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Showing 25–43 of 19 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Low-Processed Food Diet Clear all
Completed Not applicable Interventional

Evaluation of Diet and Exercise in Patients With Non-Alcoholic Fatty Liver Disease

NCT00815009
View directory record Official record
Conditions
Fatty Liver
Interventions
Mod Fat/Low Processed Carb Diet and Moderate Exercise, Low Fat Diet and Moderate Exercise, Moderate Exercise Only
Behavioral
Lead sponsor
San Antonio Military Medical Center
Federal
Eligibility
18 Years to 70 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 15, 2012 · Synced Sep 25, 2026, 12:19 AM EDT
Completed Not applicable Interventional

Diet and Depression

NCT06252701
View directory record Official record
Conditions
Depression, Major Depressive Disorder, Weight Gain, Obesity, Metabolic Syndrome
Interventions
Reduction of Ultra-processed foods
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced Sep 25, 2026, 12:19 AM EDT
Active, not recruiting Not applicable Interventional

Diet and Health in Adults With Metabolic Syndrome

NCT03935048
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Higher protein, low glycemic load diet
Dietary Supplement
Lead sponsor
University of Arkansas, Fayetteville
Other
Eligibility
18 Years to 85 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Fayetteville, Arkansas
Source: ClinicalTrials.gov public record
Updated Aug 25, 2025 · Synced Sep 25, 2026, 12:19 AM EDT
Terminated Not applicable Interventional

How Gas-Filled Intragastric Balloons or Endoscopic Sleeve Gastroplasty Affect Hunger, Hunger Hormones, and Gastric Emptying Compared to Meal Replacements

NCT04306445
View directory record Official record
Conditions
Obesity
Interventions
GF-IGB: Obalon Balloon, Medically Supervised Meal Replacement Program: My New Weigh, Endoscopic sleeve gastroplasty: (ESG)
Device · Dietary Supplement · Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
22 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Sep 25, 2026, 12:19 AM EDT
Recruiting Not applicable Interventional

Effects of Ultra Processed Food on Intestinal Energy Harvest

NCT06853288
View directory record Official record
Conditions
Obesity and Overweight
Interventions
Diet containing 80% ultra processed foods, Diet containing 20% ultra processed foods
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
25 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Sep 25, 2026, 12:19 AM EDT
Completed Not applicable Interventional

Moderately Carbohydrate-restricted Diet to Treat NAFLD in Adolescents

NCT05268042
View directory record Official record
Conditions
Non-Alcoholic Fatty Liver Disease, Obesity
Interventions
Moderately carbohydrate-restricted diet, Fat-restricted diet
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
10 Years to 17 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 26, 2026 · Synced Sep 25, 2026, 12:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Return of First-phase Insulin Secretion in Type 2 Diabetes is Associated With Depletion of Pancreas Lipid

NCT03430310
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Low Glycemic Diet, Control Diet
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
35 Years to 65 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 23, 2024 · Synced Sep 25, 2026, 12:19 AM EDT
Recruiting Not applicable Interventional

Ultra Crave: An Investigation of Ultra-Processed Food

NCT06044285
View directory record Official record
Conditions
Food Addiction
Interventions
Low UP (meals provided), Low UP (self-guided), Active Control
Other
Lead sponsor
University of Michigan
Other
Eligibility
22 Years to 60 Years
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Sep 25, 2026, 12:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The UnProcessed Pantry Project (UP3)

NCT04241133
View directory record Official record
Conditions
Diet, Healthy, Diet Habit, Disease, Chronic, Health Behavior, Rural Health
Interventions
The UnProcessed Pantry Project (UP3)
Behavioral
Lead sponsor
Montana State University
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Bozeman, Montana
Source: ClinicalTrials.gov public record
Updated May 1, 2022 · Synced Sep 25, 2026, 12:19 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Pilot Test of Five Weight Neutral Interventions to Improve Health Among Adults of Higher Body Weight

NCT07363616
View directory record Official record
Conditions
Obesity & Overweight, Cardiometabolic Risk Factors
Interventions
Mediterranean eating style, Physical activity, Mindful Eating, Body Appreciation, Enjoyable Exercise
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Sep 25, 2026, 12:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mediterranean-like Unprocessed (CLEAN-MED) Diet Intervention Study of the Gut Microbiome of Healthy Adults

NCT05411120
View directory record Official record
Conditions
Diet Therapy
Interventions
Western Diet, CLEAN-MED
Other
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years to 60 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Sep 25, 2026, 12:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Functional Research of Emulsifiers in Humans

NCT03440229
View directory record Official record
Conditions
Healthy
Interventions
Emulsifier-containing diet
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 60 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 18, 2021 · Synced Sep 25, 2026, 12:19 AM EDT
Terminated Phase 2 Interventional Results available

Green Tea Extract in Treating Patients With Low-Risk Prostate Cancer

NCT01928485
View directory record Official record
Conditions
Stage I Prostate Cancer, Stage IIA Prostate Cancer, Stage IIB Prostate Cancer
Interventions
active surveillance, Sunphenon, laboratory biomarker analysis, Questionnaire Administration
Other · Drug
Lead sponsor
Sanjay Gupta PhD
Other
Eligibility
45 Years to 85 Years · Male only
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 21, 2020 · Synced Sep 25, 2026, 12:19 AM EDT
Completed Phase 1Phase 2 Interventional

The MHERO Study (Michigan's Hypertension, Diabetes, and Obesity Education Research Online)

NCT03729479
View directory record Official record
Conditions
Type2 Diabetes Mellitus, Hypertension, PreDiabetes, Overweight and Obesity
Interventions
DASH diet, Very low carbohydrate, ketogenic diet, Extras
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
21 Years to 70 Years
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 28, 2020 · Synced Sep 25, 2026, 12:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Biobehavioral Impact of Diet Quality on Affect and Craving

NCT04105712
View directory record Official record
Conditions
Food Addiction, Withdrawal
Interventions
Dietary Change (low in highly processed foods)
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
25 Years to 40 Years
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 31, 2021 · Synced Sep 25, 2026, 12:19 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Dietary Guidelines for Americans-Ultra Processed Study

NCT07252037
View directory record Official record
Conditions
Overweight , Obesity, Class I Obesity
Interventions
Low-processed DGA Diet, Ultra-processed DGA Diet
Other
Lead sponsor
USDA Grand Forks Human Nutrition Research Center
Federal
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Grand Forks, North Dakota
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Sep 25, 2026, 12:19 AM EDT
Withdrawn Not applicable Interventional

Effect of a Plant Rich Diet on in People With Type 2 Diabetes and Obesity

NCT02977039
View directory record Official record
Conditions
Type 2 Diabetes Mellitus in Obese
Interventions
NDPR diet, USDA healthy eating diet
Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 17, 2020 · Synced Sep 25, 2026, 12:19 AM EDT
Completed Not applicable Interventional Results available

Cryovagotomy Diabetes Trial

NCT04276051
View directory record Official record
Conditions
Diabetes Type 2, Diabetes Mellitus, Obesity
Interventions
Cryoablation of the Vagus Nerve, Lifestyle Intervention
Device · Behavioral
Lead sponsor
Emory University
Other
Eligibility
22 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
5
States / cities
Atlanta, Georgia • Johns Creek, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 7, 2023 · Synced Sep 25, 2026, 12:19 AM EDT
Terminated Not applicable Interventional

BREATHE-Easy Trial

NCT03200522
View directory record Official record
Conditions
Asthma
Interventions
Prudent diet, Western diet
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 13, 2021 · Synced Sep 25, 2026, 12:19 AM EDT