- Conditions
- Anterior Cruciate Ligament Reconstruction
- Interventions
- iovera°
- Device
- Lead sponsor
- Pacira Pharmaceuticals, Inc
- Industry
- Eligibility
- 18 Years to 49 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- New York, New York
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Showing 1–20
of 20
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- ACL Tear, Post Operative Pain
- Interventions
- Iovera, Celecoxib, Acetaminophen, Oxycodone, Tramadol, Bupivacaine Hydrochloride, Acetaminophen 500Mg Cap
- Device · Drug
- Lead sponsor
- Matthew Varacallo
- Other
- Eligibility
- 15 Years and older
- Enrollment
- 32 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- DuBois, Pennsylvania
- Conditions
- Chronic Low-back Pain
- Interventions
- iovera system, Radiofrequency ablation alone
- Device
- Lead sponsor
- University of Kansas Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Kansas City, Kansas
- Conditions
- Knee Osteoarthritis
- Interventions
- iovera°, Sham Comparator
- Device
- Lead sponsor
- Pacira Pharmaceuticals, Inc
- Industry
- Eligibility
- 35 Years to 75 Years
- Enrollment
- 180 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2016
- U.S. locations
- 17
- States / cities
- Covina, California • Sacramento, California • Bradenton, Florida + 14 more
- Conditions
- Postoperative Pain
- Interventions
- Cryoanalgesia, Sham Cryoanalgesia
- Device
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Post-Operative Pain Management
- Interventions
- ioveraº, ioveraº sham
- Device
- Lead sponsor
- Pacira Pharmaceuticals, Inc
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 79 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 7
- States / cities
- Fremont, California • Pasadena, California • Tamarac, Florida + 4 more
- Conditions
- Ankle Osteoarthritis
- Interventions
- iovera
- Device
- Lead sponsor
- University of Kansas Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2021
- U.S. locations
- 1
- States / cities
- Kansas City, Kansas
- Conditions
- Rib Fractures
- Interventions
- Cryoneurolysis of Intercostal Nerves, Standard of Care
- Device · Other
- Lead sponsor
- Stanford University
- Other
- Eligibility
- 18 Years to 64 Years
- Enrollment
- 43 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- Palo Alto, California
- Conditions
- Osteo Arthritis Knee
- Interventions
- Cryoneurolysis (Iovera)
- Procedure
- Lead sponsor
- Fondren Orthopedic Group L.L.P.
- Other
- Eligibility
- 18 Years to 90 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Mastectomy, Upper Limb Amputation Below Elbow, Upper Limb Amputation Above Elbow, Lower Limb Amputation Below Knee, Lower Limb Amputation Above Knee, Knee Arthropathy, Shoulder Arthroplasty, Rotator Cuff Repair, Video-Assisted Thoracoscopic Surgery (VATS), Skin Grafting
- Interventions
- Cryoneurolysis (active), Sham cryoneurolysis procedure
- Device
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 99 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- San Diego, California
- Conditions
- Spasticity, Cerebral or Spinal Condition
- Interventions
- iovera° system, sham iovera° system treatment
- Device
- Lead sponsor
- Pacira Pharmaceuticals, Inc
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 132 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 18
- States / cities
- Downey, California • Santa Monica, California • Bradenton, Florida + 15 more
- Conditions
- Arthritis of the Knee
- Interventions
- iovera°, iovera° Sham
- Device
- Lead sponsor
- Pacira Pharmaceuticals, Inc
- Industry
- Eligibility
- 22 Years to 79 Years
- Enrollment
- 150 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2016
- U.S. locations
- 8
- States / cities
- San Diego, California • Englewood, Colorado • Fort Lauderdale, Florida + 5 more
- Conditions
- Low Back Pain, Facet Joint Pain
- Interventions
- iovera system, Radiofrequency ablation
- Device
- Lead sponsor
- Medical Pain Management Services, PLLC
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Saratoga Springs, New York
- Conditions
- Intermetatarsal Neuroma
- Interventions
- Cryoablation, Lidocaine, Saline
- Device · Drug
- Lead sponsor
- Icahn School of Medicine at Mount Sinai
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- ACL Reconstruction (ACLR) With a Bone-patellar Tendon-bone (BPTB) Autograft
- Interventions
- Pacira Iovera Cryoneurolysis device, Placebo/Sham device
- Device
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Morton's Neuroma, Pain Management
- Interventions
- Cryoanalgesia (iovera°®)
- Device
- Lead sponsor
- Northern California Research Trials, Inc.
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 5 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 2
- States / cities
- Fairfield, California • Vacaville, California
- Conditions
- Wrinkles
- Interventions
- Cryotherapy for the utilization of wrinkle reduction (iovera)
- Device
- Lead sponsor
- Pacira Pharmaceuticals, Inc
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 47 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013 – 2014
- U.S. locations
- 1
- States / cities
- Redwood City, California
- Conditions
- Forehead Wrinkles
- Interventions
- iovera
- Device
- Lead sponsor
- Pacira Pharmaceuticals, Inc
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 85 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013 – 2014
- U.S. locations
- 6
- States / cities
- Roseville, California • Chicago, Illinois • Chestnut Hill, Massachusetts + 3 more
- Conditions
- Total Knee Arthroplasty
- Interventions
- iovera°
- Device
- Lead sponsor
- Pacira Pharmaceuticals, Inc
- Industry
- Eligibility
- 22 Years to 79 Years
- Enrollment
- 124 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2019
- U.S. locations
- 1
- States / cities
- Germantown, Tennessee
- Conditions
- Low Back Pain, Chronic
- Interventions
- Iovera Medial Branch Cryoneurolysis, Radiofrequency ablation (RFA)
- Device · Procedure
- Lead sponsor
- Montefiore Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 110 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- The Bronx, New York