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ClinicalTrials.gov public records Last synced Oct 7, 2026, 1:38 PM EDT

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Showing 1–24 of 261 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Letter Intervention Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluating a Preference-based Intervention for Increasing Colorectal Cancer Screening

NCT00810771
View directory record Official record
Conditions
Colorectal Neoplasms
Interventions
Standard Information, Preference-tailored Information
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
50 Years to 78 Years
Enrollment
466 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
2
States / cities
Ann Arbor, Michigan • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 2, 2015 · Synced Oct 7, 2026, 1:38 PM EDT
Completed Not applicable Interventional

CHOICES: Understanding Clinical Trials as a Treatment Option

NCT00983866
View directory record Official record
Conditions
Cancer
Interventions
Tailored Telephone Counseling
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
1,376 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2018
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated Jan 10, 2019 · Synced Oct 7, 2026, 1:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Positive Activities Intervention to Improve Quality of Life in Collectivist Culture Cancer Patients and Their Caregivers

NCT04810052
View directory record Official record
Conditions
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Interventions
Behavioral Intervention, Interview, Quality-of-Life Assessment, Questionnaire Administration
Behavioral · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Oct 7, 2026, 1:38 PM EDT
Active, not recruiting Not applicable Interventional

Impact of Patient-Centered Approach for Communicating Coronary Calcium on Cardiovascular Health

NCT06055972
View directory record Official record
Conditions
Coronary Artery Disease, Cardiovascular Diseases, Smoking
Interventions
Educational Letter Post CT Examination
Other
Lead sponsor
American College of Radiology
Other
Eligibility
50 Years to 80 Years
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Ann Arbor, Michigan • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 6, 2024 · Synced Oct 7, 2026, 1:38 PM EDT
Completed Not applicable Interventional

Improving Care of Osteoporosis: Multi-Modal Intervention to Increase Testing and Treatment (ICOMMIITT)

NCT00788632
View directory record Official record
Conditions
Osteoporosis
Interventions
Patient educational DVD and brochure, Physician web modules, System
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
65 Years and older · Female only
Enrollment
12,128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
2
States / cities
Atlanta, Georgia • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 22, 2013 · Synced Oct 7, 2026, 1:38 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Scalable Interventions to Increase PrEP Adherence: Value Affirmation and Future Selves

NCT03278990
View directory record Official record
Conditions
HIV Prevention
Interventions
Value Affirmation and Future Selves Combination, Control writing exercise
Behavioral
Lead sponsor
Stuart Fisk
Other
Eligibility
18 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 11, 2021 · Synced Oct 7, 2026, 1:38 PM EDT
Completed Not applicable Interventional

Nudging Flu Vaccination in Patients at Moderately High Risk for Flu and Flu-related Complications

NCT05509283
View directory record Official record
Conditions
Influenza, Vaccination, Health Promotion, Health Behavior, Risk Reduction
Interventions
Risk Reduction
Behavioral
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years and older
Enrollment
40,671 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 5, 2022 · Synced Oct 7, 2026, 1:38 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Initial Testing of a Behavioral Intervention About Genetic Services for Families at Risk of Lynch Syndrome

NCT07106359
View directory record Official record
Conditions
Cascade Testing, Lynch Syndrome, Decision Making, Colorectal Cancer, Uterine Cancer, Cancer Prevention
Interventions
Information Letter and Booklet, Information Letter
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
185 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 7, 2026, 1:38 PM EDT
Active, not recruiting Not applicable Interventional

A Pragmatic Trial of Chronic Disease Approaches to Ameliorate Tobacco Related Cardiovascular Disease Health Disparities

NCT05671380
View directory record Official record
Conditions
Tobacco Use Cessation, Cardiovascular Diseases, Tobacco Use, Smoking, Smoking Cessation
Interventions
Longitudinal Proactive Outreach (LPO)., Ask-Advice-Connect (AAC)
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
3
States / cities
Minneapolis, Minnesota • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 7, 2026, 1:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Patient Activation After DXA Result Notification

NCT01507662
View directory record Official record
Conditions
Osteoporosis, Bone Diseases, Metabolic
Interventions
Bone Mineral Density Result Letter and Bone Health Brochure
Behavioral
Lead sponsor
Fredric D Wolinsky
Other
Eligibility
50 Years and older
Enrollment
7,749 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
3
States / cities
Birmingham, Alabama • Atlanta, Georgia • Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Nov 10, 2020 · Synced Oct 7, 2026, 1:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Breathe for Hot Flashes Randomized Controlled Trial

NCT00819182
View directory record Official record
Conditions
Hot Flashes
Interventions
Paced respiration, Sham comparator: fast shallow breathing
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older · Female only
Enrollment
218 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 24, 2016 · Synced Oct 7, 2026, 1:38 PM EDT
Terminated Not applicable Interventional Results available

Memory Training in Aneurysmal Subarachnoid Hemorrhage Patients

NCT02864940
View directory record Official record
Conditions
Ruptured Aneurysm, Memory Deficits, Subarachnoid Hemorrhage
Interventions
Lumosity, Crossword puzzle
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 10, 2023 · Synced Oct 7, 2026, 1:38 PM EDT
Completed Not applicable Interventional

Using Personalized Letters and Emails to Increase Health Insurance Take-up and Improve Plan Choice Quality

NCT05216458
View directory record Official record
Conditions
Health Behavior
Interventions
Emails and letter intervention, Control group
Behavioral
Lead sponsor
Office of Evaluation Sciences
Federal
Eligibility
Not listed
Enrollment
44,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jan 31, 2022 · Synced Oct 7, 2026, 1:38 PM EDT
Recruiting No phase listed Observational

Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants

NCT05589714
View directory record Official record
Conditions
Inherited Retinal Degeneration, Retinitis Pigmentosa
Interventions
Not listed
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
4 Years and older
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
19
States / cities
Little Rock, Arkansas • Los Angeles, California • San Francisco, California + 16 more
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Oct 7, 2026, 1:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Usefulness of Video-Based Intervention in Helping Participants Encourage Their Families to Get Tested for BRCA Gene Mutations

NCT05264532
View directory record Official record
Conditions
BRCA1 Gene Mutation, BRCA2 Gene Mutation
Interventions
Informational Intervention, Survey Administration
Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years to 80 Years
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2025
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Oct 7, 2026, 1:38 PM EDT
Withdrawn Not applicable Interventional

Cardiology Prevention in Systemic Lupus Erythematosus (SLE)

NCT00610805
View directory record Official record
Conditions
Systemic Lupus Erythematosus
Interventions
Preventive Cardiology, Usual Care
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
19 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 15, 2016 · Synced Oct 7, 2026, 1:38 PM EDT
Completed Not applicable Interventional

Feasibility of Telephone Counseling to Increase Physical Fitness in SCI

NCT02225028
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Physical Activity Counseling
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
2
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 5, 2017 · Synced Oct 7, 2026, 1:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Study Comparing Two Versions of Group Cognitive-behavioral Indicated Prevention Programs

NCT04111887
View directory record Official record
Conditions
Depressive Symptoms
Interventions
Group-based therapy
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
18 Years to 28 Years
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 16, 2020 · Synced Oct 7, 2026, 1:38 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Optimizing Antibiotics Prescription

NCT06436690
View directory record Official record
Conditions
Antimicrobial Resistance
Interventions
Diagnosis Mandate, Individualized Feedback
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 7, 2026, 1:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mammogram Mail- and Phone-based Interventions

NCT05853848
View directory record Official record
Conditions
Breast Cancer
Interventions
Postcard, Letter, Auto-dialer, Live call
Behavioral
Lead sponsor
Geisinger Clinic
Other
Eligibility
51 Years to 74 Years · Female only
Enrollment
14,386 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 10, 2024 · Synced Oct 7, 2026, 1:38 PM EDT
Recruiting Not applicable Interventional

Re-Engaging AYA Survivors in Cancer-Related Healthcare

NCT07138040
View directory record Official record
Conditions
Cancer
Interventions
Stage 1 Written Information, Stage 1 Low Touch Intervention, Stage 2 Written Information, Stage 2 Low Touch Intervention, Stage 2 High Touch Intervention
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
15 Years to 29 Years
Enrollment
530 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
3
States / cities
Columbus, Ohio • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Oct 7, 2026, 1:38 PM EDT
Completed Not applicable Interventional

Default Bulk Ordering and Text Messaging to Enhance Outreach for Lipid Screening (Missing Lipids)

NCT05724615
View directory record Official record
Conditions
Atherosclerotic Cardiovascular Disease
Interventions
Outreach + Bulk ordering, Outreach + Bulk ordering + Text Based Reminders and Scheduling assistance
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
20 Years to 75 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 5, 2024 · Synced Oct 7, 2026, 1:38 PM EDT
Completed Not applicable Interventional

Effect of Mailed Invites of Choice of Colonoscopy or FIT vs. Mailed FIT Alone on Colorectal Cancer Screening

NCT03414125
View directory record Official record
Conditions
Colorectal Cancer
Interventions
FIT Screening Strategy, Choice Screening Strategy
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
50 Years to 63 Years
Enrollment
26,859 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 13, 2021 · Synced Oct 7, 2026, 1:38 PM EDT
Completed Not applicable Interventional

Collaborative Care for Infants at Risk

NCT03199326
View directory record Official record
Conditions
Child Abuse, Primary Health Care, Child Welfare
Interventions
Collaborative Care
Other
Lead sponsor
University of Utah
Other
Eligibility
0 Days to 364 Days
Enrollment
468 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 10, 2020 · Synced Oct 7, 2026, 1:38 PM EDT