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Showing 1–24 of 600 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Leg exercise Clear all
Completed Not applicable Interventional

Impact of Exercise in Parkinson's Disease

NCT03495193
View directory record Official record
Conditions
Parkinson Disease
Interventions
Exercise training, Sleep hygiene
Other · Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
45 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 25, 2019 · Synced Sep 5, 2026, 4:24 PM EDT
Completed Phase 2 Interventional Results available

Polestriding Versus Walking for Subjects With Poor Leg Circulation

NCT00719355
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Walking with poles, Walking exercise
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
21 Years and older
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
1
States / cities
Hines, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 11, 2013 · Synced Sep 5, 2026, 4:24 PM EDT
Recruiting Not applicable Interventional

Postpartum Exercise Intervention

NCT07613333
View directory record Official record
Conditions
Postpartum, Neuromuscular Adaptations, Abdominal Muscles, Pelvic Floor Dysfunctions, Physical Activity
Interventions
Progressive exercise, Active Straight Leg Raise Test, Active Straight Leg Raise Fatigue Task, Lower Extremity Strength Testing, Ultrasound imaging of abdominal wall, Pelvic Floor Muscle Strength Testing, Pelvic Floor Muscle Endurance Testing
Other · Diagnostic Test
Lead sponsor
Carroll University
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Waukesha, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Sep 5, 2026, 4:24 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Leg Exercise Assistive Paddling (LEAP) Therapy for Peripheral Artery Disease

NCT06389149
View directory record Official record
Conditions
Peripheral Arterial Disease, Peripheral Vascular Disease, Peripheral Artery Occlusive Disease, Peripheral Artery Disease
Interventions
LEAP therapy, no LEAP therapy
Other
Lead sponsor
University of Nebraska
Other
Eligibility
55 Years to 85 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 5, 2026, 4:24 PM EDT
Completed Not applicable Interventional

Eccentric Exercise Versus Eccentric Exercise and Astym for Insertional Achilles Tendinopathy

NCT01988155
View directory record Official record
Conditions
Insertional Achilles Tendinopathy
Interventions
Eccentric Exercise, Astym
Other
Lead sponsor
Indiana University Health Ball Memorial Hospital Rehabiliation Services
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Muncie, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 22, 2016 · Synced Sep 5, 2026, 4:24 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Physical Activity in Adults With Amputation

NCT03722797
View directory record Official record
Conditions
Amputees
Interventions
Metabolic Cost Testing Procedures
Procedure
Lead sponsor
University of Delaware
Other
Eligibility
18 Years to 60 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Mar 3, 2022 · Synced Sep 5, 2026, 4:24 PM EDT
Terminated Not applicable Interventional Results available

Assessment of Pulmonary Congestion During Cardiac Hemodynamic Stress Testing

NCT04019613
View directory record Official record
Conditions
Dyspnea, Heart Failure With Preserved Ejection Fraction
Interventions
Lung ultrasound
Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 19, 2022 · Synced Sep 5, 2026, 4:24 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Two Time a Week vs. Five Time a Week Blood Flow Restriction Training Program for the Lower Extremity.

NCT05342909
View directory record Official record
Conditions
Blood Flow Restriction Training
Interventions
5x a week BFR training group, 2x a week BFR training group
Other
Lead sponsor
George Fox University
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
2
States / cities
Newberg, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 24, 2022 · Synced Sep 5, 2026, 4:24 PM EDT
Terminated Not applicable Interventional

Enhance Balance and Mobility in People With Type 2 Diabetic Peripheral Neuropathy

NCT02541838
View directory record Official record
Conditions
Diabetes Complications, Diabetic Neuropathies
Interventions
Muscle power, balance perturbation, aerobic exercise
Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
55 Years to 80 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 30, 2022 · Synced Sep 5, 2026, 4:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Medial Tibial Stress Syndrome Prevention

NCT07256808
View directory record Official record
Conditions
Medial Tibial Stress Syndrome
Interventions
Resistance Training
Other
Lead sponsor
Rowan University
Other
Eligibility
18 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Glassboro, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 30, 2025 · Synced Sep 5, 2026, 4:24 PM EDT
Recruiting Not applicable Interventional

PREACTIVE: Preconditioning Exercise Intervention to Improve Symptoms and Quality of Life in Comorbid Atrial Fibrillation and HFpEF

NCT07324772
View directory record Official record
Conditions
Atrial Fibrillation (AF), Atrial Fibrillation (Paroxysmal), Persistent Atrial Fibrillation, Heart Failure With Preserved Ejection Fraction (HFPEF)
Interventions
progressive resistance training, combined aerobic + resistance training
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
60 Years to 99 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 23, 2026 · Synced Sep 5, 2026, 4:24 PM EDT
Completed No phase listed Observational

Combined Strength Training and Functional Endurance Exercise Regimen on Cancer -Related Fatigue and Physical Performance

NCT00421057
View directory record Official record
Conditions
Breast Cancer, Fatigue
Interventions
Combined Strength Training and Functional Endurance Exercise, Questionnaire
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
21 Years to 60 Years · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 30, 2012 · Synced Sep 5, 2026, 4:24 PM EDT
Completed Not applicable Interventional

Effects of Contralateral Strength Training on Postoperative Strength Deficits in the Immobilized Lower Extremity

NCT03650374
View directory record Official record
Conditions
Meniscus; Detachment, Current Injury
Interventions
Standard of Care Rehabilitation, Experimental Strength Training
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Sep 5, 2026, 4:24 PM EDT
Recruiting Not applicable Interventional

Mental Imagery to Improve Quadriceps Strength Post Anterior Cruciate Ligament Reconstruction: a Feasibility Study

NCT06858293
View directory record Official record
Conditions
Anterior Cruciate Ligament Reconstruction
Interventions
Mental Imagery Open Chain, Mental Imagery Closed Chain
Behavioral
Lead sponsor
Marquette University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 9, 2025 · Synced Sep 5, 2026, 4:24 PM EDT
Not listed Not applicable Interventional

Home-Based Physical Activity Intervention for Taxane-Induced CIPN

NCT04621721
View directory record Official record
Conditions
Breast Cancer Female, Chemotherapy-induced Peripheral Neuropathy, Gait Disorders, Neurologic, Balance; Distorted, Muscle Weakness
Interventions
Gait/balance & resistive exercise
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
21 Years and older · Female only
Enrollment
312 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Nov 8, 2020 · Synced Sep 5, 2026, 4:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Exercise Effects on Word Learning

NCT03370471
View directory record Official record
Conditions
Aging, Aphasia
Interventions
Retrieval Practice + Moderate Intensity Exercise, Retrieval Practice + Gentle Stretching, Study Only + Moderate Intensity Exercise, Study Only + Gentle Stretching
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
35 Years to 89 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 4, 2021 · Synced Sep 5, 2026, 4:24 PM EDT
Active, not recruiting Not applicable Interventional

Progressive Rehabilitation Therapy in Patients With Advanced Lung Disease

NCT03562728
View directory record Official record
Conditions
Advanced Lung Disease, Lung Transplant, Extracorporeal Membrane Oxygenation
Interventions
MRP and NMES(neuromuscular electric stimulation), Standard of Care
Device · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 80 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 21, 2024 · Synced Sep 5, 2026, 4:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Physical Activity and Basal Metabolic Rate in Postmenopausal Women

NCT01550536
View directory record Official record
Conditions
Postmenopausal Metabolic Health
Interventions
Resistance and aerobic exercise
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
40 Years to 120 Years · Female only
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
3
States / cities
La Jolla, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 28, 2023 · Synced Sep 5, 2026, 4:24 PM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Study of Resting and Exercising Body Functioning in Freeman-Sheldon Syndrome and Related Conditions

NCT01306994
View directory record Official record
Conditions
Arthrogryposis, Craniofacial Abnormalities
Interventions
Lactate, Glucose, and Adenosine Triphosphate Blood Levels, Physiological Stress Test, Functional Enquiry Form, Strength, Joint ROM, Girth and Length Measurements, Study Physical Examination, Observational Gait Analysis, Mental Health Interview
Other · Procedure
Lead sponsor
Freeman-Sheldon Research Group, Inc.
Other
Eligibility
Not listed
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2022
U.S. locations
1
States / cities
Buckhannon, West Virginia
Source: ClinicalTrials.gov public record
Updated Jun 5, 2022 · Synced Sep 5, 2026, 4:24 PM EDT
Completed Not applicable Interventional Results available

Trial of Self-managed Approaches for Patellofemoral Pain Syndrome in Active Duty

NCT02597673
View directory record Official record
Conditions
Patellofemoral Pain Syndrome
Interventions
Home Exercise Program (HEP), NMES, TENS
Other · Device
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years to 45 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Fort Campbell North, Kentucky
Source: ClinicalTrials.gov public record
Updated Sep 30, 2020 · Synced Sep 5, 2026, 4:24 PM EDT
Recruiting Not applicable Interventional

Blood Flow Restriction for Optimizing Balance in Parkinson's Disease

NCT06508801
View directory record Official record
Conditions
Parkinson's Disease and Parkinsonism
Interventions
Blood flow restriction training, Instability Resistance Training
Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
40 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Sep 5, 2026, 4:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Functional and Self-reported Outcomes in Participants With a History of Musculoskeletal Knee Injury

NCT03617991
View directory record Official record
Conditions
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
Interventions
Exercise Group
Other
Lead sponsor
Johanna M. Hoch
Other
Eligibility
18 Years to 35 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated May 3, 2020 · Synced Sep 5, 2026, 4:24 PM EDT
Completed Not applicable Interventional Results available

Increasing Adherence to Pulmonary Rehabilitation After COPD Related Hospitalizations (Pilot Study)

NCT03865329
View directory record Official record
Conditions
COPD Exacerbation
Interventions
Intervention- Home-based Pulmonary Rehabilitation
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 9, 2020 · Synced Sep 5, 2026, 4:24 PM EDT
Completed Not applicable Interventional

Improving Functioning in Peripheral Arterial Disease

NCT00106327
View directory record Official record
Conditions
Cardiovascular Diseases, Peripheral Vascular Diseases
Interventions
Exercise, Diet
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
Not listed
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 24, 2012 · Synced Sep 5, 2026, 4:24 PM EDT