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ClinicalTrials.gov public records Last synced Nov 15, 2026, 1:40 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 241 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Low level light therapy Clear all

Conditions: Alopecia
Interventions: LLLT; Device
Lead sponsor: Freedom Laser Therapy, Inc.; Industry
Eligibility: 18 Years to 70 Years · Female only
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 2
States / cities: Mendham, New Jersey • Great Neck, New York

Conditions: Depression, Major Depressive Disorder
Interventions: Transcranial Light Therapy, Sham Transcranial Light Therapy; Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 70 Years
Enrollment: 49 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 2
States / cities: Boston, Massachusetts • Orangeburg, New York

Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: Photobiomodulation Therapy, Placebo; Other
Lead sponsor: Marquette University; Other
Eligibility: 20 Years to 60 Years
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Glucose Control
Interventions: High Intensity Interval Training, Moderate Intensity aerobic training; Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Low Back Pain
Interventions: Erchonia MLS, Placebo Laser; Device
Lead sponsor: Erchonia Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 2
States / cities: Chandler, Arizona • Scottsdale, Arizona

Conditions: Reperfusion Injury, Post Cardiac Arrest Brain Injury
Interventions: LUTICIA - Light Utilization COX-Inhibitory Device); Device
Lead sponsor: Mitovation, Inc; Industry
Eligibility: 48 Hours to 1 Year
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Transitional Cell Cancer of Renal Pelvis and Ureter
Interventions: padeliporfin VTP; Drug
Lead sponsor: Steba Biotech S.A.; Other
Eligibility: 18 Years and older
Enrollment: 89 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2028
U.S. locations: 12
States / cities: Irvine, California • Los Angeles, California • Atlanta, Georgia + 9 more

Conditions: Aging
Interventions: Medx Console System, Sham Medx Console System, Vielight 810 intranasal stand alone unit, Sham Vielight 810 intranasal stand alone unit; Device
Lead sponsor: University of Florida; Other
Eligibility: 65 Years to 89 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2026
U.S. locations: 2
States / cities: Tucson, Arizona • Gainesville, Florida

Conditions: Sports-related Concussion
Interventions: Photobiomodulation therapy (PBMt), Standard of Care; Device · Other
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 13 Years to 18 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Pain, Chronic
Interventions: Float-REST, Nappod; Other
Lead sponsor: West Virginia University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Morgantown, West Virginia

Conditions: Chronic Knee Pain
Interventions: Photobiomodulation therapy (PBM) device, Sham PBM device; Device
Lead sponsor: University of Florida; Other
Eligibility: 50 Years to 99 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Healthy Participants, Mild Cognitive Impairment
Interventions: LLLT, Placebo; Device
Lead sponsor: University of Texas at Austin; Other
Eligibility: 45 Years and older
Enrollment: 91 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Alzheimer's Disease, Sleep Disturbance
Interventions: Active Lighting Intervention, Control Lighting Intervention; Device
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 65 Years and older
Enrollment: 135 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 2
States / cities: Albany, New York • New York, New York

Conditions: Surgery
Interventions: Low Level Laser Therapy; Device
Lead sponsor: University of Toledo Health Science Campus; Other
Eligibility: 18 Years to 85 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Toledo, Ohio

Conditions: Diabetic Peripheral Neuropathy
Interventions: Erchonia® FX-635™, Placebo Laser; Device
Lead sponsor: Erchonia Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Mesa, Arizona

Conditions: Body Contouring
Interventions: Erchonia ML Scanner (MLS), Sham device; Device
Lead sponsor: Erchonia Corporation; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 72 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2008
U.S. locations: 3
States / cities: Palm Beach Gardens, Florida • Marion, Indiana • Bloomfield Hills, Michigan

Conditions: Overweight and Obesity, Weight Loss
Interventions: Low Level Laser Therapy, Sham (placebo); Device · Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Pain Related to TMD
Interventions: THOR® laser system; Device
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 99 Years
Enrollment: 130 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Covid19
Interventions: Non-invasive red LLLT treatment to chest of patient., Sham Device Treatment; Device
Lead sponsor: Ward Photonics LLC; Industry
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Millsboro, Delaware

Conditions: Hearing Loss
Interventions: Low-level Laser Therapy, Placebo Comparator: Disabled Laser; Radiation · Other
Lead sponsor: University of Iowa; Other
Eligibility: 18 Years to 75 Years
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Suspected or Known Squamous Cell Neoplasia, Prior History of Squamous Cell Dysplasia and /or Neoplasia
Interventions: Proflavine Hemisulfate, Artificial Intelligence Mobile High-Resolution Microendoscope; Drug · Device
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 2
States / cities: Houston, Texas

Conditions: Photobiomodulation Therapy, Photomedicine, Low-Level Laser Therapy, Performance Enhancement, Quadriceps, Special Operations Readiness
Interventions: THOR3 training + Photobiomodulation Therapy (PBMT), THOR3 training + sham PBMT; Device
Lead sponsor: Musculoskeletal Injury Rehabilitation Research for Operational Readiness; Federal
Eligibility: 18 Years to 45 Years · Male only
Enrollment: 29 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Joint Base Lewis McChord, Washington

Conditions: Abscess
Interventions: Methylene Blue, Lipid Emulsion, Insertion of optical fiber, Laser Illumination (pre-defined dose), Optical Spectroscopy Measurement, Laser Illumination (patient-specific dose), Standard of care abscess drainage; Drug · Device · Procedure
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2032
U.S. locations: 2
States / cities: Rochester, New York

Conditions: Anxiety, PTSD, ADHD, Depression Disorders, Post-traumatic Stress, Substance Use, Executive Function, Sleep Disturbance
Interventions: AIP-Informed Integrative Psychotherapy, Transcutaneous Auricular Vagus Nerve Stimulation, Regulated Breathing and Autonomic Regulation, Audiovisual Entrainment, Vibroacoustic Stimulation, Breathwork-Based Auditory Driving Entropy Module (BADEM), Transcranial Electrical Stimulation; Behavioral · Device
Lead sponsor: Tactical Mind Research Coalition, Inc.; Other
Eligibility: 18 Years to 70 Years
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Tampa, Florida

Search by objective public record fields.

LLLT for Alopecia of the Eyebrow in Women

Transcranial Laser Therapy, Continuous and Pulsed Light, for Major Depressive Disorder (ELATED-3)

Photobiomodulation Therapy in Persons With Multiple Sclerosis

The Effect of High-Intensity Short-Duration Exercise Versus Moderate-Intensity High-Volume Exercise on Glucose Control

Study of Low Level Laser Therapy to Treat Low Back Pain

Light Utilization COX-Inhibitory Device Therapy for Infant Cardiac Arrest (LUTICA Study). The LUCID Device is Used in the Treatment of Ischemic Brain Reperfusion Injury Caused by Cardiac Arrest in Pediatric Patients.

ENdoluminal LIGHT ActivatED Treatment of Upper Tract Urothelial Cancer (ENLIGHTED) Study

Pilot Intervention With Near Infrared Stimulation

Assessing the Effects of Photobiomodulation on Clinical Recovery From Concussion in Adolescents

Examining the Effects of Float-REST for Recovery in Individuals With Chronic Lower Back Pain

Effects of Photobiomodulation on Inflammation and Chronic Pain in Knee Osteoarthritis (EPIC-KO)

Cognitive Enhancement Through Transcranial Laser Therapy

Methodology Issues in a Tailored Light Treatment for Persons With Dementia - Aim 2

Assessment of Low Level Laser Therapy for Late Postoperative Pain After Lumbar Fusion Surgery

Study of Low Level Laser Therapy to Treat Diabetic Peripheral Neuropathy Foot Pain

Study of Low Level Laser Therapy for Body Contouring

Low-level Laser and Lifestyle Modifications

Photobiomodulation for Management of Temporomandibular Disorder Pain

LLLT Treatment of Lung Inflammation in COVID-19

The Effect of Low-Level Laser Stimulation on Hearing Thresholds

Effectiveness and Performance of an Optical Biopsy Technology for Esophageal Cancer in Brazil and the United States

Photomedicine Project 14: PBMT for Performance Enhancement in SOF

Efficacy of Methylene Blue Photodynamic Therapy for Treatment of Deep Tissue Abscesses

Rapid Entrainment and Signal-guided Neuromodulation for Behavioral Health