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ClinicalTrials.gov public records Last synced Nov 14, 2026, 5:49 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–11 of 11 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Lorcaserin, 20 mg Clear all

Conditions: Obesity
Interventions: lorcaserin hydrochloride XR, Placebo; Drug
Lead sponsor: Eisai Inc.; Industry
Eligibility: 12 Years to 17 Years
Enrollment: 278 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2020
U.S. locations: 16
States / cities: Phoenix, Arizona • Bell Gardens, California • Long Beach, California + 13 more

Conditions: Cocaine Use Disorder
Interventions: Lorcaserin, Cocaine Intravenous (IV), Placebo comparator; Drug
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years to 59 Years
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Cardiovascular Diseases
Interventions: Ziprasidone, Lorcaserin, Placebo Oral Tablet; Drug
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Obesity
Interventions: Not listed
Lead sponsor: Currax Pharmaceuticals; Industry
Eligibility: 18 Years and older
Enrollment: 31,889 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2022
U.S. locations: 1
States / cities: Brentwood, Tennessee

Conditions: Schizophrenia, Schizoaffective Disorder, Overweight
Interventions: Lorcaserin, Metformin, Placebo; Drug
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 65 Years
Enrollment: 71 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 4
States / cities: Augusta, Georgia • New York, New York • Chapel Hill, North Carolina + 1 more

Conditions: Healthy Participants
Interventions: Lorcaserin manufactured at Zofingen, Lorcaserin manufactured at Kawashima; Drug
Lead sponsor: Eisai Inc.; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Cocaine Use Disorders
Interventions: Lorcaserin, 10 mg, Lorcaserin, 20 mg, Oral Placebo; Drug · Other
Lead sponsor: Midwest Biomedical Research; Other
Eligibility: 21 Years to 50 Years
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Kansas City, Missouri

Conditions: Cocaine Use Disorder
Interventions: lorcaserin, Placebo Oral Tablet, Substance use counseling, ACASI, Cocaine metabolites, Ecological Momentary Assessment (EMA), Balloon Analogue Risk Task (BART), Qualitative Exit Interview; Drug · Behavioral · Diagnostic Test
Lead sponsor: Glenn-Milo Santos; Other
Eligibility: 18 Years to 65 Years · Male only
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Cocaine-Related Disorders, Opioid-Related Disorders
Interventions: Group A Lorcaserin (10mg), Group A2 Lorcaserin (20 mg), Group B Parallel Placebo, Group B2 Parallel Placebo; Drug · Other
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years to 55 Years
Enrollment: 171 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Cocaine Abuse
Interventions: Lorcaserin, Placebo, Cocaine Infusion; Drug
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 50 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015
U.S. locations: 1
States / cities: Overland Park, Kansas

Conditions: Epilepsies, Myoclonic
Interventions: Placebo, Lorcaserin; Drug
Lead sponsor: Eisai Inc.; Industry
Eligibility: 2 Years and older
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 25
States / cities: Birmingham, Alabama • Los Angeles, California • San Diego, California + 20 more

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Study to Evaluate the Efficacy and Safety of Belviq XR® in Conjunction With Lifestyle Modification for Weight Loss in Obese Adolescents, Age 12 to 17 Years

Drug Interaction and Self Administration Studies of Compounds for Cocaine Use Disorder

Gene-by-Stress Interactions in Intervention Studies Significance

Real-World Evidence on the Cardiovascular Safety of CONTRAVE® in the United States (U.S.)

MEtformin and Lorcaserin for WeighT Loss in Schizophrenia

A Study to Demonstrate Bioequivalence Between Lorcaserin Extended Release (XR) Tablets Manufactured in Kawashima and Lorcaserin XR Tablets Manufactured in Zofingen in Healthy Participants

Lorcaserin Intra Venous Cocaine Effects

Treatment With Lorcaserin for Cocaine Use: The TLC Study

Phase I Functional Magnetic Resonance Imaging (fMRI) Pharmacodynamic Studies of Compounds for Opioid Use Disorder and Cocaine Use Disorder

Study to Assess Potential Interactions Between Intravenous Cocaine and Oral Lorcaserin

A Study of Lorcaserin as Adjunctive Treatment in Participants With Dravet Syndrome