- Conditions
- Premature Lungs, Respiratory Distress Syndrome, Surfactant Deficiency Syndrome Neonatal
- Interventions
- Less Invasive Surfactant Administration LISA, Continuous Positive Airway Pressure CPAP
- Procedure
- Lead sponsor
- Sharp HealthCare
- Other
- Eligibility
- 24 Weeks to 29 Weeks
- Enrollment
- 180 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2025
- U.S. locations
- 3
- States / cities
- Irvine, California • Loma Linda, California • San Diego, California
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Showing 1–5
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- Conditions
- Respiratory Distress Syndrome (Neonatal), Surfactant Deficiency Syndrome Neonatal
- Interventions
- Video Laryngoscopy, Direct Laryngoscopy
- Procedure
- Lead sponsor
- University of Texas Southwestern Medical Center
- Other
- Eligibility
- 0 Hours to 3 Days
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Extreme Prematurity, Respiratory Distress Syndrome
- Interventions
- LISA
- Procedure
- Lead sponsor
- University of Texas Southwestern Medical Center
- Other
- Eligibility
- 5 Minutes to 20 Minutes
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2025
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Respiratory Distress Syndrome, Newborn
- Interventions
- IV Atropine and Fentanyl Premedication Arm, IV Normal Saline Placebo Arm
- Drug
- Lead sponsor
- University of Texas Southwestern Medical Center
- Other
- Eligibility
- 0 Hours to 72 Hours
- Enrollment
- 58 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Respiratory Distress Syndrome (RDS)
- Interventions
- LISA combination product (Curosurf+catheter CHF6440), Curosurf through conventional administration (endotracheal tube)
- Combination Product · Drug
- Lead sponsor
- Chiesi Farmaceutici S.p.A.
- Industry
- Eligibility
- 30 Minutes to 24 Hours
- Enrollment
- 33 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 26
- States / cities
- Little Rock, Arkansas • Los Angeles, California • Denver, Colorado + 22 more