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ClinicalTrials.gov public records Last synced Nov 4, 2026, 11:15 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 238 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Manual-based Behavioral Treatment Clear all

Conditions: Suicidal Thoughts and Behaviors
Interventions: JJ-COPES Training; Behavioral
Lead sponsor: Rhode Island Hospital; Other
Eligibility: 18 Years and older
Enrollment: 45 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Preschool Age Children, Preschool Education, Adverse Childhood Experience, Mental Health, Resilience, Minority Groups
Interventions: Mental health, positive coping strategies promoting self-regulation and adaptive skills, Standard care/School Readiness Condition; Behavioral · Other
Lead sponsor: Cleveland State University; Other
Eligibility: 24 Months to 66 Months
Enrollment: 38 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Parenting, Emotional Distress
Interventions: Dialectical Behavioral Therapy Skills + Parent Training; Behavioral
Lead sponsor: University of Oregon; Other
Eligibility: 18 Years and older
Enrollment: 3 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Eugene, Oregon

Conditions: Insomnia, Apnea
Interventions: Insomnia treatment & PAP adherence, General sleep education; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 50 Years and older
Enrollment: 125 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 2
States / cities: Sepulveda, California • West Los Angeles, California

Conditions: Lung Cancer, Nonsmall Cell, COPD, Self-Management, Physical Inactivity, Stress, Quality of Life
Interventions: Breathe Easier; Behavioral
Lead sponsor: University of South Carolina; Other
Eligibility: 21 Years and older
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Columbia, South Carolina

Conditions: Smoking, Alcoholism
Interventions: Cognitive Behavior Therapy for alcohol and smoking cessation, Nicoderm CQ nicotine patch, Placebo gum, Nicotine gum - Nicorette®; Behavioral · Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2006
U.S. locations: 1
States / cities: Newington, Connecticut

Conditions: Stress Disorders, Post-Traumatic
Interventions: Mantram Repetition Program (MRP), Present Centered Therapy (PCT); Behavioral
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years and older
Enrollment: 181 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 2
States / cities: San Diego, California • Bedford, Massachusetts

Conditions: Attention Deficit Hyperactivity Disorder
Interventions: ADHD Collaborative; Other
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: Not listed
Enrollment: 49 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Diabetes Mellitus, Type 2
Interventions: Empowerment and CBT Classes; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 50 Years and older
Enrollment: 121 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Smoking Cessation
Interventions: Nicotine Mini-Lozenge for 11 Months, Preparation Phase Behavioral Reduction Counseling, Preparation Phase Recycling Counseling, Preparation Phase Control Treatment, Cessation Phase Supportive Counseling, Cessation Phase Skill Training Counseling, Cessation Phase Brief Information, Cessation Phase Nicotine Patch + Nicotine Mini-Lozenge; Drug · Behavioral
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 1,154 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Alcohol Use Disorder
Interventions: CBT4CBT in the Black Church; Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older
Enrollment: 137 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 3
States / cities: New Haven, Connecticut

Conditions: Body Dysmorphic Disorder, Somatoform Disorders
Interventions: Cognitive behavioral therapy (CBT); Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2008
U.S. locations: 2
States / cities: Charlestown, Massachusetts • Providence, Rhode Island

Conditions: Mild Cognitive Impairment (MCI)
Interventions: Behavioral Activation (BA), Supportive Therapy (ST); Behavioral
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 65 Years and older
Enrollment: 221 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Chronic Low-back Pain
Interventions: Enhanced Self-Care (ESC), Acceptance and Commitment Therapy (ACT), Evidence-Based Exercise and Manual Therapy (EBEM), Duloxetine; Behavioral · Drug
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years and older
Enrollment: 1,014 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 12
States / cities: Redwood City, California • San Diego, California • San Francisco, California + 9 more

Conditions: Cannabis Use Disorder
Interventions: Motivational Enhancement Therapy plus Ecological Momentary Intervention, Enhanced Usual Care; Behavioral
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 18 Years to 26 Years
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Major Depressive Disorder
Interventions: Cognitive Behavioral Therapy (CBT), Escitalopram; Behavioral · Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 75 Years
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Depression, Ketosis
Interventions: Ketogenic Diet, NIH Toolbox, gradCPT, Resting-state fMRI, Task-fMRI, CGM/CKM, Blood Draw, Sleep Monitoring, Ketone/Glucose Monitoring, Body Composition, PHQ-9, WHO-5, SKID; Other · Biological · Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years to 30 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Opioid Use Disorder
Interventions: EMBED CDS, Nurse prompt to complete COWS, Provider Prompt, Patient facing materials, Optimized EMBED, Name of Intervention; Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 1,912 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 3
States / cities: Guilford, Connecticut • New Haven, Connecticut

Conditions: Obesity & Overweight, Cardiometabolic Health Indicators, Addiction, Eating Disorders, Mental Health
Interventions: GLP-1 Receptor Agonist Therapy, Structured Lifestyle Intervention; Drug · Behavioral
Lead sponsor: Texas Tech University; Other
Eligibility: 18 Years and older
Enrollment: 27 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Lubbock, Texas

Conditions: Obesity, Eating Disorders
Interventions: CBT; Procedure
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 60 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2006
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Attention Deficit and Disruptive Behavior Disorders
Interventions: Behavioral Parent Training (MATCH Protocol); Behavioral
Lead sponsor: New York University; Other
Eligibility: Up to 99 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020
U.S. locations: 1
States / cities: New York, New York

Conditions: Persistent Post-surgical Pain, Acceptance and Commitment Therapy, Substance Use Disorder
Interventions: ACT (Acceptance and Commitment Therapy); Behavioral
Lead sponsor: Barbara A Rakel; Other
Eligibility: 18 Years and older
Enrollment: 88 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Mindfulness, Sense of Belonging
Interventions: Meditation, Yoga; Behavioral
Lead sponsor: University of New Mexico; Other
Eligibility: 18 Years and older
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Sleep, Alzheimer Disease
Interventions: Behavioral sleep education, Education only; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 60 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 2
States / cities: Los Angeles, California • North Hills, California

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From Court to the Community

The Building Resilience Program: Examining Self-Regulation, Behavior, and Resilience in Under-Resourced Preschoolers With ACEs

Development of DBT/Parent Training Group Intervention

Novel Treatment of Comorbid Insomnia and Sleep Apnea in Older Veterans

Breathe Easier II: A Dyad-based Multiple Behavior Intervention

Combination Nicotine Replacement for Alcoholic Smokers

Mantram Repetition Meditation for Veterans With PTSD

Disseminating a Model Intervention to Promote Improved Attention-deficit Hyperactivity Disorder (ADHD) Care in the Community

Mood and Diabetes Empowerment & Improvement Training

The Long-Term Quitting (Smoking Cessation) Study

Black Church Treatment Study

Treatment Study Investigating New Cognitive Behavioral Therapy Treatment Manual for Body Dysmorphic Disorder

Preventing Cognitive Decline in African Americans With Mild Cognitive Impairment

The BEST Trial: Biomarkers for Evaluating Spine Treatments

Developing a Telehealth + mHealth Cannabis Use Intervention for Young Adults

Quantitative Electroencephalogram (QEEG) Predictors of Response to Psychotherapy Versus Antidepressant Treatment in Depression

Ketogenic Intervention in Depression

Adaptive Decision Support for Addiction Treatment Master

Tirzepatide Impact Assessment Study

Cognitive Therapy for Binge-Eating Disorder

Peer Professionals to Increase Capacity to Treat ADHD

Preventing Persistent Post-Surgical Pain and Opioid Use In At-Risk Veterans: Effect of ACT

Belongingness in Nursing Through Mindfulness - BEING Mindful: A Pilot Study

A Dyadic Sleep Intervention for Alzheimer's Disease Patients and Their Caregivers