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Showing 1–14 of 14 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Intervention: Medtronic Dual-Chamber Pacemaker Clear all
Completed Not applicable Interventional Results available

Efficacy Study of Pacemakers to Treat Slow Heart Rate in Patients With Heart Failure

NCT02145351
View directory record Official record
Conditions
Heart Failure With a Preserved Ejection Fraction, Heart Failure, Diastolic, Chronotropic Incompetence
Interventions
Rate adaptive atrial pacing using a dual-chamber pacemaker, Pacemaker system will be implanted but set to Pacing Off.
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 4, 2023 · Synced Sep 25, 2026, 9:05 AM EDT
Terminated Not applicable Interventional Results available

MIRACLE EF Clinical Study

NCT01735916
View directory record Official record
Conditions
Congestive Heart Failure, Left Bundle Branch Block, Systolic Heart Failure
Interventions
CRT-P Implant, CRT-P OFF
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
69
States / cities
Concord, California • La Jolla, California • Los Angeles, California + 62 more
Source: ClinicalTrials.gov public record
Updated Nov 5, 2017 · Synced Sep 25, 2026, 9:05 AM EDT
Not listed Not applicable Interventional

Physiologic Pacing for Symptomatic First-Degree Heart Block

NCT06245304
View directory record Official record
Conditions
Symptomatic First-degree Heart Block
Interventions
Dual chamber Medtronic pacemaker implantation., DDD-50 pacing program, AAI-DDD 50 pacing program
Device · Other
Lead sponsor
Ascension Health
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 6, 2024 · Synced Sep 25, 2026, 9:05 AM EDT
Completed Not applicable Interventional

SAVEPACe - Search AV Extension and Managed Ventricular Pacing for Promoting Atrio-Ventricular Conduction

NCT00284830
View directory record Official record
Conditions
Sick Sinus Syndrome, Heart Failure, Congestive, Atrial Fibrillation, Bradycardia, Ventricular Dysfunction
Interventions
Implantable Pulse Generators
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
1,070 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
63
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Conway, Arkansas + 60 more
Source: ClinicalTrials.gov public record
Updated Feb 28, 2008 · Synced Sep 25, 2026, 9:05 AM EDT
Completed No phase listed Observational

A Comparison of Rate Response Performance in Pacemaker Patients With an Indication of Sinus Node Dysfunction

NCT02027909
View directory record Official record
Conditions
Sinus Node Dysfunction
Interventions
Reprogramming dual chamber pacemaker
Device
Lead sponsor
Arun Rao
Other
Eligibility
60 Years to 95 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Kingsport, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 24, 2018 · Synced Sep 25, 2026, 9:05 AM EDT
Completed Not applicable Interventional Results available

Optimize RV Follow-up Selective Site Pacing Clinical Trial

NCT00949715
View directory record Official record
Conditions
Cardiac Pacing, Right Ventricular Pacing, Left Ventricular Ejection Fraction
Interventions
Medtronic or Vitatron Dual-Chamber Pacemaker, Medtronic SelectSecure 3830 Lead
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
10
States / cities
Des Moines, Iowa • Silver Spring, Maryland • Southfield, Michigan + 7 more
Source: ClinicalTrials.gov public record
Updated Feb 14, 2018 · Synced Sep 25, 2026, 9:05 AM EDT
Completed Not applicable Interventional Results available

PREFER (Pacemaker Remote Follow-Up Evaluation and Review)

NCT00294645
View directory record Official record
Conditions
Bradycardia, Arrhythmia
Interventions
Transtelephonic monitoring (TTM), Medtronic CareLink® Network
Other
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
Not listed
Enrollment
980 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
45
States / cities
Scottsdale, Arizona • Little Rock, Arkansas • Washington D.C., District of Columbia + 42 more
Source: ClinicalTrials.gov public record
Updated Oct 18, 2010 · Synced Sep 25, 2026, 9:05 AM EDT
Terminated Not applicable Interventional Results available

Cardiovascular and Neurohormonal Effects of Faster Atrial Pacing Rate

NCT00698139
View directory record Official record
Conditions
Heart Failure
Interventions
Medtronic Pacemaker
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 90 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 26, 2018 · Synced Sep 25, 2026, 9:05 AM EDT
Recruiting Not applicable Interventional

ELEVATE-HFpEF Clinical Study

NCT06678841
View directory record Official record
Conditions
Heart Failure With Preserved Ejection Fraction (HFpEF)
Interventions
Personalized cardiac pacing
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
40 Years and older
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
26
States / cities
Phoenix, Arizona • San Francisco, California • Hartford, Connecticut + 22 more
Source: ClinicalTrials.gov public record
Updated Aug 2, 2026 · Synced Sep 25, 2026, 9:05 AM EDT
Completed No phase listed Observational Results available

Imaging Study of Lead Implant for His Bundle Pacing

NCT03294317
View directory record Official record
Conditions
Cardiac Pacemaker, Artificial
Interventions
His bundle pacing
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
3
States / cities
Indianapolis, Indiana • Wilkes-Barre, Pennsylvania • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated May 31, 2021 · Synced Sep 25, 2026, 9:05 AM EDT
Completed Phase 3 Interventional

Efficacy of Implantable Defibrillator Therapy After a Myocardial Infarction

NCT00673842
View directory record Official record
Conditions
Myocardial Infarction, Sudden Death
Interventions
Implantable Cardioverter Defibrillator + Usual Care, Usual care
Device · Other
Lead sponsor
University of Calgary
Other
Eligibility
18 Years to 80 Years
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2024
U.S. locations
29
States / cities
Huntsville, Alabama • Lakewood, Colorado • Tampa, Florida + 23 more
Source: ClinicalTrials.gov public record
Updated May 29, 2025 · Synced Sep 25, 2026, 9:05 AM EDT
Terminated Not applicable Interventional Results available

Optimize RV Selective Site Pacing Clinical Trial

NCT00422669
View directory record Official record
Conditions
Cardiac Pacing, Artificial, Cardiac Pacemaker, Artificial
Interventions
Medtronic Dual-Chamber Pacemaker, Medtronic SelectSecure 3830 Lead
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
205 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
16
States / cities
Bridgeport, Connecticut • Clearwater, Florida • Hudson, Florida + 13 more
Source: ClinicalTrials.gov public record
Updated Jan 30, 2013 · Synced Sep 25, 2026, 9:05 AM EDT
Completed Not applicable Interventional Results available

Advisa MRI Clinical Study

NCT01110915
View directory record Official record
Conditions
Magnetic Resonance Imaging, Cardiac Pacemaker, Artificial
Interventions
Medtronic Advisa MRI Implantable Pulse Generator (IPG), Medtronic CapSureFix MRI™ active fixation MRI lead
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
Not listed
Enrollment
269 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
11
States / cities
Salinas, California • Orlando, Florida • West Des Moines, Iowa + 8 more
Source: ClinicalTrials.gov public record
Updated Apr 29, 2013 · Synced Sep 25, 2026, 9:05 AM EDT
Active, not recruiting No phase listed Observational

Characterizing Outcomes and Real-World Experience of Cardiac Physiologic Pacing (The CORE-CPP Study)

NCT06606288
View directory record Official record
Conditions
Heart Failure
Interventions
Conduction system pacing, Bi-ventricular pacing
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
Not listed
Enrollment
6,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2030
U.S. locations
1
States / cities
Mounds View, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 25, 2026, 9:05 AM EDT