- Conditions
- Blood Pressure, Inflammation
- Interventions
- Recommended sodium and low fructose diet, High sodium and low fructose diet, High sodium and high fructose diet
- Dietary Supplement
- Lead sponsor
- University of Delaware
- Other
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 91 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- Newark, Delaware
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Showing 1–24
of 26
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Hyperuricemia
- Interventions
- low-fructose diet, Allopurinol
- Other · Drug
- Lead sponsor
- University of Missouri-Columbia
- Other
- Eligibility
- 40 Years to 70 Years
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2019
- U.S. locations
- 1
- States / cities
- Columbia, Missouri
- Conditions
- Irritable Bowel Syndrome With Diarrhea, Irritable Bowel Syndrome With Mixed Bowel Habits
- Interventions
- Dietary Intervention
- Other
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2023
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Obesity
- Interventions
- VI-0521, Placebo matched phentermine/topiramate
- Drug
- Lead sponsor
- VIVUS LLC
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 1,267 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2009
- U.S. locations
- 5
- States / cities
- San Diego, California • Ridgefield, Connecticut • Durham, North Carolina + 2 more
- Conditions
- Alcohol Dependence, Nicotine Dependence
- Interventions
- Low-Dose Topiramate, Placebo, High-Dose Topiramate
- Drug
- Lead sponsor
- University of Virginia
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 236 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2017
- U.S. locations
- 4
- States / cities
- La Jolla, California • Houston, Texas • Charlottesville, Virginia + 1 more
- Conditions
- Cardiovascular Risk Factors
- Interventions
- Alternative Snack Comparator, Raisins
- Other
- Lead sponsor
- Louisville Metabolic and Atherosclerosis Research Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 49 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010 – 2011
- U.S. locations
- 1
- States / cities
- Louisville, Kentucky
- Conditions
- Diabetes Mellitus, Type 2, Cystic Fibrosis
- Interventions
- Oral Glucose Tolerance Test, High Glycemic Index Meal, Low Glycemic Index Meal, Test Soda, Fruit juice
- Other
- Lead sponsor
- Emory University
- Other
- Eligibility
- 1 Year and older
- Enrollment
- 34 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2018
- U.S. locations
- 1
- States / cities
- Atlanta, Georgia
- Conditions
- Diet, Healthy, Blood Sugar; High, Diabetes, Appetite and General Nutritional Disorders, Appetitive Behavior
- Interventions
- WR, LB, MB, HB, WR+50g HFCS, LB + 50 g HFCS, MB + 50 g HFCS, HB + 50 g HFCS
- Other
- Lead sponsor
- Washington State University
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 16 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- Spokane, Washington
- Conditions
- Insulin Resistance, Insulin Sensitivity, Pre Diabetes
- Interventions
- High fructose, fructose labeled meal, High fructose, pyruvate labeled meal, Low fructose, fructose labeled meal, Low fructose, pyruvate labeled meal
- Other
- Lead sponsor
- Touro University, California
- Other
- Eligibility
- 20 Years to 55 Years
- Enrollment
- 35 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2027
- U.S. locations
- 1
- States / cities
- Vallejo, California
- Conditions
- Healthy Participants, Obese But Otherwise Healthy Participants
- Interventions
- High fructose meal, Low fructose meal, 13C labeled fructose, oral, 13C labeled fructose, intravenous
- Other
- Lead sponsor
- Touro University, California
- Other
- Eligibility
- 20 Years to 55 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2030
- U.S. locations
- 1
- States / cities
- Vallejo, California
- Conditions
- Hyperinsulinemic Hypoglycemia
- Interventions
- high carbohydrate test meal, high carbohydrate test meal after pre-treatment with rapid acting aspart insulin, high fructose , low glucose test meal with carbohydrate and caloric content similar to the control meal
- Other
- Lead sponsor
- University of Minnesota
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota
- Conditions
- Non-alcoholic Fatty Liver Disease, Diabetes
- Interventions
- Dietary intervention (calorie restricted diet)
- Other
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 41 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2007 – 2012
- U.S. locations
- 1
- States / cities
- Vallejo, California
- Conditions
- Sciatica
- Interventions
- Topiramate
- Drug
- Lead sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
- NIH
- Eligibility
- Not listed
- Enrollment
- 65 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2005
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
- Conditions
- Metabolic Syndrome, Obesity, Dyslipidemias
- Interventions
- Carbohydrate restricted group, Standard low fat diet
- Other
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 10 Years to 18 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 2
- States / cities
- Birmingham, Alabama
- Conditions
- Diabetes Mellitus, Type 2, Hyperuricemia
- Interventions
- Low-fructose diet, isocaloric, Allopurinol, Placebo, Low-fructose, hypocaloric
- Other · Drug
- Lead sponsor
- University of Missouri-Columbia
- Other
- Eligibility
- 40 Years to 75 Years
- Enrollment
- 34 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Columbia, Missouri
- Conditions
- Olipop, Poppi, Coca Cola - Classic, Diet Coke
- Interventions
- Prebiotic Soda 1, Prebiotic Soda 2, Diet Soda, Regular Coke
- Other
- Lead sponsor
- Texas Christian University
- Other
- Eligibility
- 18 Years to 40 Years · Male only
- Enrollment
- 10 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Fort Worth, Texas
- Conditions
- Non-alcoholic Fatty Liver Disease, Childhood Obesity, Insulin Resistance
- Interventions
- Carbohydrate-restricted diet, Control, low-fat diet
- Other
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 9 Years to 17 Years
- Enrollment
- 27 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Hypoglycemia; Iatrogenic
- Interventions
- Low Fructose, Saline, Somatostatin, Insulin, Glucagon, Dextrose solution, High Fructose
- Drug
- Lead sponsor
- Jason Winnick
- Other
- Eligibility
- 21 Years to 40 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2028
- U.S. locations
- 1
- States / cities
- Cincinnati, Ohio
- Conditions
- Fasting, Non-alcoholic Fatty Liver Disease (NAFLD)
- Interventions
- Fasting, Diet, oral carbohydrate challenge
- Behavioral · Dietary Supplement
- Lead sponsor
- Beth Israel Deaconess Medical Center
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2009 – 2023
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Cocaine Use Disorder
- Interventions
- Cocaine, Placebo, Phentermine, Topiramate
- Drug
- Lead sponsor
- University of Kentucky
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 38 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2019
- U.S. locations
- 1
- States / cities
- Lexington, Kentucky
- Conditions
- Healthy Volunteers
- Interventions
- Propranolol, Pindolol, Dantrolene, Magnesium Sulfate, Caffeine, Qsymia, Topiramate, Phentermine, Naltrexone, Mirabegron 50mg, Mirabegron 200mg, Placebo Cohort 1, Placebo Cohort 2, Placebo for Mirabegron
- Drug · Behavioral
- Lead sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- NIH
- Eligibility
- 18 Years to 35 Years · Male only
- Enrollment
- 47 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2024
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
- Conditions
- Body Weight Changes
- Interventions
- 40% Fat Diet, 20% Fructose Beverage, 20% Glucose Beverage
- Other
- Lead sponsor
- Pennington Biomedical Research Center
- Other
- Eligibility
- 28 Years to 55 Years
- Enrollment
- 19 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2009 – 2015
- U.S. locations
- 1
- States / cities
- Baton Rouge, Louisiana
- Conditions
- Non-alcoholic Fatty Liver Disease
- Interventions
- Experimental: Low-fructose, reduced carbohydrate diet, General Healthy Diet
- Behavioral
- Lead sponsor
- University of Wisconsin, Madison
- Other
- Eligibility
- 11 Years to 17 Years
- Enrollment
- 28 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2017
- U.S. locations
- 1
- States / cities
- Madison, Wisconsin
- Conditions
- Metabolic Syndrome, Inflammation, Hypertriglyceridemia, Obesity
- Interventions
- Aronia berry juice, Sham comparator
- Dietary Supplement · Other
- Lead sponsor
- Montana State University
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- Bozeman, Montana