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ClinicalTrials.gov public records Last synced Nov 15, 2026, 1:49 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 1,020 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Laser therapy Clear all

Conditions: Diabetic Macular Edema
Interventions: intravitreal injection of ranibizumab, peripheral laser, intravitreal injection of triamcinolone acetonide, macular laser; Drug · Procedure
Lead sponsor: Retina Associates of Florida, P.A.; Other
Eligibility: 18 Years and older
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Cervical Carcinoma, Dyspareunia, Endometrial Carcinoma, Ovarian Carcinoma, Vaginal Carcinoma, Vaginal Dryness, Vulvar Carcinoma
Interventions: Laser Therapy, Questionnaire Administration, Sham Intervention; Procedure · Other
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: Female only
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 4
States / cities: Baltimore, Maryland • Rochester, Minnesota • Fargo, North Dakota + 1 more

Conditions: Critical Limb Ischemia
Interventions: Angioplasty, Laser atherectomy; Procedure
Lead sponsor: Baylor Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 3
States / cities: Dallas, Texas • Plano, Texas

Conditions: Lung Carcinoid Tumor, Lung Non-Small Cell Carcinoma, Metastatic Lung Carcinoma, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8
Interventions: Cone-Beam Computed Tomography, Conventional Surgery, Laser Ablation; Procedure
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Refractive Errors
Interventions: WAVEFRONT- GUIDED LASIK ENHANCEMENT, CONVENTIONAL LASIK ENHANCEMENT; Procedure
Lead sponsor: Walter Reed Army Medical Center; Federal
Eligibility: 21 Years and older
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2008
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Prostate Cancer
Interventions: Focal Laser Ablation; Procedure
Lead sponsor: Jonsson Comprehensive Cancer Center; Other
Eligibility: 40 Years to 85 Years · Male only
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Aging
Interventions: Medx Console System, Sham Medx Console System, Vielight 810 intranasal stand alone unit, Sham Vielight 810 intranasal stand alone unit; Device
Lead sponsor: University of Florida; Other
Eligibility: 65 Years to 89 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2026
U.S. locations: 2
States / cities: Tucson, Arizona • Gainesville, Florida

Conditions: Acne Scars - Mixed Atrophic and Hypertrophic
Interventions: MIRIA Laser; Device
Lead sponsor: AVAVA, Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 3
States / cities: Miami, Florida • Waltham, Massachusetts • New York, New York

Conditions: Diabetic Peripheral Neuropathy
Interventions: Erchonia FX-635, Placebo Laser; Device
Lead sponsor: Erchonia Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 4
States / cities: Mesa, Arizona • Costa Mesa, California • Hialeah, Florida + 1 more

Conditions: Varicose Veins, Venous Insufficiency
Interventions: VNUS RF ClosureFAST, VenaCure EVLT NeverTouch; Device
Lead sponsor: Angiodynamics, Inc.; Industry
Eligibility: 18 Years to 80 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 6
States / cities: Sacramento, California • Bradenton, Florida • Melrose Park, Illinois + 3 more

Conditions: Atrial Fibrillation, Paroxysmal or Persistent, Atrial Fibrillation and Flutter, Atrial Flutter Typical
Interventions: VARIPULSE™ catheter ablation; Device
Lead sponsor: Vivek Reddy; Other
Eligibility: 18 Years and older
Enrollment: 141 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: New York, New York

Conditions: Myopia, Astigmatism
Interventions: Ray-Tracing Guided LASIK, Keratorefractive Lenticule Extraction (KLEx), WaveFront Optimized LASIK, Topography Guided LASIK; Device
Lead sponsor: Hoopes Vision; Other
Eligibility: 22 Years to 50 Years
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Draper, Utah

Conditions: Rhytids, Skin Laxity
Interventions: 2,910 nm mid-infrared erbium-doped fluoride fiber glass laser (UltraClear, Acclaro Medical); Device
Lead sponsor: FA Corporation; Industry
Eligibility: 45 Years to 85 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Edina, Minnesota

Conditions: Post Concussion Syndrome
Interventions: Sensorimotor Multi-axis Automated Rotational Therapy (SMART) utilizing GyroStim device, Physical therapy and speech therapy/cognitive rehabilitation therapy; Device · Other
Lead sponsor: Neuroscience Group; Other
Eligibility: 18 Years and older
Enrollment: 128 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Appleton, Wisconsin

Conditions: Urinary Calculi
Interventions: Laser lithotripsy (SP TLF), Laser lithotripsy (Ho:YAG); Device
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years and older
Enrollment: 62 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2024
U.S. locations: 2
States / cities: Rochester, New York

Conditions: Peripheral Neuropathy
Interventions: Diode Laser fiber type Selective Stimulator, ZTlido 1.8 % Topical System, PeriCam PSI NR, Medoc Quantitative Sensory Testing, Inactive Topical System; Procedure · Drug · Diagnostic Test + 1 more
Lead sponsor: University of Utah; Other
Eligibility: 18 Years and older
Enrollment: 77 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 2
States / cities: Palo Alto, California • Salt Lake City, Utah

Conditions: Scars
Interventions: Lumenis fractional carbon dioxide laser; Device
Lead sponsor: Moy-Fincher Medical Group; Other
Eligibility: 18 Years to 70 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Back Pain
Interventions: Treatment with BTL-043, BTL-899; Device
Lead sponsor: BTL Industries Ltd.; Industry
Eligibility: 22 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 4
States / cities: Scottsdale, Arizona • Fort Myers, Florida • Columbus, Ohio + 1 more

Conditions: Twin Twin Transfusion Syndrome
Interventions: Selective Laser Photocoagulation of Communicating Vessels; Device
Lead sponsor: University of South Florida; Other
Eligibility: 18 Years to 55 Years · Female only
Enrollment: 77 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Actinic Keratoses, Aging, Non-Melanoma Skin Cancer
Interventions: Fractionated Laser Resurfacing; Device
Lead sponsor: Wright State University; Other
Eligibility: 60 Years and older
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2028
U.S. locations: 1
States / cities: Dayton, Ohio

Conditions: Onychomycosis
Interventions: light therapy; Device
Lead sponsor: Nomir Medical Technologies; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Southborough, Massachusetts

Conditions: Melasma
Interventions: Fractional 1927nm Low-Powered Diode Laser, Topical Cysteamine; Device · Other
Lead sponsor: UnionDerm; Other
Eligibility: 18 Years to 74 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Glaucoma
Interventions: Dual-Treatment Direct Selective Laser Trabeculoplasty (DSLT); Device
Lead sponsor: Twin Cities Eye Consultants; Other
Eligibility: 40 Years and older
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Coon Rapids, Minnesota

Conditions: Spider Veins
Interventions: Nd:YAG laser; Device
Lead sponsor: Cutera Inc.; Industry
Eligibility: 20 Years to 75 Years
Enrollment: 4 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Naperville, Illinois

Search by objective public record fields.

Ranibizumab and Peripheral Scatter Laser in Patients With Diabetic Macular Edema and Peripheral Nonperfusion

Fractional CO2 Laser Therapy in Minimizing Genitourinary Syndrome of Menopause in Gynecological Cancer Survivors

Laser Atherectomy Versus Angioplasty for the Treatment of Critical Limb Ischemia

Bronchoscopic Laser Ablation of Peripheral Lung Tumors

A Prospective Comparison of Alcon LADARVision Wavefront-guided LASIK Enhancement and Conventional LASIK Enhancement for the Correction of Residual Refractive Errors Following LASIK Procedures

Focal Laser Ablation of Prostate Cancer: A Feasibility Study Using MRI/US Image Fusion for Guidance

Pilot Intervention With Near Infrared Stimulation

The MIRIA Acne Scar Study

An Evaluation of the Effect of Low Level Laser Therapy on Diabetic Peripheral Neuropathy Pain

Comparison Study for Safety and Efficacy of Two Devices for the Treatment of the Great Saphenous Vein

Versatility of a Circular Multielectrode Catheter in the Individualized Recognition & Treatment of Atrial Fibrillation and Related Arrhythmias Using Pulsed Field Energy

A Three-Phase Contralateral Comparison of Ray-Tracing Guided LASIK Versus Three Other Refractive Surgery Platforms to Correct Myopia or Myopia With Astigmatism

Safety and Efficacy of 2910 nm Fiber Laser Resurfacing and Laser-Coring

GyroStim for Post Concussion Syndrome

SP TLF Versus Ho:YAG Laser

Diode Laser as a Biomarker for Neuropathic Pain of Peripheral Origin.

Burn Scar Appearance After Treatment With Fractional Carbon Dioxide (CO2) Laser

Safety and Efficacy of the BTL-043 and BTL-899 Devices in Alleviating Back Pain

Selective Laser Photocoagulation of Communicating Vessels in Twin-Twin Transfusion Syndrome

Effectiveness of Fractionated Laser Resurfacing to Protect Geriatric Skin From Actinic Neoplasia

Using Light Therapy to Treat Toe Nail Fungus

Combination Topical Cysteamine and Fractional 1927nm Low-Powered Diode Laser for Treatment of Facial Melasma

Glaucoma Laser Assessment of Stability and Sustainability

A Clinical Evaluation of the Treatment of Spider Veins on the Ankles