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ClinicalTrials.gov public records Last synced Nov 6, 2026, 11:31 PM EST

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Showing 1–24 of 255 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Manual Therapy and Exercise Clear all

Conditions: Eating Disorders, Body Dissatisfaction
Interventions: Pregnant Body Project (PBP), Pregnancy Health Education (PHE); Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older · Female only
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Neck Pain Musculoskeletal, Neck Pain Treatment, Cervicalgia
Interventions: Cervical Manipulation, Exercise, Mobilization; Procedure
Lead sponsor: Baylor University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 4
States / cities: Rochester, Minnesota • Syracuse, New York • Waco, Texas + 1 more

Conditions: Total Thyroidectomy
Interventions: Anterior Neck Manual Therapy, Pain Neuroscience Education, Neck Stretches, Scar massage, Voice Exercises, Placebo Anterior Neck Manual Therapy, Placebo Pain Neuroscience Education, Placebo Neck Stretches; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 2
States / cities: Baltimore, Maryland • Bethesda, Maryland

Conditions: Cystic Fibrosis
Interventions: BMI and lean mass index from DXA, Anthropometric Measurements, Hand-grip strength, Six-minute walk Test, Sit-to-Stand Test, Short physical performance battery (SPPB), BIA Sub-study, Accelerometry to assess physical activity, Gastrointestinal (GI) and nutrition questionnaires:, Psychosocial questionnaire: PHQ-8, Psychosocial questionnaire: GAD-7, Psychosocial questionnaire: The Treatment Self-Regulation Questionnaire (TSRQ), Psychosocial questionnaire: CF Fatalism Scale, Psychosocial questionnaire: Body Esteem Scale for Adolescents and Adults (BESAA), 12-month Questionnaire, Oral glucose tolerance testing (OGTT), Continuous glucose monitoring (CGM), Chest CT scans (When available within the past 6 months in medical records), Hologic Dual X-Ray Absorptiometry (DXA), Ultrasound Sub-study of assessment of appendage muscles using ultrasound, Psychosocial questionnaire: Hunger Vital Sign questionnaire, Respiratory symptom questionnaire: CRISS, Spirometry, Psychosocial questionnaire: Additional Health Questionnaire, CF Management Questionnaire, Food Frequency Questionnaire; Diagnostic Test · Other · Device
Lead sponsor: Jaeb Center for Health Research; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 23
States / cities: Tucson, Arizona • Little Rock, Arkansas • Atlanta, Georgia + 19 more

Conditions: Knee Osteoarthritis
Interventions: Physical Therapy; Other
Lead sponsor: Brooke Army Medical Center; Federal
Eligibility: Not listed
Enrollment: 18 participants
Timeline: 2018
U.S. locations: 1
States / cities: Fort Sam Houston, Texas

Conditions: Shoulder Adhesive Capsulitis
Interventions: Home based FES in combination with usual therapy; Device
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Prostate Cancer
Interventions: Physical Therapy; Other
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 18 Years and older · Male only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Obesity
Interventions: Smartphone App Participants (APP), Diabetes Prevention Program Participants (DPP); Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 524 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Heart Arrest, Implantable Defibrillator User, Physical Activity
Interventions: E-ICD Intervention; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 210 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Chronic Low Back Pain
Interventions: In-Clinic Physical Therapy, Telehealth Physical Therapy (Telerehabilitation); Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 64 Years
Enrollment: 1,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2030
U.S. locations: 3
States / cities: Baltimore, Maryland • Salt Lake City, Utah

Conditions: Major Depressive Disorder, Mood Disorders
Interventions: Rumination-Focused CBT, Relaxation-based Therapy; Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 14 Years to 17 Years
Enrollment: 183 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2029
U.S. locations: 3
States / cities: Columbus, Ohio • Salt Lake City, Utah

Conditions: Chronic Low-back Pain, Hip Impairments, Hip-spine Syndrome, Osteoarthritis
Interventions: Hip-focused rehabilitation intervention, Spine-focused rehabilitation intervention; Behavioral
Lead sponsor: University of Delaware; Other
Eligibility: 60 Years to 85 Years
Enrollment: 184 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 3
States / cities: Newark, Delaware • Durham, North Carolina • Pittsburgh, Pennsylvania

Conditions: Fasciitis, Plantar
Interventions: Physical therapy after initial podiatry visit, Usual care provided by podiatry; Other
Lead sponsor: Des Moines University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 95 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Des Moines, Iowa

Conditions: Femoroacetabular Impingement
Interventions: Arthroscopic Surgery, Physical Therapy; Procedure
Lead sponsor: Madigan Army Medical Center; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Tacoma, Washington

Conditions: Obesity, Overweight
Interventions: Move Healthier Intervention; Behavioral
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Lebanon, New Hampshire

Conditions: Bicep Tendinitis, Biceps; Tenosynovitis, Bicipital Tendinitis, Left Shoulder, Bicipital Tendinitis, Right Shoulder, Bicipital Tendinitis, Unspecified Shoulder, Biceps Tendon Disorder
Interventions: Dry Needling, Heavy Slow Load Exercise, Rotator cuff and scapular stabilization exercise program, Soft tissue mobilization; Other
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 64 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 2
States / cities: Aurora, Colorado • Boulder, Colorado

Conditions: Shoulder Pain, Neck Pain
Interventions: Noxipoint Therapy, Physical Therapy; Procedure
Lead sponsor: Pain Cure Center, California; Industry
Eligibility: 18 Years to 64 Years
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Smoking Cessation
Interventions: Internet-All Nations Breath of Life (I-ANBL), Honoring the Gift of Heart Health, Nicotine gum, Patch, or Lozenge or Zyban® or Chantix®; Other · Drug
Lead sponsor: Won Choi, PhD, MPH; Other
Eligibility: 18 Years and older
Enrollment: 251 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2019
U.S. locations: 2
States / cities: Kansas City, Kansas • Pablo, Montana

Conditions: Back Pain, Intervertebral Disc Degeneration
Interventions: Physical Therapy; Procedure
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 30 Years to 70 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Anxiety
Interventions: Dream Yoga Inspired Intervention, Sleep Health Enhancement program; Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 2
States / cities: Evanston, Illinois • Charlottesville, Virginia

Conditions: Knee Osteoarthritis, Knee Arthritis, Knee Pain Chronic, Knee Deformity, Knee Pain Swelling, Muscle Weakness, Muscle Weakness Condition, Power
Interventions: Manual Physical Therapy; Procedure
Lead sponsor: Jennifer Moreno Clinic; Other
Eligibility: 45 Years to 74 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: Fort Sam Houston, Texas

Conditions: ACL Injury, ACL - Anterior Cruciate Ligament Rupture, ACL Sprain, ACL Tear
Interventions: CBPT-ACLR, Education; Behavioral · Other
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 14 Years to 35 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 2
States / cities: Garfield Heights, Ohio • Nashville, Tennessee

Conditions: Pelvic Floor Disorders
Interventions: Flourish HEC, which contains BioNourish, Routine pelvic physical therapy; Device · Other
Lead sponsor: Vaginal Biome Science; Other
Eligibility: 18 Years and older · Female only
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 1
States / cities: Bellaire, Texas

Conditions: Neoplasms, Breast
Interventions: Physical Therapy; Other
Lead sponsor: University of South Carolina; Other
Eligibility: 18 Years and older
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Columbia, South Carolina

Search by objective public record fields.

Preventing Disordered Eating and Body Dissatisfaction Among High-risk Pregnant Individuals

Validating a Clinical Prediction Rule to Guide Manual Therapy and Exercise for Neck Pain Relief

Impact of Manual Therapy on Laryngeal Function Following Total Thyroidectomy

Strength and Muscle Related Outcomes for Nutrition and Lung Function in CF

Influence of Manual Physical Therapy on Habitual Activity in Knee Osteoarthritis

Feasibility, Usability and Preliminary Efficacy of Home-based FES Fro Adhesive Capsulitis

Pelvic Health and Physical Therapy to Improve Lives of Prostate Cancer Patients Undergoing Prostatectomy

Elements Vital to Treat Obesity Study

Effectiveness of Exercise After an ICD

Telerehabilitation for Patients With Chronic Low Back Pain (TeleBACK Clinical Trial)

Mechanisms of Rumination Change in Adolescent Depression

Manual Therapy and Strengthening for the Hip in Older Adults With Chronic Low Back Pain

Comparison of Usual Podiatric Care and Early Physical Therapy for Plantar Heel Pain

A Physical Therapy Program Versus Surgery for Femoroacetabular Impingement: Randomized Clinical Trial

Pilot Trial of the Move Healthier Group

Dry Needling and Exercise Versus Traditional Physical Therapy for Biceps Tendinitis

Noxipoint Therapy Versus Standard Physical Therapy Using Electrical Stimulation for Chronic Pain

Web-based Smoking Cessation Program for Tribal College Students

The Role of Disc Nutrition in the Etiology and Clinical Treatment of Disc Degeneration

Feasibility of a Mental-Health Intervention Based on Contemplative Sleep Practices

Rate of Torque Development and Voluntary Quadriceps Activation in Patients With Knee Osteoarthritis: A Quantitative Analysis Before and After a Single Session of Manual Physical Therapy

Improving ACL Reconstruction Outcomes: CBPT

Effects of Flourish HEC Vaginal Care System on Birth-Related Pelvic Floor Disorders

Early Rehabilitation for Breast Cancer - A Randomized Control Trial