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ClinicalTrials.gov public records Last synced Oct 23, 2026, 11:51 AM EDT

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Showing 409–432 of 1,432 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: MRI Brain Clear all
Terminated Phase 1 Interventional Accepts healthy volunteers Results available

PET Imaging of Neuroinflammation in Neurodegenerative Diseases Via a Novel Translocator Protein (TSPO) Radioligand

NCT03958630
View directory record Official record
Conditions
Dementia
Interventions
11C-ER176, 11C-PIB, Positron Emission Tomography (PET) Scan
Drug · Diagnostic Test
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated May 1, 2024 · Synced Oct 23, 2026, 11:51 AM EDT
Recruiting Not applicable Interventional

Magnetic Resonance (MR) Imaging to Determine High Risk Areas in Patients With Malignant Gliomas and to Design Potential Radiation Plans and to Examine Metabolite Changes in Gliomas and Other Solid Tumors

NCT00870129
View directory record Official record
Conditions
Brain Cancer, Glioma
Interventions
MRI and advanced MRI sequences
Procedure
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 23, 2026, 11:51 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Central Pain Syndrome in Survivors of Head and Neck Cancer

NCT04128267
View directory record Official record
Conditions
Head and Neck Cancer
Interventions
IPC-1000, Magnetic resonance imaging, Correlative Studies
Device · Other
Lead sponsor
Vanderbilt-Ingram Cancer Center
Other
Eligibility
21 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 19, 2022 · Synced Oct 23, 2026, 11:51 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Developing an EEG Paradigm to Study Prediction Error in Anorexia Nervosa

NCT04583774
View directory record Official record
Conditions
Anorexia Nervosa
Interventions
Prediction error tasks
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
11 Years to 17 Years · Female only
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 23, 2026, 11:51 AM EDT
Recruiting Phase 1Phase 2 Interventional

A Study to Evaluate the Safety and Effect of AVB-101, a Gene Therapy Product, in Subjects With a Genetic Sub-type of Frontotemporal Dementia (FTD-GRN)

NCT06064890
View directory record Official record
Conditions
Frontotemporal Dementia, FTD, FTD-GRN, Dementia, Frontotemporal
Interventions
Intrathalamic AAV.PGRN administration, Intrathalamic AVB-101
Procedure · Genetic
Lead sponsor
AviadoBio Ltd
Industry
Eligibility
30 Years to 75 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
3
States / cities
Columbus, Ohio • Nashville, Tennessee • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 23, 2026, 11:51 AM EDT
Recruiting Phase 1 Interventional

Papaverine in Combination With Chemoradiation for the Treatment of Stage II-III Non-small Cell Lung Cancer

NCT05136846
View directory record Official record
Conditions
Locally Advanced Lung Non-Small Cell Carcinoma, Stage II Lung Cancer AJCC v8, Stage IIA Lung Cancer AJCC v8, Stage IIB Lung Cancer AJCC v8, Stage III Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, Stage IIIC Lung Cancer AJCC v8, Unresectable Lung Non-Small Cell Carcinoma
Interventions
Carboplatin, Durvalumab, Paclitaxel, Papaverine, Radiation Therapy, Pemetrexed, Hypofractionated Radiation Therapy, Magnetic Resonance Imaging, Positron Emission Tomography, Computed Tomography, Magnetic Resonance Imaging of the Brain with and without Contrast, Biospecimen Collection
Drug · Biological · Radiation + 1 more
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
Duarte, California • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Oct 23, 2026, 11:51 AM EDT
Completed No phase listed Observational

Cerebral Lesions and Outcome After Cardiac Surgery (CLOCS)

NCT00391378
View directory record Official record
Conditions
Stroke, Cognitive Symptoms
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
363 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 23, 2026, 11:51 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Acute Ketone Supplementation on the Brain

NCT07711990
View directory record Official record
Conditions
Brain Health
Interventions
Ketone Ester Drink, Placebo
Dietary Supplement
Lead sponsor
Christopher Crabtree
Other
Eligibility
45 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 23, 2026, 11:51 AM EDT
Recruiting No phase listed Observational

Artificial Intelligence for Brain MRI Analysis in Epilepsy

NCT07881185
View directory record Official record
Conditions
Epilepsies
Interventions
Not listed
Lead sponsor
Istituto Giannina Gaslini
Other
Eligibility
Not listed
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
6
States / cities
Oakland, California • Washington D.C., District of Columbia • Chicago, Illinois + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Oct 23, 2026, 11:51 AM EDT
Completed No phase listed Observational Results available

Vertebrobasilar Flow Evaluation and Risk of Transient Ischemic Attack and Stroke (VERiTAS)

NCT00590980
View directory record Official record
Conditions
Vertebrobasilar Insufficiency, Ischemic Attack, Transient, Cerebrovascular Disorder, Brain Ischemia, Stroke
Interventions
Not listed
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
5
States / cities
Los Angeles, California • Chicago, Illinois • St Louis, Missouri + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Oct 23, 2026, 11:51 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Can Therapy Alter CNS Processing of Chronic Pain: A Longitudinal Study

NCT01794988
View directory record Official record
Conditions
Chronic Pain
Interventions
Group Cognitive Behavioral Therapy, Pain Education, Therapeutic Interactive Voice Response, NO TIVR
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years to 75 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2010
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Feb 20, 2013 · Synced Oct 23, 2026, 11:51 AM EDT
Recruiting Not applicable Interventional

Ultrasonic Debris Clearance to Promote Brain Resilience

NCT07573982
View directory record Official record
Conditions
Alzheimer s Disease, MCI With Increased Risk for Alzheimer Disease
Interventions
Ultrasonic Debris Clearance, sham
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 23, 2026, 11:51 AM EDT
Terminated Not applicable Interventional Results available

Neurofeedback in Individuals With Substance Use Disorders

NCT04188288
View directory record Official record
Conditions
Opioid-Related Disorders
Interventions
Experimental feedback, Control feedback, fMRI
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years to 50 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 25, 2024 · Synced Oct 23, 2026, 11:51 AM EDT
Suspended Phase 1Phase 2 Interventional

Repeated Super-selective Intraarterial Cerebral Infusion Of Bevacizumab Plus Carboplatin For Treatment Of Relapsed/Refractory GBM And Anaplastic Astrocytoma

NCT01386710
View directory record Official record
Conditions
Glioblastoma Multiforme, Anaplastic Astrocytoma
Interventions
Bevacizumab and Carboplatin
Drug
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Oct 23, 2026, 11:51 AM EDT
Enrolling by invitation Not applicable Interventional

An Examination of Cognitive and Sensorimotor Processes in Patients With Epilepsy

NCT00859794
View directory record Official record
Conditions
Epilepsy
Interventions
fMRI, Neuropsychological Testing, Additional electrode implantation, Electrical brain stimulation
Other
Lead sponsor
Northwell Health
Other
Eligibility
5 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2029
U.S. locations
1
States / cities
Great Neck, New York
Source: ClinicalTrials.gov public record
Updated Feb 1, 2024 · Synced Oct 23, 2026, 11:51 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

ReadMap: Reading in Stroke Alexia and Typical Aging

NCT06700005
View directory record Official record
Conditions
Aphasia, Stroke, Alexia
Interventions
Not listed
Lead sponsor
Georgetown University
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Oct 23, 2026, 11:51 AM EDT
Active, not recruiting Phase 4 Interventional

Efficacy of Clopidogrel on Incidence of Silent Brain Infarction

NCT04698031
View directory record Official record
Conditions
Silent Brain Infarction
Interventions
Clopidogrel treatment, Aspirin treatment
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 90 Years
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 23, 2026, 11:51 AM EDT
Completed Not applicable Interventional Results available

Ferumoxytol in Improving MR Imaging in Patients With High-Grade Brain Tumors or Cerebral Metastases

NCT00103038
View directory record Official record
Conditions
Central Nervous System Lymphoma, Malignant Glioma, Metastatic Malignant Neoplasm in the Brain
Interventions
3 Tesla Magnetic Resonance Imaging, Dynamic Contrast-Enhanced Magnetic Resonance Imaging, Dynamic Susceptibility Contrast-Enhanced Magnetic Resonance Imaging, Ferumoxytol, Gadolinium, MRI-Based Angiogram
Procedure · Drug
Lead sponsor
OHSU Knight Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2016
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 9, 2022 · Synced Oct 23, 2026, 11:51 AM EDT
Completed No phase listed Observational

Longitudinal Observational Biomarker Study

NCT05204940
View directory record Official record
Conditions
Depression, Dementia, Mild Cognitive Impairment
Interventions
Mechanisms of Late life depression (LLD)-dementia through functional Magnetic Resonance Imaging (fMRI), Neuropsychological Data, Clinical Scales
Behavioral
Lead sponsor
Centre for Addiction and Mental Health
Other
Eligibility
60 Years and older
Enrollment
506 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
4
States / cities
Los Angeles, California • St Louis, Missouri • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 25, 2024 · Synced Oct 23, 2026, 11:51 AM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Sensory-specific Peripheral Stimulation for Tremor Management

NCT04501133
View directory record Official record
Conditions
Parkinson's Disease, Essential Tremor
Interventions
Peripheral electrical stimulation, Single pulse TMS
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 80 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Oct 23, 2026, 11:51 AM EDT
Completed No phase listed Observational

Cerebral MRI During Sleep

NCT03304652
View directory record Official record
Conditions
Sleep
Interventions
Zaleplon, Natural Sleep
Drug · Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 59 Years
Enrollment
11 participants
Timeline
2017 – 2018
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 14, 2019 · Synced Oct 23, 2026, 11:51 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Examining Brain Changes Using Functional Magnetic Resonance Imaging (fMRI) in Amputees With Phantom Limb Pain Following Mirror Therapy

NCT00662415
View directory record Official record
Conditions
Phantom Limb Pain
Interventions
mirror-box treatment, observation
Device · Behavioral
Lead sponsor
United States Department of Defense
Federal
Eligibility
18 Years to 75 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 21, 2008 · Synced Oct 23, 2026, 11:51 AM EDT
Active, not recruiting Phase 2 Interventional

Testing the Anti-cancer Drug Erdafitinib for Brain Cancers That Have Returned or Progressed Following Treatment

NCT05859334
View directory record Official record
Conditions
Recurrent Glioma, Recurrent WHO Grade 2 Glioma, Recurrent WHO Grade 3 Glioma, Recurrent WHO Grade 4 Glioma
Interventions
Biospecimen Collection, Erdafitinib, Magnetic Resonance Imaging, Optical Coherence Tomography
Procedure · Drug
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
27
States / cities
Aurora, Colorado • Coral Gables, Florida • Deerfield Beach, Florida + 19 more
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Oct 23, 2026, 11:51 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

ADNI: Alzheimer's Disease Neuroimaging Initiative

NCT00106899
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
Magnetic Resonance Imaging (MRI), Positron Emission Tomography (PET), Lumbar Puncture (LP)
Procedure
Lead sponsor
Alzheimer's Disease Cooperative Study (ADCS)
Other
Eligibility
55 Years to 90 Years
Enrollment
818 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2011
U.S. locations
54
States / cities
Birmingham, Alabama • Phoenix, Arizona • Sun City, Arizona + 43 more
Source: ClinicalTrials.gov public record
Updated Sep 16, 2014 · Synced Oct 23, 2026, 11:51 AM EDT