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ClinicalTrials.gov public records Last synced Oct 30, 2026, 4:40 AM EDT

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Showing 121–144 of 261 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: MONOVISC Clear all
Terminated Not applicable Interventional

Multicenter Ab-interno Glaucoma Study Investigating Canaloplasty

NCT04769453
View directory record Official record
Conditions
Primary Open Angle Glaucoma
Interventions
Canaloplasty using the iTrack microcatheter with Healon GV Pro, Canaloplasty using the Omni surgical system with Healon GV Pro, Canaloplasty using the iTrack microcatheter with Healon Pro, Canaloplasty using the Omni surgical system with Healon Pro
Device
Lead sponsor
Nova Eye, Inc.
Industry
Eligibility
22 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
7
States / cities
Glendale, Arizona • Beverly Hills, California • Orange, California + 4 more
Source: ClinicalTrials.gov public record
Updated Mar 15, 2023 · Synced Oct 30, 2026, 4:40 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Effect of TXA on Reducing Bruising After Filler Injection

NCT06665594
View directory record Official record
Conditions
Facial Filler Injections, Hyaluronic Acid, Tranexamic Acid
Interventions
Hyaluronic Acid (HA), Tranexamic Acid (TXA), Saline (placebo)
Procedure · Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 89 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 30, 2026, 4:40 AM EDT
Not yet recruiting Phase 2 Interventional Accepts healthy volunteers

Assess Impact of Microdroplet Hyaluronic Acid Filler on Skin Quality in Patients on Glucagon-like Peptide-1 Agonists

NCT07221461
View directory record Official record
Conditions
Wrinkle
Interventions
Skinvive
Device
Lead sponsor
Goldman, Butterwick, Fitzpatrick and Groff
Other
Eligibility
25 Years to 50 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 28, 2025 · Synced Oct 30, 2026, 4:40 AM EDT
Terminated Phase 4 Interventional

Gelclair at Conditioning or After Oral Mucositis Diagnosed vs. Magic Mouth Wash in Stem Cell Transplant Recipients

NCT03490396
View directory record Official record
Conditions
Oral Mucositis
Interventions
Gelclair, First® Mouthwash BLM
Device · Combination Product
Lead sponsor
Midatech Pharma US Inc.
Industry
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 22, 2019 · Synced Oct 30, 2026, 4:40 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Early Regenerative Intervention for Post-Traumatic Osteoarthritis

NCT04222140
View directory record Official record
Conditions
Post-Traumatic Osteoarthritis of Knee
Interventions
ERIPTO Protocol, BMAC Only
Combination Product · Biological
Lead sponsor
Affinity Health Research Institute
Other
Eligibility
25 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
3
States / cities
Aurora, Illinois • Oak Brook, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 9, 2020 · Synced Oct 30, 2026, 4:40 AM EDT
Terminated Phase 3 Interventional

Prospective Assessment of the Efficacy of Hyaluronate Knee Injections in Patients With Osteoarthritis

NCT00323778
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Hyalgan
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
45 Years to 90 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2006
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 6, 2008 · Synced Oct 30, 2026, 4:40 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

A Study of the Lifting Capacity of Fillers

NCT02974985
View directory record Official record
Conditions
Esthetic & Topographic Shifts From Facial Fillers
Interventions
injection of Restylane Lyft and Restylane L
Device
Lead sponsor
Abington Memorial Hospital
Other
Eligibility
40 Years to 60 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Plymouth Meeting, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 10, 2018 · Synced Oct 30, 2026, 4:40 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Study of Techniques of Subcutaneous Administration of Fluids Enabled by Human Recombinant Hyaluronidase

NCT00807885
View directory record Official record
Conditions
Dehydration
Interventions
hylenex-facilitated subcutaneous Lactated Ringer's infusion
Drug
Lead sponsor
Baxter Healthcare Corporation
Industry
Eligibility
18 Years to 60 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
2
States / cities
Lincoln, Nebraska • Neptune City, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 26, 2011 · Synced Oct 30, 2026, 4:40 AM EDT
Completed Not applicable Interventional Results available

A Pilot Study to Assess the Effectiveness and Safety of Belotero Balance® Injection for Volume Augmentation of the Infraorbital Hollow

NCT03777917
View directory record Official record
Conditions
Correction of Volume Loss in the Infraorbital Hollow Area
Interventions
Belotero Balance®
Device
Lead sponsor
Merz North America, Inc.
Industry
Eligibility
22 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
3
States / cities
Sarasota, Florida • New York, New York • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 14, 2023 · Synced Oct 30, 2026, 4:40 AM EDT
Completed Phase 4 Interventional

TREAD-20: Trial of Hyalgan Three Injection-Regimen for the Treatment of Knee Pain Due to Osteoarthritis

NCT00130468
View directory record Official record
Conditions
Osteoarthritis
Interventions
Hyalgan (sodium hyaluronate)
Drug
Lead sponsor
Sanofi
Industry
Eligibility
40 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Bridgewater, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 3, 2008 · Synced Oct 30, 2026, 4:40 AM EDT
Completed Not applicable Interventional Results available

Safety and Effectiveness of Restylane® Kysse for Lip Augmentation in Chinese Subjects

NCT05342753
View directory record Official record
Conditions
Lip Augmentation
Interventions
Restylane Kysse
Device
Lead sponsor
Galderma R&D
Industry
Eligibility
22 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
3
States / cities
Los Angeles, California • Vista, California • Ardmore, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Oct 30, 2026, 4:40 AM EDT
Enrolling by invitation Not applicable Interventional

Pilot Study to Evaluate the Efficacy and Safety of Xvie Delivered Into the Scalp by Microneedling in Women With Self-perceived Thinning Hair

NCT07221773
View directory record Official record
Conditions
Hair Thinning
Interventions
XVIE
Other
Lead sponsor
Restore Biologics Holdings, Inc. dba Xtressé
Industry
Eligibility
28 Years to 65 Years · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Maitland, Florida • Marriottsville, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 30, 2026, 4:40 AM EDT
Completed Not applicable Interventional

A Study to Evaluate the Safety and Effectiveness of Restylane-Defyne for Punctual Occlusion

NCT03709641
View directory record Official record
Conditions
Mild to Moderate Dry Eye Disease
Interventions
Restylane Defyne
Device
Lead sponsor
John C Meyer, MD
Other
Eligibility
21 Years to 80 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 10, 2018 · Synced Oct 30, 2026, 4:40 AM EDT
Recruiting Phase 2 Interventional

Efficacy and Safety Study of TPX-115 on Partial-thickness Rotator Cuff Tear

NCT07219654
View directory record Official record
Conditions
Partial Thickness Rotator Cuff Tears
Interventions
TPX-115, Cryopreserving hyaluronic acid medium, Saline
Biological · Other · Drug
Lead sponsor
Tego Science, Inc.
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
3
States / cities
La Mesa, California • Deerfield Beach, Florida • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 30, 2026, 4:40 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Evaluation of Filler Injection for Chin Profile Enhancement

NCT07777926
View directory record Official record
Conditions
Chin Regression, Chin Asymmetry, Jawline Contour Deficit
Interventions
HA Filler
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
22 Years to 55 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 30, 2026, 4:40 AM EDT
Completed Not applicable Interventional Results available

Sprinter Legend Balloon Catheter

NCT00961311
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Percutaneous Coronary Intervention, Sprinter Legend 1.25mm Balloon Catheter
Procedure · Device
Lead sponsor
Medtronic Vascular
Industry
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Oct 26, 2011 · Synced Oct 30, 2026, 4:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

An Investigation of ReNu™ Knee Injection in Patients With Osteoarthritis

NCT02318511
View directory record Official record
Conditions
Osteoarthritis
Interventions
Knee injection, ReNu amniotic allograft, placebo saline, Hyaluronic Acid
Procedure · Other · Device
Lead sponsor
NuTech Medical, Inc
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
12
States / cities
Birmingham, Alabama • Los Angeles, California • Chicago, Illinois + 8 more
Source: ClinicalTrials.gov public record
Updated Jan 18, 2020 · Synced Oct 30, 2026, 4:40 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Prospective Evaluation of Facial Cosmetic Procedures

NCT03460158
View directory record Official record
Conditions
Cosmetic Techniques
Interventions
Restylane-L®, Restylane-L® Lyft, Restylane Silk®
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
40 Years to 65 Years · Female only
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 27, 2024 · Synced Oct 30, 2026, 4:40 AM EDT
Completed Not applicable Interventional Results available

Randomized Evaluation of the Efficacy of Synvisc-One® for the Treatment of Patellofemoral Chondromalacia

NCT01771952
View directory record Official record
Conditions
Chondromalacia Patella, Patellofemoral Pain Syndrome
Interventions
Synvisc-One™, Sham Treatment
Device · Other
Lead sponsor
University of Virginia
Other
Eligibility
15 Years to 45 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 4, 2020 · Synced Oct 30, 2026, 4:40 AM EDT
Completed Phase 1 Interventional

Study to Evaluate the Safety and Preliminary Efficacy of IDCT, a Treatment for Symptomatic Lumbar Intervertebral Disc Degeneration

NCT03347708
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
IDCT, Saline Solution, Sodium Hyaluronate
Biological · Drug
Lead sponsor
DiscGenics, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
14
States / cities
Birmingham, Alabama • Los Angeles, California • San Diego, California + 11 more
Source: ClinicalTrials.gov public record
Updated Jan 25, 2023 · Synced Oct 30, 2026, 4:40 AM EDT
Completed Early Phase 1 Interventional

Early Anti-inflammatory Treatment in Patients With Acute ACL Tear and Painful Effusions

NCT03429140
View directory record Official record
Conditions
Anterior Cruciate Ligament
Interventions
Gel-One, Saline Placebo
Drug · Other
Lead sponsor
Cale Jacobs, PhD
Other
Eligibility
14 Years to 33 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Sep 13, 2022 · Synced Oct 30, 2026, 4:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Treatment of Forehead/Glabellar Rhytide Complex With Combination Botulinum Toxin A and Hyaluronic Acid Versus Botulinum Toxin A Injection Alone

NCT01186835
View directory record Official record
Conditions
Forehead/Glabellar Rhytid Complexes
Interventions
Combination Botulinum Toxin A and Hyaluronic Acid, Botulinum Toxin A
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 3, 2021 · Synced Oct 30, 2026, 4:40 AM EDT
Recruiting Early Phase 1 Interventional

HA35 Moderate Alcoholic Hepatitis (AH) Study

NCT05018481
View directory record Official record
Conditions
Alcoholic Hepatitis
Interventions
Sodium Hyaluronate, Placebo
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
21 Years to 65 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 30, 2026, 4:40 AM EDT
Withdrawn No phase listed Observational

Role of Hyaluronic Acid in Causing Cancer Stem Cell Growth in the Bones of Patients With Breast Cancer

NCT02331212
View directory record Official record
Conditions
Breast Carcinoma Metastatic to the Bone, Stage IV Breast Cancer
Interventions
Cytology Specimen Collection Procedure, Laboratory Biomarker Analysis
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
20 Years to 60 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 2, 2018 · Synced Oct 30, 2026, 4:40 AM EDT