older Adults

NCT04706026
Conditions
Inguinal Hernia, Anesthesia, Local
Interventions
Open Inguinal Hernia Repair - Local Anesthesia, Inguinal Hernia Repair - General Anesthesia
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
60 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
3
States / cities
Dallas, Texas • Houston, Texas • Madison, Wisconsin
Conditions
Headache, Tumor, Seizure Disorder, Neurofibromatoses, Hydrocephalus, Abdominal Neoplasm, Spine Deformity
Interventions
propofol, Dexmedetomidine, Glycopyrrolate, Lidocaine 1% Injectable Solution, Nitrous Oxide, Sevoflurane
Drug
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
12 Months to 60 Months
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Milwaukee, Wisconsin