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ClinicalTrials.gov public records Last synced Oct 7, 2026, 10:37 AM EDT

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Showing 49–72 of 388 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Lifestyle Weight Loss Intervention Clear all
Recruiting Phase 2 Interventional

Phentermine's Impact on Treatment in Teens

NCT07282340
View directory record Official record
Conditions
Childhood Obesity
Interventions
Phentermine, Placebo
Drug
Lead sponsor
Russell McCulloh, MD
Network
Eligibility
12 Years to 17 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
8
States / cities
Wilmington, Delaware • Louisville, Kentucky • Baton Rouge, Louisiana + 5 more
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 7, 2026, 10:37 AM EDT
Recruiting Not applicable Interventional

Feasibility of a Nutrition Intervention for Patients With Prediabetes at a Federally Qualified Health Center

NCT06897982
View directory record Official record
Conditions
Prediabetic State, PreDiabetes, Health Knowledge, Attitudes, Practice, Nutrition, Healthy, Acceptability of Health Care, Obesity Prevention
Interventions
One-arm feasibility pilot of a nutrition intervention to recruit, engage, and retain DPP participants in the safety-net setting in Los Angeles
Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 99 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 7, 2026, 10:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Efficacy of Two Novel Behavioral Post-cessation Weight Gain Interventions

NCT03156660
View directory record Official record
Conditions
Weight Change, Body, Smoking Cessation
Interventions
Weight gain prevention (Group 1), Weight loss intervention (Group 2), Self-guided intervention (Group 3)
Behavioral
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Enrollment
305 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 21, 2023 · Synced Oct 7, 2026, 10:37 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Impact of Group Size in Weight Loss Interventions

NCT01165151
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
behavioral weight loss program
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
21 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Mar 6, 2015 · Synced Oct 7, 2026, 10:37 AM EDT
Completed Not applicable Interventional

Lifestyle Intervention to Improve Bone Quality

NCT03329963
View directory record Official record
Conditions
Aging, Obesity
Interventions
Healthy Lifestyle Intervention, Lifestyle Intervention
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
65 Years to 85 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 6, 2025 · Synced Oct 7, 2026, 10:37 AM EDT
Completed Not applicable Interventional Results available

Promoting Successful Weight Loss in Primary Care in Louisiana

NCT02561221
View directory record Official record
Conditions
Obesity
Interventions
Lifestyle Counseling
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
20 Years to 75 Years
Enrollment
803 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Aug 1, 2023 · Synced Oct 7, 2026, 10:37 AM EDT
Completed Not applicable Interventional Results available

Pragmatic Obstructive Sleep Apnea Weight Loss Trial Assessing Effectiveness and Reach

NCT05104450
View directory record Official record
Conditions
Obesity, Sleep Apnea, Obstructive
Interventions
lifestyle intervention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
696 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 12, 2026 · Synced Oct 7, 2026, 10:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Sleep Goal-focused Online Access to Lifestyle Support

NCT05942326
View directory record Official record
Conditions
Weight Loss, Weight, Body
Interventions
Sleep GOALS, Education
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Oct 7, 2026, 10:37 AM EDT
Active, not recruiting Not applicable Interventional

Weight Loss and Endocrine Disrupting Chemicals (EDCs): Lifestyle Interventions to Lose Weight and Reduce EDC Exposure in Individuals With Overweight/Obesity

NCT07560579
View directory record Official record
Conditions
Obesity &Amp;Amp;Amp; Overweight, Environmental Exposure, Overweight (BMI > 25)
Interventions
Educational curriculum, Weight loss Application, Urinary EDC metabolite testing, Siphox clinic biomarker test, Weight loss reporting
Behavioral · Diagnostic Test
Lead sponsor
Million Marker Wellness, Inc.
Industry
Eligibility
18 Years and older
Enrollment
226 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 7, 2026, 10:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Maintenance-Tailored Obesity Treatment

NCT00670462
View directory record Official record
Conditions
Obesity
Interventions
Standard Behavioral Treatment (SBT), Maintenance-Tailored Treatment (MTT)
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
213 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2010
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 22, 2017 · Synced Oct 7, 2026, 10:37 AM EDT
Completed Phase 4 Interventional Results available

Semaglutide Treatment, Appetite, and Eating Behavior: Long-term Effects

NCT05548647
View directory record Official record
Conditions
Obesity
Interventions
Behavioral Treatment, Placebo, Semaglutide 2.4 MG/0.75 ML Subcutaneous Solution [WEGOVY]
Behavioral · Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 70 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 7, 2026, 10:37 AM EDT
Recruiting Phase 2 Interventional

Pharmacologic Weight Loss as Adjunct Therapy for Ulcerative Colitis in Obese Patients

NCT04721873
View directory record Official record
Conditions
Colitis, Ulcerative, Obesity
Interventions
Phentermine-Topiramate, Placebo
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated May 16, 2023 · Synced Oct 7, 2026, 10:37 AM EDT
Withdrawn Not applicable Interventional

Community-based CBT and T2D in Latino Population

NCT05222373
View directory record Official record
Conditions
Type 2 Diabetes, Mental Health Issue, Quality of Life, Weight Loss
Interventions
CBT-based lifestyle intervention
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
35 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated Jul 10, 2025 · Synced Oct 7, 2026, 10:37 AM EDT
Completed Not applicable Interventional

Physical Activity Choices Everyday- A Pilot Study

NCT03843099
View directory record Official record
Conditions
Obesity
Interventions
Behavioral Weight Loss + Future Thinking, Behavioral Weight Loss + Healthy Thinking
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 70 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 4, 2019 · Synced Oct 7, 2026, 10:37 AM EDT
Completed Phase 3 Interventional

Lifestyle, Exercise and Nutrition Study 1

NCT02109068
View directory record Official record
Conditions
Breast Cancer, Weight Loss
Interventions
Weight Loss Counseling- Phone, Weight Loss Counseling- In-Person
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 9, 2014 · Synced Oct 7, 2026, 10:37 AM EDT
Active, not recruiting Phase 3 Interventional

Breast Cancer WEight Loss Study (BWEL Study)

NCT02750826
View directory record Official record
Conditions
Breast Ductal Carcinoma In Situ, Invasive Breast Carcinoma, Stage II Breast Cancer AJCC v6 and v7, Stage IIB Breast Cancer AJCC v6 and v7, Stage IIIA Breast Cancer AJCC v7, Stage IIIC Breast Cancer AJCC v7, Synchronous Bilateral Breast Carcinoma
Interventions
Health Education Program, Weight Loss Intervention
Other
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
18 Years and older · Female only
Enrollment
3,177 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2030
U.S. locations
1464
States / cities
Daphne, Alabama • Mobile, Alabama • Anchorage, Alaska + 921 more
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 7, 2026, 10:37 AM EDT
Completed Not applicable Interventional

Lifestyle Intervention Program for Women With Gestational Diabetes or Gestational Impaired Glucose Tolerance

NCT01489163
View directory record Official record
Conditions
Gestational Diabetes
Interventions
Lifestyle Counseling
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
20 Years to 45 Years · Female only
Enrollment
352 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated Feb 4, 2019 · Synced Oct 7, 2026, 10:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Parents and Children Together Preventing Diabetes (PACT PD)

NCT01819493
View directory record Official record
Conditions
Diabetes Prevention
Interventions
Lifestyle Intervention, Standard Family-Based intervention
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
8 Years and older
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 15, 2018 · Synced Oct 7, 2026, 10:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Pharmacist-Coordinated Implementation of the Diabetes Prevention Program

NCT02384109
View directory record Official record
Conditions
Prediabetic State
Interventions
Shared decision-making with pharmacists, Standard care from primary care providers
Behavioral · Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
521 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
20
States / cities
Burbank, California • Los Angeles, California • Pacific Palisades, California + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 27, 2019 · Synced Oct 7, 2026, 10:37 AM EDT
Completed Not applicable Interventional

Pathobiology and Reversibility of Prediabetes in a Biracial Cohort

NCT02027571
View directory record Official record
Conditions
Prediabetes, Type 2 Diabetes, Obesity
Interventions
Intensive Lifestyle Intervention (ILI)
Behavioral
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years to 65 Years
Enrollment
223 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 15, 2018 · Synced Oct 7, 2026, 10:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mediterranean Diet and Weight Loss: Targeting the Bile Acid/Gut Microbiome Axis to Reduce Colorectal Cancer

NCT04753359
View directory record Official record
Conditions
Colorectal Cancer, Diet Habit
Interventions
Med, WL
Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
45 Years to 75 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Oct 7, 2026, 10:37 AM EDT
Completed Not applicable Interventional

Lifestyle Intervention for Treatment of Diabetes

NCT01806727
View directory record Official record
Conditions
Type 2 Diabetes, Overweight, Obesity
Interventions
Community Lifestyle Weight Loss (LWL), Diabetes Self Management (DSM)
Behavioral
Lead sponsor
Wake Forest University
Other
Eligibility
21 Years and older
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 15, 2018 · Synced Oct 7, 2026, 10:37 AM EDT
Completed Not applicable Interventional

Valued EpiGenetic Glycemic ImprovEments Through Weight Loss

NCT02869659
View directory record Official record
Conditions
Obesity, Pre-diabetes
Interventions
Weight Loss Group, Delayed Weight Loss
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
40 Years to 65 Years
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 31, 2020 · Synced Oct 7, 2026, 10:37 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Vivamos Activos Fair Oaks Program for Weight Loss in Low Income Latinos

NCT01242683
View directory record Official record
Conditions
Obesity
Interventions
Vivamos Activos Fair Oaks Program
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
207 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
4
States / cities
Palo Alto, California • Redwood City, California • San Mateo, California + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 2, 2014 · Synced Oct 7, 2026, 10:37 AM EDT