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ClinicalTrials.gov public records Last synced Nov 15, 2026, 2:14 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 73–96 of 1,020 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Laser therapy Clear all

Conditions: Lichen Planus Pigmentosus
Interventions: CO2 fractional laser; Device
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Retinoblastoma, Retinal Neoplasms
Interventions: Carboplatin, VP-16, Local Surgery, Cryotherapy, Laser hyperthermia; Drug · Procedure
Lead sponsor: Ann & Robert H Lurie Children's Hospital of Chicago; Other
Eligibility: Not listed
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1996 – 2006
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Age Related Macular Degeneration
Interventions: ranibizumab; Drug
Lead sponsor: The New York Eye & Ear Infirmary; Other
Eligibility: 51 Years to 90 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2012
U.S. locations: 1
States / cities: New York, New York

Conditions: Benign Pigmented Lesions
Interventions: GentleMax system; Device
Lead sponsor: Syneron Medical; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2013
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Chronic Knee Pain
Interventions: Photobiomodulation therapy (PBM) device, Sham PBM device; Device
Lead sponsor: University of Florida; Other
Eligibility: 50 Years to 99 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Healthy Participants, Mild Cognitive Impairment
Interventions: LLLT, Placebo; Device
Lead sponsor: University of Texas at Austin; Other
Eligibility: 45 Years and older
Enrollment: 91 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Edematous Fibrosclerotic Panniculopathy (EFP), Cellulite
Interventions: CCH-aaes, Compression, Cold Packs, Arnica Gel, INhance®, PDL; Drug · Other
Lead sponsor: Endo USA Inc., a Keenova Therapeutics Company; Industry
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 48 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 8
States / cities: Scottsdale, Arizona • Sacramento, California • San Diego, California + 5 more

Conditions: Oral Complications of Radiation Therapy, Stage I Laryngeal Cancer, Stage II Laryngeal Cancer
Interventions: laser therapy, questionnaire administration; Procedure · Other
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: Not listed
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2016
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Hyperopia, Myopia, Astigmatism
Interventions: LASIK and PRK; Procedure
Lead sponsor: Edward E. Manche; Other
Eligibility: 21 Years to 60 Years
Enrollment: 137 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2022
U.S. locations: 1
States / cities: Stanford, California

Conditions: Low-grade Glioma, Recurrent Low Grade Glioma, Low Grade Glioma of Brain, Pediatric Cancer
Interventions: Laser Interstitial Thermal Therapy (LITT), Magnetic resonance imaging (MRI), Questionnaires; Device · Procedure · Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 2 Years to 25 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Surgery
Interventions: Low Level Laser Therapy; Device
Lead sponsor: University of Toledo Health Science Campus; Other
Eligibility: 18 Years to 85 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Toledo, Ohio

Conditions: Diabetic Peripheral Neuropathy
Interventions: Erchonia® FX-635™, Placebo Laser; Device
Lead sponsor: Erchonia Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Mesa, Arizona

Conditions: Body Contouring
Interventions: Erchonia ML Scanner (MLS), Sham device; Device
Lead sponsor: Erchonia Corporation; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 72 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2008
U.S. locations: 3
States / cities: Palm Beach Gardens, Florida • Marion, Indiana • Bloomfield Hills, Michigan

Conditions: Diabetic Retinopathy
Interventions: Laser Photocoagulation, Bevacizumab; Procedure · Drug
Lead sponsor: Jaeb Center for Health Research; Other
Eligibility: 18 Years and older
Enrollment: 121 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 34
States / cities: Loma Linda, California • Palm Springs, California • Santa Barbara, California + 28 more

Conditions: Barrett's Esophagus With Dysplasia
Interventions: Mucosal Impedance, Research Biopsies, Volumetric Laser Endomicroscopy; Device · Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 90 Years
Enrollment: 53 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2022
U.S. locations: 2
States / cities: Rochester, Minnesota • New York, New York

Conditions: Hyperopia, Hyperopic Astigmatism
Interventions: riboflavin ophthalmic solution, 0% dextran, UVA Irradiation (30 mW/cm2 for 2 minutes continuous UVA), UVA Irradiation (30 mW/cm2 for 3 minutes pulsed UVA with an on/off cycle of 2 seconds UVA on/1 second UVA off), Laser-assisted in situ keratomileusis; Drug · Device · Procedure
Lead sponsor: Glaukos Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 5
States / cities: San Diego, California • Waltham, Massachusetts • Teaneck, New Jersey + 2 more

Conditions: Wrinkles
Interventions: Laser treatment, High-intensity focused ultrasound; Procedure · Device
Lead sponsor: Northwestern University; Other
Eligibility: 35 Years to 60 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2024
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Peri-orbital Wrinkles, Peri-oral Wrinkles
Interventions: Illuiminage ® Diode Laser; Device
Lead sponsor: Cynosure, Inc.; Industry
Eligibility: 35 Years to 60 Years · Female only
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Westford, Massachusetts

Conditions: Lung Cancer
Interventions: HPPH; Drug
Lead sponsor: Roswell Park Cancer Institute; Other
Eligibility: 18 Years to 120 Years
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2014
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Tattoo Removal
Interventions: enLighten Laser; Device
Lead sponsor: Cutera Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 8 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Stamford, Connecticut

Conditions: Benign Prostatic Hyperplasia (BPH)
Interventions: Greenlight XPS Laser, BiVAP Saline Vaporization of the prostate; Device
Lead sponsor: Brooklyn Urology Research Group; Other
Eligibility: 18 Years and older · Male only
Enrollment: 66 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Brooklyn, New York

Conditions: Diabetic Retinopathy
Interventions: Laser Treatment; Procedure
Lead sponsor: National Eye Institute (NEI); NIH
Eligibility: 18 Years and older
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2007
U.S. locations: 2
States / cities: Bethesda, Maryland

Conditions: Rosacea
Interventions: Azelaic acid, Nd:Yag laser; Drug · Device
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Prostate Cancer, Lower Urinary Tract Symptoms
Interventions: Holmium Laser Enucleation of Prostate (HoLEP); Procedure
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2035
U.S. locations: 1
States / cities: Kansas City, Kansas

Search by objective public record fields.

Fractional CO2 Laser for the Treatment of Lichen Planus Pigmentosus

Chemotherapy Treatment for Children With Intraocular Germ-Line Retinoblastoma

Serial Retinal Thickness Changes And Scotoma Size Measured With Lucentis Therapy

Picosecond Laser for Ttreatment of Benign Pigmented Lesions

Effects of Photobiomodulation on Inflammation and Chronic Pain in Knee Osteoarthritis (EPIC-KO)

Cognitive Enhancement Through Transcranial Laser Therapy

Effects of Mitigation Treatments on Bruising of CCH-aaes Treatment of Buttock Cellulite

Pulsed Dye Laser in Treating Patients With Post Radiation Dysphonia

A Comparison of Fellow Eyes Undergoing LASIK or PRK With a Wavefront-guided Excimer Laser Versus a Wavefront-optimized Excimer Laser

Efficacy of Laser Interstitial Thermal Therapy in Young Persons With Low-grade Glioma

Assessment of Low Level Laser Therapy for Late Postoperative Pain After Lumbar Fusion Surgery

Study of Low Level Laser Therapy to Treat Diabetic Peripheral Neuropathy Foot Pain

Study of Low Level Laser Therapy for Body Contouring

A Phase 2 Evaluation of Anti-VEGF Therapy for Diabetic Macular Edema: Bevacizumab (Avastin)

Characterization of the Neo-squamous Epithelial Barrier

Safety and Efficacy of Corneal Collagen Cross-linking Following LASIK for Treatment of Hyperopia and Hyperopic Astigmatism

Fractional Laser vs. Ultrasound for Periorbital Wrinkles

Treatment of Periorbital and Perioral Wrinkles With the Applications of the Iluminage Diode Laser

Photodynamic Therapy Using HPPH in Treating Patients With Stage 0 Non-Small Cell Lung Cancer

A Study of a Novel Multi-Wavelength Laser for Tattoo Removal

Phase 4 Study of Greenlight XPS Laser Versus BiVAP Saline Vaporization of the Prostate in Men With Symptomatic Benign Prostatic Hyperplasia

Pilot Study of Laser Photocoagulation Therapy for Diabetic Macular Edema

Combination Gel and Vascular ND in Mild to Moderate Rosacea

HoLEP Prior to Radiation Therapy for Patients With LUTS/Retention and Concurrent Prostate Cancer