Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 13, 2026, 5:21 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 937–960 of 1,141 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Isotonic solution Clear all

Conditions: Wound Infection
Interventions: Normal saline, Prontosan; Drug · Device
Lead sponsor: Georgetown University; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Cystic Fibrosis
Interventions: Active Treatment Group 7% Hypertonic Saline, Control Group 0.9% Isotonic Saline; Drug
Lead sponsor: University of Washington, the Collaborative Health Studies Coordinating Center; Other
Eligibility: 3 Years to 5 Years
Enrollment: 116 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2021
U.S. locations: 7
States / cities: Aurora, Colorado • Indianapolis, Indiana • St Louis, Missouri + 4 more

Conditions: Skin Flora Bacterial Reduction Post-product Application
Interventions: 3M CHG/IPA Prep Colorless, 3M CHG/IPA Prep Tint, ChloraPrep, Saline; Drug
Lead sponsor: Solventum US LLC; Industry
Eligibility: 18 Years and older
Enrollment: 171 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Bozeman, Montana

Conditions: Severe Alzheimer Disease
Interventions: GRF6019, Placebo; Drug · Other
Lead sponsor: Alkahest, Inc.; Industry
Eligibility: 60 Years to 95 Years
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019
U.S. locations: 6
States / cities: Gilbert, Arizona • Mesa, Arizona • Phoenix, Arizona + 3 more

Conditions: Osteoarthritis
Interventions: ACP, Placebo; Device · Other
Lead sponsor: Arthrex, Inc.; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2018
U.S. locations: 4
States / cities: Chicago, Illinois • Ann Arbor, Michigan • Columbia, Missouri + 1 more

Conditions: Subarachnoid Hemorrhage
Interventions: Normal Saline, Nicardipine; Drug
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 214 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2028
U.S. locations: 1
States / cities: Park Ridge, Illinois

Conditions: Pediatrics, Muscle Spasticity, Cerebral Palsy, Stroke
Interventions: botulinum toxin Type A, Normal Saline (Placebo); Biological · Drug
Lead sponsor: Allergan; Industry
Eligibility: 2 Years to 16 Years
Enrollment: 235 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 20
States / cities: Pasadena, California • Pomona, California • Aurora, Colorado + 15 more

Conditions: Critical Illness, Depressive Symptoms
Interventions: Ketamine (0.5 mg/kg), Normal Saline (0.9% NaCl); Drug · Other
Lead sponsor: Hospital Italiano de Buenos Aires; Other
Eligibility: 18 Years to 99 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Migraine, Migraine in Children
Interventions: 1/2 maintenance fluids, Ketorolac, Diphenhydramine, Prochlorperazine, bolus; Other · Drug
Lead sponsor: Dayton Children's Hospital; Other
Eligibility: 5 Years to 21 Years
Enrollment: 134 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Dayton, Ohio

Conditions: Exercise-Induced Laryngeal Obstruction, Dyspnea During Activity
Interventions: Ipratropium Bromide, Normal Saline (Placebo); Drug
Lead sponsor: Cook Children's Health Care System; Other
Eligibility: 8 Years to 17 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Prosper, Texas

Conditions: 22q13 Deletion Syndrome, Phelan-McDermid Syndrome
Interventions: Insulin-Like Growth Factor-1 (IGF-1), Normal saline; Drug
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 5 Years to 12 Years
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: New York, New York

Conditions: Herpes Zoster, Allergy and Immunology, Corona Virus Infection
Interventions: SHINGRIX (Zoster Vaccine REcombinant, Adjuvanted), Normal Saline; Biological · Drug
Lead sponsor: University of Oklahoma; Other
Eligibility: 65 Years to 100 Years
Enrollment: 217 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Spinal Cord Injury
Interventions: Zoledronic acid, normal saline 0.9%; Drug
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2018
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Beta Haemolytic Streptococcal Infection
Interventions: GBS III-TT, Tetanus and diptheria toxoids vaccine; Biological
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 667 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2008
U.S. locations: 3
States / cities: Augusta, Georgia • Pittsburgh, Pennsylvania • Houston, Texas

Conditions: Induced Labor
Interventions: 5% Dextrose (D5) in Normal Saline (NS), Lactate Ringer; Drug
Lead sponsor: Eastern Virginia Medical School; Other
Eligibility: 18 Years and older · Female only
Enrollment: 158 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Norfolk, Virginia

Conditions: Healthy Volunteer
Interventions: ANG-3777 (Therapeutic Dose), ANG-3777 (Supra-therapeutic Dose), Placebo, Moxifloxacin Hydrochloride; Drug
Lead sponsor: Angion Biomedica Corp; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 48 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Acute Kidney Injury, Ischemia Reperfusion Injury
Interventions: Valproic acid, Isotonic saline solution; Drug
Lead sponsor: Westat; Other
Eligibility: 18 Years to 80 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 4
States / cities: San Francisco, California • Denver, Colorado • Dallas, Texas + 1 more

Conditions: Mesothelioma
Interventions: Magnesium sulfate, Normal Saline; Drug
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 130 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Obesity
Interventions: Pramlintide (Amylin), Placebo (Normal Saline), 2 Metreleptin, Leptin plus Pramlintide; Drug
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 18 Years to 45 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2024
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Renal Failure Congenital, Congenital Renal Anomaly Nos, Renal Agenesis and Dysgenesis, Lower Urinary Tract Obstructive Syndrome
Interventions: Lactated Ringers Solution for Injection; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: Not listed
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2029
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Ischemic Stroke
Interventions: Normal saline; Other
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 110 Years
Enrollment: 81 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2019
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Sepsis
Interventions: Ascorbic Acid, Normal Saline; Drug · Other
Lead sponsor: Christiana Care Health Services; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Newark, Delaware

Conditions: Insulin Resistance, Prediabetic State, Non-Alcoholic Fatty Liver Disease, Overweight and Obesity
Interventions: Insulin human, Octreotide Acetate, Glucagon, Human Growth Hormone, Dexamethasone Oral, [6,6-2H2] D-glucose, 20% D-glucose (aq), BOOST Plus, Harvard Apparatus PHD ULTRA CP syringe pump, Yellow Springs Instruments (YSI) 2500 Biochemistry Glucose/Lactate Analyzer, Normal saline, Human albumin; Drug · Other · Dietary Supplement + 1 more
Lead sponsor: Columbia University; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Surgical Skin Preparation
Interventions: CHG/IPA Surgical skin preparation, Normal saline; Drug
Lead sponsor: Solventum US LLC; Industry
Eligibility: 18 Years and older
Enrollment: 154 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Sterling, Virginia

Search by objective public record fields.

Comparing Outcomes for Prontosan Versus Normal Saline for Negative Pressure Wound Therapy With Instillation

Saline Hypertonic in Preschoolers + CT

In-vivo Efficacy Study of Patient Preoperative Preps

A Study to Assess the Safety of GRF6019 Infusions in Subjects With Severe Alzheimer's Disease

Autologous Conditioned Plasma (ACP) Intra-articular (IA) Injections for Knee Osteoarthritis (OA)

Lumbar Drain With Intrathecal Nicardipine in Aneurysmal Subarachnoid Hemorrhage

BOTOX® Treatment in Pediatric Upper Limb Spasticity

Subanesthetic Ketamine Infusions for Depressive Symptoms in Intensive Care Unit Patients

Intravenous Fluids in Pediatric Migraine

Effect of Ipratropium Bromide on EILO

Clinical Trial in 22q13 Deletion Syndrome(Phelan-McDermid Syndrome)

Training the Innate Immune System Against SARS-CoV-2 (COVID-19) Using the Shingrix Vaccine in Nursing Home Residents

Zoledronic Acid in Acute Spinal Cord Injury

Prevention of GBS Colonization Via Immunity

Lactated Ringer's and Dextrose 5% vs Only Lactated Ringer's in Labor

Study Developed to Evaluate the Effect of ANG-3777 on QT/QTc Interval

Valproic Acid (VPA) for Acute Kidney Injury (AKI) in Liver Transplant Patients

MAGIC AKI: Magnesium for the Prevention of HIOC-Associated AKI

A Study of the Functional Magnetic Resonance Imaging Response to Leptin and Pramlintide

Serial Amnioinfusions as Regenerative Therapy for Pulmonary Hypoplasia

Bolus of Saline in Stroke

High Dose Intravenous Ascorbic Acid in Severe Sepsis

Dexamethasone/Pancreatic Clamp P&F

Efficacy Study of Patient Preoperative Preps In-vivo