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ClinicalTrials.gov public records Last synced Oct 15, 2026, 3:22 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 433–456 of 1,059 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Laser treatment Clear all
Recruiting Not applicable Interventional

Optical Coherence Tomography Guided Transepithelial Phototherapeutic Keratectomy

NCT01243931
View directory record Official record
Conditions
Corneal Opacity
Interventions
OCT-guided laser phototherapeutic keratectomy
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2026
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Feb 12, 2024 · Synced Oct 15, 2026, 3:22 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Fractional CO2 Laser Therapy Versus 4% Topical Lidocaine Gel for Dyspareunia in Breast Cancer Survivors

NCT03257670
View directory record Official record
Conditions
Dyspareunia
Interventions
4% Topical Lidocaine Gel, CO2RE fractional laser therapy
Drug · Device
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older · Female only
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 28, 2021 · Synced Oct 15, 2026, 3:22 AM EDT
Recruiting Not applicable Interventional

Transcranial Photobiomodulation (tPBM) in Alzheimer's Disease Study

NCT07224607
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
Photobiomodulation
Device
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
55 Years to 89 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 15, 2026, 3:22 AM EDT
Completed Phase 3 Interventional

Effectiveness and Safety Trial of a New Ischemic Stroke Treatment Within 24 Hours From Stroke Onset (NEST-2)

NCT00419705
View directory record Official record
Conditions
Ischemic Stroke
Interventions
NeuroThera® Laser System
Device
Lead sponsor
PhotoThera, Inc
Industry
Eligibility
40 Years to 90 Years
Enrollment
660 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
51
States / cities
Fort Smith, Arkansas • Berkeley, California • Encinitas, California + 45 more
Source: ClinicalTrials.gov public record
Updated Jun 9, 2011 · Synced Oct 15, 2026, 3:22 AM EDT
Not listed Phase 1 Interventional

Bioburden Reduction of Diabetic Foot Ulcer

NCT00776854
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
Noveon laser
Device
Lead sponsor
Nomir Medical Technologies
Industry
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Waltham, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 21, 2008 · Synced Oct 15, 2026, 3:22 AM EDT
Withdrawn Not applicable Interventional

Laser Therapy in the Treatment of Post Thoracotomy Pain; A Pilot Study

NCT00623909
View directory record Official record
Conditions
Laser Therapy, Post Thoracotomy Pain
Interventions
AvicennaTM class IV laser application
Device
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
25 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 7, 2017 · Synced Oct 15, 2026, 3:22 AM EDT
Active, not recruiting No phase listed Observational

Multicenter Phenotype-Genotype Analysis of Vascular Stains to Optimize Treatment Utilizing Optical Coherence Tomography

NCT04772911
View directory record Official record
Conditions
Vascular Stains
Interventions
Optical Coherence Tomography (OCT)
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
Not listed
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
2
States / cities
Irvine, California • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Oct 15, 2026, 3:22 AM EDT
Withdrawn Not applicable Interventional

Early Carbon Dioxide Laser Therapy for Alleviation of Incisional Scar Burden

NCT03306628
View directory record Official record
Conditions
Skin Scarring
Interventions
CO2 Laser Administration
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
21 Years to 80 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 6, 2020 · Synced Oct 15, 2026, 3:22 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Childhood Alopecia Areata Study Using the 308-nm Excimer Laser

NCT01736007
View directory record Official record
Conditions
Alopecia Areata
Interventions
308-nm excimer laser to alopecia patch, Liquid light guide tip on laser
Device
Lead sponsor
Phoenix Children's Hospital
Other
Eligibility
6 Years to 17 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Oct 31, 2014 · Synced Oct 15, 2026, 3:22 AM EDT
Recruiting Not applicable Interventional

Facial Papules in Frontal Fibrosing Alopecia (FFA)

NCT07340671
View directory record Official record
Conditions
Frontal Fibrosing Alopecia
Interventions
Cutera® 1726 nm laser system
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jul 24, 2026 · Synced Oct 15, 2026, 3:22 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Treatment of Lower Extremity Spider Veins With Excel V

NCT01362192
View directory record Official record
Conditions
Telangiectasis, Spider Veins
Interventions
532 nm KTP Excel V Laser, manufactured by Cutera, Inc.
Device
Lead sponsor
Cutera Inc.
Industry
Eligibility
21 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Ardmore, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 29, 2015 · Synced Oct 15, 2026, 3:22 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Fractional Photothermolysis for Hair Follicle Induction

NCT03382184
View directory record Official record
Conditions
Alopecia
Interventions
Fraxel Dual laser, Halo laser
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 90 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Oct 15, 2026, 3:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Prospective Evaluation of Contrast Sensitivity and Disability Glare in Refractive Surgery, a Sub-Study of: Initial Evaluation of Excimer Laser Keratorefractive Surgery in U.S. Army Personnel (WU # 2335-99)

NCT00413868
View directory record Official record
Conditions
Myopia
Interventions
LASIK, PRK, Small target contrast sensitivity and disability glare
Procedure · Behavioral
Lead sponsor
Walter Reed Army Medical Center
Federal
Eligibility
21 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 1, 2008 · Synced Oct 15, 2026, 3:22 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Clinical Evaluation to Assess the Safety and Efficacy of GentleMax Pro™/GentleMax Pro Plus™

NCT04975243
View directory record Official record
Conditions
Unwanted Fine Facial Hair
Interventions
GentleMax Pro Plus 755nm and 1064nm laser system
Device
Lead sponsor
Candela Corporation
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Marlborough, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 9, 2023 · Synced Oct 15, 2026, 3:22 AM EDT
Terminated Not applicable Interventional Results available

Feasibility Study on LITT for Medical Refractory Epilepsy

NCT02820740
View directory record Official record
Conditions
Epilepsy
Interventions
NeuroBlate System
Device
Lead sponsor
Monteris Medical
Industry
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
5
States / cities
Phoenix, Arizona • New Haven, Connecticut • Kansas City, Kansas + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 12, 2024 · Synced Oct 15, 2026, 3:22 AM EDT
Completed Not applicable Interventional Results available

The Effect of the Erchonia GVL Low Level Laser Therapy on Neck and Shoulder Pain

NCT04895618
View directory record Official record
Conditions
Musculoskeletal Pain
Interventions
Erchonia GVL
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
18 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
3
States / cities
West Covina, California • Largo, Florida • White Plains, New York
Source: ClinicalTrials.gov public record
Updated Aug 21, 2023 · Synced Oct 15, 2026, 3:22 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

The Revitalize Study in Older Adults at Risk for Alzheimer's Disease

NCT04018092
View directory record Official record
Conditions
Cognitive Aging, Alzheimer Disease, Protection Against
Interventions
Active NIR-PBM, Sham NIR-PBM
Device
Lead sponsor
University of Florida
Other
Eligibility
65 Years to 89 Years
Enrollment
168 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
2
States / cities
Tucson, Arizona • Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 15, 2026, 3:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Laser Treatment of Tattoos With Pico Laser

NCT02146807
View directory record Official record
Conditions
Unwanted Tattoos
Interventions
Picosecond Laser system
Device
Lead sponsor
Syneron Medical
Industry
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2013
U.S. locations
3
States / cities
Washington D.C., District of Columbia • New York, New York • Ardmore, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 26, 2015 · Synced Oct 15, 2026, 3:22 AM EDT
Not yet recruiting Phase 2 Interventional

Rapamycin Dose-Ranging Efficacy Study in Port Wine Stains

NCT07436611
View directory record Official record
Conditions
Port Wine Stains
Interventions
Rapamycin cream, Pulsed dyed laser
Drug · Procedure
Lead sponsor
AFT Pharmaceuticals, Ltd.
Industry
Eligibility
Up to 10 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Corpus Christi, Texas
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 15, 2026, 3:22 AM EDT
Recruiting Not applicable Interventional

Decreasing Emergence Agitation With Personalized Music

NCT05044832
View directory record Official record
Conditions
Surgical Procedure, Unspecified
Interventions
Personalized Music
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
3 Years to 9 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
Stanford, California • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 22, 2024 · Synced Oct 15, 2026, 3:22 AM EDT
Recruiting Phase 1 Interventional

Cryospray Therapy for Benign Airway Stenosis

NCT06085209
View directory record Official record
Conditions
Stenosis Trachea
Interventions
The truFreeze Spray Cryotherapy, Ballon dilation, Radial Incision
Device
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Oct 15, 2026, 3:22 AM EDT
Completed Phase 3 Interventional

S-Caine™ Peel (Skin Numbing Cream) to Treat Pain During Laser-Assisted Tattoo Removal in Adults

NCT00110734
View directory record Official record
Conditions
Pain
Interventions
S-Caine™ Peel (lidocaine and tetracaine cream 7%/7%)
Drug
Lead sponsor
ZARS Pharma Inc.
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2005
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 23, 2005 · Synced Oct 15, 2026, 3:22 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

AV-23-001 AVAVA MIRIA Pilot Study

NCT06557434
View directory record Official record
Conditions
Wrinkle, Acne Scars - Mixed Atrophic and Hypertrophic, Pigmented Lesions, Skin Laxity, Scars
Interventions
MIRIA
Device
Lead sponsor
AVAVA, Inc.
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
2
States / cities
Dix Hills, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 7, 2025 · Synced Oct 15, 2026, 3:22 AM EDT
Completed Not applicable Interventional Results available

A Device Study for the Treatment of Acne

NCT04695691
View directory record Official record
Conditions
Acne Vulgaris
Interventions
Cutera Laser System
Device
Lead sponsor
Cutera Inc.
Industry
Eligibility
16 Years to 60 Years
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
7
States / cities
Brisbane, California • Danville, California • Fremont, California + 4 more
Source: ClinicalTrials.gov public record
Updated Nov 2, 2023 · Synced Oct 15, 2026, 3:22 AM EDT