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Showing 25–38 of 14 matching trials from the live ClinicalTrials.gov search.

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Filters: Intervention: Low tidal Volume Clear all

Conditions: Respiratory Insufficiency, Extracorporeal Membrane Oxygenation Complication, Mechanical Ventilation Pressure High
Interventions: Ultra-Protective Ventilation Facilitated by Extracorporeal Support, Lung-Protective Ventilation (LPV), Driving Pressure-Limited Ventilation (DPL), Lung- and Diaphragm-Protective Ventilation and Sedation (LDPVS), Early Cohort corticosteroid dose, Extended Cohort corticosteroid dose, Usual care without routine corticosteroids, Usual care without extending corticosteroids, Usual care with fludrocortisone, Usual care without fludrocortisone, Drug 4 mL:, Drug 40 mg:, PEEP-20, PEEP-AOP, PEEP-10, VV ECMO-facilitated strategy of earlier awakening, extubation and rehabilitation, Electrical impedance tomography (EIT), no treatment / intervention arm is involved., Usual care, Early Routine IMT; Other · Drug
Lead sponsor: University Health Network, Toronto; Other
Eligibility: 18 Years and older
Enrollment: 6,250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 26
States / cities: Tucson, Arizona • Los Angeles, California • San Diego, California + 19 more

Conditions: Acute Respiratory Failure
Interventions: Noninvasive positive pressure ventilation (NIPPV), Vapotherm; Device
Lead sponsor: Vapotherm, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 204 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 5
States / cities: Athens, Georgia • Florence, South Carolina • Chattanooga, Tennessee + 2 more

Conditions: Acute Respiratory Distress Syndrome
Interventions: Ventilator settings; Other
Lead sponsor: University of Medicine and Dentistry of New Jersey; Other
Eligibility: 18 Years to 65 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Newark, New Jersey

Conditions: Acute Lung Injury, Acute Respiratory Distress Syndrome
Interventions: Placement of an esophageal balloon measurements, Low tidal volume ventilation, Transpulmonary pressure-directed ventilation (EPVent); Procedure · Other
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2010
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Pancreaticoduodenectomy, Hepatectomy
Interventions: Normovolemic Hemodilution (ANH), Standard of care; Procedure
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 372 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2011
U.S. locations: 1
States / cities: New York, New York

Conditions: Acute Respiratory Distress Syndrome
Interventions: Multi-component LTVV implementation strategy; Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Burns
Interventions: Ventilation - High Frequency Percussive Ventilation, Ventilation - ARDSnet; Device
Lead sponsor: United States Army Institute of Surgical Research; Federal
Eligibility: 18 Years and older
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Fort Sam Houston, Texas

Conditions: Robotic Surgery, Post Operative Pulmonary Complications
Interventions: Low Intensity Mechanical Ventilation; Device
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Acute Lung Injury, Adult Respiratory Distress Syndrome
Interventions: low-tidal-volume ventilation, APRV; Other
Lead sponsor: Boston Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Acute Respiratory Distress Syndrome
Interventions: Ventilation strategy; Other
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Manual Ventilation
Interventions: Sotair; Device
Lead sponsor: SafeBVM; Industry
Eligibility: 18 Years and older
Enrollment: 102 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Acute Lung Injury, Adult Respiratory Distress Syndrome, Kidney Injury
Interventions: Volume-Cycled Assist-Control (AC) mode, Airway Pressure Release Ventilation (APRV) mode; Device
Lead sponsor: University of Tennessee, Chattanooga; Other
Eligibility: 18 Years to 85 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020
U.S. locations: 1
States / cities: Chattanooga, Tennessee

Conditions: Spinal Cord Injury, Respiratory Insufficiency
Interventions: Tidal volume used in mechanical ventilation; Procedure
Lead sponsor: Craig Hospital; Other
Eligibility: 18 Years to 55 Years
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Englewood, Colorado

Conditions: Acute Respiratory Distress Syndrome, ARDS, Respiratory Distress Syndrome, Acute, Respiratory Insufficiency, Respiratory Distress Syndrome, Shock Lung, Severe Acute Respiratory Syndrome
Interventions: Not listed
Lead sponsor: Intermountain Health Care, Inc.; Other
Eligibility: 18 Years and older
Enrollment: 8,692 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: Murray, Utah

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Platform of Randomized Adaptive Clinical Trials in Critical Illness

High Flow Therapy for the Treatment of Respiratory Failure in the ED

The Effects of Different Ventilator Strategies on Inflammation and Injury in Normal Lungs

Mechanical Ventilation, Directed by Esophageal Pressure Measurements, in Patients With Acute Lung Injury

Acute Normovolemic Hemodilution Versus Standard Intraoperative Management in Patients Having Hepatic Resection and Pancreaticoduodenectomy

A Strategy to Improve Implementation of LTVV for Patients w/ ARDS

BEST (Burn Center Evaluation of Standard Therapies) Ventilator Mode Study-

Low-Intensity Mechanical Ventilation in the Operating Room: a Pilot Study

Biomarkers of Lung Injury With Low Tidal Volume Ventilation Compared With Airway Pressure Release Ventilation

Effect of Low Tidal Volume Ventilation in Improving Oxygenation and Thus Reducing Acute Lung Injury in the Cardiac Surgical Patient

Prolonged Manual Ventilation Simulation

Airway Pressure Release Ventilation (APRV) Compared to ARDSnet Ventilation

A Comparison of High vs. Low Tidal Volumes in Ventilator Weaning for Individuals With Cervical Spinal Cord Injuries

Implementation of Lung Protective Ventilation in Patients With Acute Respiratory Failure