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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Leg Extension Exercise Clear all
Completed Not applicable Interventional

Pilot Study of the Effects of Exercise on Aging Among Older Persons With HIV

NCT01860261
View directory record Official record
Conditions
HIV
Interventions
Aerobic and Strength Training Intervention
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
50 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 7, 2023 · Synced Sep 3, 2026, 5:19 AM EDT
Completed Not applicable Interventional

A Study of the Effectiveness of Different Types of Exercise for People With Knee Osteoarthritis

NCT00519922
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Kinesthesia, Balance, and Agility (KBA) Exercise, Standard LE Strength Training
Other
Lead sponsor
The Arthritis Research Institute of America
Other
Eligibility
50 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Clearwater, Florida
Source: ClinicalTrials.gov public record
Updated Jul 21, 2008 · Synced Sep 3, 2026, 5:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving the Anabolic Action of Plant-based Foods Using Complementary Proteins

NCT06781723
View directory record Official record
Conditions
Health, Recreational Activities, Muscle Protein Synthetic Response to Protein, Muscle Protein Synthesis
Interventions
Resistance Exercise, Isolated Mixture, Rice and Beans
Behavioral · Dietary Supplement · Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
20 Years to 35 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated May 7, 2025 · Synced Sep 3, 2026, 5:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nighttime Macronutrient Choice and Combined Resistance and High-intensity Interval Training

NCT01830946
View directory record Official record
Conditions
Obesity
Interventions
Whey Protein, Combined Resistance and High-Intensity Interval training, Casein Protein
Other
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 45 Years
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Apr 14, 2013 · Synced Sep 3, 2026, 5:19 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Examining the Role of Female Endogenous Sex Hormones in Eccentric Exercise

NCT05934708
View directory record Official record
Conditions
Inflammatory Response
Interventions
Eccentric leg extension
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Sep 3, 2026, 5:19 AM EDT
Completed Not applicable Interventional

Appetite and Exercise in Breast Cancer Survivors

NCT04300478
View directory record Official record
Conditions
Overweight, Breast Cancer, Obesity
Interventions
REx Condition First, Sedentary Control Condition First
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Aurora, Colorado • Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 5, 2024 · Synced Sep 3, 2026, 5:19 AM EDT
Completed Not applicable Interventional

Comparison of Three Treatments for Lower Extremity Apophysitis

NCT01826071
View directory record Official record
Conditions
Osgood-Schlatter Syndrome (OSS), Sinding-Larson and Johansson Syndrome (SLJ), Sever's Disease, Apophysitis
Interventions
Static Stretch, Active Elongation
Other
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
8 Years to 17 Years
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 9, 2025 · Synced Sep 3, 2026, 5:19 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Immediate and 24-hour Effects of HyperVolt, Body Tempering, and Cupping Compared to Stretching on Hamstring Flexibility

NCT05793242
View directory record Official record
Conditions
Hamstring Contractures, Muscle Tightness
Interventions
Hypervolt, Body Tempering, Dry cupping, Static stretching
Device · Other
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years to 39 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced Sep 3, 2026, 5:19 AM EDT
Terminated Not applicable Interventional Results available

Yoga to Alleviate Fatigue, Anxiety and Pain in Adolescents During Treatment for Lymphoma or Leukemia

NCT02473523
View directory record Official record
Conditions
Leukemia, Hodgkin Lymphoma, Lymphoma, Non-Hodgkin's
Interventions
PedsQL Cancer Module, PedsQL Multidimensional Fatigue Scale, Biodex System 3 Dynamometer, Jamar Hydraulic Hand Dynamometer, Sit and Reach Test, Test of Motor Proficiency, Verbal Numeric Pain Scale, :Yoga Therapy
Other · Device
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
13 Years to 17 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 7, 2017 · Synced Sep 3, 2026, 5:19 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Effects of Open Chain Versus Closed Chain Strengthening on Dynamic Valgus During a Step Down Test

NCT06348836
View directory record Official record
Conditions
Dynamic Knee Valgus
Interventions
Exercise
Other
Lead sponsor
Alvernia University
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Reading, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 4, 2024 · Synced Sep 3, 2026, 5:19 AM EDT
Recruiting Not applicable Interventional

PREACTIVE: Preconditioning Exercise Intervention to Improve Symptoms and Quality of Life in Comorbid Atrial Fibrillation and HFpEF

NCT07324772
View directory record Official record
Conditions
Atrial Fibrillation (AF), Atrial Fibrillation (Paroxysmal), Persistent Atrial Fibrillation, Heart Failure With Preserved Ejection Fraction (HFPEF)
Interventions
progressive resistance training, combined aerobic + resistance training
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
60 Years to 99 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 23, 2026 · Synced Sep 3, 2026, 5:19 AM EDT
Recruiting Not applicable Interventional

RESISTance Exercise for Depression Trial

NCT06110897
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
High Dose Resistance Exercise Training, Low Dose Resistance Exercise Training Group
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 65 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
2
States / cities
Ames, Iowa • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 3, 2026, 5:19 AM EDT
Completed Not applicable Interventional

Resistance Training to Improve Fatigue and Physical Function in Postmenopausal Breast Cancer Survivors

NCT03539835
View directory record Official record
Conditions
Cancer
Interventions
Resistance training (RT), Cognitively-based compassion training control (CBCT)
Other · Behavioral
Lead sponsor
Emory University
Other
Eligibility
50 Years to 75 Years · Female only
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 26, 2020 · Synced Sep 3, 2026, 5:19 AM EDT
Completed Not applicable Interventional

Low-Load Blood Flow Restriction on Patients With Multiple Sclerosis

NCT05177952
View directory record Official record
Conditions
Training Study, Multiple Sclerosis, Blood Flow Restriction
Interventions
Blood Flow Restriction, Standard of Care
Other
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jun 10, 2024 · Synced Sep 3, 2026, 5:19 AM EDT
Completed Not applicable Interventional Results available

Anterior Cruciate Ligament Reconstruction and Plyometric Exercise

NCT01851655
View directory record Official record
Conditions
Anterior Cruciate Ligament Reconstruction
Interventions
Plyometric Exercise
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
15 Years to 30 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 17, 2014 · Synced Sep 3, 2026, 5:19 AM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

: Vascular Function in Health and Disease

NCT02966665
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease, Pulmonary Artery Hypertension, Heart Failure, Hypertension
Interventions
Maximum Exercise Tests, BH4, L-NMMA, Vitamin C, Vitamin E, α-Lipoic Acid and L-Ascorbate, BQ-123, Fexofenadine, Ranitidine, Angiotensin-II, Valsartan, Acetylcholine, Sodium Nitroprusside, Angiotensin-II, Norepinephrine, Phentolamine, BQ-123, MitoQ, BH4
Other · Drug
Lead sponsor
Russell Richardson
Other
Eligibility
18 Years and older
Enrollment
420 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2026
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Sep 25, 2025 · Synced Sep 3, 2026, 5:19 AM EDT
Completed Not applicable Interventional

Biopsychosocial Factors in Resistance Exercise in Individuals with Knee Pain

NCT06073899
View directory record Official record
Conditions
Knee Pain
Interventions
Leg Extension Exercise
Other
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 60 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Sep 25, 2024 · Synced Sep 3, 2026, 5:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Clinical Utility of Resistance Training for Improving Cardiovascular Disease Risk in Post-Menopausal Women

NCT03752060
View directory record Official record
Conditions
Cardiovascular Risk Factor, Menopause Related Conditions, Neuromuscular Function, Aerobic Capacity, Inflammation
Interventions
Resistance Exercise, Aerobic Exercise
Behavioral
Lead sponsor
Oklahoma State University
Other
Eligibility
45 Years to 65 Years · Female only
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Stillwater, Oklahoma
Source: ClinicalTrials.gov public record
Updated Mar 2, 2021 · Synced Sep 3, 2026, 5:19 AM EDT
Active, not recruiting Not applicable Interventional

Resistive Training Combined With Nutritional Therapy After Stroke

NCT02347995
View directory record Official record
Conditions
Stroke
Interventions
Protein, Placebo
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
30 Years to 85 Years
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Sep 3, 2026, 5:19 AM EDT
Completed Not applicable Interventional

Resistance Training in HFpEF

NCT02435667
View directory record Official record
Conditions
Heart Failure Preserved Ejection Fraction
Interventions
Resistance Exercise Training, DEXA bone scan, Cardiopulmonary Max Exercise Test, Quality of Life Questionnaire, Submaximal Exercise Test, Blood Draw
Other · Radiation
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 2, 2021 · Synced Sep 3, 2026, 5:19 AM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Muscle Function After Childbirth

NCT05073224
View directory record Official record
Conditions
Postpartum, Muscle Fatigue, Force Steadiness, Nulligravid, Muscle Weakness
Interventions
Active Straight Leg Raise Test, Active Straight Leg Raise Fatigue Task, Lower Extremity Strength Testing, Ultrasound imaging of abdominal wall
Diagnostic Test · Other
Lead sponsor
Carroll University
Other
Eligibility
20 Years to 35 Years · Female only
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Waukesha, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Sep 3, 2026, 5:19 AM EDT
Withdrawn Not applicable Interventional

Bilateral Versus Unilateral Strength Training After ACLR

NCT06032247
View directory record Official record
Conditions
Anterior Cruciate Ligament Injuries, Atrophy, Muscular, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
Interventions
Resistance exercise program- UL, Resistance exercise program- BL
Behavioral
Lead sponsor
University of Kansas
Other
Eligibility
18 Years to 35 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Oct 26, 2023 · Synced Sep 3, 2026, 5:19 AM EDT
Completed Not applicable Interventional

The Use of Neuromuscular Electrical Stimulation to Reverse Muscle Atrophy in Patients With Rheumatoid Arthritis

NCT00924625
View directory record Official record
Conditions
Rheumatoid Arthritis
Interventions
Neuromuscular electrical stimulation, Volitional exercises
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
21 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 9, 2014 · Synced Sep 3, 2026, 5:19 AM EDT
Not listed Not applicable Interventional

Evaluate Impact of Exercise Program on Fatigue in Breast Cancer During Chemotherapy

NCT05704842
View directory record Official record
Conditions
Breast Cancer
Interventions
Exercise
Behavioral
Lead sponsor
Virtua Health, Inc.
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Voorhees Township, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 4, 2024 · Synced Sep 3, 2026, 5:19 AM EDT