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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Large Language Model Clear all
Completed Not applicable Interventional Results available

A Randomized Controlled Trial of Ambient Artificial Intelligence Scribe Technologies

NCT06792890
View directory record Official record
Conditions
Physician Workflow, Artificial Intelligence (AI)
Interventions
Use Nabla AI Scribe tool provided, Use AI Scribe tool provided by Vendor B
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
Not listed
Enrollment
238 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Sep 3, 2026, 10:12 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Planetary Health and Environmental Justice in Construction Career Education

NCT07315919
View directory record Official record
Conditions
Health Knowledge, Environmental Exposure, Attitude, Practice
Interventions
Community-Centered Design Curriculum with EJT, Traditional Technical Curriculum
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
14 Years to 18 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Sep 3, 2026, 10:12 PM EDT
Recruiting Not applicable Interventional

Multi-modal Large Language Model-Empowered Talk Therapy for Older Adults With ADRD

NCT07499570
View directory record Official record
Conditions
Mild Cognitive Impairment, Dementia, BPSD, BPSD (Behavioral and Psychological Symptoms of Dementia), Reminiscence Therapy
Interventions
Smart Virtual Reminiscence Therapy, Music Therapy
Device · Other
Lead sponsor
Indiana University
Other
Eligibility
65 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 3, 2026, 10:12 PM EDT
Not yet recruiting Not applicable Interventional

A Feasibility and Acceptability Study of a Large Language Model-based Chatbot for Brief Alcohol Intervention Among Emerging Adults

NCT07214831
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Large language model-based chatbot brief alcohol intervention session
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 29 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 21, 2025 · Synced Sep 3, 2026, 10:12 PM EDT
Completed Not applicable Interventional

ANCHOR Validation Trial in High-Risk Multidisciplinary Care

NCT07597499
View directory record Official record
Conditions
High-Risk Multidisciplinary Care, Clinical Decision Support, Artificial Intelligence-Assisted Care, Telemedicine
Interventions
Gemini 3.1 Pro with Safety Prompt, ANCHOR Clinical AI Verification Layer (with Gemini 3.1 Pro)
Behavioral
Lead sponsor
Waymark
Industry
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Sep 3, 2026, 10:12 PM EDT
Not yet recruiting Not applicable Interventional

Digital Coach to Support Exposure Therapy Homework for Anxious Youth

NCT07666672
View directory record Official record
Conditions
Anxiety Disorders, OCD
Interventions
BraveBot, Self-Guided Exposure Therapy Homework
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
12 Years to 22 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
3
States / cities
Belmont, Massachusetts • Boston, Massachusetts • Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Sep 3, 2026, 10:12 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Relationship Between Child Language Proficiency and Language of Treatment on the Outcomes of Bilingual Children with Developmental Language Disorder

NCT06085300
View directory record Official record
Conditions
Developmental Language Disorder, Language Impairment
Interventions
Sentence recast
Behavioral
Lead sponsor
University of Houston
Other
Eligibility
4 Years to 6 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 13, 2025 · Synced Sep 3, 2026, 10:12 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

RCT of HeartBot in Women

NCT07416734
View directory record Official record
Conditions
Participants Must be Women Aged 25 Years or Older, Participants Should Have no Self-reported History of Heart Disease or Stroke, Participants Should Have no Terminal Illness or Diagnosed Cognitive Impairment, Including Alzheimer's Disease, Participants Should Not be a Healthcare Professionals or Healthcare Trainees, Participants Should Not be Employed in the Healthcare Field, Participants Should Reside in the United States and be a University of California, San Francisco Health Patient, Participants Should Possess a Smartphone With an Active Data Plan or Access to Wi-Fi
Interventions
HeartBot II Program, Waitlist Control
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
25 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Sep 3, 2026, 10:12 PM EDT
Recruiting Not applicable Interventional

Targeted Artificial Intelligence Language mOdel Recommendations for Heart Failure (TAILOR-HF)

NCT07337577
View directory record Official record
Conditions
Heart Failure
Interventions
LLM-GDMT Clinical Decision Support Tool
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 30, 2026 · Synced Sep 3, 2026, 10:12 PM EDT
Recruiting Not applicable Interventional

Postpartum Education Via Artificial Intelligence for Recovery and Loneliness: A Randomized Controlled Trial

NCT07223736
View directory record Official record
Conditions
Pelvic Floor Disorder, Loneliness, Postpartum, Mental Health, Depression, Peritraumatic Distress, Women, Artificial Intelligence (AI), Chatbot
Interventions
Generative artificial intelligence (genAI) postpartum chatbot, Standard of Care (SOC)
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older · Female only
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Sep 3, 2026, 10:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Conversations With AI Chatbots Increase Short-Term Vaccine Intentions But Do Not Outperform Standard Public Health Messaging

NCT07132125
View directory record Official record
Conditions
HPV Vaccination Intent
Interventions
Default-style LLM chatbot, Conversational-style LLM chatbot, Public health informational materials
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
930 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 19, 2025 · Synced Sep 3, 2026, 10:12 PM EDT
Active, not recruiting Not applicable Interventional

Evaluating the Impacts of a Well-Being Mobile App in Mexico

NCT07109648
View directory record Official record
Conditions
Mental Health, Wellbeing
Interventions
Access to app
Behavioral
Lead sponsor
Raissa Fabregas
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
4,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Sep 3, 2026, 10:12 PM EDT
Not yet recruiting Not applicable Interventional

SAFE.AI: Developing and Testing an AI-based Hybrid Chatbot for Financial Empowerment in Rural Cancer Care

NCT07410689
View directory record Official record
Conditions
Cancer, Financial Toxicity
Interventions
Rule-Based Chatbot, Hybrid Chatbot
Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Sep 3, 2026, 10:12 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Digital Tools to Support Healthcare Decision Making

NCT07485725
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Project 3, Phase 2: Clinical Trial
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
60 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
3
States / cities
Tallahassee, Florida • Champaign, Illinois • New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Sep 3, 2026, 10:12 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

OpenEvidence Safety and Comparative Efficacy of Four LLM's in Clinical Practice

NCT07199231
View directory record Official record
Conditions
AI (Artificial Intelligence), Large Language Model, Generative Artificial Intelligence
Interventions
AI clinical reference tool
Other
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 3, 2026, 10:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

DHL Survey on Generative AI for MyChart Messaging

NCT06108037
View directory record Official record
Conditions
Communication
Interventions
Generative AI for electronic communication and disclosure
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
1,454 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 12, 2023 · Synced Sep 3, 2026, 10:12 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Piloting a Generative Artificial Intelligence Chatbot in a Mobile Weight Loss Program

NCT07534254
View directory record Official record
Conditions
Overweight and/or Obesity
Interventions
AGILE Intervention, Chatbot
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 39 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Sep 3, 2026, 10:12 PM EDT
Withdrawn Not applicable Interventional

Effect of Large Language Model in Assisting Discharge Summary Notes Writing for Hospitalized Patients

NCT06263855
View directory record Official record
Conditions
Large Language Model
Interventions
CURE
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Sep 3, 2026, 10:12 PM EDT
Recruiting Not applicable Interventional

Generative AI Patient Education Module for Breast Oncology

NCT07512271
View directory record Official record
Conditions
Breast Cancer, Metastatic Breast Cancer, Carcinoma of the Breast
Interventions
Survey (Participant), OpenEvidence CareConnect, Survey (Provider)
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Sep 3, 2026, 10:12 PM EDT
Completed Not applicable Interventional

Enhancing Interdisciplinary Understanding of Ophthalmology Notes Through a Local Large Language Model

NCT06624605
View directory record Official record
Conditions
Communication, Artificial Intelligence (AI), Artificial Intelligence Technology, Interdisciplinary Communication
Interventions
Large Language Model-generated Plain Language Summary of Ophthalmology notes
Other
Lead sponsor
John J Chen
Other
Eligibility
18 Years and older
Enrollment
851 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 2, 2024 · Synced Sep 3, 2026, 10:12 PM EDT
Active, not recruiting Not applicable Interventional

Better Real-time Information on Documentation of Goals of Care for Engagement in Serious Illness Communication

NCT07147023
View directory record Official record
Conditions
Advanced Cancer, Cancer, End of Life
Interventions
LLM SIC Summary Email
Other
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 3, 2026, 10:12 PM EDT
Enrolling by invitation Not applicable Interventional

Effectiveness of a Large Language Model-Based Educational Tool on Visual Field Test Reliability in Glaucoma Patients

NCT07327242
View directory record Official record
Conditions
Glaucoma, Eye Disorders, Visual Fields, Visual Field Tests
Interventions
LLM-based Education
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Sep 3, 2026, 10:12 PM EDT
Completed Not applicable Interventional

A Megastudy of Single-Session Interventions for Depression

NCT06856668
View directory record Official record
Conditions
Depression - Major Depressive Disorder
Interventions
Behavioral Activation (Action Brings Change Project 10-Minute Version), Mindful Acceptance, Moral Elevation, Mindful Attention Skills, 5 Habits to Beat Depression, Interactive Cognitive Reappraisal, Expressive Writing (AI-supported), Inner Child Healing Walk, Savoring Strategies, Personalized Intervention Recommender, Dialectical Behavioral Therapy Skills, All about Trout, Reframing Negative Thoughts
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
7,505 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 26, 2025 · Synced Sep 3, 2026, 10:12 PM EDT
Recruiting Not applicable Interventional

Evaluating Conversational Artificial Intelligence for Depression Management

NCT07105397
View directory record Official record
Conditions
Major Depressive Disorder (MDD)
Interventions
Conversational AI system vs Usual Care
Other
Lead sponsor
George Mason University
Other
Eligibility
18 Years to 85 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Sep 3, 2026, 10:12 PM EDT