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ClinicalTrials.gov public records Last synced Oct 25, 2026, 1:22 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1249–1272 of 1,504 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Local ablative therapy Clear all
Recruiting No phase listed Observational

Intra-procedural Spectral CT for Image-guided Embolization and Ablation in Interventional Oncology

NCT07303725
View directory record Official record
Conditions
Liver Cancer (Primary and Metastatic), Renal Cancer
Interventions
Not listed
Lead sponsor
Palo Alto Veterans Institute for Research
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Dec 26, 2025 · Synced Oct 25, 2026, 1:22 AM EDT
Completed Phase 4 Interventional Results available

Metformin as an Adjunctive Therapy to Catheter Ablation in Atrial Fibrillation

NCT04625946
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Metformin, Recommendations for lifestyle modification., AliveCor
Drug · Behavioral · Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 25, 2026, 1:22 AM EDT
Withdrawn Phase 4 Interventional

Comparison of Reverse Remodeling and PVI Versus CFAE and/or Linear Lesions and PVI for Persistent AF

NCT01877473
View directory record Official record
Conditions
Persistent Atrial Fibrillation
Interventions
Ablation
Procedure
Lead sponsor
Valley Health System
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Ridgewood, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 17, 2014 · Synced Oct 25, 2026, 1:22 AM EDT
Not listed No phase listed Observational

MyLeukoMAP™ Genomic Survival Prediction Assay Pivotal Clinical Study

NCT05258942
View directory record Official record
Conditions
Heart Failure
Interventions
Observational
Other
Lead sponsor
LeukoLifeDx Inc
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Timeline
2022 – 2023
U.S. locations
3
States / cities
New Haven, Connecticut • Orlando, Florida • Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 27, 2022 · Synced Oct 25, 2026, 1:22 AM EDT
Completed Phase 2 Interventional Results available

Chemotherapy, Radiation Therapy, and Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer

NCT00003270
View directory record Official record
Conditions
Graft Versus Host Disease, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes
Interventions
anti-thymocyte globulin, filgrastim, busulfan, cyclophosphamide, cyclosporine, methylprednisolone, bone marrow ablation with stem cell support, umbilical cord blood transplantation, radiation therapy
Biological · Drug · Procedure + 1 more
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
5 Years to 50 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2017
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Dec 13, 2019 · Synced Oct 25, 2026, 1:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Non-Ablative Laser for Treatment of Direct Brow Lift Scars

NCT02032641
View directory record Official record
Conditions
Scar
Interventions
Laser treatment
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
2
States / cities
Miami, Florida • Plantation, Florida
Source: ClinicalTrials.gov public record
Updated Jan 27, 2017 · Synced Oct 25, 2026, 1:22 AM EDT
Completed Phase 4 Interventional

Effect of Preoperative Pupil Size on Quality of Vision After Wavefront-Guided LASIK

NCT00889941
View directory record Official record
Conditions
Myopia
Interventions
LASIK
Procedure
Lead sponsor
Stanford University
Other
Eligibility
Not listed
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Apr 29, 2009 · Synced Oct 25, 2026, 1:22 AM EDT
Not listed No phase listed Observational

Persistent Atrial Fibrillation Cryoballoon Ablation

NCT02166723
View directory record Official record
Conditions
Persistent Atrial Fibrillation
Interventions
cryoballoon ablation
Device
Lead sponsor
Staten Island University Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 18, 2014 · Synced Oct 25, 2026, 1:22 AM EDT
Completed Phase 3 Interventional

Impact Of Different Ablation Approaches on Outcome In Coexistent Atrial Fibrillation and Flutter

NCT01439386
View directory record Official record
Conditions
Atrial Arrhythmia, Quality of Life
Interventions
Catheter ablation
Procedure
Lead sponsor
Texas Cardiac Arrhythmia Research Foundation
Other
Eligibility
18 Years to 75 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Oct 19, 2017 · Synced Oct 25, 2026, 1:22 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Intraosseous Basivertebral Nerve Ablation for Treatment of Chronic Low Back Pain

NCT03658018
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Intracept System Ablation
Device
Lead sponsor
Relievant Medsystems, Inc.
Industry
Eligibility
25 Years to 70 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Plano, Texas
Source: ClinicalTrials.gov public record
Updated Aug 15, 2019 · Synced Oct 25, 2026, 1:22 AM EDT
Completed Phase 3 Interventional Results available

Treatment for CI-DME in Eyes With Very Good VA Study

NCT01909791
View directory record Official record
Conditions
Diabetic Macular Edema
Interventions
Prompt Laser, Prompt aflibercept, Deferred laser, Deferred aflibercept
Procedure · Drug
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
18 Years and older
Enrollment
702 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
100
States / cities
Phoenix, Arizona • Tucson, Arizona • Little Rock, Arkansas + 84 more
Source: ClinicalTrials.gov public record
Updated Jul 31, 2020 · Synced Oct 25, 2026, 1:22 AM EDT
Completed Not applicable Interventional

LS-PersAFone: Pulsed Field Ablation for Long-Standing Persistent Atrial Fibrillation

NCT06128174
View directory record Official record
Conditions
Long-standing Persistent AF
Interventions
Farawave PFA catheter
Device
Lead sponsor
Vivek Reddy
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Oct 25, 2026, 1:22 AM EDT
Terminated No phase listed Observational

Patient Specific Optimized Therapy Post-Market Clinical Follow-up Study

NCT03481413
View directory record Official record
Conditions
Arrythmia
Interventions
Ablation
Device
Lead sponsor
EPD Solutions, A Philips Company
Industry
Eligibility
18 Years and older
Enrollment
566 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
6
States / cities
Sacramento, California • Chicago, Illinois • Baltimore, Maryland + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 8, 2023 · Synced Oct 25, 2026, 1:22 AM EDT
Completed Not applicable Interventional Results available

Safety Study of ExAblate for the Treatment of Uterine Fibroids

NCT01142791
View directory record Official record
Conditions
Uterine Fibroids
Interventions
ExAblate
Device
Lead sponsor
InSightec
Industry
Eligibility
18 Years and older · Female only
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
8
States / cities
Los Angeles, California • San Diego, California • San Francisco, California + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 19, 2019 · Synced Oct 25, 2026, 1:22 AM EDT
Completed Not applicable Interventional Results available

Fractional Laser Assisted Steroid Therapy vs Intralesional Steroids in the Treatment of Keloids

NCT02996097
View directory record Official record
Conditions
Keloid
Interventions
The Lutronic electronic carbon dioxide (eCO2) Plus laser system, Intralesional Triamcinolone Acetonide
Device · Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 17, 2020 · Synced Oct 25, 2026, 1:22 AM EDT
Completed Early Phase 1 Interventional

Focal Laser Ablation of Prostate Cancer

NCT04305925
View directory record Official record
Conditions
Prostate Cancer
Interventions
Focal Laser Ablation
Device
Lead sponsor
Jonsson Comprehensive Cancer Center
Other
Eligibility
40 Years to 85 Years · Male only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 24, 2026 · Synced Oct 25, 2026, 1:22 AM EDT
Completed No phase listed Observational

American Breast Laser Ablation Therapy Evaluation

NCT00807924
View directory record Official record
Conditions
Benign Breast Conditions; Breast Fibroadenomas
Interventions
Not listed
Lead sponsor
Novian Health Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 4, 2023 · Synced Oct 25, 2026, 1:22 AM EDT
Completed Phase 2Phase 3 Interventional Results available

A Clinical Trial Utilizing Dantrolene in Patients With Ventricular Arrhythmias.

NCT04134845
View directory record Official record
Conditions
Ventricular Tachycardia
Interventions
Dantrolene/Ryanodex, Placebo
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 25, 2026, 1:22 AM EDT
Active, not recruiting Phase 3 Interventional

A Pivotal Study of Safety and Effectiveness of NanoKnife IRE for Stage 3 Pancreatic Cancer

NCT03899636
View directory record Official record
Conditions
Stage III Pancreatic Cancer
Interventions
Modified FOLFIRINOX Regimen, NanoKnife System
Drug · Device
Lead sponsor
Angiodynamics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
528 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
6
States / cities
Miami, Florida • Tampa, Florida • Arlington Heights, Illinois + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 12, 2025 · Synced Oct 25, 2026, 1:22 AM EDT
Recruiting No phase listed Observational

Clinical Evaluation of WaveLight Plus LASIK

NCT07127757
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Wavelight Plus LASIK
Device
Lead sponsor
Laser Defined Vision
Other
Eligibility
18 Years and older
Enrollment
50 participants
Timeline
2025 – 2026
U.S. locations
1
States / cities
Greensboro, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Oct 25, 2026, 1:22 AM EDT
Completed Not applicable Interventional

Randomized Study of Photodynamic Therapy Using Dihematoporphyrin in Patients With Corneal Neovascularization

NCT00004430
View directory record Official record
Conditions
Corneal Neovascularization
Interventions
Dihematoporphyrin derivative, prednisolone, Laser surgery
Drug · Procedure
Lead sponsor
Medical College of Hampton Roads
Other
Eligibility
12 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1994 – 1998
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 25, 2015 · Synced Oct 25, 2026, 1:22 AM EDT
Recruiting Not applicable Interventional

Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having HFpEF

NCT04592445
View directory record Official record
Conditions
Heart Failure With Preserved Ejection Fraction (HFpEF
Interventions
Greater Splanchnic Nerve Ablation, Sham Control
Device
Lead sponsor
Axon Therapies, Inc.
Industry
Eligibility
40 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2029
U.S. locations
24
States / cities
Birmingham, Alabama • Phoenix, Arizona • La Jolla, California + 17 more
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 25, 2026, 1:22 AM EDT
Completed Not applicable Interventional

The Physiological Effects of Pacing on Catheter Ablation Procedures to Treat Atrial Fibrillation

NCT02766712
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Pace During 1st Half of Lesion, Pace During 2nd Half of Lesion
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 12, 2019 · Synced Oct 25, 2026, 1:22 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Image Guided Targeted Photoablation for the Treatment of Localized Hyperhidrosis

NCT04178161
View directory record Official record
Conditions
Hyperhidrosis
Interventions
Laser treatment
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 26, 2026 · Synced Oct 25, 2026, 1:22 AM EDT