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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Knee MRI Clear all
Completed Not applicable Interventional

Effect of Glucosamine on Joint Structure and Quality of Life (JOG)

NCT00377286
View directory record Official record
Conditions
Osteoarthritis
Interventions
Glucosamine (a dietary supplement), 16 oz lite lemonade
Dietary Supplement · Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
35 Years to 65 Years
Enrollment
201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 13, 2011 · Synced Sep 22, 2026, 2:55 AM EDT
Completed No phase listed Observational

Intra-articular Volumetric Assessment After Total Knee Arthroplasty

NCT02821325
View directory record Official record
Conditions
Hematoma
Interventions
MRI
Other
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 89 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Feb 25, 2018 · Synced Sep 22, 2026, 2:55 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Impact of Breast Cancer Treatment on Joint Health, Cartilage Composition, and Bone Structure in the Knee and Hand

NCT04876378
View directory record Official record
Conditions
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIA Breast Cancer AJCC v8, Anatomic Stage IIB Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8, Anatomic Stage IIIC Breast Cancer AJCC v8, Hormone Receptor Positive Breast Adenocarcinoma, Prognostic Stage I Breast Cancer AJCC v8, Prognostic Stage IA Breast Cancer AJCC v8, Prognostic Stage IB Breast Cancer AJCC v8, Prognostic Stage II Breast Cancer AJCC v8, Prognostic Stage IIA Breast Cancer AJCC v8, Prognostic Stage IIB Breast Cancer AJCC v8, Prognostic Stage III Breast Cancer AJCC v8, Prognostic Stage IIIA Breast Cancer AJCC v8, Prognostic Stage IIIB Breast Cancer AJCC v8, Prognostic Stage IIIC Breast Cancer AJCC v8
Interventions
Magnetic Resonance Imaging, Questionnaire Administration
Procedure · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
Up to 70 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 8, 2022 · Synced Sep 22, 2026, 2:55 AM EDT
Recruiting Not applicable Interventional

Evaluating Cryopreserved Osteochondral Allograft Cores for the Treatment of Osteochondral Lesions in the Knee

NCT06216756
View directory record Official record
Conditions
Osteochondral Defect
Interventions
osteochondral transplant on the femoral condyle
Procedure
Lead sponsor
AlloSource
Industry
Eligibility
12 Years to 60 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2031
U.S. locations
6
States / cities
Phoenix, Arizona • Los Angeles, California • Redwood City, California + 3 more
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Sep 22, 2026, 2:55 AM EDT
Terminated Not applicable Interventional

Visionaire: A Prospective Study

NCT01937572
View directory record Official record
Conditions
Osteoarthritis
Interventions
Visionaire system (Knee MRI), No Knee MRI
Other
Lead sponsor
The Hawkins Foundation
Other
Eligibility
18 Years to 100 Years
Enrollment
149 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 4, 2018 · Synced Sep 22, 2026, 2:55 AM EDT
Recruiting No phase listed Observational

Post-Stroke Sensory Reweighting on Walking and Balance Outcomes

NCT06727097
View directory record Official record
Conditions
Ischemic Stroke
Interventions
Posturography, Walking Speed, Instrumented 7M Timed UP and GO, Fall Event Records, MRI (3T)
Diagnostic Test · Other
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 22, 2026, 2:55 AM EDT
Completed Not applicable Interventional

T1Rho MRI Evaluation of Patellofemoral Changes After Tibial IM Nailing

NCT01879215
View directory record Official record
Conditions
Acute Tibial Fracture Requiring Intramedullary Nailing
Interventions
Intramedullary nailing of the tibia
Procedure
Lead sponsor
University of Pennsylvania
Other
Eligibility
21 Years to 50 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 21, 2020 · Synced Sep 22, 2026, 2:55 AM EDT
Completed Phase 4 Interventional Results available

Effect of Steroid Injections in a Knee With Osteoarthritis

NCT01230424
View directory record Official record
Conditions
Osteoarthritis (OA) of the Knee
Interventions
Triamcinolone Acetonide, 0.9% Sodium Chloride Injection as Placebo
Drug
Lead sponsor
Tufts Medical Center
Other
Eligibility
45 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 30, 2017 · Synced Sep 22, 2026, 2:55 AM EDT
Terminated No phase listed Observational

The Diagnostic Accuracy of the Clinical Examination

NCT03850470
View directory record Official record
Conditions
Musculoskeletal Pain, Musculoskeletal Injury
Interventions
clinical examination, MRI
Diagnostic Test · Other
Lead sponsor
High Point University
Other
Eligibility
18 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
High Point, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 26, 2021 · Synced Sep 22, 2026, 2:55 AM EDT
Completed Phase 2Phase 3 Interventional

A Placebo-Controlled Study of Collagen Hydrolysate in Subjects With Knee Osteoarthritis (OA)

NCT00536302
View directory record Official record
Conditions
Knee Osteoarthritis (OA)
Interventions
Collagen Hydrolysate, Placebo
Dietary Supplement
Lead sponsor
GELITA
Industry
Eligibility
49 Years to 90 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 5, 2009 · Synced Sep 22, 2026, 2:55 AM EDT
Completed Not applicable Interventional

Neural Correlates of Knee Sensorimotor Control in Patients With Patellofemoral Pain Syndrome

NCT04099004
View directory record Official record
Conditions
Patellofemoral Pain Syndrome, Patellofemoral Pain
Interventions
Neural Imaging
Other
Lead sponsor
Emory University
Other
Eligibility
7 Years to 40 Years · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
2
States / cities
Flowery Branch, Georgia • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 12, 2024 · Synced Sep 22, 2026, 2:55 AM EDT
Active, not recruiting Phase 4 Interventional

Corticosteroid Meniscectomy Randomized Trial

NCT04641351
View directory record Official record
Conditions
Osteoarthritis, Knee, Meniscus Tear, Meniscus; Degeneration, Synovitis
Interventions
Zilretta Injectable Product or Placebo
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
40 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 30, 2026 · Synced Sep 22, 2026, 2:55 AM EDT
Terminated Phase 4 Interventional

Knee Articular Cartilage Debridement in Conjunction With Partial Meniscectomy

NCT00613535
View directory record Official record
Conditions
Torn Meniscus
Interventions
Mechanical Debridement, Paragon T2, Lavage debridement, RF- based Debridement
Device · Procedure
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years to 60 Years
Enrollment
165 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
10
States / cities
Phoenix, Arizona • Los Angeles, California • Aurora, Colorado + 6 more
Source: ClinicalTrials.gov public record
Updated May 18, 2015 · Synced Sep 22, 2026, 2:55 AM EDT
Completed Phase 4 Interventional

A Comparative Study of Knee Systems

NCT01331278
View directory record Official record
Conditions
Osteoarthritis of the Knee
Interventions
Total Knee Arthroplasty with Custom Cutting Blocks, Total Knee Arthroplasty via Computer Assisted Surgery
Procedure
Lead sponsor
Foundation for Southwest Orthopedic Research
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 7, 2011 · Synced Sep 22, 2026, 2:55 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Knee Alignment Contributions to Anterior Cruciate Ligament (ACL) Injury

NCT00855023
View directory record Official record
Conditions
Knee Injuries
Interventions
Not listed
Lead sponsor
The Orthopaedic Center, Maryland
Other
Eligibility
18 Years to 45 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 17, 2020 · Synced Sep 22, 2026, 2:55 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Longitudinal Study of Osteoarthritis (OA) Disease Progression Measured by MRI, dGEMRIC, and Radiography

NCT00505297
View directory record Official record
Conditions
Osteoarthritis
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
40 Years and older · Female only
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 22, 2007 · Synced Sep 22, 2026, 2:55 AM EDT
Recruiting No phase listed Observational

Osteochondritis Dissecans of Knee Prospective Cohort

NCT02771496
View directory record Official record
Conditions
Osteochondritis Dissecans
Interventions
Other: observational only- no intervention
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
Not listed
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2074
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Sep 22, 2026, 2:55 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Long Term Outcomes of Osteochondral Allografts for Osteochondral Defects of the Knee

NCT02308358
View directory record Official record
Conditions
Outcomes of Allograft
Interventions
Not listed
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 29, 2023 · Synced Sep 22, 2026, 2:55 AM EDT
Active, not recruiting Phase 1 Interventional Accepts healthy volunteers

Impact of Mesenchymal Stem Cells in Knee Osteoarthritis

NCT03477942
View directory record Official record
Conditions
Musculoskeletal Pain, Knee Osteoarthritis, Cartilage Injury, Cartilage Degeneration
Interventions
Autologous Mesenchymal Stem Cells
Biological
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 60 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Sep 22, 2026, 2:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Obesity and Cartilage Compression in Knees

NCT04730557
View directory record Official record
Conditions
Obesity, Osteoarthritis, Knee Osteoarthritis
Interventions
Weight Loss
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 45 Years
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 5, 2024 · Synced Sep 22, 2026, 2:55 AM EDT
Recruiting Not applicable Interventional

Focused Extracorporeal Shockwave Therapy for Knee Arthritis

NCT05596591
View directory record Official record
Conditions
Bone Marrow Edema, Knee Osteoarthritis, Knee Pain Chronic
Interventions
Focused extracorporeal shockwave therapy
Device
Lead sponsor
Kessler Foundation
Other
Eligibility
30 Years to 80 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
Cedar Knolls, New Jersey • West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Sep 22, 2026, 2:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Total Knee Replacement Study Using Standard Cutting Guide vs Otismed MRI Generated Cutting Guide

NCT00837772
View directory record Official record
Conditions
Osteoarthritis of the Knee
Interventions
Standard cutting guide for TKA, Otismed MRI generated cutting guide for TKA
Device
Lead sponsor
Phoenix VA Health Care System
Federal
Eligibility
40 Years to 90 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2014
U.S. locations
2
States / cities
Phoenix, Arizona • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 5, 2016 · Synced Sep 22, 2026, 2:55 AM EDT
Completed No phase listed Observational

Diagnostic Value of Weight Bearing CT for Detecting Meniscal Tears

NCT04430829
View directory record Official record
Conditions
Meniscus Tear, Tibial
Interventions
Weight-Bearing CT arthrography, Knee MRI
Diagnostic Test
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated May 16, 2024 · Synced Sep 22, 2026, 2:55 AM EDT
Enrolling by invitation Phase 2 Interventional

Bio-Integrative, Fiber-Reinforced Kneebar for Treating Subchondral Insufficiency of the Knee

NCT06423378
View directory record Official record
Conditions
Subchondral Insufficiency Fracture
Interventions
OSSIOfiber® Trimmable Fixation Nails
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Sep 22, 2026, 2:55 AM EDT