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ClinicalTrials.gov public records Last synced Oct 23, 2026, 5:19 PM EDT

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Showing 649–672 of 702 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Manipulation Clear all
Completed Not applicable Interventional

OMT vs. Standard Therapy in the Management of Acute Neck and Low Back Pain in the Emergency Department

NCT06987578
View directory record Official record
Conditions
Acute Pain
Interventions
OMT vs. Ibruprofen
Other
Lead sponsor
St. Joseph's Regional Medical Center, New Jersey
Other
Eligibility
18 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Paterson, New Jersey
Source: ClinicalTrials.gov public record
Updated May 23, 2025 · Synced Oct 23, 2026, 5:19 PM EDT
Terminated Phase 1 Interventional

AGE Levels in ER+ Metastatic Breast Cancer Patients Receiving Endocrine Therapy

NCT03092635
View directory record Official record
Conditions
Breast Cancer
Interventions
OPC
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 6, 2025 · Synced Oct 23, 2026, 5:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Immediate Versus Delayed Debriefing on Basic Life Support Competence In Undergraduate Nursing Students.

NCT06624449
View directory record Official record
Conditions
BLS Competence, Debriefing
Interventions
Cold debriefing, Hot Debriefing
Behavioral
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 29, 2024 · Synced Oct 23, 2026, 5:19 PM EDT
Completed Not applicable Interventional Results available

Virtual Reality for Phantom Limb Pain

NCT02784548
View directory record Official record
Conditions
Phantom Limb Pain
Interventions
Virtual Reality
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 17, 2019 · Synced Oct 23, 2026, 5:19 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Osteopathic Manipulative Treatment and Migraine Headaches

NCT04976985
View directory record Official record
Conditions
Chronic Migraine, Migraine Disorders, Headache Disorders, Headache, Migraine
Interventions
Osteopathic Manipulative Therapy (OMT), Standard of care
Procedure · Other
Lead sponsor
St. Luke's Hospital, Pennsylvania
Other
Eligibility
18 Years to 50 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Bethlehem, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 3, 2021 · Synced Oct 23, 2026, 5:19 PM EDT
Recruiting Phase 2 Interventional

An Exploratory Study of the Potential for Rational Immune System Manipulation to Prevent Emergence of Synucleinopathy Manifestations in Persons With REM Sleep Behavior Disorder (RBD)

NCT06996652
View directory record Official record
Conditions
REM Sleep Behavior Disorder
Interventions
Adalimumab, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
50 Years to 80 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
18
States / cities
Los Angeles, California • Aurora, Colorado • North Haven, Connecticut + 14 more
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 23, 2026, 5:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Inflammatory Response to OMT

NCT06820684
View directory record Official record
Conditions
Inflammation, Inflammatory Response
Interventions
Osteopathic Manipulative Treatment (OMT)
Procedure
Lead sponsor
Pacific Northwest University of Health Sciences
Other
Eligibility
18 Years to 59 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Yakima, Washington
Source: ClinicalTrials.gov public record
Updated Feb 11, 2025 · Synced Oct 23, 2026, 5:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Stress, Sex, and the Generalization of Fear

NCT03786952
View directory record Official record
Conditions
Psychological Stress
Interventions
Stress immediately before learning in males, Sham control immediately before learning in males, Stress 30 minutes before learning in males, Sham control 30 minutes before learning in males, Stress immediately before learning in females, Sham control immediately before learning in females, Stress 30 minutes before learning in females, Sham control 30 minutes before learning in females
Behavioral
Lead sponsor
Ohio Northern University
Other
Eligibility
18 Years and older
Enrollment
606 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Ada, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 23, 2023 · Synced Oct 23, 2026, 5:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep and Cardiovascular Health in Adolescence

NCT03727906
View directory record Official record
Conditions
Insomnia Type; Sleep Disorder
Interventions
No pre-sleep arousal manipulation, pre-sleep arousal down-regulation, pre-sleep arousal up-regulation
Other
Lead sponsor
SRI International
Industry
Eligibility
16 Years to 20 Years
Enrollment
115 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Menlo Park, California
Source: ClinicalTrials.gov public record
Updated May 1, 2023 · Synced Oct 23, 2026, 5:19 PM EDT
Completed Not applicable Interventional

Effect of Osteopathic Manipulative Medicine on Motor Function and Quality of Life in Cervical Dystonia

NCT02420106
View directory record Official record
Conditions
Cervical Dystonia
Interventions
Osteopathic Manipulative Medicine
Procedure
Lead sponsor
New York Institute of Technology
Other
Eligibility
2 Years to 100 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Jul 2, 2019 · Synced Oct 23, 2026, 5:19 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

Chiropractic and Exercise Management of Spinal Dysfunction in Seniors

NCT01057706
View directory record Official record
Conditions
Neck Disability, Back Disability
Interventions
chiropractic, exercise
Other · Behavioral
Lead sponsor
Northwestern Health Sciences University
Other
Eligibility
65 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated May 6, 2015 · Synced Oct 23, 2026, 5:19 PM EDT
Completed Not applicable Interventional Results available

Variability In Hearing Aid Outcomes In Older Adults

NCT02448706
View directory record Official record
Conditions
Hearing Loss, Presbycusis
Interventions
Hearing Aid Fitting A, Hearing Aid Fitting B
Device
Lead sponsor
Northwestern University
Other
Eligibility
54 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 17, 2020 · Synced Oct 23, 2026, 5:19 PM EDT
Completed Not applicable Interventional

iEAT 2.0 Open Trial

NCT03383029
View directory record Official record
Conditions
Gastrointestinal Disorders
Interventions
iEAT Program
Behavioral
Lead sponsor
Emory University
Other
Eligibility
12 Months to 6 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 21, 2019 · Synced Oct 23, 2026, 5:19 PM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Dynamic Connectivity Under Metabolic Constraints

NCT04106882
View directory record Official record
Conditions
Insulin Resistance, Healthy, Diet Modification, Aging
Interventions
Ketones, Glucose
Drug
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years to 79 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2022
U.S. locations
2
States / cities
Charlestown, Massachusetts • Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Sep 27, 2019 · Synced Oct 23, 2026, 5:19 PM EDT
Terminated Not applicable Interventional

Chiropractic Prone Distraction for Lower Back Pain

NCT00269503
View directory record Official record
Conditions
Herniated Disc, Lower Back Pain, Sciatica
Interventions
Prone Distraction, Side-Posture Manipulation, Side-Posture Manipulation & Prone Distraction, Usual Care (Control Group)
Procedure
Lead sponsor
Samueli Institute for Information Biology
Other
Eligibility
18 Years to 45 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated May 8, 2008 · Synced Oct 23, 2026, 5:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Echinacea Purpurea and Osteopathy in Children With Recurrent Otitis Media

NCT00689468
View directory record Official record
Conditions
Otitis Media
Interventions
Cranial osteopathic manipulative treatment., Echinacea purpurea, Sham osteopathic manipulative treatment, "Echinacea purpurea" placebo
Procedure · Dietary Supplement
Lead sponsor
University of Arizona
Other
Eligibility
12 Months to 60 Months
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2002
U.S. locations
3
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 3, 2008 · Synced Oct 23, 2026, 5:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigating Neural Processing of Social Stimuli

NCT03380260
View directory record Official record
Conditions
Healthy Adults
Interventions
Paranoia Induction
Behavioral
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
18 Years to 55 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 28, 2021 · Synced Oct 23, 2026, 5:19 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Pranayama Practice on the Autonomic Nervous System

NCT03280589
View directory record Official record
Conditions
Pranayama Effect on Autonomic Nervous System, Respiration Variability Effect on Nervous System
Interventions
Sheetali/Sheekari Pranayama, Sitting Quietly, Deep breathing
Other
Lead sponsor
National University of Natural Medicine
Other
Eligibility
25 Years to 55 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 24, 2023 · Synced Oct 23, 2026, 5:19 PM EDT
Terminated Not applicable Interventional

OMT of Somatic Dysfunction and Chronic Low Back Pain in Patients With Type 2 Diabetes Mellitus

NCT02054650
View directory record Official record
Conditions
Chronic Low Back Pain, Type 2 Diabetes Mellitus
Interventions
Osteopathic Manual Treatment (OMT), Sham OMT
Other
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
18 Years to 79 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated May 26, 2016 · Synced Oct 23, 2026, 5:19 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Effects of an Acute Dose of a Betalain-rich Concentrate on Repeated-sprint Cycling Performance and Recovery.

NCT06274385
View directory record Official record
Conditions
Nutraceuticals
Interventions
Betalain-rich concentrate (AltRed), Placebo
Dietary Supplement · Other
Lead sponsor
Drexel University
Other
Eligibility
18 Years to 40 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 22, 2024 · Synced Oct 23, 2026, 5:19 PM EDT
Terminated Phase 1 Interventional

Pilot Study of Spinal Manipulation for Chronic Neck Pain

NCT00030004
View directory record Official record
Conditions
Neck Pain
Interventions
spinal manipulation, midazolam
Procedure · Drug
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2001
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Aug 18, 2006 · Synced Oct 23, 2026, 5:19 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

In Vitro Fertilization (IVF) and Prenatal Effects Independent of Genetics

NCT07296107
View directory record Official record
Conditions
Maternal Distress, Child Development
Interventions
Prenatal maternal psychosocial and biological assessment protocol
Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 23, 2026, 5:19 PM EDT
Completed Not applicable Interventional Results available

Effects of Cigarette and E-cigarette Flavors on Substitutability in the ETM

NCT06910202
View directory record Official record
Conditions
Cigarette Smoking Behavior
Interventions
Manipulation of nicotine/tobacco product price and availability
Behavioral
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
21 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 9, 2025 · Synced Oct 23, 2026, 5:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Direct Context Reactivation During Sleep on Memory

NCT04702152
View directory record Official record
Conditions
Sleep, Consolidation
Interventions
Targeted memory reactivation (sounds)
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 35 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 12, 2022 · Synced Oct 23, 2026, 5:19 PM EDT