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ClinicalTrials.gov public records Last synced Oct 21, 2026, 11:58 PM EDT

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Showing 361–384 of 702 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Manipulation Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Thoracic Mobilization on Shoulder Range of Motion

NCT01518504
View directory record Official record
Conditions
Shoulder Range of Motion in Healthy Individuals
Interventions
Thoracic Mobilization, Sham
Other
Lead sponsor
Creighton University
Other
Eligibility
19 Years to 45 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Nov 21, 2012 · Synced Oct 21, 2026, 11:58 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Activator and Type II Diabetics

NCT01782092
View directory record Official record
Conditions
Type II Diabetes
Interventions
Chiropractic Adjustment
Other
Lead sponsor
Life University
Other
Eligibility
30 Years to 60 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Marietta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 20, 2016 · Synced Oct 21, 2026, 11:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Social Media Effects on Lifestyle Satisfaction

NCT04253041
View directory record Official record
Conditions
Control Group, Social Media
Interventions
Effects of Instagram Exposure on Lifestyle Satisfaction
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
18 Years to 29 Years · Female only
Enrollment
98 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated May 1, 2020 · Synced Oct 21, 2026, 11:58 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Short-term Verbal Memory Endophenotype for Developmental Language Disorder Language Disorder

NCT06968169
View directory record Official record
Conditions
Developmental Language Disorder, Healthy Subjects
Interventions
Supportive learning, Cascades
Behavioral
Lead sponsor
Father Flanagan's Boys' Home
Other
Eligibility
5 Years to 10 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated May 13, 2025 · Synced Oct 21, 2026, 11:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Entertainment Media to Deliver Educational Messages About Mammography in Saudi Arabia

NCT05176405
View directory record Official record
Conditions
Breast Cancer, Behavior
Interventions
You-Tube Video: Elissa's EE song, Active Comparator: Standard of Care
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
40 Years to 69 Years · Female only
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 2, 2022 · Synced Oct 21, 2026, 11:58 PM EDT
Completed Phase 1 Interventional

Patients With Neck Pain Likely to Benefit From Thoracic Spine Thrust Mobilization

NCT00504686
View directory record Official record
Conditions
Neck Pain
Interventions
manual therapy, exercise
Other
Lead sponsor
Franklin Pierce University
Other
Eligibility
18 Years to 60 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Concord, New Hampshire
Source: ClinicalTrials.gov public record
Updated Feb 3, 2009 · Synced Oct 21, 2026, 11:58 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

A Comparative Study: Non-Surgical Spinal Decompression and Spinal Manipulative Therapy- Utilizing a Quantifiable Musculoskeletal Functional Assessment Risk Analysis Tool (MSDR®) in Patients With Chronic Low Back Pain

NCT00732394
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
MSDR
Other
Lead sponsor
MedAppraise, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Clearwater, Florida
Source: ClinicalTrials.gov public record
Updated Aug 12, 2008 · Synced Oct 21, 2026, 11:58 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effects of Two Different Dry-Needling Techniques for Low Back Pain

NCT03970486
View directory record Official record
Conditions
Low Back Pain
Interventions
Dry needling
Procedure
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 31, 2019 · Synced Oct 21, 2026, 11:58 PM EDT
Completed Not applicable Interventional

The Effect of Lumbopelvic Non-Thrust Spinal Manipulation on Individuals With Low Back Pain

NCT04646018
View directory record Official record
Conditions
Low Back Pain
Interventions
Lumbar Spine Manipulation, Sham Manipulation
Other
Lead sponsor
Alvernia University
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Reading, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 27, 2020 · Synced Oct 21, 2026, 11:58 PM EDT
Completed Not applicable Interventional Results available

Approach Bias Modification for the Treatment of Cannabis Use Disorder

NCT03629990
View directory record Official record
Conditions
Cannabis Use Disorder
Interventions
Approach Bias Modification (ABM), Sham ABM, Psychosocial therapy for cannabis use disorder.
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 17, 2024 · Synced Oct 21, 2026, 11:58 PM EDT
Withdrawn Not applicable Interventional

Effect of Acupuncture on Hypogalactia

NCT03851718
View directory record Official record
Conditions
Hypogalactia
Interventions
Acupuncture Procedure, Power pumping
Device · Behavioral
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated May 3, 2019 · Synced Oct 21, 2026, 11:58 PM EDT
Completed Not applicable Interventional

OMT & Intractable Singultus

NCT07149025
View directory record Official record
Conditions
Hiccup
Interventions
Osteopathic Manipulative Therapy
Procedure
Lead sponsor
Michigan State University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 29, 2025 · Synced Oct 21, 2026, 11:58 PM EDT
Completed No phase listed Observational

Pulmonary Compliance Changes During Manipulation of Early Onset Scoliosis and Cast Application

NCT02558985
View directory record Official record
Conditions
Scoliosis
Interventions
Casting
Procedure
Lead sponsor
Indiana University
Other
Eligibility
6 Months to 9 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 24, 2023 · Synced Oct 21, 2026, 11:58 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Rate of Torque Development and Voluntary Quadriceps Activation in Patients With Knee Osteoarthritis: A Quantitative Analysis Before and After a Single Session of Manual Physical Therapy

NCT04234282
View directory record Official record
Conditions
Knee Osteoarthritis, Knee Arthritis, Knee Pain Chronic, Knee Deformity, Knee Pain Swelling, Muscle Weakness, Muscle Weakness Condition, Power
Interventions
Manual Physical Therapy
Procedure
Lead sponsor
Jennifer Moreno Clinic
Other
Eligibility
45 Years to 74 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 21, 2020 · Synced Oct 21, 2026, 11:58 PM EDT
Completed Phase 2 Interventional Results available

Selective T-Cell Depletion to Reduce GVHD (Patients) Receiving Stem Cell Tx to Treat Leukemia, Lymphoma or MDS

NCT00025662
View directory record Official record
Conditions
Graft vs Host Disease, Myelodysplastic Syndromes, Leukemia, Leukemia, Myeloid, Leukemia, Myelomonocytic, Chronic, Leukemia, Lymphocytic, Lymphoma, Lymphoma, Mantle-cell, Lymphoma, Non-Hodgkin, Hodgkin Disease
Interventions
RFT5-SMPT-dgA, Isolex system
Drug
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years to 75 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2008
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 28, 2016 · Synced Oct 21, 2026, 11:58 PM EDT
Completed Not applicable Interventional Results available

Spine Pain INtervention to Enhance Care Quality And Reduce Expenditure

NCT03083886
View directory record Official record
Conditions
Back Pain, Neck Pain
Interventions
Identify, Coordinated, Enhanced (ICE) Decision Making + PCP led care, Individualized Postural Therapy (IPT) + PCP led care, Usual PCP led care
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
3,087 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
8
States / cities
Phoenix, Arizona • Laguna Hills, California • North Hollywood, California + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Oct 21, 2026, 11:58 PM EDT
Completed Not applicable Interventional Results available

Improving Veteran Access to Integrated Management of Back Pain

NCT04411420
View directory record Official record
Conditions
Low Back Pain, Veterans Family
Interventions
Pain modulation with physical pain treatment, Telephone delivered self-management counseling for increasing physical activity, Telephone delivered behavioral treatment for participants with high risk for continued disability, Patient preference treatment protocol, Nonpharmacological guideline adherent treatment protocol, Facilitated referrals to existing VA or non-VA pain management resources
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
1,817 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 27, 2025 · Synced Oct 21, 2026, 11:58 PM EDT
Completed Not applicable Interventional

Finger Movement Training After Stroke

NCT05621980
View directory record Official record
Conditions
Stroke
Interventions
Actuated Virtual Keyboard (AVK) system, Occupational Therapy (OT)
Behavioral
Lead sponsor
North Carolina State University
Other
Eligibility
21 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 21, 2026, 11:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Lumbopelvic Manipulation on Hip and Knee Neuromuscular Activity

NCT01637480
View directory record Official record
Conditions
Patellofemoral Pain Syndrome
Interventions
Lumbopelvic manipulation
Other
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 50 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 12, 2015 · Synced Oct 21, 2026, 11:58 PM EDT
Completed Not applicable Interventional

OMT as an Adjunctive Treatment in MDD

NCT05065580
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Osteopathic Manipulative Treatment
Procedure
Lead sponsor
Corewell Health South
Other
Eligibility
18 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Saint Joseph, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Oct 21, 2026, 11:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigating the Effects of Osteopathic Manipulative Treatment on Stress Management in Medical Students

NCT06125574
View directory record Official record
Conditions
Stress, Job, Student Burnout, Stress, Physiological, Stress, Psychological
Interventions
Osteopathic Manipulative Medicine
Other
Lead sponsor
The Touro College and University System
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 14, 2023 · Synced Oct 21, 2026, 11:58 PM EDT
Terminated Not applicable Interventional

OMT of Somatic Dysfunction and Chronic Low Back Pain in Patients With Type 2 Diabetes Mellitus

NCT02054650
View directory record Official record
Conditions
Chronic Low Back Pain, Type 2 Diabetes Mellitus
Interventions
Osteopathic Manual Treatment (OMT), Sham OMT
Other
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
18 Years to 79 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated May 26, 2016 · Synced Oct 21, 2026, 11:58 PM EDT
Not listed Phase 2Phase 3 Interventional

Manual Therapy in Addition to Pulmonary Rehabilitation in Moderate Chronic Obstructive Pulmonary Disease.

NCT04386590
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease Moderate
Interventions
Manual Therapy Plus Pulmonary Rehabilitation, Sham Intervention
Other
Lead sponsor
Canandaigua VA Medical Center
Federal
Eligibility
50 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Mar 31, 2022 · Synced Oct 21, 2026, 11:58 PM EDT
Withdrawn Not applicable Interventional

Effects of Chiropractic on Chronic Cancer-related Fatigue

NCT06235671
View directory record Official record
Conditions
Cancer, Fatigue
Interventions
Chiropractic care
Procedure
Lead sponsor
Life University
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 21, 2026, 11:58 PM EDT