SEdation Versus General Anesthesia for Endovascular Therapy in Acute Ischemic Stroke
Public ClinicalTrials.gov record NCT03263117. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
SEGA - SEdation Versus General Anesthesia for Endovascular Therapy in Acute Ischemic Stroke - a Randomized Comparative Effectiveness Trial.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Objectives: This study aims to estimate overall treatment benefit (improvement in disability) among acute ischemic stroke patients that are randomized to General Anesthesia (GA) compared with Sedation (CS) during endovascular therapy. Assess safety (as measured by incidence of symptomatic intracranial hemorrhage); rates of Endovascular therapy (EVT) procedural complications, reperfusion; and quality of life. Hypothesis: GA during EVT for acute ischemic stroke improves functional outcomes at 90 days compared to sedation.
Study identification
- NCT ID
- NCT03263117
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 260 participants
Conditions and interventions
Conditions
Interventions
- Sedation Drug
- General Anesthesia (GA) Drug
- Intra-arterial Thrombectomy Procedure
Drug · Procedure
Eligibility (public fields only)
- Age range
- 18 Years to 90 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 1, 2018 (Actual)
- Primary completion
- Apr 22, 2023 (Actual)
- Completion
- Apr 22, 2023 (Actual)
- Last update posted
- Nov 26, 2025
2018 – 2023
United States locations
- U.S. sites
- 11
- U.S. states
- 7
- U.S. cities
- 9
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Indiana University College of Medicine | Indianapolis | Indiana | 46202 | — |
| University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242 | — |
| Henry Ford Health System | Louisville | Kentucky | 48150 | — |
| Rochester Regional Health | Rochester | New York | 14617 | — |
| Wake Forest Baptist Health | Winston-Salem | North Carolina | 27157 | — |
| Geisinger Health | Danville | Pennsylvania | 17822 | — |
| Temple University | Philadelphia | Pennsylvania | 19122 | — |
| Memorial Hermann Hospital System - Memorial City Medical Center | Houston | Texas | 77024 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| University of Texas Health Science Center Houston with Memorial Hermann Hospital System - The Medical Center | Houston | Texas | 77030 | — |
| Memorial Hermann Hospital System - The Woodlands Medical Center | The Woodlands | Texas | 77380 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03263117, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 26, 2025 · Synced Oct 17, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03263117 live on ClinicalTrials.gov.