- Conditions
- Monkeypox
- Interventions
- JYNNEOS
- Biological
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 229 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2025
- U.S. locations
- 8
- States / cities
- San Diego, California • Washington D.C., District of Columbia • Decatur, Georgia + 5 more
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Showing 1–6
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- Conditions
- Monkeypox
- Interventions
- JYNNEOS
- Biological
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Eligibility
- 12 Years to 50 Years
- Enrollment
- 450 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2024
- U.S. locations
- 17
- States / cities
- Birmingham, Alabama • Washington D.C., District of Columbia • Atlanta, Georgia + 13 more
- Conditions
- Monkeypox (Mpox)
- Interventions
- Jynneos, MVA-BN (Quail)
- Biological
- Lead sponsor
- Bavarian Nordic
- Industry
- Eligibility
- 18 Years to 49 Years
- Enrollment
- 970 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2026
- U.S. locations
- 10
- States / cities
- Ames, Iowa • Lenexa, Kansas • Rochester, New York + 7 more
- Conditions
- Vaccinia, Virus Diseases
- Interventions
- JYNNEOS (Smallpox and Monkeypox Vaccine, Live, Nonreplicating) suspension for subcutaneous injection, Phlebotomy, Research bronchoscopy, Skin punch biopsy, Bone marrow aspiration
- Biological · Procedure
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Systemic Inflammation, Immune Dysregulation, Injection Drug Use, HIV
- Interventions
- Metformin, Placebo, Jynneos, Capvaxvie
- Drug · Biological
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 18 Years to 64 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2029
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Smallpox
- Interventions
- Tecovirimat, Smallpox and Mpox Vaccine, Placebo
- Drug · Other
- Lead sponsor
- SIGA Technologies
- Industry
- Eligibility
- 18 Years to 42 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2027
- U.S. locations
- 2
- States / cities
- Omaha, Nebraska • Columbus, Ohio